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        "resumen" => "<span class="elsevierStyleSectionTitle">Objective</span><p class="elsevierStyleSimplePara elsevierViewall">Few studies have been carried out to determine the prevalence of microorganisms causing exacerbations of chronic bronchitis in the community setting&#46; The aim of the present study was to determine the bacterial etiology of chronic bronchitis exacerbations in patients not requiring hospitalization&#46;</p> <span class="elsevierStyleSectionTitle">Patients and methods</span><p class="elsevierStyleSimplePara elsevierViewall">This observational&#44; cross-sectional&#44; multicenter study was carried out at the primary care level during 2 weeks &#40;in November 2001 and January 2002&#41;&#46; All laboratory work was carried out at a single center&#46; We studied 1947 patients with mild-moderate exacerbations treated by 650 primary care physicians&#46; All the sputum samples received for centralized processing were subject to Gram staining&#44; microscopic examination&#44; and bacterial culture&#46;</p> <span class="elsevierStyleSectionTitle">Results</span><p class="elsevierStyleSimplePara elsevierViewall">Out of 1537 cultures of sputum samples collected&#44; 498 had good cell quality for microscopic examination &#40;32&#46;4&#37;&#41;&#46; Of the 498 good quality samples analyzed&#44; 246 &#40;49&#46;4&#37;&#41; were positive and 468 isolates were obtained&#46; The most commonly isolated germ was <span class="elsevierStyleItalic">Streptococcus pneumonias</span> &#40;163 cases&#44; 34&#46;8&#37;&#41;&#44; followed by <span class="elsevierStyleItalic">Moraxella catarrhalis</span> &#40;112&#44; 23&#46;9&#37;&#41;&#44; and <span class="elsevierStyleItalic">Haemophilus influenzae</span> &#40;59&#44; 12&#46;6&#37;&#41;&#46; In 1&#46;2&#37; of the <span class="elsevierStyleItalic">S pneumoniae</span> isolates resistance was found to amoxicillin&#59; resistance to macrolides was found in 34&#46;3&#37;&#46; The antibiotics most commonly prescribed&#44; however&#44; were macrolides &#40;38&#46;3&#37; of the prescriptions&#41;&#46;</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleItalic">S pneumoniae</span> was the microorganism most frequently isolated in cases of chronic bronchitis exacerbation treatable in this outpatient setting&#46;</p>"
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        "resumen" => "<span class="elsevierStyleSectionTitle">Objetivo</span><p class="elsevierStyleSimplePara elsevierViewall">Pocos estudios se han efectnado en el &#225;mbito comunitario para conocer la prevalencia de microorganismos causantes de agudizaciones de la bronquitis cr&#243;nica&#46; El objetivo del presente estudio ha sido conocer la etiolog&#237;a bacteriana de la agudizaci&#243;n de la bronquitis cr&#243;nica en pacientes que no han requerido hospitalizaci&#243;n&#46;</p> <span class="elsevierStyleSectionTitle">Pacientes y m&#233;todos</span><p class="elsevierStyleSimplePara elsevierViewall">Se trata de un estudio observational&#44; transversal y multic&#233;ntrico&#44; efectuado en atenci&#243;n primaria de salud durante 2 semanas &#40;noviembre de 2001 y enero de 2002&#41; con un laboratorio central&#46; Participaron 1&#46;947 pacientes afectados de agudizaci&#243;n leve-moderada incluidos por un total de 650 m&#233;dicos de atenci&#243;n primaria&#46; Todas las muestras recibidas se procesaron en un laboratorio central con tinci&#243;n de Gram&#44; examen microsc&#243;pico de las muestras y cultivo bacteriano&#46;</p> <span class="elsevierStyleSectionTitle">Resultados</span><p class="elsevierStyleSimplePara elsevierViewall">Entre los 1&#46;537 cultivos de esputo recogidos&#44; 498 presentaron buena calidad celular microsc&#243;pica &#40;32&#44;4&#37;&#41;&#46; De las 498 muestras de esputo de calidad &#246;ptima analizadas&#44; fueron positivas 246 &#40;49&#44;4&#37;&#41; y se obtuvieron 468 aislamientos&#46; El germen m&#225;s com&#250;nmente aislado fue <span class="elsevierStyleItalic">Streptococcus pneumoniae</span>&#44; con 163 casos &#40;34&#44;8&#37;&#41;&#44; seguido de <span class="elsevierStyleItalic">Moraxella catarrhalis</span>&#44; con 112 &#40;23&#44;9&#37;&#41;&#44; y <span class="elsevierStyleItalic">Haemophilus influenzae</span>&#44; con 59 &#40;12&#44;6&#37;&#41;&#46; El 1&#44;2&#37; de los neumococos fueron resistentes a amoxicilina y un 34&#44;3&#37; a los macr&#243;lidos&#46; Los antibi&#243;ticos mayormente prescritos fueron&#44; sin embargo&#44; los macr&#243;lidos&#44; en el 38&#44;3&#37; de las ocasiones&#46;</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleItalic">S&#46; pneumoniae</span> constituye el microorganismo bacteriano que con m&#225;s frecuencia se a&#237;sla de los pacientes que sufren agudizaciones de la bronquitis cr&#246;nica que pueden ser tratados ambulatoriamente&#46;</p>"
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Original Articles
Bacterial Etiology of Chronic Bronchitis Exacerbations Treated by Primary Care Physicians
Carles Llora,
Corresponding author
cllor.larte.ics@gencat.net

Correspondence: Dr. C. Llor. Foixarda. 95. 43008 Tarragona. Espana
, Josep Maria Cotsb, Amadeo Herrerasc
a Centro de Salud Jaume I, Tarragona, Spain
b Centro de Salud Marina, Barcelona, Spain. Coordinador del Grupo de Trabajo de Enfermedades Infecciosas de la Sociedad Española de Medicina de Familia
c Médico, Sanofi-Aventis, Barcelona, Spain
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            "entidad" => "Centro de Salud Marina&#44; Barcelona&#44; Spain&#46; Coordinador del Grupo de Trabajo de Enfermedades Infecciosas de la Sociedad Espa&#241;ola de Medicina de Familia"
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          ]
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    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "fechaRecibido" => "2005-06-22"
    "fechaAceptado" => "2005-12-13"
    "PalabrasClave" => array:2 [
      "en" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Key words"
          "identificador" => "xpalclavsec154479"
          "palabras" => array:4 [
            0 => "Bronchitis"
            1 => "chronic"
            2 => "Acute exacerbation"
            3 => "Etiology"
          ]
        ]
      ]
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          "titulo" => "Palabras clave"
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          "palabras" => array:3 [
            0 => "Bronquitis cr&#243;nica"
            1 => "Agudizaci&#243;n"
            2 => "Etiolog&#237;a"
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        "resumen" => "<span class="elsevierStyleSectionTitle">Objective</span><p class="elsevierStyleSimplePara elsevierViewall">Few studies have been carried out to determine the prevalence of microorganisms causing exacerbations of chronic bronchitis in the community setting&#46; The aim of the present study was to determine the bacterial etiology of chronic bronchitis exacerbations in patients not requiring hospitalization&#46;</p> <span class="elsevierStyleSectionTitle">Patients and methods</span><p class="elsevierStyleSimplePara elsevierViewall">This observational&#44; cross-sectional&#44; multicenter study was carried out at the primary care level during 2 weeks &#40;in November 2001 and January 2002&#41;&#46; All laboratory work was carried out at a single center&#46; We studied 1947 patients with mild-moderate exacerbations treated by 650 primary care physicians&#46; All the sputum samples received for centralized processing were subject to Gram staining&#44; microscopic examination&#44; and bacterial culture&#46;</p> <span class="elsevierStyleSectionTitle">Results</span><p class="elsevierStyleSimplePara elsevierViewall">Out of 1537 cultures of sputum samples collected&#44; 498 had good cell quality for microscopic examination &#40;32&#46;4&#37;&#41;&#46; Of the 498 good quality samples analyzed&#44; 246 &#40;49&#46;4&#37;&#41; were positive and 468 isolates were obtained&#46; The most commonly isolated germ was <span class="elsevierStyleItalic">Streptococcus pneumonias</span> &#40;163 cases&#44; 34&#46;8&#37;&#41;&#44; followed by <span class="elsevierStyleItalic">Moraxella catarrhalis</span> &#40;112&#44; 23&#46;9&#37;&#41;&#44; and <span class="elsevierStyleItalic">Haemophilus influenzae</span> &#40;59&#44; 12&#46;6&#37;&#41;&#46; In 1&#46;2&#37; of the <span class="elsevierStyleItalic">S pneumoniae</span> isolates resistance was found to amoxicillin&#59; resistance to macrolides was found in 34&#46;3&#37;&#46; The antibiotics most commonly prescribed&#44; however&#44; were macrolides &#40;38&#46;3&#37; of the prescriptions&#41;&#46;</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleItalic">S pneumoniae</span> was the microorganism most frequently isolated in cases of chronic bronchitis exacerbation treatable in this outpatient setting&#46;</p>"
      ]
      "es" => array:1 [
        "resumen" => "<span class="elsevierStyleSectionTitle">Objetivo</span><p class="elsevierStyleSimplePara elsevierViewall">Pocos estudios se han efectnado en el &#225;mbito comunitario para conocer la prevalencia de microorganismos causantes de agudizaciones de la bronquitis cr&#243;nica&#46; El objetivo del presente estudio ha sido conocer la etiolog&#237;a bacteriana de la agudizaci&#243;n de la bronquitis cr&#243;nica en pacientes que no han requerido hospitalizaci&#243;n&#46;</p> <span class="elsevierStyleSectionTitle">Pacientes y m&#233;todos</span><p class="elsevierStyleSimplePara elsevierViewall">Se trata de un estudio observational&#44; transversal y multic&#233;ntrico&#44; efectuado en atenci&#243;n primaria de salud durante 2 semanas &#40;noviembre de 2001 y enero de 2002&#41; con un laboratorio central&#46; Participaron 1&#46;947 pacientes afectados de agudizaci&#243;n leve-moderada incluidos por un total de 650 m&#233;dicos de atenci&#243;n primaria&#46; Todas las muestras recibidas se procesaron en un laboratorio central con tinci&#243;n de Gram&#44; examen microsc&#243;pico de las muestras y cultivo bacteriano&#46;</p> <span class="elsevierStyleSectionTitle">Resultados</span><p class="elsevierStyleSimplePara elsevierViewall">Entre los 1&#46;537 cultivos de esputo recogidos&#44; 498 presentaron buena calidad celular microsc&#243;pica &#40;32&#44;4&#37;&#41;&#46; De las 498 muestras de esputo de calidad &#246;ptima analizadas&#44; fueron positivas 246 &#40;49&#44;4&#37;&#41; y se obtuvieron 468 aislamientos&#46; El germen m&#225;s com&#250;nmente aislado fue <span class="elsevierStyleItalic">Streptococcus pneumoniae</span>&#44; con 163 casos &#40;34&#44;8&#37;&#41;&#44; seguido de <span class="elsevierStyleItalic">Moraxella catarrhalis</span>&#44; con 112 &#40;23&#44;9&#37;&#41;&#44; y <span class="elsevierStyleItalic">Haemophilus influenzae</span>&#44; con 59 &#40;12&#44;6&#37;&#41;&#46; El 1&#44;2&#37; de los neumococos fueron resistentes a amoxicilina y un 34&#44;3&#37; a los macr&#243;lidos&#46; Los antibi&#243;ticos mayormente prescritos fueron&#44; sin embargo&#44; los macr&#243;lidos&#44; en el 38&#44;3&#37; de las ocasiones&#46;</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleItalic">S&#46; pneumoniae</span> constituye el microorganismo bacteriano que con m&#225;s frecuencia se a&#237;sla de los pacientes que sufren agudizaciones de la bronquitis cr&#246;nica que pueden ser tratados ambulatoriamente&#46;</p>"
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        "nota" => "<p class="elsevierStyleNotepara">This study received funding from Sanofi-Aventis&#46;</p>"
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ISSN: 15792129
Original language: English
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