Case Report
Lung Involvement in Leptospirosis
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Fuentes, J.A. Caminero" "autores" => array:2 [ 0 => array:2 [ "nombre" => "Z.M." "apellidos" => "Fuentes" ] 1 => array:3 [ "preGrado" => "Dr." "nombre" => "J.A." "apellidos" => "Caminero" ] ] ] ] ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1579212906604424?idApp=UINPBA00003Z" "url" => "/15792129/0000004200000004/v1_201305150241/S1579212906604424/v1_201305150241/en/main.assets" ] "en" => array:14 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Case Report</span>" "titulo" => "Lung Involvement in Leptospirosis" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "202" "paginaFinal" => "204" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "E. Márquez-Martín, B. Valera-Bestard, R. Luque-Márquez, A. Alarcón-González" "autores" => array:4 [ 0 => array:3 [ "nombre" => "E." "apellidos" => "Márquez-Martín" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] ] ] 1 => array:3 [ "nombre" => "B." "apellidos" => "Valera-Bestard" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff2" ] ] ] 2 => array:4 [ "preGrado" => "Dr." "nombre" => "R." "apellidos" => "Luque-Márquez" "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor1" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff2" ] ] ] 3 => array:3 [ "nombre" => "A." "apellidos" => "Alarcón-González" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff2" ] ] ] ] "afiliaciones" => array:2 [ 0 => array:3 [ "entidad" => "Unidad Médico-Quirúrgica de Enfermedades Respiratorias, Hospital Universitario Virgen del Rocío, Sevilla, Spain" "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] 1 => array:3 [ "entidad" => "Unidad de Enfermedades Infecciosas, Hospital Universitario Virgen del Rocío, Sevilla, Spain" "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff2" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor1" "etiqueta" => "*" "correspondencia" => "Correspondence: Dr. E. Márquez-Martín. Unidad Médico-Quirúrgica de Enfermedades Respiratorias. Hospital Universitario Virgen del Rocío. Avda. Manuel Siurot, s/n. 41012 Sevilla. España" ] ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2005-06-16" "fechaAceptado" => "2005-08-30" "PalabrasClave" => array:2 [ "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key words" "identificador" => "xpalclavsec154319" "palabras" => array:3 [ 0 => "Leptospirosis" 1 => "Weil disease" 2 => "Lung disease" ] ] ] "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec154318" "palabras" => array:3 [ 0 => "Leptospirosis" 1 => "Enfermedad de Weil" 2 => "Enfermedad pulmonar" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "en" => array:1 [ "resumen" => "<p class="elsevierStyleSimplePara elsevierViewall">We reviewed a series of 5 cases of leptospirosis treated in our hospital between 1998 and 2004 and found that lung involvement was observed in 3 of the 5 cases. All patients met the criteria for the diagnosis of leptospirosis. Weil syndrome was diagnosed in 4 patients and anicteric leptospirosis in 1 patient. The 3 patients with lung sequelae were admitted into the intensive care unit because of severe respiratory failure. All patients responded to antibiotic treatment; 3 received doxycycline and 2 received doxycycline with penicillin G.</p><p class="elsevierStyleSimplePara elsevierViewall">Leptospirosis can lead to severe lung complications often requiring admission to the intensive care unit. The degree of severity is independent of the particular clinical syndrome (the anicteric form or Weil syndrome). Finally, despite the severity of the clinical picture, our patients responded to medical treatment and did not require invasive mechanical ventilation.</p>" ] "es" => array:1 [ "resumen" => "<p class="elsevierStyleSimplePara elsevierViewall">Hemos realizado una revisión retrospectiva de una serie de 5 casos de leptospirosis, en 3 de los cuales se detectó afectación pulmonar, ingresados entre 1998 y 2004 en nuestro hospital. Los 5 pacientes presentaron criterios confirmados de leptospirosis. Cuatro cumplían criterios de síndrome de Weil y el restante, de leptospirosis anictérica. Los 3 pacientes con escuelas pulmonares ingresaron en la unidad de cuidados intensivos por presentar insuficiencia respiratoria grave. Los 5 casos evolucionaron favorablemente con tratamiento antibiótico, 3 con doxiciclina y 2 con doxiciclina asociada a penicilina G.</p><p class="elsevierStyleSimplePara elsevierViewall">En conclusión, en la leptospirosis hay complicaciones pulmonares graves que requieren con frecuencia ingreso en la unidad de cuidados intensivos. El estado de gravedad es independiente del síndrome clínico variante anictérica o síndrome de Weil. Por último, a pesar de la gravedad en su forma de presentación, en nuestra experiencia la evolución es favorable con tratamiento médico, sin necesidad de ventilación mecánica invasiva.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "REFERENCES" "seccion" => array:1 [ 0 => array:1 [ "bibliografiaReferencia" => array:8 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Leptospirosis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "JM Vinet" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Curr Opin Infect Dis." 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"fecha" => "2000" "volumen" => "19" "paginaInicial" => "471" "paginaFinal" => "474" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10947225" "web" => "Medline" ] ] ] ] ] ] ] ] 5 => array:3 [ "identificador" => "bib6" "etiqueta" => "6" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Pulmonary complications of leptospirosis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "CR Carvalho" 1 => "EP Bethlem" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Clin Chest Med." 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"fecha" => "2001" "volumen" => "17" "paginaInicial" => "68" "paginaFinal" => "73" ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/15792129/0000004200000004/v1_201305150241/S1579212906604436/v1_201305150241/en/main.assets" "Apartado" => null "PDF" => "https://static.elsevier.es/multimedia/15792129/0000004200000004/v1_201305150241/S1579212906604436/v1_201305150241/en/main.pdf?idApp=UINPBA00003Z&text.app=https://archbronconeumol.org/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1579212906604436?idApp=UINPBA00003Z" ]
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