Original Articles
Treatment and Course of Community-Acquired Pneumonia Caused by Atypical Pathogens
Ramón Fernández Álvarez
, Isabel Suárez Toste, Gemma Rubinos Cuadrado, Agustín Medina Gonzálvez, José Antonio Gullón Blanco, Isidro González Martín
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enelllano@terra.es
Correspondence: Dr. R. Fernández Álvarez. San Juan Bautista, 19, A. 38002 Santa Cruz de Tenerife. España
Correspondence: Dr. R. Fernández Álvarez. San Juan Bautista, 19, A. 38002 Santa Cruz de Tenerife. España
Servicio de Neumología, Hospital Universitario de Canarias, La Laguna, Santa Cruz de Tenerife, Spain
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Fernández Álvarez. San Juan Bautista, 19, A. 38002 Santa Cruz de Tenerife. España" ] ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2005-08-08" "fechaAceptado" => "2006-01-01" "PalabrasClave" => array:2 [ "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key words" "identificador" => "xpalclavsec154528" "palabras" => array:3 [ 0 => "Antibiotic treatment for pneumonia" 1 => "Community-acquired pneumonia" 2 => "A typical pneumonia" ] ] ] "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec154527" "palabras" => array:3 [ 0 => "Tratamiento antibiótico de la neumonía" 1 => "Neumonía adquirida en la comunidad" 2 => "Neumonía atípica" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "en" => array:1 [ "resumen" => "<span class="elsevierStyleSectionTitle">Objective</span><p class="elsevierStyleSimplePara elsevierViewall">To study the course of disease and outcomes in a group of patients with community-acquired pneumonia caused by atypical pathogens (<span class="elsevierStyleItalic">Mycoplasma pneumoniae, Legionella</span> species, <span class="elsevierStyleItalic">Coxiella burnetii</span>, and <span class="elsevierStyleItalic">Chlamydophila pneumoniae</span>) according to the empiric treatment received.</p> <span class="elsevierStyleSectionTitle">Patients and methods</span><p class="elsevierStyleSimplePara elsevierViewall">Of a total of 390 patients admitted to our hospital with pneumonia between January 1996 and February 2001, the causative microorganism was an atypical pathogen in 89 cases. Patients were divided retrospectively into 2 groups according to the empiric treatment they received: group A, who had received an antibiotic regimen (quinolones or macrolides) that provided coverage for atypical pathogens; and group B, who had received treatment that did not provide such coverage. Clinical course was assessed in terms of the differences between the 2 groups in length of hospital stay, radiographic resolution, readmission at 30 days after discharge, and mortality.</p> <span class="elsevierStyleSectionTitle">Results</span><p class="elsevierStyleSimplePara elsevierViewall">A total of 89 patients with pneumonia caused by atypical pathogens (39 in group A and 50 in group B) were studied. No significant between-group differences in the variables were found.</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p class="elsevierStyleSimplePara elsevierViewall">In this group of patients hospitalized for community-acquired pneumonia, antibiotic regimens providing coverage for atypical pathogens did not improve either clinical or radiographic evolution.</p>" ] "es" => array:1 [ "resumen" => "<span class="elsevierStyleSectionTitle">Objetivo</span><p class="elsevierStyleSimplePara elsevierViewall">Estudiar la evolución de un grupo de neumonías extrahospitalarias causadas por gérmenes atípicos (<span class="elsevierStyleItalic">Mycoplasma pneumoniae, Legionella</span> spp., <span class="elsevierStyleItalic">Coxiella burnetii y Chlamydophila pneumoniae</span>) en función del tratamiento empírico recibido.</p> <span class="elsevierStyleSectionTitle">Pacientes y métodos</span><p class="elsevierStyleSimplePara elsevierViewall">Entre enero de 1996 y febrero de 2001 ingresaron en nuestra unidad 390 casos de neumonía, de los que 89 estaban causados por gérmenes atípicos. Los pacientes se dividieron retrospectivamente en 2 grupos según el tratamiento empírico pautado: grupo A, al que se había proporcionado cobertura frente a gérmenes atípicos (quinolonas o macrólidos), y grupo B, al que no se había proporcionado dicha cobertura. Se estudió la evolución según las diferencias entre ambos grupos en la estancia hospitalaria, la resolución radiológica, el reingreso en el primer mes tras el alta y la mortalidad.</p> <span class="elsevierStyleSectionTitle">Resultados</span><p class="elsevierStyleSimplePara elsevierViewall">El grupo de estudio lo constituyeron 89 pacientes con neumonía causada por gérmenes atípicos (39 en el grupo A y 50 en el B). Las variables estudiadas no mostraron diferencias significativas entre ambos grupos.</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p class="elsevierStyleSimplePara elsevierViewall">En nuestra serie de neumonías extrahospitalarias la cobertura antibiótica frente a gérmenes atípicos no mejoró la evolución clínica y radiológica de los pacientes.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:1 [ "bibliografiaReferencia" => array:22 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Guidelines for the management of adults with community-acquired pneumonia" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "American Thoracic Society" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1164/ajrccm.163.7.at1010" "Revista" => array:6 [ "tituloSerie" => "Am J Respir Crit Care Med." 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| Year/Month | Html | Total | |
|---|---|---|---|
| 2024 November | 5 | 4 | 9 |
| 2024 October | 40 | 13 | 53 |
| 2024 September | 43 | 13 | 56 |
| 2024 August | 46 | 30 | 76 |
| 2024 July | 39 | 27 | 66 |
| 2024 June | 36 | 21 | 57 |
| 2024 May | 37 | 30 | 67 |
| 2024 April | 32 | 20 | 52 |
| 2024 March | 21 | 16 | 37 |
| 2024 February | 32 | 17 | 49 |
| 2023 March | 4 | 3 | 7 |
| 2023 February | 15 | 21 | 36 |
| 2023 January | 17 | 23 | 40 |
| 2022 December | 12 | 19 | 31 |
| 2022 November | 20 | 19 | 39 |
| 2022 October | 19 | 27 | 46 |
| 2022 September | 21 | 22 | 43 |
| 2022 August | 17 | 31 | 48 |
| 2022 July | 15 | 46 | 61 |
| 2022 June | 17 | 29 | 46 |
| 2022 May | 12 | 16 | 28 |
| 2022 April | 27 | 25 | 52 |
| 2022 March | 17 | 26 | 43 |
| 2022 February | 14 | 35 | 49 |
| 2022 January | 13 | 28 | 41 |
| 2021 December | 16 | 44 | 60 |
| 2021 November | 17 | 44 | 61 |
| 2021 October | 24 | 52 | 76 |
| 2021 September | 13 | 73 | 86 |
| 2021 August | 13 | 25 | 38 |
| 2021 July | 11 | 25 | 36 |
| 2021 June | 16 | 33 | 49 |
| 2021 May | 13 | 41 | 54 |
| 2021 April | 33 | 49 | 82 |
| 2021 March | 30 | 26 | 56 |
| 2021 February | 11 | 18 | 29 |
| 2021 January | 14 | 19 | 33 |
| 2020 December | 13 | 11 | 24 |
| 2020 November | 9 | 20 | 29 |
| 2020 October | 10 | 6 | 16 |
| 2020 September | 7 | 5 | 12 |
| 2020 August | 8 | 7 | 15 |
| 2020 July | 12 | 16 | 28 |
| 2020 June | 12 | 10 | 22 |
| 2020 May | 14 | 16 | 30 |
| 2020 April | 18 | 11 | 29 |
| 2020 March | 9 | 18 | 27 |
| 2020 February | 12 | 17 | 29 |
| 2020 January | 16 | 12 | 28 |
| 2019 December | 12 | 17 | 29 |
| 2019 November | 10 | 9 | 19 |
| 2019 October | 7 | 8 | 15 |
| 2019 September | 14 | 3 | 17 |
| 2019 August | 15 | 5 | 20 |
| 2019 July | 9 | 8 | 17 |
| 2019 June | 5 | 5 | 10 |
| 2019 May | 12 | 7 | 19 |
| 2019 April | 44 | 24 | 68 |
| 2019 March | 5 | 18 | 23 |
| 2019 February | 5 | 9 | 14 |
| 2019 January | 3 | 8 | 11 |
| 2018 December | 3 | 10 | 13 |
| 2018 November | 15 | 11 | 26 |
| 2018 October | 21 | 6 | 27 |
| 2018 September | 10 | 5 | 15 |
| 2018 May | 4 | 0 | 4 |
| 2018 April | 10 | 5 | 15 |
| 2018 March | 3 | 2 | 5 |
| 2018 February | 4 | 6 | 10 |
| 2018 January | 4 | 7 | 11 |
| 2017 December | 3 | 5 | 8 |
| 2017 November | 3 | 7 | 10 |
| 2017 October | 13 | 13 | 26 |
| 2017 September | 5 | 6 | 11 |
| 2017 August | 12 | 11 | 23 |
| 2017 July | 4 | 2 | 6 |
| 2017 June | 11 | 6 | 17 |
| 2017 May | 12 | 7 | 19 |
| 2017 April | 7 | 5 | 12 |
| 2017 March | 23 | 3 | 26 |
| 2017 January | 1 | 0 | 1 |
| 2016 December | 4 | 9 | 13 |
| 2016 November | 15 | 15 | 30 |
| 2016 October | 10 | 17 | 27 |
| 2016 September | 8 | 2 | 10 |
| 2016 August | 7 | 3 | 10 |
| 2016 July | 6 | 0 | 6 |
| 2016 March | 1 | 0 | 1 |
| 2016 February | 1 | 0 | 1 |
| 2015 December | 2 | 0 | 2 |
| 2015 October | 43 | 14 | 57 |
| 2015 September | 46 | 6 | 52 |
| 2015 August | 32 | 11 | 43 |
| 2015 July | 41 | 5 | 46 |
| 2015 June | 30 | 7 | 37 |
| 2015 May | 68 | 9 | 77 |
| 2015 April | 30 | 9 | 39 |
| 2015 March | 38 | 13 | 51 |
| 2015 February | 32 | 7 | 39 |
| 2015 January | 32 | 9 | 41 |
| 2014 December | 41 | 4 | 45 |
| 2014 November | 40 | 5 | 45 |
| 2014 October | 67 | 9 | 76 |
| 2014 September | 47 | 10 | 57 |
| 2014 August | 43 | 14 | 57 |
| 2014 July | 48 | 12 | 60 |
| 2014 June | 60 | 6 | 66 |
| 2014 May | 104 | 5 | 109 |
| 2014 April | 122 | 9 | 131 |
| 2014 March | 86 | 5 | 91 |
| 2014 February | 45 | 8 | 53 |
| 2014 January | 38 | 10 | 48 |
| 2013 December | 41 | 12 | 53 |
| 2013 November | 30 | 3 | 33 |
| 2013 October | 40 | 5 | 45 |
| 2013 September | 39 | 7 | 46 |
| 2013 August | 38 | 6 | 44 |
| 2013 July | 48 | 11 | 59 |
| 2013 June | 41 | 6 | 47 |
| 2013 May | 33 | 4 | 37 |
| 2013 April | 16 | 6 | 22 |
| 2013 March | 7 | 1 | 8 |
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