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        "resumen" => "<span class="elsevierStyleSectionTitle">Objective</span><p class="elsevierStyleSimplePara elsevierViewall">Epidemiological description of individuals from whom <span class="elsevierStyleItalic">Mycobacterium kansasii</span> isolates were obtained in respiratory samples&#44; and analysis of the isolates using molecular biological techniques&#46;</p> <span class="elsevierStyleSectionTitle">Material and Methods</span><p class="elsevierStyleSimplePara elsevierViewall">A descriptive retrospective&#47;prospective study was carried out from January 1994 to April 2002 in Basurto Hospital and Santa Marina Hospital and from January 2000 to April 2002 in Cruces Hospital&#44; Galdakao Hospital&#44; and San Eloy Hospital&#46; Diagnosis of the disease was performed according to American Thoracic Society criteria&#59; other definitions were also applied to allow inclusion of all cases&#46; Disease caused by <span class="elsevierStyleItalic">M kansasii</span> in patients who were not infected with the human immunodeficiency virus &#40;HIV&#41; was compared with disease caused by <span class="elsevierStyleItalic">Mycobacterium tuberculosis</span> in a control group&#46; Polymerase chain reaction was applied with analysis of restriction fragment length polymorphisms to differentiate between species of mycobacteria and classify them into genotypes&#46; Amplified fragment length polymorphisms were used to recognize clones within each genotype&#46;</p> <span class="elsevierStyleSectionTitle">Results</span><p class="elsevierStyleSimplePara elsevierViewall">The patient charts of 334 patients in which an isolate of <span class="elsevierStyleItalic">M kansasii</span> had been recorded were reviewed&#46; We considered 220 patients to be suffering from disease caused by <span class="elsevierStyleItalic">M kansasii</span> &#40;American Thoracic Society criteria along with probable disease according to established definitions&#41;&#46; The disease was more frequent in male patients &#40;n&#61;185&#59; 84&#46;1&#37;&#41; and in individuals who were not HIV positive &#40;n&#61;184&#59; 83&#46;6&#37;&#41;&#46; The highest incidence of disease in the Bizkaia region was found in Margen Izquierda-Encartaciones&#44; where the rate was 8&#46;05 per 100&#8200;000 inhabitants&#46; In the Bilbao area&#44; the highest rate was found in the districts lying on the outskirts&#46; The underlying diseases were tuberculosis &#40;20&#46;5&#37;&#41;&#44; chronic obstructive pulmonary disease &#40;25&#46;9&#37;&#41;&#44; pulmonary neoplasia &#40;7&#46;7&#37;&#41;&#44; silicosis &#40;0&#46;9&#37;&#41;&#44; chronic liver disease &#40;11&#46;4&#37;&#41;&#44; and duodenal ulcer &#40;8&#46;6&#37;&#41;&#46; The most frequent constitutional symptoms were fever &#40;39&#46;1&#37;&#41;&#44; loss of appetite &#40;23&#46;2&#37;&#41;&#44; and weight loss &#40;33&#46;3&#37;&#41;&#46; Among the respiratory symptoms&#44; the most outstanding were cough &#40;70&#46;9&#37;&#41; and expectoration &#40;62&#46;3&#37;&#41;&#46; The most frequent radiographic patterns were cavitation and pulmonary infiltration&#46; The most common treatment regimen was rifampicin&#44; isoniazid&#44; and ethambutol &#40;43&#46;4&#37;&#41;&#44; and the average duration was 12 months in patients who were HIV negative&#46; Analysis of antibiotic sensitivity&#44; performed on 56 strains&#44; revealed that 100&#37; were resistant to isoniazid&#44; while none displayed rifampicin resistance&#46; Thirty-four cases of disease caused by <span class="elsevierStyleItalic">M kansasii</span> were compared with 68 cases of tuberculosis&#44; all of them without HIV infection&#46; The comparison revealed a predominance of smokers&#44; respiratory symptoms&#44; and cavitation in patients with disease caused by <span class="elsevierStyleItalic">M kansasii&#46;</span> The majority of the isolates &#40;98&#46;5&#37;&#41; corresponded to genotype I&#46; A total of 8 clones were obtained&#59; the clones designated 1 and 3 were more common in HIV-positive and HIV-negative individuals respectively&#46;</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p class="elsevierStyleSimplePara elsevierViewall">In recent years&#44; there has been an increase in the number of patients with disease caused by <span class="elsevierStyleItalic">M kansasii</span> in the province of Bizkaia&#46; The disease is more frequent in male patients&#44; individuals who are HIV negative&#44; and in urban areas&#46; In addition&#44; more respiratory symptoms and a higher incidence of cavitation were found in patients with disease caused by <span class="elsevierStyleItalic">M kansasii</span> than in those with tuberculosis&#46; Genotype I is the most common isolate&#44; and clones 1 and 3 affect 80&#37; of patients suffering from the disease&#46;</p>"
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        "resumen" => "<span class="elsevierStyleSectionTitle">Objetivo</span><p class="elsevierStyleSimplePara elsevierViewall">Descripci&#243;n epidemiol&#243;gica de los individuos con aislamiento de <span class="elsevierStyleItalic">Mycobacterium kansasii</span> en muestras respiratorias y an&#225;lisis de estos aislamientos mediante t&#233;cnicas de biolog&#237;a molecular&#46;</p> <span class="elsevierStyleSectionTitle">Material Y M&#233;todos</span><p class="elsevierStyleSimplePara elsevierViewall">Se realiz&#243; un estudio retrospectivo&#44; prospectivo y descriptivo de enero de 1994 a abril de 2002 en los hospitales de Basurto y Santa Marina&#44; y de enero de 2000 a abril de 2002 en los hospitales de Cruces&#44; Galdakao y San Eloy&#46; Se aplicaron los criterios de la American Thoracic Society para el diagn&#243;stico de enfermedad y se utilizaron otras definiciones para abarcar todos los casos&#46; Se compar&#243; la enfermedad por <span class="elsevierStyleItalic">M&#46; kansasii</span> en pacientes sin infecci&#243;n por el virus de la inmunodeficiencia humana &#40;VIH&#41; con un grupo control con enfermedad por <span class="elsevierStyleItalic">Mycobacterium tuberculosis&#46;</span> Se aplic&#243; la reacci&#243;n en cadena de la polimerasa con an&#225;lisis de RFLP <span class="elsevierStyleItalic">&#40;restriction fragment-length polymorphisms&#41;</span> para diferenciar las especies de micobacterias y subtipificaci&#243;n en genotipos&#44; y la AFLP <span class="elsevierStyleItalic">&#40;amplified fragment-length polymorphisms&#41;</span> para reconocer clones dentro de cada genotipo&#46;</p> <span class="elsevierStyleSectionTitle">Resultados</span><p class="elsevierStyleSimplePara elsevierViewall">Se revisaron 334 historias cl&#237;nicas de pacientes en los que exist&#237;a un registro de aislamiento microbiol&#243;gico de <span class="elsevierStyleItalic">M&#46; kansasii&#46;</span> Consideramos que 220 eran enfermos &#40;criterio de la American Thoracic Society m&#225;s enfermedad probable de definiciones creadas&#41;&#46; La enfermedad era m&#225;s frecuente en varones &#40;n &#61; 185&#59; 84&#44;1&#37;&#41; y en personas sin infecci&#243;n por el VIH &#40;n &#61; 184&#59; 83&#44;6&#37;&#41;&#46; La tasa de incidencia de enfermedad m&#225;s alta en la comarca de Bizkaia fue en Margen Izquierda-Encartaciones&#44; con un 8&#44;05 por cada 100&#46;000 habitantes&#44; y en el &#193;rea de Bilbao&#44; en los distritos de la periferia&#46; Las enfermedades de base fueron&#58; tuberculosis &#40;20&#44;5&#37;&#41;&#44; enfermedad pulmonar obstructiva cr&#243;nica &#40;25&#44;9&#37;&#41;&#44; neoplasia de pulm&#243;n &#40;7&#44;7&#37;&#41;&#44; silicosis &#40;0&#44;9&#37;&#41;&#44; hepatopat&#237;a cr&#243;nica &#40;11&#44;4&#37;&#41; y gastrectom&#237;a &#40;8&#44;6&#37;&#41;&#46; Los s&#237;ntomas consti-tucionales m&#225;s frecuentes fueron&#58; fiebre &#40;39&#44;1&#37;&#41;&#44; anorexia &#40;23&#44;2&#37;&#41; y disminuci&#243;n de peso &#40;33&#44;3&#37;&#41;&#46; Entre los s&#237;ntomas respiratorios destacaron la tos &#40;70&#44;9&#37;&#41; y la expectoraci&#243;n &#40;62&#44;3&#37;&#41;&#46; Los patrones radiol&#243;gicos m&#225;s frecuentes fueron cavitaci&#243;n e infiltrados pulmonares&#46; La pauta de tratamiento m&#225;s habitual fue rifampicina&#44; isoniacida y etambutol &#40;43&#44;4&#37;&#41;&#44; y el tiempo medio de duraci&#243;n fue de 12 meses en las personas sin infecci&#243;n por el VIH&#46; En el estudio de sensibilidad realizado en 56 cepas&#44; el 100&#37; fue resistente a isoniacida y ninguna mostr&#243; resistencia a rifampicina&#46; Se compararon 34 casos de enfermedad por <span class="elsevierStyleItalic">M&#46; kansasii</span> con 68 casos de tuberculosis&#44; todos sin infecci&#243;n por el VIH&#44; y se obtuvieron los siguientes resultados&#58; predominio de fumadores&#44; de s&#237;ntomas respiratorios y de cavitaci&#243;n en los pacientes con enfermedad por <span class="elsevierStyleItalic">M&#46; kansasii&#46;</span> El 98&#44;5&#37; de los aislamientos pertenecieron al genotipo I&#46; Se obtuvieron un total de 8 clones&#59; el clon denominado 1 fue m&#225;s frecuente en personas con infecci&#243;n por el VIH y el denominado 3 en los que no la presentaban&#46;</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p class="elsevierStyleSimplePara elsevierViewall">Se ha registrado un aumento del n&#250;mero de pacientes con enfermedad por <span class="elsevierStyleItalic">M&#46; kansasii</span> en la provincia de Bizkaia en los &#250;ltimos a&#241;os&#46; Dicha enfermedad es m&#225;s frecuente en varones&#44; personas sin infecci&#243;n por el VIH y zonas urbanas&#46; Asimismo&#44; se han encontrado m&#225;s s&#237;ntomas respiratorios como manifestaciones cl&#237;nicas y mayor presencia de cavitaci&#243;n como hallazgo radiol&#243;gico en la enfermedad por <span class="elsevierStyleItalic">M&#46; kansasii</span> al compararla con la tuberculosis&#46; El genotipo I es el aislado con m&#225;s frecuencia&#44; y los clones 1 y 3 afectan al 80&#37; de los individuos enfermos&#46;</p>"
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Original Articles
Clinical and Epidemiological Study of Disease Caused by Mycobacterium kansasii in the Metropolitan Area of Bilbao, Spain
M.V. Leal Arranza,
Corresponding author
mavija@euskalnet.net

Correspondence: Dra. M.V. Leal Arranz. Avda. Montevideo, s/n. 48013 Bilbao. Bizkaia. España
, A. Gaafarb, M.J. Unzaga Barañanob, J.A. Crespo Notarioa, R. Cisterna Cáncerb, F. García Cebriána
a Servicio de Neumología, Hospital de Basurto, Bilbao, Bizkaia, Spain
b Servicio de Microbiología, Hospital de Basurto, Bilbao, Bizkaia, Spain
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            0 => "Epidemiology"
            1 => "Human immunodeficiency virus"
            2 => "M kansasii"
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          "palabras" => array:3 [
            0 => "Epidemiolog&#237;a"
            1 => "Virus de la inmunodeficiencia humana"
            2 => "M&#46; kansasii"
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        "resumen" => "<span class="elsevierStyleSectionTitle">Objective</span><p class="elsevierStyleSimplePara elsevierViewall">Epidemiological description of individuals from whom <span class="elsevierStyleItalic">Mycobacterium kansasii</span> isolates were obtained in respiratory samples&#44; and analysis of the isolates using molecular biological techniques&#46;</p> <span class="elsevierStyleSectionTitle">Material and Methods</span><p class="elsevierStyleSimplePara elsevierViewall">A descriptive retrospective&#47;prospective study was carried out from January 1994 to April 2002 in Basurto Hospital and Santa Marina Hospital and from January 2000 to April 2002 in Cruces Hospital&#44; Galdakao Hospital&#44; and San Eloy Hospital&#46; Diagnosis of the disease was performed according to American Thoracic Society criteria&#59; other definitions were also applied to allow inclusion of all cases&#46; Disease caused by <span class="elsevierStyleItalic">M kansasii</span> in patients who were not infected with the human immunodeficiency virus &#40;HIV&#41; was compared with disease caused by <span class="elsevierStyleItalic">Mycobacterium tuberculosis</span> in a control group&#46; Polymerase chain reaction was applied with analysis of restriction fragment length polymorphisms to differentiate between species of mycobacteria and classify them into genotypes&#46; Amplified fragment length polymorphisms were used to recognize clones within each genotype&#46;</p> <span class="elsevierStyleSectionTitle">Results</span><p class="elsevierStyleSimplePara elsevierViewall">The patient charts of 334 patients in which an isolate of <span class="elsevierStyleItalic">M kansasii</span> had been recorded were reviewed&#46; We considered 220 patients to be suffering from disease caused by <span class="elsevierStyleItalic">M kansasii</span> &#40;American Thoracic Society criteria along with probable disease according to established definitions&#41;&#46; The disease was more frequent in male patients &#40;n&#61;185&#59; 84&#46;1&#37;&#41; and in individuals who were not HIV positive &#40;n&#61;184&#59; 83&#46;6&#37;&#41;&#46; The highest incidence of disease in the Bizkaia region was found in Margen Izquierda-Encartaciones&#44; where the rate was 8&#46;05 per 100&#8200;000 inhabitants&#46; In the Bilbao area&#44; the highest rate was found in the districts lying on the outskirts&#46; The underlying diseases were tuberculosis &#40;20&#46;5&#37;&#41;&#44; chronic obstructive pulmonary disease &#40;25&#46;9&#37;&#41;&#44; pulmonary neoplasia &#40;7&#46;7&#37;&#41;&#44; silicosis &#40;0&#46;9&#37;&#41;&#44; chronic liver disease &#40;11&#46;4&#37;&#41;&#44; and duodenal ulcer &#40;8&#46;6&#37;&#41;&#46; The most frequent constitutional symptoms were fever &#40;39&#46;1&#37;&#41;&#44; loss of appetite &#40;23&#46;2&#37;&#41;&#44; and weight loss &#40;33&#46;3&#37;&#41;&#46; Among the respiratory symptoms&#44; the most outstanding were cough &#40;70&#46;9&#37;&#41; and expectoration &#40;62&#46;3&#37;&#41;&#46; The most frequent radiographic patterns were cavitation and pulmonary infiltration&#46; The most common treatment regimen was rifampicin&#44; isoniazid&#44; and ethambutol &#40;43&#46;4&#37;&#41;&#44; and the average duration was 12 months in patients who were HIV negative&#46; Analysis of antibiotic sensitivity&#44; performed on 56 strains&#44; revealed that 100&#37; were resistant to isoniazid&#44; while none displayed rifampicin resistance&#46; Thirty-four cases of disease caused by <span class="elsevierStyleItalic">M kansasii</span> were compared with 68 cases of tuberculosis&#44; all of them without HIV infection&#46; The comparison revealed a predominance of smokers&#44; respiratory symptoms&#44; and cavitation in patients with disease caused by <span class="elsevierStyleItalic">M kansasii&#46;</span> The majority of the isolates &#40;98&#46;5&#37;&#41; corresponded to genotype I&#46; A total of 8 clones were obtained&#59; the clones designated 1 and 3 were more common in HIV-positive and HIV-negative individuals respectively&#46;</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p class="elsevierStyleSimplePara elsevierViewall">In recent years&#44; there has been an increase in the number of patients with disease caused by <span class="elsevierStyleItalic">M kansasii</span> in the province of Bizkaia&#46; The disease is more frequent in male patients&#44; individuals who are HIV negative&#44; and in urban areas&#46; In addition&#44; more respiratory symptoms and a higher incidence of cavitation were found in patients with disease caused by <span class="elsevierStyleItalic">M kansasii</span> than in those with tuberculosis&#46; Genotype I is the most common isolate&#44; and clones 1 and 3 affect 80&#37; of patients suffering from the disease&#46;</p>"
      ]
      "es" => array:1 [
        "resumen" => "<span class="elsevierStyleSectionTitle">Objetivo</span><p class="elsevierStyleSimplePara elsevierViewall">Descripci&#243;n epidemiol&#243;gica de los individuos con aislamiento de <span class="elsevierStyleItalic">Mycobacterium kansasii</span> en muestras respiratorias y an&#225;lisis de estos aislamientos mediante t&#233;cnicas de biolog&#237;a molecular&#46;</p> <span class="elsevierStyleSectionTitle">Material Y M&#233;todos</span><p class="elsevierStyleSimplePara elsevierViewall">Se realiz&#243; un estudio retrospectivo&#44; prospectivo y descriptivo de enero de 1994 a abril de 2002 en los hospitales de Basurto y Santa Marina&#44; y de enero de 2000 a abril de 2002 en los hospitales de Cruces&#44; Galdakao y San Eloy&#46; Se aplicaron los criterios de la American Thoracic Society para el diagn&#243;stico de enfermedad y se utilizaron otras definiciones para abarcar todos los casos&#46; Se compar&#243; la enfermedad por <span class="elsevierStyleItalic">M&#46; kansasii</span> en pacientes sin infecci&#243;n por el virus de la inmunodeficiencia humana &#40;VIH&#41; con un grupo control con enfermedad por <span class="elsevierStyleItalic">Mycobacterium tuberculosis&#46;</span> Se aplic&#243; la reacci&#243;n en cadena de la polimerasa con an&#225;lisis de RFLP <span class="elsevierStyleItalic">&#40;restriction fragment-length polymorphisms&#41;</span> para diferenciar las especies de micobacterias y subtipificaci&#243;n en genotipos&#44; y la AFLP <span class="elsevierStyleItalic">&#40;amplified fragment-length polymorphisms&#41;</span> para reconocer clones dentro de cada genotipo&#46;</p> <span class="elsevierStyleSectionTitle">Resultados</span><p class="elsevierStyleSimplePara elsevierViewall">Se revisaron 334 historias cl&#237;nicas de pacientes en los que exist&#237;a un registro de aislamiento microbiol&#243;gico de <span class="elsevierStyleItalic">M&#46; kansasii&#46;</span> Consideramos que 220 eran enfermos &#40;criterio de la American Thoracic Society m&#225;s enfermedad probable de definiciones creadas&#41;&#46; La enfermedad era m&#225;s frecuente en varones &#40;n &#61; 185&#59; 84&#44;1&#37;&#41; y en personas sin infecci&#243;n por el VIH &#40;n &#61; 184&#59; 83&#44;6&#37;&#41;&#46; La tasa de incidencia de enfermedad m&#225;s alta en la comarca de Bizkaia fue en Margen Izquierda-Encartaciones&#44; con un 8&#44;05 por cada 100&#46;000 habitantes&#44; y en el &#193;rea de Bilbao&#44; en los distritos de la periferia&#46; Las enfermedades de base fueron&#58; tuberculosis &#40;20&#44;5&#37;&#41;&#44; enfermedad pulmonar obstructiva cr&#243;nica &#40;25&#44;9&#37;&#41;&#44; neoplasia de pulm&#243;n &#40;7&#44;7&#37;&#41;&#44; silicosis &#40;0&#44;9&#37;&#41;&#44; hepatopat&#237;a cr&#243;nica &#40;11&#44;4&#37;&#41; y gastrectom&#237;a &#40;8&#44;6&#37;&#41;&#46; Los s&#237;ntomas consti-tucionales m&#225;s frecuentes fueron&#58; fiebre &#40;39&#44;1&#37;&#41;&#44; anorexia &#40;23&#44;2&#37;&#41; y disminuci&#243;n de peso &#40;33&#44;3&#37;&#41;&#46; Entre los s&#237;ntomas respiratorios destacaron la tos &#40;70&#44;9&#37;&#41; y la expectoraci&#243;n &#40;62&#44;3&#37;&#41;&#46; Los patrones radiol&#243;gicos m&#225;s frecuentes fueron cavitaci&#243;n e infiltrados pulmonares&#46; La pauta de tratamiento m&#225;s habitual fue rifampicina&#44; isoniacida y etambutol &#40;43&#44;4&#37;&#41;&#44; y el tiempo medio de duraci&#243;n fue de 12 meses en las personas sin infecci&#243;n por el VIH&#46; En el estudio de sensibilidad realizado en 56 cepas&#44; el 100&#37; fue resistente a isoniacida y ninguna mostr&#243; resistencia a rifampicina&#46; Se compararon 34 casos de enfermedad por <span class="elsevierStyleItalic">M&#46; kansasii</span> con 68 casos de tuberculosis&#44; todos sin infecci&#243;n por el VIH&#44; y se obtuvieron los siguientes resultados&#58; predominio de fumadores&#44; de s&#237;ntomas respiratorios y de cavitaci&#243;n en los pacientes con enfermedad por <span class="elsevierStyleItalic">M&#46; kansasii&#46;</span> El 98&#44;5&#37; de los aislamientos pertenecieron al genotipo I&#46; Se obtuvieron un total de 8 clones&#59; el clon denominado 1 fue m&#225;s frecuente en personas con infecci&#243;n por el VIH y el denominado 3 en los que no la presentaban&#46;</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p class="elsevierStyleSimplePara elsevierViewall">Se ha registrado un aumento del n&#250;mero de pacientes con enfermedad por <span class="elsevierStyleItalic">M&#46; kansasii</span> en la provincia de Bizkaia en los &#250;ltimos a&#241;os&#46; Dicha enfermedad es m&#225;s frecuente en varones&#44; personas sin infecci&#243;n por el VIH y zonas urbanas&#46; Asimismo&#44; se han encontrado m&#225;s s&#237;ntomas respiratorios como manifestaciones cl&#237;nicas y mayor presencia de cavitaci&#243;n como hallazgo radiol&#243;gico en la enfermedad por <span class="elsevierStyleItalic">M&#46; kansasii</span> al compararla con la tuberculosis&#46; El genotipo I es el aislado con m&#225;s frecuencia&#44; y los clones 1 y 3 afectan al 80&#37; de los individuos enfermos&#46;</p>"
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                            1 => "R Hogers"
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Article information
ISSN: 15792129
Original language: English
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2022 May 39 35 74
2022 April 18 29 47
2022 March 15 39 54
2022 February 15 30 45
2022 January 16 38 54
2021 December 17 31 48
2021 November 16 40 56
2021 October 20 45 65
2021 September 18 51 69
2021 August 14 35 49
2021 July 12 34 46
2021 June 19 40 59
2021 May 14 26 40
2021 April 31 65 96
2021 March 23 42 65
2021 February 16 26 42
2021 January 11 17 28
2020 December 9 19 28
2020 November 9 20 29
2020 October 9 11 20
2020 September 9 7 16
2020 August 11 14 25
2020 July 10 21 31
2020 June 9 13 22
2020 May 24 20 44
2020 April 12 13 25
2020 March 17 17 34
2020 February 16 21 37
2020 January 24 20 44
2019 December 15 14 29
2019 November 10 15 25
2019 October 9 14 23
2019 September 16 12 28
2019 August 8 10 18
2019 July 8 13 21
2019 June 10 15 25
2019 May 19 13 32
2019 April 17 40 57
2019 March 19 20 39
2019 February 4 12 16
2019 January 7 7 14
2018 December 11 16 27
2018 November 13 11 24
2018 October 17 22 39
2018 September 4 11 15
2018 May 3 0 3
2018 April 6 8 14
2018 March 2 1 3
2018 February 5 9 14
2018 January 3 7 10
2017 December 3 6 9
2017 November 3 8 11
2017 October 7 7 14
2017 September 2 8 10
2017 August 7 16 23
2017 July 4 6 10
2017 June 5 10 15
2017 May 6 9 15
2017 April 2 1 3
2017 March 3 5 8
2017 February 3 4 7
2017 January 4 11 15
2016 December 9 6 15
2016 November 12 5 17
2016 October 19 10 29
2016 September 19 13 32
2016 August 14 5 19
2016 July 5 4 9
2016 March 2 0 2
2015 December 2 0 2
2015 October 47 1 48
2015 September 33 17 50
2015 August 46 9 55
2015 July 35 6 41
2015 June 42 9 51
2015 May 36 9 45
2015 April 36 12 48
2015 March 33 9 42
2015 February 30 1 31
2015 January 26 8 34
2014 December 31 6 37
2014 November 36 5 41
2014 October 33 7 40
2014 September 28 7 35
2014 August 35 10 45
2014 July 38 7 45
2014 June 51 11 62
2014 May 52 12 64
2014 April 46 6 52
2014 March 52 7 59
2014 February 62 6 68
2014 January 41 7 48
2013 December 31 5 36
2013 November 36 9 45
2013 October 47 6 53
2013 September 38 9 47
2013 August 37 7 44
2013 July 46 14 60
2013 June 38 10 48
2013 May 34 5 39
2013 April 15 5 20
2013 March 6 2 8
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