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        "resumen" => "<span class="elsevierStyleSectionTitle">Objective</span><p class="elsevierStyleSimplePara elsevierViewall">Immunocompromised children are at high risk for developing pneumonia due to opportunistic pathogens&#46; The role of bronchoalveolar lavage &#40;BAL&#41; in the evaluation of such patients is still controversial&#46;</p> <span class="elsevierStyleSectionTitle">Material and Method</span><p class="elsevierStyleSimplePara elsevierViewall">We reviewed the hospital records of immunosuppressed patients with respiratory symptoms who had undergone BAL in the pediatric department of the Hospital Cl&#237;nico de la Pontificia Universidad Cat&#243;lica of Chile&#46;</p> <span class="elsevierStyleSectionTitle">Results</span><p class="elsevierStyleSimplePara elsevierViewall">Sixty-eight BAL were performed on 54 children &#40;mean age&#58; 7&#46;5 years&#41; receiving wide-spectrum antibiotic treatment&#46; The most frequent respiratory signs and symptoms were fever &#40;90&#37;&#41; and cough and respiratory distress &#40;81&#37;&#41;&#59; 18&#37; had neutropenia and 43&#37; thrombocytopenia&#46; A specific pathogen was identified in BAL samples for 25 patients &#40;37&#37;&#41;&#46; The pathogens isolated were bacteria in 21 cases&#44; viruses in 6&#44; <span class="elsevierStyleItalic">Pneumocystis carinii</span> in 5&#44; fungi in 4&#44; and <span class="elsevierStyleItalic">Mycobacterium tuberculosis</span> in one&#46; Fourteen &#40;19&#37;&#41; of the children who underwent BAL were on mechanical ventilation&#46; Outcome was satisfactory in all cases&#46; Twenty-one complications were recorded&#44; 17 of which were minor &#40;mild hypoxemia or fever&#41; and 4 major&#44; requiring tracheal intubation&#46; No deaths were recorded&#46;</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p class="elsevierStyleSimplePara elsevierViewall">Evaluation by fiberoptic bronchoscopy together with BAL proved to be a safe procedure with an adequate diagnostic yield that made it possible to determine the etiology of the pulmonary infiltrates seen in chest x-rays&#46; Both positive and negative results of BAL were useful for treating the patients&#46;</p>"
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        "resumen" => "<span class="elsevierStyleSectionTitle">Objetivo</span><p class="elsevierStyleSimplePara elsevierViewall">LOS ni&#241;os inmunodeprimidos presentan el ries-go de desarrollar neumon&#237;a por g&#233;rmenes oportunistas&#46; El papel del lavado broncoalveolar &#40;LBA&#41; en la evaluaci&#243;n de estos pacientes es a&#250;n controvertido&#46;</p> <span class="elsevierStyleSectionTitle">Material Y M&#233;todo</span><p class="elsevierStyleSimplePara elsevierViewall">Se revisaron las fichas de pacientes con inmunodepresi&#243;n y s&#237;ntomas respiratorios a los que se les hab&#237;a practicado un LBA en el Servicio de Pediatr&#237;a del Hospital Cl&#237;nico de la Pontificia Universidad Cat&#243;lica de Chile&#46;</p> <span class="elsevierStyleSectionTitle">Resultados</span><p class="elsevierStyleSimplePara elsevierViewall">Se practicaron 68 LBA en 54 ni&#241;os inmunodeprimidos &#40;edad media&#58; 7&#44;5 a&#241;os&#41;&#46; Los s&#237;ntomas respiratorios m&#225;s frecuentes fueron fiebre &#40;90&#37;&#41; y tos y dificultad respiratoria &#40;81&#37;&#41;&#59; el 18&#37; ten&#237;a neutropenia y el 43&#37;&#44; trombocitopenia&#46; Todos los pacientes estaban en tratamiento antibi&#243;tico de amplio espectro&#46; Las muestras del LBA pro-porcionaron un germen espec&#237;fico en 25 pacientes &#40;37&#37;&#41;&#46; Los pat&#243;genos aislados fueron&#58; bacterias en 21 casos&#44; virus en 6&#44; <span class="elsevierStyleItalic">Pneumocystis carinii</span> en 5&#44; hongos en 4 y <span class="elsevierStyleItalic">Mycobacterium tuberculosis</span> en uno&#46; Catorce &#40;19&#37;&#41; LBA se realizaron a ni&#241;os que recib&#237;an ventilaci&#243;n mec&#225;nica&#46; La evoluci&#243;n fue sa-tisfactoria en todos los casos&#46; Se registraron 21 complicaciones&#44; 17 menores &#40;hipoxemia leve o fiebre&#41; y 4 mayores que requirieron intubaci&#243;n traqueal&#46; No se registraron muertes&#46;</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p class="elsevierStyleSimplePara elsevierViewall">La evaluaci&#243;n fibrobroncosc&#243;pica asocia-da a un LBA fue un m&#233;todo seguro&#44; con un adecuado rendimiento&#44; que permiti&#243; evaluar la etiolog&#237;a de los infiltrados pulmonares en la radiograf&#237;a de t&#243;rax&#46; Tanto los resultados positivos como los negativos del LBA contribuyeron al tratamiento de estos pacientes&#46;</p>"
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Original Articles
Utility of Bronchoalveolar Lavage in Immunocompromised Children: Diagnostic Yield and Complications
L.E. Vega-Briceñoa,
Corresponding author
LEvega@puc.cl

Correspondence: Dr. L.E. Vega-Briceño. Sección de Respiratorio Pediátrico. Departamento de Pediatría. Pontificia Universidad Católica de Chile. Lira, 85, 5°piso. Laboratorio de Respiratorio. Santiago de Chile. Chile
, N.L. Holmgrena, P. Bertranda, J.I. Rodríguezb, F. Barrigac, I. Contrerasa, I. Sáncheza
a Sección de Respiratorio Pediátrico, Departamento de Pediatría, Pontificia Universidad Católica de Chile, Santiago de Chile, Chile
b Unidad de Cuidados Intensivos Pediátricos, Departamento de Pediatría, Pontificia Universidad Católica de Chile, Santiago de Chile, Chile
c Sección de Oncología Pediátrica, Departamento de Pediatría, Pontificia Universidad Católica de Chile, Santiago de Chile, Chile
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ISSN: 15792129
Original language: English
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