Correspondence: Dra. I. Blanco. Unidad de Broncología. Departamento de Neumología. Hospital de la Santa Creu i Sant Pau. Sant Antoni M. Claret, 167. 08025 Barcelona. España
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"nombre" => "Isabel" "apellidos" => "Blanco" "email" => array:1 [ 0 => "iblancov@santpau.es" ] "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor1" ] ] ] 1 => array:2 [ "nombre" => "Carmen" "apellidos" => "Burgués" ] 2 => array:2 [ "nombre" => "Carmen" "apellidos" => "Puzo" ] ] "afiliaciones" => array:1 [ 0 => array:1 [ "entidad" => "Unidad de Broncología, Departamento de Neumología, Hospital de la Santa Creu i Sant Pau, Facultat de Medicina, Universitat Autònoma de Barcelona, Barcelona, Spain" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor1" "etiqueta" => "*" "correspondencia" => "Correspondence: Dra. I. Blanco. Unidad de Broncología. Departamento de Neumología. Hospital de la Santa Creu i Sant Pau. Sant Antoni M. Claret, 167. 08025 Barcelona. España" ] ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2006-03-14" "fechaAceptado" => "2006-05-30" "PalabrasClave" => array:2 [ "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key words" "identificador" => "xpalclavsec154583" "palabras" => array:4 [ 0 => "Lung cancer" 1 => "Endoscopic images" 2 => "Infiltration" 3 => "Tumor" ] ] ] "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec154584" "palabras" => array:4 [ 0 => "Cáncer de pulmón" 1 => "Imágenes endoscópicas" 2 => "Infiltración" 3 => "Masa" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "en" => array:1 [ "resumen" => "<p class="elsevierStyleSimplePara elsevierViewall">Endoscopists describe lung cancer lesions using varying terminology. This study aimed to assess the probability of neoplastic disease in terms of endoscopic findings expressed in an original classification system. The endoscopic lesions were classified as infiltrations (superficial lesions without a clear border with normal mucosa) or masses (exophytic lesions easily distinguished from the bronchial wall). Each lesion was categorized according to 3 grades reflecting probability of malignancy. A grade I infiltration was a lesion presenting 1 of the following characteristics: loss of luster, increased thickness, or redness, with a smooth surface. A grade II infiltration presented 2 of the aforementioned characteristics, with a rough surface. A grade III infiltration presented 3 of those characteristics. A grade I mass was an exophytic lesion with a smooth surface, uniformly colored. A grade II mass presented a smooth surface of a distinct color, and a grade III mass had a rough surface and irregular coloring. We assessed 377 patients with suspicion of neoplasm. Twenty-three percent of the infiltrations were grade I carcinomas, 74% were grade II, and 95% were grade III. Twenty-three percent of masses were grade I, 77% were grade II, and 97% were grade III. The probability of malignancy increased significantly with grade (P<.001) for both types of lesion. In summary, there is a positive correlation between the terms used and the probability of carcinoma. Most grade III lesions were carcinomas, but apparently innocuous grade I lesions could be carcinomas in a significant number of cases.</p>" ] "es" => array:1 [ "resumen" => "<p class="elsevierStyleSimplePara elsevierViewall">La descripción de lesiones endoscópicas en el cáncer de pulmón varía según el endoscopista. Este trabajo pretende evaluar la probabilidad de neoplasia en relación con los ha-llazgos endoscópicos según una clasificación original. Las lesiones endoscópicas se clasifican en: infiltración (lesión en superficie sin límite preciso con la mucosa normal) y masa (lesión exofítica, fácil de diferenciar de la pared). Cada lesión tiene 3 grados con relación a la probabilidad de malignidad. En la infiltración grado I, la lesión presenta una de las si-guientes características: pérdida de brillo, aumento de gro-sor o enrojecimiento, de superficie regular; en la infiltración grado II coinciden 2 de los cambios anteriores, con superficie irregular; en la infiltración grado III están presentes 3 de las características anteriores; la masa grado I es una lesión exofítica de superficie lisa y coloración uniforme; la masa grado II presenta una superficie regular de coloración distinta, y en la masa III la superficie y coloración son irregulares.</p><p class="elsevierStyleSimplePara elsevierViewall">Se evaluó a 377 pacientes con sospecha de neoplasia. Fueron carcinomas un 23% de las infiltraciones grado I, un 74% de las infiltraciones grado II y un 95% de las infiltraciones grado III. Por lo que respecta a las masas, fueron neoplasias el 23% de las de grado I, el 77% de las de grado II y el 97% de las de grado III. En ambos tipos de lesiones la probabilidad de malignidad aumenta de acuerdo con el grado (p < 0,001).</p><p class="elsevierStyleSimplePara elsevierViewall">En conclusión, existe una correlación positiva entre la terminología descrita y la probabilidad de carcinoma. En la mayoría de los casos las lesiones grado III son carcinomas, pero a su vez las lesiones grado I, aparentemente inofensi-vas, pueden ser carcinomas en un número significativo de los casos.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "REFERENCES" "seccion" => array:1 [ 0 => array:1 [ "bibliografiaReferencia" => array:14 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "GLOBOCAN 2002:cancer incidence" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "J Ferlay" 1 => "F Bray" 2 => "P Pisani" 3 => "DM Parkin" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Libro" => array:4 [ "titulo" => "Mortality and prevalence worldwide" "fecha" => "2004" "editorial" => "IARC Press" "editorialLocalizacion" => "Lyon" ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib2" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Cancer incidence and mortality in Europe 2004" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "P Boyle" 1 => "J Ferlay" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1093/annonc/mdi098" "Revista" => array:6 [ "tituloSerie" => "Ann Oncol" "fecha" => "2005" "volumen" => "16" "paginaInicial" => "481" "paginaFinal" => "488" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15718248" "web" => "Medline" ] ] ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib3" "etiqueta" => "3" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Cancer mortality trends in EU and acceding countries" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "MJ Quinn" 1 => "A D'Onofrio" 2 => "B Moller" 3 => "R Black" 4 => "C Martínez-García" 5 => "H Møller" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Ann Oncol" "fecha" => "2003" "volumen" => "14" "paginaInicial" => "1148" "paginaFinal" => "1152" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12853360" "web" => "Medline" ] ] ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib4" "etiqueta" => "4" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Bronchogenic carcinoma" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "WKC Morgan" 1 => "CE Andrews" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "LibroEditado" => array:2 [ "titulo" => "Textbook of pulmonary diseases" "serieFecha" => "1974" ] ] ] ] ] ] 4 => array:3 [ "identificador" => "bib5" "etiqueta" => "5" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:1 [ "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "RG Fraser" 1 => "JA Pare" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Libro" => array:4 [ "titulo" => "Diagnosis of diseases of the chest" "fecha" => "1978" "editorial" => "W. 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