was read the article
array:23 [ "pii" => "S1579212906604242" "issn" => "15792129" "doi" => "10.1016/S1579-2129(06)60424-2" "estado" => "S300" "fechaPublicacion" => "2005-04-01" "aid" => "60424" "copyright" => "Sociedad Española de Neumología y Cirugía Torácica (SEPAR)" "copyrightAnyo" => "2005" "documento" => "article" "crossmark" => 0 "subdocumento" => "fla" "cita" => "Arch Bronconeumol. 2005;41:189-96" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 2335 "formatos" => array:3 [ "EPUB" => 90 "HTML" => 1566 "PDF" => 679 ] ] "itemSiguiente" => array:18 [ "pii" => "S1579212906604254" "issn" => "15792129" "doi" => "10.1016/S1579-2129(06)60425-4" "estado" => "S300" "fechaPublicacion" => "2005-04-01" "aid" => "60425" "copyright" => "Sociedad Española de Neumología y Cirugía Torácica (SEPAR)" "documento" => "article" "crossmark" => 0 "subdocumento" => "fla" "cita" => "Arch Bronconeumol. 2005;41:197-201" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 2064 "formatos" => array:3 [ "EPUB" => 104 "HTML" => 1336 "PDF" => 624 ] ] "en" => array:10 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Original Articles</span>" "titulo" => "Results of a Comprehensive Workplace Program for the Prevention and Treatment of Smoking Addiction" "tienePdf" => "en" "tieneTextoCompleto" => 0 "tieneResumen" => array:2 [ 0 => "en" 1 => "es" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "197" "paginaFinal" => "201" ] ] "contieneResumen" => array:2 [ "en" => true "es" => true ] "contienePdf" => array:1 [ "en" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "I. Nerín, A. Crucelaegui, A. Más, J.A. Villalba, D. Guillén, A. Gracia" "autores" => array:6 [ 0 => array:3 [ "preGrado" => "Dra" "nombre" => "I." "apellidos" => "Nerín" ] 1 => array:2 [ "nombre" => "A." "apellidos" => "Crucelaegui" ] 2 => array:2 [ "nombre" => "A." "apellidos" => "Más" ] 3 => array:2 [ "nombre" => "J.A." "apellidos" => "Villalba" ] 4 => array:2 [ "nombre" => "D." "apellidos" => "Guillén" ] 5 => array:2 [ "nombre" => "A." "apellidos" => "Gracia" ] ] ] ] ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1579212906604254?idApp=UINPBA00003Z" "url" => "/15792129/0000004100000004/v1_201305150213/S1579212906604254/v1_201305150213/en/main.assets" ] "itemAnterior" => array:18 [ "pii" => "S1579212906604230" "issn" => "15792129" "doi" => "10.1016/S1579-2129(06)60423-0" "estado" => "S300" "fechaPublicacion" => "2005-04-01" "aid" => "60423" "copyright" => "Sociedad Española de Neumología y Cirugía Torácica (SEPAR)" "documento" => "article" "crossmark" => 0 "subdocumento" => "fla" "cita" => "Arch Bronconeumol. 2005;41:185-8" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 2202 "formatos" => array:3 [ "EPUB" => 106 "HTML" => 1458 "PDF" => 638 ] ] "en" => array:10 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Original Articles</span>" "titulo" => "Prognostic Value of the Carcinoembryonic Antigen Found in Pleural Lavage Fluid From Patients With Lung Carcinoma" "tienePdf" => "en" "tieneTextoCompleto" => 0 "tieneResumen" => array:2 [ 0 => "en" 1 => "es" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "185" "paginaFinal" => "188" ] ] "contieneResumen" => array:2 [ "en" => true "es" => true ] "contienePdf" => array:1 [ "en" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "J.M. Galbis Caravajal, S. Benlloch Carrión, J. Sánchez Payá, J.J. Mafé Madueño, B. Baschwitz Gómez, J.M. Rodríguez Paniagua" "autores" => array:6 [ 0 => array:3 [ "preGrado" => "Dr." "nombre" => "J.M." "apellidos" => "Galbis Caravajal" ] 1 => array:2 [ "nombre" => "S." "apellidos" => "Benlloch Carrión" ] 2 => array:2 [ "nombre" => "J." "apellidos" => "Sánchez Payá" ] 3 => array:2 [ "nombre" => "J.J." "apellidos" => "Mafé Madueño" ] 4 => array:2 [ "nombre" => "B." "apellidos" => "Baschwitz Gómez" ] 5 => array:2 [ "nombre" => "J.M." "apellidos" => "Rodríguez Paniagua" ] ] ] ] ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1579212906604230?idApp=UINPBA00003Z" "url" => "/15792129/0000004100000004/v1_201305150213/S1579212906604230/v1_201305150213/en/main.assets" ] "en" => array:14 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Original Articles</span>" "titulo" => "Clinical and Epidemiological Study of Disease Caused by <span class="elsevierStyleItalic">Mycobacterium kansasii</span> in the Metropolitan Area of Bilbao, Spain" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "189" "paginaFinal" => "196" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "M.V. Leal Arranz, A. Gaafar, M.J. Unzaga Barañano, J.A. Crespo Notario, R. Cisterna Cáncer, F. García Cebrián" "autores" => array:6 [ 0 => array:5 [ "preGrado" => "Dra" "nombre" => "M.V." "apellidos" => "Leal Arranz" "email" => array:1 [ 0 => "mavija@euskalnet.net" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor1" ] ] ] 1 => array:3 [ "nombre" => "A." "apellidos" => "Gaafar" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff2" ] ] ] 2 => array:3 [ "nombre" => "M.J." "apellidos" => "Unzaga Barañano" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff2" ] ] ] 3 => array:3 [ "nombre" => "J.A." "apellidos" => "Crespo Notario" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] ] ] 4 => array:3 [ "nombre" => "R." "apellidos" => "Cisterna Cáncer" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff2" ] ] ] 5 => array:3 [ "nombre" => "F." "apellidos" => "García Cebrián" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] ] ] ] "afiliaciones" => array:2 [ 0 => array:3 [ "entidad" => "Servicio de Neumología, Hospital de Basurto, Bilbao, Bizkaia, Spain" "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] 1 => array:3 [ "entidad" => "Servicio de Microbiología, Hospital de Basurto, Bilbao, Bizkaia, Spain" "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff2" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor1" "etiqueta" => "*" "correspondencia" => "Correspondence: Dra. M.V. Leal Arranz. Avda. Montevideo, s/n. 48013 Bilbao. Bizkaia. España" ] ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2004-04-22" "fechaAceptado" => "2004-09-19" "PalabrasClave" => array:2 [ "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key Words" "identificador" => "xpalclavsec154022" "palabras" => array:3 [ 0 => "Epidemiology" 1 => "Human immunodeficiency virus" 2 => "M kansasii" ] ] ] "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec154023" "palabras" => array:3 [ 0 => "Epidemiología" 1 => "Virus de la inmunodeficiencia humana" 2 => "M. kansasii" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "en" => array:1 [ "resumen" => "<span class="elsevierStyleSectionTitle">Objective</span><p class="elsevierStyleSimplePara elsevierViewall">Epidemiological description of individuals from whom <span class="elsevierStyleItalic">Mycobacterium kansasii</span> isolates were obtained in respiratory samples, and analysis of the isolates using molecular biological techniques.</p> <span class="elsevierStyleSectionTitle">Material and Methods</span><p class="elsevierStyleSimplePara elsevierViewall">A descriptive retrospective/prospective study was carried out from January 1994 to April 2002 in Basurto Hospital and Santa Marina Hospital and from January 2000 to April 2002 in Cruces Hospital, Galdakao Hospital, and San Eloy Hospital. Diagnosis of the disease was performed according to American Thoracic Society criteria; other definitions were also applied to allow inclusion of all cases. Disease caused by <span class="elsevierStyleItalic">M kansasii</span> in patients who were not infected with the human immunodeficiency virus (HIV) was compared with disease caused by <span class="elsevierStyleItalic">Mycobacterium tuberculosis</span> in a control group. Polymerase chain reaction was applied with analysis of restriction fragment length polymorphisms to differentiate between species of mycobacteria and classify them into genotypes. Amplified fragment length polymorphisms were used to recognize clones within each genotype.</p> <span class="elsevierStyleSectionTitle">Results</span><p class="elsevierStyleSimplePara elsevierViewall">The patient charts of 334 patients in which an isolate of <span class="elsevierStyleItalic">M kansasii</span> had been recorded were reviewed. We considered 220 patients to be suffering from disease caused by <span class="elsevierStyleItalic">M kansasii</span> (American Thoracic Society criteria along with probable disease according to established definitions). The disease was more frequent in male patients (n=185; 84.1%) and in individuals who were not HIV positive (n=184; 83.6%). The highest incidence of disease in the Bizkaia region was found in Margen Izquierda-Encartaciones, where the rate was 8.05 per 100 000 inhabitants. In the Bilbao area, the highest rate was found in the districts lying on the outskirts. The underlying diseases were tuberculosis (20.5%), chronic obstructive pulmonary disease (25.9%), pulmonary neoplasia (7.7%), silicosis (0.9%), chronic liver disease (11.4%), and duodenal ulcer (8.6%). The most frequent constitutional symptoms were fever (39.1%), loss of appetite (23.2%), and weight loss (33.3%). Among the respiratory symptoms, the most outstanding were cough (70.9%) and expectoration (62.3%). The most frequent radiographic patterns were cavitation and pulmonary infiltration. The most common treatment regimen was rifampicin, isoniazid, and ethambutol (43.4%), and the average duration was 12 months in patients who were HIV negative. Analysis of antibiotic sensitivity, performed on 56 strains, revealed that 100% were resistant to isoniazid, while none displayed rifampicin resistance. Thirty-four cases of disease caused by <span class="elsevierStyleItalic">M kansasii</span> were compared with 68 cases of tuberculosis, all of them without HIV infection. The comparison revealed a predominance of smokers, respiratory symptoms, and cavitation in patients with disease caused by <span class="elsevierStyleItalic">M kansasii.</span> The majority of the isolates (98.5%) corresponded to genotype I. A total of 8 clones were obtained; the clones designated 1 and 3 were more common in HIV-positive and HIV-negative individuals respectively.</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p class="elsevierStyleSimplePara elsevierViewall">In recent years, there has been an increase in the number of patients with disease caused by <span class="elsevierStyleItalic">M kansasii</span> in the province of Bizkaia. The disease is more frequent in male patients, individuals who are HIV negative, and in urban areas. In addition, more respiratory symptoms and a higher incidence of cavitation were found in patients with disease caused by <span class="elsevierStyleItalic">M kansasii</span> than in those with tuberculosis. Genotype I is the most common isolate, and clones 1 and 3 affect 80% of patients suffering from the disease.</p>" ] "es" => array:1 [ "resumen" => "<span class="elsevierStyleSectionTitle">Objetivo</span><p class="elsevierStyleSimplePara elsevierViewall">Descripción epidemiológica de los individuos con aislamiento de <span class="elsevierStyleItalic">Mycobacterium kansasii</span> en muestras respiratorias y análisis de estos aislamientos mediante técnicas de biología molecular.</p> <span class="elsevierStyleSectionTitle">Material Y Métodos</span><p class="elsevierStyleSimplePara elsevierViewall">Se realizó un estudio retrospectivo, prospectivo y descriptivo de enero de 1994 a abril de 2002 en los hospitales de Basurto y Santa Marina, y de enero de 2000 a abril de 2002 en los hospitales de Cruces, Galdakao y San Eloy. Se aplicaron los criterios de la American Thoracic Society para el diagnóstico de enfermedad y se utilizaron otras definiciones para abarcar todos los casos. Se comparó la enfermedad por <span class="elsevierStyleItalic">M. kansasii</span> en pacientes sin infección por el virus de la inmunodeficiencia humana (VIH) con un grupo control con enfermedad por <span class="elsevierStyleItalic">Mycobacterium tuberculosis.</span> Se aplicó la reacción en cadena de la polimerasa con análisis de RFLP <span class="elsevierStyleItalic">(restriction fragment-length polymorphisms)</span> para diferenciar las especies de micobacterias y subtipificación en genotipos, y la AFLP <span class="elsevierStyleItalic">(amplified fragment-length polymorphisms)</span> para reconocer clones dentro de cada genotipo.</p> <span class="elsevierStyleSectionTitle">Resultados</span><p class="elsevierStyleSimplePara elsevierViewall">Se revisaron 334 historias clínicas de pacientes en los que existía un registro de aislamiento microbiológico de <span class="elsevierStyleItalic">M. kansasii.</span> Consideramos que 220 eran enfermos (criterio de la American Thoracic Society más enfermedad probable de definiciones creadas). La enfermedad era más frecuente en varones (n = 185; 84,1%) y en personas sin infección por el VIH (n = 184; 83,6%). La tasa de incidencia de enfermedad más alta en la comarca de Bizkaia fue en Margen Izquierda-Encartaciones, con un 8,05 por cada 100.000 habitantes, y en el Área de Bilbao, en los distritos de la periferia. Las enfermedades de base fueron: tuberculosis (20,5%), enfermedad pulmonar obstructiva crónica (25,9%), neoplasia de pulmón (7,7%), silicosis (0,9%), hepatopatía crónica (11,4%) y gastrectomía (8,6%). Los síntomas consti-tucionales más frecuentes fueron: fiebre (39,1%), anorexia (23,2%) y disminución de peso (33,3%). Entre los síntomas respiratorios destacaron la tos (70,9%) y la expectoración (62,3%). Los patrones radiológicos más frecuentes fueron cavitación e infiltrados pulmonares. La pauta de tratamiento más habitual fue rifampicina, isoniacida y etambutol (43,4%), y el tiempo medio de duración fue de 12 meses en las personas sin infección por el VIH. En el estudio de sensibilidad realizado en 56 cepas, el 100% fue resistente a isoniacida y ninguna mostró resistencia a rifampicina. Se compararon 34 casos de enfermedad por <span class="elsevierStyleItalic">M. kansasii</span> con 68 casos de tuberculosis, todos sin infección por el VIH, y se obtuvieron los siguientes resultados: predominio de fumadores, de síntomas respiratorios y de cavitación en los pacientes con enfermedad por <span class="elsevierStyleItalic">M. kansasii.</span> El 98,5% de los aislamientos pertenecieron al genotipo I. Se obtuvieron un total de 8 clones; el clon denominado 1 fue más frecuente en personas con infección por el VIH y el denominado 3 en los que no la presentaban.</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p class="elsevierStyleSimplePara elsevierViewall">Se ha registrado un aumento del número de pacientes con enfermedad por <span class="elsevierStyleItalic">M. kansasii</span> en la provincia de Bizkaia en los últimos años. Dicha enfermedad es más frecuente en varones, personas sin infección por el VIH y zonas urbanas. Asimismo, se han encontrado más síntomas respiratorios como manifestaciones clínicas y mayor presencia de cavitación como hallazgo radiológico en la enfermedad por <span class="elsevierStyleItalic">M. kansasii</span> al compararla con la tuberculosis. El genotipo I es el aislado con más frecuencia, y los clones 1 y 3 afectan al 80% de los individuos enfermos.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "REFERENCES" "seccion" => array:1 [ 0 => array:1 [ "bibliografiaReferencia" => array:32 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Mycobacteria in water" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "CH Collins" 1 => "JM Grange" 2 => "MD Yates" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "J Applied Bacteriology" "fecha" => "1984" "volumen" => "57" "paginaInicial" => "193" "paginaFinal" => "211" ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib2" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Endemic incidence of infections caused by <span class="elsevierStyleItalic">Mycobacterium kansasii</span> in the Karviná District in 1968-1995" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "S Chobot" 1 => "J Maliys" 2 => "H Sebyakovya" 3 => "M Pelikyan" 4 => "O Zatloukal" 5 => "P Paliycka" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Centr Eur J Publ Health" "fecha" => "1997" "volumen" => "4" "paginaInicial" => "164" "paginaFinal" => "173" ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib3" "etiqueta" => "3" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Water as a possible factor of transmission in mycobacterial infections" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "M Slosárek" 1 => "M Kubín" 2 => "J Pokorny" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Centr Eur J Publ Health" "fecha" => "1994" "volumen" => "2" "paginaInicial" => "103" "paginaFinal" => "105" "itemHostRev" => array:3 [ "pii" => "S016882780900364X" "estado" => "S300" "issn" => "01688278" ] ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib4" "etiqueta" => "4" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "High-catalase strains of <span class="elsevierStyleItalic">Mycobacterium kansasii</span> isolated from water in Texas" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "JE Steadham" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Clin Microbiol." 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Year/Month | Html | Total | |
---|---|---|---|
2024 November | 3 | 2 | 5 |
2024 October | 30 | 17 | 47 |
2024 September | 31 | 12 | 43 |
2024 August | 39 | 33 | 72 |
2024 July | 34 | 17 | 51 |
2024 June | 31 | 20 | 51 |
2024 May | 36 | 29 | 65 |
2024 April | 19 | 21 | 40 |
2024 March | 16 | 13 | 29 |
2024 February | 19 | 25 | 44 |
2023 March | 2 | 3 | 5 |
2023 February | 20 | 15 | 35 |
2023 January | 16 | 34 | 50 |
2022 December | 19 | 20 | 39 |
2022 November | 22 | 24 | 46 |
2022 October | 21 | 38 | 59 |
2022 September | 20 | 22 | 42 |
2022 August | 24 | 34 | 58 |
2022 July | 40 | 46 | 86 |
2022 June | 19 | 35 | 54 |
2022 May | 39 | 35 | 74 |
2022 April | 18 | 29 | 47 |
2022 March | 15 | 39 | 54 |
2022 February | 15 | 30 | 45 |
2022 January | 16 | 38 | 54 |
2021 December | 17 | 31 | 48 |
2021 November | 16 | 40 | 56 |
2021 October | 20 | 45 | 65 |
2021 September | 18 | 51 | 69 |
2021 August | 14 | 35 | 49 |
2021 July | 12 | 34 | 46 |
2021 June | 19 | 40 | 59 |
2021 May | 14 | 26 | 40 |
2021 April | 31 | 65 | 96 |
2021 March | 23 | 42 | 65 |
2021 February | 16 | 26 | 42 |
2021 January | 11 | 17 | 28 |
2020 December | 9 | 19 | 28 |
2020 November | 9 | 20 | 29 |
2020 October | 9 | 11 | 20 |
2020 September | 9 | 7 | 16 |
2020 August | 11 | 14 | 25 |
2020 July | 10 | 21 | 31 |
2020 June | 9 | 13 | 22 |
2020 May | 24 | 20 | 44 |
2020 April | 12 | 13 | 25 |
2020 March | 17 | 17 | 34 |
2020 February | 16 | 21 | 37 |
2020 January | 24 | 20 | 44 |
2019 December | 15 | 14 | 29 |
2019 November | 10 | 15 | 25 |
2019 October | 9 | 14 | 23 |
2019 September | 16 | 12 | 28 |
2019 August | 8 | 10 | 18 |
2019 July | 8 | 13 | 21 |
2019 June | 10 | 15 | 25 |
2019 May | 19 | 13 | 32 |
2019 April | 17 | 40 | 57 |
2019 March | 19 | 20 | 39 |
2019 February | 4 | 12 | 16 |
2019 January | 7 | 7 | 14 |
2018 December | 11 | 16 | 27 |
2018 November | 13 | 11 | 24 |
2018 October | 17 | 22 | 39 |
2018 September | 4 | 11 | 15 |
2018 May | 3 | 0 | 3 |
2018 April | 6 | 8 | 14 |
2018 March | 2 | 1 | 3 |
2018 February | 5 | 9 | 14 |
2018 January | 3 | 7 | 10 |
2017 December | 3 | 6 | 9 |
2017 November | 3 | 8 | 11 |
2017 October | 7 | 7 | 14 |
2017 September | 2 | 8 | 10 |
2017 August | 7 | 16 | 23 |
2017 July | 4 | 6 | 10 |
2017 June | 5 | 10 | 15 |
2017 May | 6 | 9 | 15 |
2017 April | 2 | 1 | 3 |
2017 March | 3 | 5 | 8 |
2017 February | 3 | 4 | 7 |
2017 January | 4 | 11 | 15 |
2016 December | 9 | 6 | 15 |
2016 November | 12 | 5 | 17 |
2016 October | 19 | 10 | 29 |
2016 September | 19 | 13 | 32 |
2016 August | 14 | 5 | 19 |
2016 July | 5 | 4 | 9 |
2016 March | 2 | 0 | 2 |
2015 December | 2 | 0 | 2 |
2015 October | 47 | 1 | 48 |
2015 September | 33 | 17 | 50 |
2015 August | 46 | 9 | 55 |
2015 July | 35 | 6 | 41 |
2015 June | 42 | 9 | 51 |
2015 May | 36 | 9 | 45 |
2015 April | 36 | 12 | 48 |
2015 March | 33 | 9 | 42 |
2015 February | 30 | 1 | 31 |
2015 January | 26 | 8 | 34 |
2014 December | 31 | 6 | 37 |
2014 November | 36 | 5 | 41 |
2014 October | 33 | 7 | 40 |
2014 September | 28 | 7 | 35 |
2014 August | 35 | 10 | 45 |
2014 July | 38 | 7 | 45 |
2014 June | 51 | 11 | 62 |
2014 May | 52 | 12 | 64 |
2014 April | 46 | 6 | 52 |
2014 March | 52 | 7 | 59 |
2014 February | 62 | 6 | 68 |
2014 January | 41 | 7 | 48 |
2013 December | 31 | 5 | 36 |
2013 November | 36 | 9 | 45 |
2013 October | 47 | 6 | 53 |
2013 September | 38 | 9 | 47 |
2013 August | 37 | 7 | 44 |
2013 July | 46 | 14 | 60 |
2013 June | 38 | 10 | 48 |
2013 May | 34 | 5 | 39 |
2013 April | 15 | 5 | 20 |
2013 March | 6 | 2 | 8 |