Case Reports
Small Cell Lung Cancer and Cancer-Associated Retinopathy
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Vennera, C. Picado" "autores" => array:2 [ 0 => array:3 [ "preGrado" => "Dra" "nombre" => "M.C." "apellidos" => "Vennera" ] 1 => array:2 [ "nombre" => "C." "apellidos" => "Picado" ] ] ] ] ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1579212906604047?idApp=UINPBA00003Z" "url" => "/15792129/0000004100000002/v1_201305150204/S1579212906604047/v1_201305150204/en/main.assets" ] "en" => array:14 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Case Reports</span>" "titulo" => "Small Cell Lung Cancer and Cancer-Associated Retinopathy" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "99" "paginaFinal" => "101" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "C. Bidegain, J. Rigalt, E. Ribot, J. Dorca, J. Vayreda" "autores" => array:5 [ 0 => array:4 [ "nombre" => "C." "apellidos" => "Bidegain" "email" => array:1 [ 0 => "cbidegain@comg.es" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor1" ] ] ] 1 => array:3 [ "nombre" => "J." "apellidos" => "Rigalt" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff2" ] ] ] 2 => array:3 [ "nombre" => "E." "apellidos" => "Ribot" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">c</span>" "identificador" => "aff3" ] ] ] 3 => array:3 [ "nombre" => "J." "apellidos" => "Dorca" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">d</span>" "identificador" => "aff4" ] ] ] 4 => array:3 [ "nombre" => "J." "apellidos" => "Vayreda" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">d</span>" "identificador" => "aff4" ] ] ] ] "afiliaciones" => array:4 [ 0 => array:3 [ "entidad" => "Servicio de Cirugía Torácica, Clínica Girona, Girona, Spain" "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] 1 => array:3 [ "entidad" => "Servicio de Oftalmología, Clínica Girona, Girona, Spain" "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff2" ] 2 => array:3 [ "entidad" => "Servicio de Medicina Interna, Clínica Girona, Girona, Spain" "etiqueta" => "<span class="elsevierStyleSup">c</span>" "identificador" => "aff3" ] 3 => array:3 [ "entidad" => "Servicio de Oncología, Clínica Girona, Girona, Spain" "etiqueta" => "<span class="elsevierStyleSup">d</span>" "identificador" => "aff4" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor1" "etiqueta" => "*" "correspondencia" => "Correspondence: C. Bidegain. Clínica Girona. Joan Maragall, 26. 17002 Girona. España" ] ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2004-04-19" "fechaAceptado" => "2004-05-18" "PalabrasClave" => array:2 [ "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key Words" "identificador" => "xpalclavsec153939" "palabras" => array:3 [ 0 => "Cancer-associated retinopathy" 1 => "Small cell lung cancer" 2 => "Paraneoplastic syndromes" ] ] ] "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec153940" "palabras" => array:3 [ 0 => "Retinopatía asociada a cáncer" 1 => "Carcinoma microcítico" 2 => "Síndromes paraneoplásicos" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "en" => array:1 [ "resumen" => "<p class="elsevierStyleSimplePara elsevierViewall">We report the case of a patient who presented with cancer-associated retinopathy and small cell carcinoma of the lung, which was treated surgically because the initial diagnostic biopsy finding was squamous cell carcinoma. The patient then underwent chemotherapy and radiation therapy. We discuss the characteristics and pathogenesis of this paraneoplastic syndrome as well as its association with the lung tumor's aberrant production of a protein that competes with retinal recoverin at the photoreceptors of the retinal cone.</p>" ] "es" => array:1 [ "resumen" => "<p class="elsevierStyleSimplePara elsevierViewall">Se presenta el caso de un paciente afectado de una retinopatía asociada a cáncer, con un carcinoma microcítico de pulmón tratado quirúrgicamente, ya que la biopsia del diag-nóstico inicial fue positiva para carcinoma epidermoide, y luego con quimio y radioterapia. Se analizan las caracterís-ticas de este síndrome paraneoplásico, su mecanismo pato-génico y su asociación con la producción anómala de una proteína por el tumor pulmonar que compite con la recove-rina autóctona en los receptores de los conos retinianos.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "REFERENCES" "seccion" => array:1 [ 0 => array:1 [ "bibliografiaReferencia" => array:19 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Síndromes paraneoplásicos neurológicos" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "M Thomson" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "LibroEditado" => array:5 [ "titulo" => "Harrison's principles of internal medicine" "paginaInicial" => "708" "paginaFinal" => "710" "edicion" => "14th ed." 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| Year/Month | Html | Total | |
|---|---|---|---|
| 2024 November | 2 | 5 | 7 |
| 2024 October | 25 | 14 | 39 |
| 2024 September | 37 | 19 | 56 |
| 2024 August | 41 | 30 | 71 |
| 2024 July | 31 | 20 | 51 |
| 2024 June | 26 | 27 | 53 |
| 2024 May | 34 | 28 | 62 |
| 2024 April | 17 | 22 | 39 |
| 2024 March | 16 | 16 | 32 |
| 2024 February | 20 | 20 | 40 |
| 2023 April | 0 | 1 | 1 |
| 2023 March | 1 | 2 | 3 |
| 2023 February | 20 | 18 | 38 |
| 2023 January | 15 | 36 | 51 |
| 2022 December | 19 | 31 | 50 |
| 2022 November | 22 | 21 | 43 |
| 2022 October | 19 | 32 | 51 |
| 2022 September | 12 | 20 | 32 |
| 2022 August | 18 | 32 | 50 |
| 2022 July | 18 | 43 | 61 |
| 2022 June | 18 | 30 | 48 |
| 2022 May | 18 | 28 | 46 |
| 2022 April | 16 | 33 | 49 |
| 2022 March | 18 | 38 | 56 |
| 2022 February | 17 | 18 | 35 |
| 2022 January | 14 | 32 | 46 |
| 2021 December | 16 | 33 | 49 |
| 2021 November | 17 | 34 | 51 |
| 2021 October | 13 | 28 | 41 |
| 2021 September | 17 | 37 | 54 |
| 2021 August | 10 | 24 | 34 |
| 2021 July | 12 | 27 | 39 |
| 2021 June | 13 | 33 | 46 |
| 2021 May | 18 | 29 | 47 |
| 2021 April | 17 | 56 | 73 |
| 2021 March | 7 | 15 | 22 |
| 2021 February | 14 | 19 | 33 |
| 2021 January | 11 | 6 | 17 |
| 2020 December | 13 | 8 | 21 |
| 2020 November | 9 | 16 | 25 |
| 2020 October | 5 | 3 | 8 |
| 2020 September | 39 | 11 | 50 |
| 2020 August | 42 | 5 | 47 |
| 2020 July | 28 | 18 | 46 |
| 2020 June | 8 | 9 | 17 |
| 2020 May | 33 | 12 | 45 |
| 2020 April | 29 | 6 | 35 |
| 2020 March | 9 | 18 | 27 |
| 2020 February | 68 | 16 | 84 |
| 2020 January | 53 | 10 | 63 |
| 2019 December | 20 | 24 | 44 |
| 2019 November | 19 | 14 | 33 |
| 2019 October | 7 | 8 | 15 |
| 2019 September | 8 | 10 | 18 |
| 2019 August | 8 | 12 | 20 |
| 2019 July | 12 | 15 | 27 |
| 2019 June | 2 | 6 | 8 |
| 2019 May | 7 | 14 | 21 |
| 2019 April | 9 | 30 | 39 |
| 2019 March | 6 | 26 | 32 |
| 2019 February | 8 | 10 | 18 |
| 2019 January | 9 | 13 | 22 |
| 2018 December | 6 | 18 | 24 |
| 2018 November | 15 | 16 | 31 |
| 2018 October | 15 | 19 | 34 |
| 2018 September | 6 | 13 | 19 |
| 2018 May | 3 | 0 | 3 |
| 2018 April | 3 | 8 | 11 |
| 2018 March | 7 | 4 | 11 |
| 2018 February | 6 | 9 | 15 |
| 2018 January | 1 | 9 | 10 |
| 2017 December | 4 | 11 | 15 |
| 2017 November | 3 | 10 | 13 |
| 2017 October | 4 | 17 | 21 |
| 2017 September | 3 | 13 | 16 |
| 2017 August | 9 | 21 | 30 |
| 2017 July | 3 | 10 | 13 |
| 2017 June | 9 | 44 | 53 |
| 2017 May | 7 | 18 | 25 |
| 2017 April | 3 | 10 | 13 |
| 2017 March | 3 | 22 | 25 |
| 2017 February | 1 | 4 | 5 |
| 2017 January | 2 | 10 | 12 |
| 2016 December | 6 | 11 | 17 |
| 2016 November | 12 | 11 | 23 |
| 2016 October | 22 | 18 | 40 |
| 2016 September | 15 | 13 | 28 |
| 2016 August | 9 | 7 | 16 |
| 2016 July | 4 | 6 | 10 |
| 2016 April | 1 | 0 | 1 |
| 2016 March | 2 | 0 | 2 |
| 2015 December | 2 | 0 | 2 |
| 2015 October | 63 | 1 | 64 |
| 2015 September | 61 | 3 | 64 |
| 2015 August | 63 | 7 | 70 |
| 2015 July | 62 | 11 | 73 |
| 2015 June | 50 | 5 | 55 |
| 2015 May | 61 | 10 | 71 |
| 2015 April | 48 | 3 | 51 |
| 2015 March | 48 | 5 | 53 |
| 2015 February | 55 | 5 | 60 |
| 2015 January | 62 | 5 | 67 |
| 2014 December | 58 | 3 | 61 |
| 2014 November | 62 | 7 | 69 |
| 2014 October | 74 | 8 | 82 |
| 2014 September | 60 | 5 | 65 |
| 2014 August | 39 | 10 | 49 |
| 2014 July | 45 | 7 | 52 |
| 2014 June | 56 | 6 | 62 |
| 2014 May | 65 | 9 | 74 |
| 2014 April | 74 | 9 | 83 |
| 2014 March | 60 | 16 | 76 |
| 2014 February | 52 | 6 | 58 |
| 2014 January | 45 | 8 | 53 |
| 2013 December | 49 | 8 | 57 |
| 2013 November | 33 | 3 | 36 |
| 2013 October | 32 | 6 | 38 |
| 2013 September | 37 | 27 | 64 |
| 2013 August | 59 | 8 | 67 |
| 2013 July | 51 | 10 | 61 |
| 2013 June | 36 | 6 | 42 |
| 2013 May | 31 | 8 | 39 |
| 2013 April | 27 | 7 | 34 |
| 2013 March | 4 | 1 | 5 |
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