Editorial
Serum Markers in Idiopathic Pulmonary Fibrosis. Implications for Prognosis
Orlando Acosta Fernández
Corresponding author
oacosta@comtf.es
Correspondence: Dr. O. Acosta Fernández. Servicio de Neumología. Hospital Universitario Nuestra Señora de la Candelaria. Ctra. del Rosario, s/n. 38010 Santa Cruz de Tenerife. España
Correspondence: Dr. O. Acosta Fernández. Servicio de Neumología. Hospital Universitario Nuestra Señora de la Candelaria. Ctra. del Rosario, s/n. 38010 Santa Cruz de Tenerife. España
Servicio de Neumología, Hospital Universitario Nuestra Señora de la Candelaria, Santa Cruz de Tenerife; Spain
Read
5120
Timeswas read the article
2421
Total PDF
2699
Total HTML
Share statistics
array:22 [ "pii" => "S1579212906605491" "issn" => "15792129" "doi" => "10.1016/S1579-2129(06)60549-1" "estado" => "S300" "fechaPublicacion" => "2006-08-01" "aid" => "60549" "copyright" => "Sociedad Española de Neumología y Cirugía Torácica (SEPAR)" "copyrightAnyo" => "2006" "documento" => "simple-article" "crossmark" => 0 "subdocumento" => "edi" "cita" => "Arch Bronconeumol. 2006;42:377-9" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 2657 "formatos" => array:3 [ "EPUB" => 98 "HTML" => 1651 "PDF" => 908 ] ] "itemSiguiente" => array:18 [ "pii" => "S1579212906605508" "issn" => "15792129" "doi" => "10.1016/S1579-2129(06)60550-8" "estado" => "S300" "fechaPublicacion" => "2006-08-01" "aid" => "60550" "copyright" => "Sociedad Española de Neumología y Cirugía Torácica (SEPAR)" "documento" => "article" "crossmark" => 0 "subdocumento" => "fla" "cita" => "Arch Bronconeumol. 2006;42:380-3" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 2354 "formatos" => array:3 [ "EPUB" => 91 "HTML" => 1500 "PDF" => 763 ] ] "en" => array:10 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Original Articles</span>" "titulo" => "Quantifying Plasma Levels of Transforming Growth Factor β<span class="elsevierStyleInf">1</span> in Idiopathic Pulmonary Fibrosis" "tienePdf" => "en" "tieneTextoCompleto" => 0 "tieneResumen" => array:2 [ 0 => "en" 1 => "es" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "380" "paginaFinal" => "383" ] ] "contieneResumen" => array:2 [ "en" => true "es" => true ] "contienePdf" => array:1 [ "en" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "María Molina-Molina, Sergio Lario, Patricio Luburich, José Ramírez, María Teresa Carrión, Antoni Xaubet" "autores" => array:6 [ 0 => array:2 [ "nombre" => "María" "apellidos" => "Molina-Molina" ] 1 => array:2 [ "nombre" => "Sergio" "apellidos" => "Lario" ] 2 => array:2 [ "nombre" => "Patricio" "apellidos" => "Luburich" ] 3 => array:2 [ "nombre" => "José" "apellidos" => "Ramírez" ] 4 => array:2 [ "nombre" => "María Teresa" "apellidos" => "Carrión" ] 5 => array:2 [ "nombre" => "Antoni" "apellidos" => "Xaubet" ] ] ] ] ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1579212906605508?idApp=UINPBA00003Z" "url" => "/15792129/0000004200000008/v1_201305150251/S1579212906605508/v1_201305150251/en/main.assets" ] "en" => array:11 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Editorial</span>" "titulo" => "Serum Markers in Idiopathic Pulmonary Fibrosis. Implications for Prognosis" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "377" "paginaFinal" => "379" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "Orlando Acosta Fernández" "autores" => array:1 [ 0 => array:4 [ "nombre" => "Orlando Acosta" "apellidos" => "Fernández" "email" => array:1 [ 0 => "oacosta@comtf.es" ] "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor1" ] ] ] ] "afiliaciones" => array:1 [ 0 => array:1 [ "entidad" => "Servicio de Neumología, Hospital Universitario Nuestra Señora de la Candelaria, Santa Cruz de Tenerife; Spain" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor1" "etiqueta" => "*" "correspondencia" => "Correspondence: Dr. O. Acosta Fernández. Servicio de Neumología. Hospital Universitario Nuestra Señora de la Candelaria. Ctra. del Rosario, s/n. 38010 Santa Cruz de Tenerife. España" ] ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2006-01-10" "fechaAceptado" => "2006-01-31" "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:1 [ "bibliografiaReferencia" => array:20 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "International Consensus Statement" "autores" => array:1 [ 0 => array:2 [ "colaboracion" => "Idiopathic pulmonary fibrosis" "etal" => false ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1164/ajrccm.161.2.ats3-00" "Revista" => array:6 [ "tituloSerie" => "Am J Respir Crit Care Med" "fecha" => "2000" "volumen" => "161" "paginaInicial" => "646" "paginaFinal" => "664" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10673212" "web" => "Medline" ] ] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib2" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Diagnóstico y tratamiento de las enfermedades intersticiales difusas" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "A Xaubet" 1 => "J Ancoechea" 2 => "R Blanquer" 3 => "C Montero" 4 => "F Morell" 5 => "F Rodríguez-Becerra" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Arch Bronconeumol" "fecha" => "2003" "volumen" => "39" "paginaInicial" => "580" "paginaFinal" => "600" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/14636495" "web" => "Medline" ] ] ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib3" "etiqueta" => "3" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Idiopathic interstitial pneumonias: CT features" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "D Lynch" 1 => "W Travis" 2 => "N Müller" 3 => "J Galvin" 4 => "D Hansell" 5 => "P Grenier" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1148/radiol.2361031674" "Revista" => array:6 [ "tituloSerie" => "Radiology" "fecha" => "2005" "volumen" => "236" "paginaInicial" => "10" "paginaFinal" => "21" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15987960" "web" => "Medline" ] ] ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib4" "etiqueta" => "4" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Clinical significance of histological classification of idiopathic interstitial pneumonia" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "K Flaherty" 1 => "G Toews" 2 => "W Travis" 3 => "T Colby" 4 => "E Kazerooni" 5 => "B Gross" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Eur Respir J" "fecha" => "2002" "volumen" => "19" "paginaInicial" => "275" "paginaFinal" => "283" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11866008" "web" => "Medline" ] ] ] ] ] ] ] ] 4 => array:3 [ "identificador" => "bib5" "etiqueta" => "5" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Idiopathic pulmonary fibrosis: new insights into pathogenesis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "P Noble" 1 => "R Homer" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.ccm.2004.04.003" "Revista" => array:6 [ "tituloSerie" => "Clin Chest Med" "fecha" => "2004" "volumen" => "25" "paginaInicial" => "749" "paginaFinal" => "758" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15564020" "web" => "Medline" ] ] ] ] ] ] ] ] 5 => array:3 [ "identificador" => "bib6" "etiqueta" => "6" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Cytokine network in the pathogenesis of idiopathic pulmonary fibrosis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "KM Antoniou" 1 => "MG Alexandrakis" 2 => "NM Siafakas" 3 => "D Bouros" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Sarcoidosis Vase Diffuse Lung Dis" "fecha" => "2005" "volumen" => "22" "paginaInicial" => "91" "paginaFinal" => "104" ] ] ] ] ] ] 6 => array:3 [ "identificador" => "bib7" "etiqueta" => "7" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "KL-6, a mucin-like glycoprotein, in bronchoalveolar lavage fluid from patients with interstitial lung disease" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "N Kohno" 1 => "Y Awaya" 2 => "T Oyama" 3 => "M Yamakido" 4 => "M Akiyama" 5 => "Y Inoue" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1164/ajrccm/148.3.637" "Revista" => array:6 [ "tituloSerie" => "Am Rev Respir Dis" "fecha" => "1993" "volumen" => "148" "paginaInicial" => "637" "paginaFinal" => "642" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8368634" "web" => "Medline" ] ] ] ] ] ] ] ] 7 => array:3 [ "identificador" => "bib8" "etiqueta" => "8" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Serum levels of KL-6 as a useful marker evaluating pulmonary fibrosis in patients with systemic sclerosis" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "K Yamane" 1 => "H Ihn" 2 => "M Kubo" 3 => "N Yasawa" 4 => "K Kikuchi" 5 => "Y Soma" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Rheumatol" "fecha" => "2000" "volumen" => "27" "paginaInicial" => "930" "paginaFinal" => "934" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10782818" "web" => "Medline" ] ] ] ] ] ] ] ] 8 => array:3 [ "identificador" => "bib9" "etiqueta" => "9" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Circulating KL-6 predicts the outcome of rapidly progressive idiopathic pulmonary fibrosis" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "A Yokohama" 1 => "N Khono" 2 => "H Hamada" 3 => "M Sakatani" 4 => "E Ueda" 5 => "K Kondo" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1164/ajrccm.158.5.9803115" "Revista" => array:6 [ "tituloSerie" => "Am J Respir Crit Care Med" "fecha" => "1998" "volumen" => "158" "paginaInicial" => "1680" "paginaFinal" => "1684" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9817725" "web" => "Medline" ] ] ] ] ] ] ] ] 9 => array:3 [ "identificador" => "bib10" "etiqueta" => "10" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "TIMP-1,-2,-3 and -4 in idiopathic pulmonary fibrosis. A prevailing nondegradative lung microenvironment?" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "M Selman" 1 => "V Ruiz" 2 => "S Cabrera" 3 => "L Segura" 4 => "R Ramírez" 5 => "R Barrios" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Am J Physiol Lung Cell Mol Physiol" "fecha" => "2000" "volumen" => "279" "paginaInicial" => "562" "paginaFinal" => "574" ] ] ] ] ] ] 10 => array:3 [ "identificador" => "bib11" "etiqueta" => "11" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Metalloproteinase and growth factor interactions; do they play a role in pulmonary fibrosis?" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "M Winkler" 1 => "J Fowlkes" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Am J Physiol Lung Cell Mol Physiol" "fecha" => "2002" "volumen" => "283" "paginaInicial" => "1" "paginaFinal" => "11" ] ] ] ] ] ] 11 => array:3 [ "identificador" => "bib12" "etiqueta" => "12" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Clinical significance of MCP-1 levels in BALF and serum in patients with interstitial lung diseases" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "M Suga" 1 => "K Yyonaga" 2 => "H Ichiasu" 3 => "N Saita" 4 => "H Yamasaki" 5 => "M Ando" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Eur Respir J" "fecha" => "1999" "volumen" => "14" "paginaInicial" => "376" "paginaFinal" => "382" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10515417" "web" => "Medline" ] ] ] ] ] ] ] ] 12 => array:3 [ "identificador" => "bib13" "etiqueta" => "13" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Serum surfactant proteins A and D as prognostic factors in idiopathic pulmonary fibrosis and their relationship to disease extent" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "H Takahashi" 1 => "T Fujishima" 2 => "H Koba" 3 => "S Murakami" 4 => "K Kurokawa" 5 => "Y Shibuya" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1164/ajrccm.162.3.9910080" "Revista" => array:6 [ "tituloSerie" => "Am J Respir Crit Care Med" "fecha" => "2000" "volumen" => "162" "paginaInicial" => "1109" "paginaFinal" => "1114" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10988138" "web" => "Medline" ] ] ] ] ] ] ] ] 13 => array:3 [ "identificador" => "bib14" "etiqueta" => "14" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Serum surfactant proteins-A and -D as biomarkers in idiopathic pulmonary fibrosis" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "K Greene" 1 => "TE King Jr" 2 => "Y Kuroki" 3 => "B Bucher-Bartelson" 4 => "GW Hunninghake" 5 => "LS Newman" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Eur Respir J" "fecha" => "2002" "volumen" => "19" "paginaInicial" => "439" "paginaFinal" => "446" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11936520" "web" => "Medline" ] ] ] ] ] ] ] ] 14 => array:3 [ "identificador" => "bib15" "etiqueta" => "15" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Comparative study of KL-6, SP-A, SP-D and MCP-1 as serum markers for interstitial lung diseases" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "H Ohnishi" 1 => "A Yokohama" 2 => "K Kondo" 3 => "H Hamada" 4 => "M Abe" 5 => "K Nishimura" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1164/ajrccm.165.3.2107134" "Revista" => array:6 [ "tituloSerie" => "Am J Respir Crit Care Med" "fecha" => "2002" "volumen" => "165" "paginaInicial" => "378" "paginaFinal" => "381" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11818324" "web" => "Medline" ] ] ] ] ] ] ] ] 15 => array:3 [ "identificador" => "bib16" "etiqueta" => "16" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Cytokeratin 19 fragment in patients with nonmalignant respiratory diseases" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "M Nakayama" 1 => "H Sayoh" 2 => "H Ishikawa" 3 => "M Fujiwara" 4 => "H Kamma" 5 => "M Ohtsuka" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Chest" "fecha" => "2003" "volumen" => "123" "paginaInicial" => "2001" "paginaFinal" => "2006" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12796181" "web" => "Medline" ] ] ] ] ] ] ] ] 16 => array:3 [ "identificador" => "bib17" "etiqueta" => "17" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Transfer of TNF-alpha to rat lung induces severe pulmonary inflammation and patchy interstitial fibrogenesis with induction of transforming growth factor-beta 1 and myofibroblasts" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:3 [ 0 => "PJ Sime" 1 => "RA Marr" 2 => "D Gauldie" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Am J Pathol" "fecha" => "1998" "volumen" => "153" "paginaInicial" => "825" "paginaFinal" => "832" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9736031" "web" => "Medline" ] ] ] ] ] ] ] ] 17 => array:3 [ "identificador" => "bib18" "etiqueta" => "18" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Transforming growth factor β in tissue fibrosis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "W Border" 1 => "N Noble" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1056/NEJM199411103311907" "Revista" => array:6 [ "tituloSerie" => "N Engl J Med" "fecha" => "1994" "volumen" => "331" "paginaInicial" => "1286" "paginaFinal" => "1294" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7935686" "web" => "Medline" ] ] ] ] ] ] ] ] 18 => array:3 [ "identificador" => "bib19" "etiqueta" => "19" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Circulating transforming factor β. A potential marker of the disease activity during idiopathic pulmonary fibrosis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "Y Suk-Joong" 1 => "AH Adlakha" 2 => "A Limper" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Chest" "fecha" => "2001" "volumen" => "120" "paginaInicial" => "68S" "paginaFinal" => "70S" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11451931" "web" => "Medline" ] ] ] ] ] ] ] ] 19 => array:3 [ "identificador" => "bib20" "etiqueta" => "20" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Determinación en plasma del factor transformador del crecimiento β<span class="elsevierStyleInf">1</span> en la fibrosis pulmonar idiopática" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "M Molina-Molina" 1 => "S Lario" 2 => "P Luburich" 3 => "J Ramírez" 4 => "MT Carrión" 5 => "A Xaubet" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Arch Bronconeumol" "fecha" => "2006" "volumen" => "42" "paginaInicial" => "380" "paginaFinal" => "383" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16948989" "web" => "Medline" ] ] ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/15792129/0000004200000008/v1_201305150251/S1579212906605491/v1_201305150251/en/main.assets" "Apartado" => null "PDF" => "https://static.elsevier.es/multimedia/15792129/0000004200000008/v1_201305150251/S1579212906605491/v1_201305150251/en/main.pdf?idApp=UINPBA00003Z&text.app=https://archbronconeumol.org/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1579212906605491?idApp=UINPBA00003Z" ]
| Year/Month | Html | Total | |
|---|---|---|---|
| 2024 November | 5 | 3 | 8 |
| 2024 October | 29 | 18 | 47 |
| 2024 September | 27 | 14 | 41 |
| 2024 August | 42 | 35 | 77 |
| 2024 July | 33 | 22 | 55 |
| 2024 June | 37 | 35 | 72 |
| 2024 May | 37 | 38 | 75 |
| 2024 April | 19 | 22 | 41 |
| 2024 March | 26 | 19 | 45 |
| 2024 February | 19 | 20 | 39 |
| 2023 March | 4 | 7 | 11 |
| 2023 February | 16 | 20 | 36 |
| 2023 January | 20 | 37 | 57 |
| 2022 December | 24 | 36 | 60 |
| 2022 November | 21 | 30 | 51 |
| 2022 October | 31 | 49 | 80 |
| 2022 September | 19 | 24 | 43 |
| 2022 August | 19 | 40 | 59 |
| 2022 July | 27 | 48 | 75 |
| 2022 June | 16 | 34 | 50 |
| 2022 May | 16 | 45 | 61 |
| 2022 April | 23 | 40 | 63 |
| 2022 March | 23 | 56 | 79 |
| 2022 February | 18 | 45 | 63 |
| 2022 January | 18 | 39 | 57 |
| 2021 December | 22 | 48 | 70 |
| 2021 November | 20 | 58 | 78 |
| 2021 October | 28 | 53 | 81 |
| 2021 September | 16 | 47 | 63 |
| 2021 August | 16 | 33 | 49 |
| 2021 July | 16 | 32 | 48 |
| 2021 June | 20 | 42 | 62 |
| 2021 May | 15 | 33 | 48 |
| 2021 April | 50 | 108 | 158 |
| 2021 March | 24 | 26 | 50 |
| 2021 February | 19 | 25 | 44 |
| 2021 January | 17 | 16 | 33 |
| 2020 December | 13 | 20 | 33 |
| 2020 November | 17 | 28 | 45 |
| 2020 October | 9 | 23 | 32 |
| 2020 September | 6 | 18 | 24 |
| 2020 August | 15 | 27 | 42 |
| 2020 July | 13 | 26 | 39 |
| 2020 June | 9 | 12 | 21 |
| 2020 May | 25 | 20 | 45 |
| 2020 April | 43 | 21 | 64 |
| 2020 March | 40 | 16 | 56 |
| 2020 February | 63 | 17 | 80 |
| 2020 January | 53 | 26 | 79 |
| 2019 December | 39 | 21 | 60 |
| 2019 November | 20 | 18 | 38 |
| 2019 October | 12 | 11 | 23 |
| 2019 September | 5 | 15 | 20 |
| 2019 August | 14 | 11 | 25 |
| 2019 July | 14 | 20 | 34 |
| 2019 June | 5 | 8 | 13 |
| 2019 May | 13 | 28 | 41 |
| 2019 April | 10 | 35 | 45 |
| 2019 March | 12 | 28 | 40 |
| 2019 February | 15 | 25 | 40 |
| 2019 January | 8 | 18 | 26 |
| 2018 December | 5 | 30 | 35 |
| 2018 November | 16 | 27 | 43 |
| 2018 October | 14 | 20 | 34 |
| 2018 September | 9 | 10 | 19 |
| 2018 May | 4 | 2 | 6 |
| 2018 April | 5 | 8 | 13 |
| 2018 March | 6 | 10 | 16 |
| 2018 February | 3 | 7 | 10 |
| 2018 January | 2 | 7 | 9 |
| 2017 December | 10 | 16 | 26 |
| 2017 November | 1 | 20 | 21 |
| 2017 October | 6 | 24 | 30 |
| 2017 September | 3 | 15 | 18 |
| 2017 August | 6 | 23 | 29 |
| 2017 July | 4 | 24 | 28 |
| 2017 June | 20 | 22 | 42 |
| 2017 May | 7 | 22 | 29 |
| 2017 April | 2 | 28 | 30 |
| 2017 March | 2 | 13 | 15 |
| 2017 February | 1 | 9 | 10 |
| 2017 January | 1 | 8 | 9 |
| 2016 December | 6 | 7 | 13 |
| 2016 November | 16 | 11 | 27 |
| 2016 October | 13 | 20 | 33 |
| 2016 September | 9 | 13 | 22 |
| 2016 August | 9 | 4 | 13 |
| 2016 July | 10 | 5 | 15 |
| 2016 March | 1 | 0 | 1 |
| 2016 February | 2 | 0 | 2 |
| 2015 December | 3 | 0 | 3 |
| 2015 October | 46 | 7 | 53 |
| 2015 September | 53 | 5 | 58 |
| 2015 August | 36 | 14 | 50 |
| 2015 July | 48 | 6 | 54 |
| 2015 June | 33 | 4 | 37 |
| 2015 May | 36 | 6 | 42 |
| 2015 April | 36 | 8 | 44 |
| 2015 March | 37 | 7 | 44 |
| 2015 February | 38 | 5 | 43 |
| 2015 January | 29 | 3 | 32 |
| 2014 December | 29 | 4 | 33 |
| 2014 November | 38 | 5 | 43 |
| 2014 October | 68 | 9 | 77 |
| 2014 September | 44 | 5 | 49 |
| 2014 August | 40 | 9 | 49 |
| 2014 July | 31 | 6 | 37 |
| 2014 June | 50 | 8 | 58 |
| 2014 May | 41 | 9 | 50 |
| 2014 April | 40 | 9 | 49 |
| 2014 March | 46 | 8 | 54 |
| 2014 February | 58 | 6 | 64 |
| 2014 January | 24 | 5 | 29 |
| 2013 December | 23 | 11 | 34 |
| 2013 November | 17 | 7 | 24 |
| 2013 October | 37 | 9 | 46 |
| 2013 September | 31 | 10 | 41 |
| 2013 August | 37 | 7 | 44 |
| 2013 July | 44 | 12 | 56 |
| 2013 June | 42 | 13 | 55 |
| 2013 May | 33 | 4 | 37 |
| 2013 April | 25 | 4 | 29 |
| 2013 March | 8 | 2 | 10 |
Show all
