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        "resumen" => "<span class="elsevierStyleSectionTitle">Objective</span><p class="elsevierStyleSimplePara elsevierViewall">To validate a cardiorespiratory polygraphy system &#40;BITMED NGP 140&#41; by comparing it to conventional polysomnography in the diagnosis of sleep apnea-hypopnea syndrome&#46;</p> <span class="elsevierStyleSectionTitle">Patients and methods</span><p class="elsevierStyleSimplePara elsevierViewall">Polysomnography and cardiorespiratory polygraphy were performed simultaneously on 103 consecutive patients referred because of suspected sleep apnea-hypopnea syndrome&#46; The Bland and Altman method and intraclass correlation coefficients were used to assess agreement between the 2 methods of measurement&#46; Receiver operating characteristic &#40;ROC&#41; curves were used to calculate the yield of cardiorespiratory polygraphy compared to that of conventional polysomnography&#46;</p> <span class="elsevierStyleSectionTitle">Results</span><p class="elsevierStyleSimplePara elsevierViewall">Ninety-two valid studies were obtained for 72 men and 20 women &#40;mean &#91;SD&#93; age&#58; 52&#46;4 &#91;12&#93; years&#41;&#46; By the Bland and Altman method&#44; the difference between the respiratory event index obtained with the BITMED NGP140 and the apnea-hypopnea index &#40;AHI&#41; obtained by conventional polysomnography was 7&#46;6 &#40;13&#46;2&#41; in the manual analysis &#40;95&#37; confidence interval &#91;CI&#93;&#44; 4&#46;9-10&#46;4&#41; and 12 &#40;15&#46;3&#41; &#40;95&#37; CI&#44; 8&#46;8-15&#46;3&#41; in the automatic analysis&#46; For a corrected AHI &#40;AH&#47;total time in bed&#41; mean differences were -2&#46;2 &#40;5&#46;9&#41; and 2&#46;4 &#40;8&#46;2&#41; for manual and automatic analyses&#46; The intraclass correlation coefficients were greater than 0&#46;94&#46;</p><p class="elsevierStyleSimplePara elsevierViewall">The areas under the ROC curves of the respiratory event index were greater than 0&#46;97 for all cut points&#46; For an AHI of 30 or higher&#44; the best cut-off point determined by manual cardiorespiratory polygraphy analysis was 27 &#40;sensitivity&#44; 98&#37; and specificity&#44; 98&#37;&#41;&#46; For the different cut-off points cardiorespiratory polygraphy correctly classified between 92&#37; and 98&#37; of patients in both the manual and automatic analyses&#46;</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p class="elsevierStyleSimplePara elsevierViewall">The BITMED NGP140 had good agreement with conventional polysomnography for the measurement of respiratory events and provided high diagnostic yield&#46;</p>"
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        "resumen" => "<span class="elsevierStyleSectionTitle">Objetivo</span><p class="elsevierStyleSimplePara elsevierViewall">Validar un dispositivo de poligraf&#237;a &#40;PGR&#41; cardiorrespiratoria&#44; BITMED NGP140&#44; frente a la polisomno-graf&#237;a convencional &#40;PSG&#41; en el s&#237;ndrome de apneas e hipopneas durante el sue&#241;o&#46;</p> <span class="elsevierStyleSectionTitle">Pacientes Y M&#233;todos</span><p class="elsevierStyleSimplePara elsevierViewall">Se realiz&#243; PSG y&#44; simult&#225;neamente&#44; PGR a 103 pacientes consecutivos enviados por sospecha de s&#237;ndrome de apneas e hipopneas durante el sue&#241;o&#46; Se aplicaron el m&#233;todo de Bland y Altman&#44; y el coeficiente de correlaci&#243;n intraclase para analizar la concordancia de los 2 dispositivos&#46; La rentabilidad diagn&#243;stica de la PGR frente a la PSG se calcul&#243; mediante las curvas de eficacia diagn&#243;stica&#46;</p> <span class="elsevierStyleSectionTitle">Resultados</span><p class="elsevierStyleSimplePara elsevierViewall">Se obtuvieron 92 estudios v&#225;lidos&#44; en 72 varones y 20 mujeres con una media de edad &#40;&#177; desviaci&#243;n est&#225;ndar&#41; de 52&#44;4 &#177; 12 a&#241;os&#46; Con el m&#233;todo de Bland y Altman la diferencia del &#237;ndice de eventos respiratorios del BITMED NGP140 con el &#237;ndice de apneashipopneas &#40;IAH&#41; de la PSG era&#44; en el an&#225;lisis manual&#44; de 7&#44;6 &#177; 13&#44;2 &#40;intervalo de confianza del 95&#37;&#44; 4&#44;9-10&#44;4&#41;&#44; y en el an&#225;lisis autom&#225;tico&#44; de 12 &#177; 15&#44;3 &#40;intervalo de confianza del 95&#37;&#44; 8&#44;8-15&#44;3&#41;&#44; mientras que para el IAH corregido &#40;IAH&#47;tiempo total de registro&#41; la media de la diferencia fue de -2&#44;2 &#177; 5&#44;9 en el an&#225;lisis manual y de 2&#44;4 &#177; 8&#44;2 en el autom&#225;tico&#46; Las correlaciones intraclase eran superiores a 0&#44;94&#46;</p><p class="elsevierStyleSimplePara elsevierViewall">Las &#225;reas bajo la curva de eficacia diagn&#243;stica del &#237;ndice de eventos respiratorios eran superiores a 0&#44;97 en todos los puntos de corte&#46; Para un IAH de 30 o superior&#44; el mejor punto de corte del an&#225;lisis manual de la PGR era de 27 &#40;sensibilidad del 98&#37; y especificidad del 98&#37;&#41;&#46; Para los diferentes puntos de corte&#44; la PGR clasificaba correctamente entre el 92 y el 98&#37; de los pacientes tanto con el an&#225;lisis manual como con el autom&#225;tico&#46;</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p class="elsevierStyleSimplePara elsevierViewall">El BITMED NGP140 tiene una buena concordancia con la PSG en la medici&#243;n de los eventos respiratorios y ofrece un alto rendimiento diagn&#243;stico&#46;</p>"
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Original Articles
Validation of a Respiratory Polygraphy System in the Diagnosis of Sleep Apnea Syndrome
A. Candelaa,
Corresponding author
candela_alf@gva.es

Correspondence: Dr. A. Candela. Servicio de Neumología. Hospital General Universitario de Alicante. PintorBaeza, s/n. 03010 Alicante. España
, L. Hernándeza, S. Asensioa, J. Sánchez-Payáb, J. Vilaa, N. Benitoa, S. Romeroa
a Servicio de Neumología, Hospital General Universitario de Alicante, Alicante, Spain
b Servicio de Medicina Preventiva, Hospital General Universitario de Alicante, Alicante, Spain
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        "resumen" => "<span class="elsevierStyleSectionTitle">Objective</span><p class="elsevierStyleSimplePara elsevierViewall">To validate a cardiorespiratory polygraphy system &#40;BITMED NGP 140&#41; by comparing it to conventional polysomnography in the diagnosis of sleep apnea-hypopnea syndrome&#46;</p> <span class="elsevierStyleSectionTitle">Patients and methods</span><p class="elsevierStyleSimplePara elsevierViewall">Polysomnography and cardiorespiratory polygraphy were performed simultaneously on 103 consecutive patients referred because of suspected sleep apnea-hypopnea syndrome&#46; The Bland and Altman method and intraclass correlation coefficients were used to assess agreement between the 2 methods of measurement&#46; Receiver operating characteristic &#40;ROC&#41; curves were used to calculate the yield of cardiorespiratory polygraphy compared to that of conventional polysomnography&#46;</p> <span class="elsevierStyleSectionTitle">Results</span><p class="elsevierStyleSimplePara elsevierViewall">Ninety-two valid studies were obtained for 72 men and 20 women &#40;mean &#91;SD&#93; age&#58; 52&#46;4 &#91;12&#93; years&#41;&#46; By the Bland and Altman method&#44; the difference between the respiratory event index obtained with the BITMED NGP140 and the apnea-hypopnea index &#40;AHI&#41; obtained by conventional polysomnography was 7&#46;6 &#40;13&#46;2&#41; in the manual analysis &#40;95&#37; confidence interval &#91;CI&#93;&#44; 4&#46;9-10&#46;4&#41; and 12 &#40;15&#46;3&#41; &#40;95&#37; CI&#44; 8&#46;8-15&#46;3&#41; in the automatic analysis&#46; For a corrected AHI &#40;AH&#47;total time in bed&#41; mean differences were -2&#46;2 &#40;5&#46;9&#41; and 2&#46;4 &#40;8&#46;2&#41; for manual and automatic analyses&#46; The intraclass correlation coefficients were greater than 0&#46;94&#46;</p><p class="elsevierStyleSimplePara elsevierViewall">The areas under the ROC curves of the respiratory event index were greater than 0&#46;97 for all cut points&#46; For an AHI of 30 or higher&#44; the best cut-off point determined by manual cardiorespiratory polygraphy analysis was 27 &#40;sensitivity&#44; 98&#37; and specificity&#44; 98&#37;&#41;&#46; For the different cut-off points cardiorespiratory polygraphy correctly classified between 92&#37; and 98&#37; of patients in both the manual and automatic analyses&#46;</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p class="elsevierStyleSimplePara elsevierViewall">The BITMED NGP140 had good agreement with conventional polysomnography for the measurement of respiratory events and provided high diagnostic yield&#46;</p>"
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        "resumen" => "<span class="elsevierStyleSectionTitle">Objetivo</span><p class="elsevierStyleSimplePara elsevierViewall">Validar un dispositivo de poligraf&#237;a &#40;PGR&#41; cardiorrespiratoria&#44; BITMED NGP140&#44; frente a la polisomno-graf&#237;a convencional &#40;PSG&#41; en el s&#237;ndrome de apneas e hipopneas durante el sue&#241;o&#46;</p> <span class="elsevierStyleSectionTitle">Pacientes Y M&#233;todos</span><p class="elsevierStyleSimplePara elsevierViewall">Se realiz&#243; PSG y&#44; simult&#225;neamente&#44; PGR a 103 pacientes consecutivos enviados por sospecha de s&#237;ndrome de apneas e hipopneas durante el sue&#241;o&#46; Se aplicaron el m&#233;todo de Bland y Altman&#44; y el coeficiente de correlaci&#243;n intraclase para analizar la concordancia de los 2 dispositivos&#46; La rentabilidad diagn&#243;stica de la PGR frente a la PSG se calcul&#243; mediante las curvas de eficacia diagn&#243;stica&#46;</p> <span class="elsevierStyleSectionTitle">Resultados</span><p class="elsevierStyleSimplePara elsevierViewall">Se obtuvieron 92 estudios v&#225;lidos&#44; en 72 varones y 20 mujeres con una media de edad &#40;&#177; desviaci&#243;n est&#225;ndar&#41; de 52&#44;4 &#177; 12 a&#241;os&#46; Con el m&#233;todo de Bland y Altman la diferencia del &#237;ndice de eventos respiratorios del BITMED NGP140 con el &#237;ndice de apneashipopneas &#40;IAH&#41; de la PSG era&#44; en el an&#225;lisis manual&#44; de 7&#44;6 &#177; 13&#44;2 &#40;intervalo de confianza del 95&#37;&#44; 4&#44;9-10&#44;4&#41;&#44; y en el an&#225;lisis autom&#225;tico&#44; de 12 &#177; 15&#44;3 &#40;intervalo de confianza del 95&#37;&#44; 8&#44;8-15&#44;3&#41;&#44; mientras que para el IAH corregido &#40;IAH&#47;tiempo total de registro&#41; la media de la diferencia fue de -2&#44;2 &#177; 5&#44;9 en el an&#225;lisis manual y de 2&#44;4 &#177; 8&#44;2 en el autom&#225;tico&#46; Las correlaciones intraclase eran superiores a 0&#44;94&#46;</p><p class="elsevierStyleSimplePara elsevierViewall">Las &#225;reas bajo la curva de eficacia diagn&#243;stica del &#237;ndice de eventos respiratorios eran superiores a 0&#44;97 en todos los puntos de corte&#46; Para un IAH de 30 o superior&#44; el mejor punto de corte del an&#225;lisis manual de la PGR era de 27 &#40;sensibilidad del 98&#37; y especificidad del 98&#37;&#41;&#46; Para los diferentes puntos de corte&#44; la PGR clasificaba correctamente entre el 92 y el 98&#37; de los pacientes tanto con el an&#225;lisis manual como con el autom&#225;tico&#46;</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p class="elsevierStyleSimplePara elsevierViewall">El BITMED NGP140 tiene una buena concordancia con la PSG en la medici&#243;n de los eventos respiratorios y ofrece un alto rendimiento diagn&#243;stico&#46;</p>"
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