Correspondence: Dr. N. Santana Rodríguez. Unidad de Cirugía Torácica. Clínica San Roque. C/ Juan E. Doreste, 11. 35001 Las Palmas de Gran Canaria. España
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Izquierdo Alonso, J.M. Rodríguez González-Moro, P. de Lucas Ramos, J.M. Bellón Cano, J. Molina París" "autores" => array:6 [ 0 => array:2 [ "nombre" => "J." "apellidos" => "de Miguel Díez" ] 1 => array:3 [ "preGrado" => "Dr." "nombre" => "J.L." "apellidos" => "Izquierdo Alonso" ] 2 => array:2 [ "nombre" => "J.M." "apellidos" => "Rodríguez González-Moro" ] 3 => array:2 [ "nombre" => "P." "apellidos" => "de Lucas Ramos" ] 4 => array:2 [ "nombre" => "J.M." "apellidos" => "Bellón Cano" ] 5 => array:2 [ "nombre" => "J." "apellidos" => "Molina París" ] ] ] ] ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1579212906603510?idApp=UINPBA00003Z" "url" => "/15792129/0000004000000010/v1_201305141820/S1579212906603510/v1_201305141820/en/main.assets" ] "en" => array:15 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Original Articles</span>" "titulo" => "Lung Transplantation in Rats: a Viable Experimental Model" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "438" "paginaFinal" => "442" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "N. Santana Rodríguez, J.L. Martín Barrasa, A. López García, P. Rodríguez Suárez, M. Ponce González, J. Freixinet Gilart" "autores" => array:6 [ 0 => array:5 [ "preGrado" => "Dr." "nombre" => "N." "apellidos" => "Santana Rodríguez" "email" => array:1 [ 0 => "norbesr@terra.es" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor1" ] ] ] 1 => array:3 [ "nombre" => "J.L." "apellidos" => "Martín Barrasa" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff2" ] ] ] 2 => array:3 [ "nombre" => "A." "apellidos" => "López García" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">c</span>" "identificador" => "aff3" ] ] ] 3 => array:3 [ "nombre" => "P." "apellidos" => "Rodríguez Suárez" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff2" ] ] ] 4 => array:3 [ "nombre" => "M." 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"apellidos" => "Freixinet Gilart" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff2" ] ] ] ] "afiliaciones" => array:3 [ 0 => array:3 [ "entidad" => "Unidad de Cirugía Torácica, Clínica San Roque, Las Palmas de Gran Canaria, Spain" "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] 1 => array:3 [ "entidad" => "Unidad de Cirugía Torácica, Unidad de Investigación, Hospital Universitario Dr. Negrín, Las Palmas de Gran Canaria, Spain" "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff2" ] 2 => array:3 [ "entidad" => "Servicio de Anatomía Patológica, Hospital Universitario Puerta de Hierro, Madrid, Spain" "etiqueta" => "<span class="elsevierStyleSup">c</span>" "identificador" => "aff3" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor1" "etiqueta" => "*" "correspondencia" => "Correspondence: Dr. N. Santana Rodríguez. Unidad de Cirugía Torácica. Clínica San Roque. C/ Juan E. Doreste, 11. 35001 Las Palmas de Gran Canaria. España" ] ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2003-11-13" "fechaAceptado" => "2004-03-23" "PalabrasClave" => array:2 [ "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key Words" "identificador" => "xpalclavsec153122" "palabras" => array:3 [ 0 => "Lung transplant" 1 => "Experimental surgery" 2 => "Experimental transplant" ] ] ] "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec153123" "palabras" => array:3 [ 0 => "Trasplante pulmonar" 1 => "Cirugía experimental" 2 => "Trasplante experimental" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "en" => array:1 [ "resumen" => "<span class="elsevierStyleSectionTitle">Objectives</span><p class="elsevierStyleSimplePara elsevierViewall">TO incorporate a new fast, safe, and reversible anesthetic procedure into the experimental model of lung transplantation (LT) using a cuff technique originally described by Mizuta.</p> <span class="elsevierStyleSectionTitle">Material and Method</span><p class="elsevierStyleSimplePara elsevierViewall">Eighty-eight Sprague-Dawley rats were used in the experimental model. Thirty left LTs were performed, using 60 rats. The donor heart-lung block was excised by median sternotomy with dissection of the left lung and cuffs (intravenous catheters cut into 3-mm sections) were put in place. The left lung was implanted in the recipient by lateral thoracotomy using the cuffs for anastomoses. The duration of surgery and postoperative complications were recorded. Also noted were signs of ischemia-reperfusion injury, and acute rejection of the transplanted lung.</p> <span class="elsevierStyleSectionTitle">Results</span><p class="elsevierStyleSimplePara elsevierViewall">We discarded lungs excised from 8 animals when developing the experimental model. Transplants could not be completed in 10 rats due to technical problems, despite satisfactory excision. Of the rats who received a transplant, 4 died in the first 24 hours and 26 survived to 48 hours. They were then killed and examined. The state of the anastomoses was good and signs of ischemia-reperfusion injury, as well as acute rejection were observed in the parenchyma of the transplanted lung.</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p class="elsevierStyleSimplePara elsevierViewall">LT with cuffs in rats is a valid, reliable, reproducible, and cheap model for studying ischemia-reperfusion injury and rejection in LT. The surgical technique is complex, requiring experienced surgeons and a long learning process. Modification of the technique to more closely resemble the surgical procedure in humans is possible, thus facilitating interpretation and allowing more reliable extrapolation to humans.</p>" ] "es" => array:1 [ "resumen" => "<span class="elsevierStyleSectionTitle">Objetivos</span><p class="elsevierStyleSimplePara elsevierViewall">Desarrollar el modelo experimental de trasplante pulmonar (TP) con <span class="elsevierStyleItalic">cuffs</span> (técnica de manguito), inicialmente descrito por Mizuta, como medio de estudio del TP en nuestro medio incorporando un nuevo protocolo anestésico rápido, seguro y reversible.</p> <span class="elsevierStyleSectionTitle">Material Y Método</span><p class="elsevierStyleSimplePara elsevierViewall">Se han utilizado ratas Sprague-Dawley (n = 88) para el desarrollo del modelo experimental y se han logrado realizar 30 TP izquierdos (n = 60). En el animal donante se han efectuado una esternotomía media y extracción del bloque cardiopulmonar con disección del pulmón izquierdo y colocación de los <span class="elsevierStyleItalic">cuffs</span> (catéteres de venopunción cortados en cilindros de 3 mm). En el receptor, a través de una toracotomía lateral, se ha llevado a cabo el implante del pulmón izquierdo mediante las anastomosis con <span class="elsevierStyleItalic">cuffs.</span> Se han valorado el tiempo quirúrgico y las complicaciones postoperatorias, así como la presencia de signos de lesión de isquemia-reperfusión y rechazo agudo en el pulmón trasplantado.</p> <span class="elsevierStyleSectionTitle">Resultados</span><p class="elsevierStyleSimplePara elsevierViewall">Durante el desarrollo del modelo experimental rechazamos a 8 animales en la extracción. Tras com-pletarla satisfactoriamente, no se pudo realizar el implante en 10 ratas por problemas técnicos. De los animales trasplantados, 4 fallecieron en las primeras 24 h y 26 ratas sobrevivieron hasta las 48 h, momento en que fueron sacrificadas. Hallamos un buen estado de las anastomosis y signos de lesión de isquemia-reperfusión y rechazo agudo en el parénquima pulmonar del pulmón trasplantado.</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p class="elsevierStyleSimplePara elsevierViewall">El TP con <span class="elsevierStyleItalic">cuffs</span> en ratas es un modelo válido, fiable, reproducible y económico para el estudio del TP y de los fenómenos de isquemia-reperfusión y rechazo. La técnica quirúrgica es compleja, tiene una larga curva de aprendizaje y requiere personal con experiencia quirúrgica. Además, es subsidiaria de modificaciones que hagan que se asemeje más a la técnica quirúrgica utilizada en clínica humana para interpretar mejor y poder extrapolar los resultados al humano con más fiabilidad.</p>" ] ] "NotaPie" => array:1 [ 0 => array:1 [ "nota" => "<p class="elsevierStyleNotepara">This project was funded by the Health Research Fund (FIS).</p>" ] ] "bibliografia" => array:2 [ "titulo" => "REFERENCES" "seccion" => array:1 [ 0 => array:1 [ "bibliografiaReferencia" => array:14 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Trasplante pulmonar. Normativa SEPAR" "autores" => array:1 [ 0 => array:2 [ "colaboracion" => "Grupo de Trabajo de Trasplante Pulmonar SEPAR" "etal" => false ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Arch Bronconeumol" "fecha" => "2001" "volumen" => "37" "paginaInicial" => "307" "paginaFinal" => "315" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11562316" "web" => "Medline" ] ] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib2" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:1 [ "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "V Demikov" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Libro" => array:4 [ "titulo" => "Experimental transplantation of vital organ" "fecha" => "1962" "editorial" => "Consultants Bureau Enterprises, Inc." "editorialLocalizacion" => "New York" ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib3" "etiqueta" => "3" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Lung allografts in dogs treated with methotrexate and antilymphocyte serum" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "DA Blumenstock" 1 => "HP Otte" 2 => "OV Grosjean" 3 => "MA Mulder" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Ann Thorac Surg" "fecha" => "1968" "volumen" => "6" "paginaInicial" => "33" "paginaFinal" => "39" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/4394021" "web" => "Medline" ] ] ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib4" "etiqueta" => "4" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Lung transplantation in the rat" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "PJ Asimacopoulos" 1 => "FAS Molokhia" 2 => "CAS Pegg" 3 => "JC Norman" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Transplant Proc" "fecha" => "1971" "volumen" => "3" "paginaInicial" => "583" "paginaFinal" => "585" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/4937944" "web" => "Medline" ] ] ] ] ] ] ] ] 4 => array:3 [ "identificador" => "bib5" "etiqueta" => "5" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Lung transplantation in the rat: I. Technique and survival" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "KW Marck" 1 => "CR Wildevuur" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Ann Thorac Surg" "fecha" => "1982" "volumen" => "34" "paginaInicial" => "74" "paginaFinal" => "80" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7046662" "web" => "Medline" ] ] ] ] ] ] ] ] 5 => array:3 [ "identificador" => "bib6" "etiqueta" => "6" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Simplified rat lung transplantation using a cuff technique" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "T Mizuta" 1 => "A Kawaguchi" 2 => "K Nakahara" 3 => "Y Kawashima" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Thorac Cardiovasc Surg" "fecha" => "1989" "volumen" => "97" "paginaInicial" => "578" "paginaFinal" => "581" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2648080" "web" => "Medline" ] ] ] ] ] ] ] ] 6 => array:3 [ "identificador" => "bib7" "etiqueta" => "7" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Improved outcome of rat lung transplantation with modification of the non suture external cuff technique" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "A Reis" 1 => "A Giaid" 2 => "C Serrick" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Heart Lung Transplant" "fecha" => "1995" "volumen" => "14" "paginaInicial" => "274" "paginaFinal" => "279" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7779846" "web" => "Medline" ] ] ] ] ] ] ] ] 7 => array:3 [ "identificador" => "bib8" "etiqueta" => "8" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "A simplified model for en bloc double lung xeno-transplantation from hamster to rat" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "M de Perrot" 1 => "S Keshavjee" 2 => "T Tabata" 3 => "M Liu" 4 => "GP Downey" 5 => "TK Waddell" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Heart Lung Transplant" "fecha" => "2002" "volumen" => "21" "paginaInicial" => "286" "paginaFinal" => "289" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11834358" "web" => "Medline" ] ] ] ] ] ] ] ] 8 => array:3 [ "identificador" => "bib9" "etiqueta" => "9" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Nitroglycerin alters alveolar type II cell ultrastructure after ischemia and reperfusion" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "A Fehrenbach" 1 => "T Wittwer" 2 => "D Meyer" 3 => "S von Vietinghoff" 4 => "M Viehover" 5 => "H Fehrenbach" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "J Heart Lung Transplant" "fecha" => "2001" "volumen" => "20" "paginaInicial" => "876" "paginaFinal" => "888" ] ] ] ] ] ] 9 => array:3 [ "identificador" => "bib10" "etiqueta" => "10" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Effect of a single injection of high-dose FK506 on lung transplantation in rats" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "Y Sano" 1 => "S Maruyama" 2 => "M Aoe" 3 => "H Date" 4 => "N Shimizu" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Surg Today" "fecha" => "1996" "volumen" => "26" "paginaInicial" => "999" "paginaFinal" => "1005" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9017963" "web" => "Medline" ] ] ] ] ] ] ] ] 10 => array:3 [ "identificador" => "bib11" "etiqueta" => "11" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Effect of ischemic injury on subsequent rat lung allograft rejection" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "T Shiraishi" 1 => "T Mizuta" 2 => "SR DeMeester" 3 => "JH Ritter" 4 => "PE Swanson" 5 => "MR Wick" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Ann Thorac Surg" "fecha" => "1995" "volumen" => "60" "paginaInicial" => "947" "paginaFinal" => "951" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7575000" "web" => "Medline" ] ] ] ] ] ] ] ] 11 => array:3 [ "identificador" => "bib12" "etiqueta" => "12" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Ischemia-reperfusion-induced lung injury" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "M de Perrot" 1 => "M Liu" 2 => "T Waddell" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Am Resp J Crit Care Med" "fecha" => "2003" "volumen" => "167" "paginaInicial" => "490" "paginaFinal" => "511" ] ] ] ] ] ] 12 => array:3 [ "identificador" => "bib13" "etiqueta" => "13" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Improved distribution of pulmonary flush solution to the traqueobronchial wall in pulmonary transplantation" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "A Varela" 1 => "CG Montero" 2 => "M Córdoba" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Eur Surg Res" "fecha" => "1997" "volumen" => "29" "paginaInicial" => "1" "paginaFinal" => "4" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9286322" "web" => "Medline" ] ] ] ] ] ] ] ] 13 => array:3 [ "identificador" => "bib14" "etiqueta" => "14" "referencia" => array:1 [ 0 => array:2 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Year/Month | Html | Total | |
---|---|---|---|
2024 November | 4 | 4 | 8 |
2024 October | 28 | 16 | 44 |
2024 September | 29 | 15 | 44 |
2024 August | 48 | 37 | 85 |
2024 July | 25 | 22 | 47 |
2024 June | 27 | 20 | 47 |
2024 May | 32 | 31 | 63 |
2024 April | 22 | 19 | 41 |
2024 March | 13 | 17 | 30 |
2024 February | 23 | 18 | 41 |
2023 March | 2 | 4 | 6 |
2023 February | 21 | 17 | 38 |
2023 January | 13 | 26 | 39 |
2022 December | 18 | 24 | 42 |
2022 November | 20 | 15 | 35 |
2022 October | 17 | 25 | 42 |
2022 September | 14 | 19 | 33 |
2022 August | 15 | 31 | 46 |
2022 July | 16 | 38 | 54 |
2022 June | 16 | 32 | 48 |
2022 May | 26 | 36 | 62 |
2022 April | 17 | 23 | 40 |
2022 March | 24 | 41 | 65 |
2022 February | 15 | 21 | 36 |
2022 January | 17 | 33 | 50 |
2021 December | 15 | 37 | 52 |
2021 November | 16 | 37 | 53 |
2021 October | 13 | 34 | 47 |
2021 September | 15 | 38 | 53 |
2021 August | 11 | 35 | 46 |
2021 July | 8 | 19 | 27 |
2021 June | 12 | 32 | 44 |
2021 May | 18 | 23 | 41 |
2021 April | 10 | 26 | 36 |
2021 March | 20 | 18 | 38 |
2021 February | 6 | 7 | 13 |
2021 January | 6 | 6 | 12 |
2020 December | 10 | 8 | 18 |
2020 November | 8 | 10 | 18 |
2020 October | 8 | 6 | 14 |
2020 September | 4 | 0 | 4 |
2020 August | 14 | 7 | 21 |
2020 July | 6 | 15 | 21 |
2020 June | 14 | 5 | 19 |
2020 May | 15 | 9 | 24 |
2020 April | 12 | 11 | 23 |
2020 March | 10 | 9 | 19 |
2020 February | 14 | 13 | 27 |
2020 January | 19 | 14 | 33 |
2019 December | 19 | 15 | 34 |
2019 November | 6 | 10 | 16 |
2019 October | 5 | 5 | 10 |
2019 September | 10 | 10 | 20 |
2019 August | 9 | 6 | 15 |
2019 July | 7 | 16 | 23 |
2019 June | 5 | 9 | 14 |
2019 May | 14 | 35 | 49 |
2019 April | 31 | 45 | 76 |
2019 March | 12 | 25 | 37 |
2019 February | 2 | 13 | 15 |
2019 January | 7 | 10 | 17 |
2018 December | 10 | 18 | 28 |
2018 November | 10 | 11 | 21 |
2018 October | 16 | 17 | 33 |
2018 September | 12 | 11 | 23 |
2018 May | 4 | 0 | 4 |
2018 April | 7 | 10 | 17 |
2018 March | 5 | 3 | 8 |
2018 February | 3 | 6 | 9 |
2018 January | 6 | 8 | 14 |
2017 December | 7 | 10 | 17 |
2017 November | 0 | 6 | 6 |
2017 October | 6 | 18 | 24 |
2017 September | 3 | 6 | 9 |
2017 August | 8 | 18 | 26 |
2017 July | 2 | 6 | 8 |
2017 June | 9 | 20 | 29 |
2017 May | 10 | 9 | 19 |
2017 April | 3 | 5 | 8 |
2017 March | 4 | 10 | 14 |
2017 February | 2 | 1 | 3 |
2017 January | 1 | 2 | 3 |
2016 December | 13 | 10 | 23 |
2016 November | 15 | 11 | 26 |
2016 October | 16 | 15 | 31 |
2016 September | 26 | 10 | 36 |
2016 August | 11 | 3 | 14 |
2016 July | 8 | 4 | 12 |
2016 March | 2 | 0 | 2 |
2015 December | 2 | 0 | 2 |
2015 October | 53 | 1 | 54 |
2015 September | 56 | 19 | 75 |
2015 August | 47 | 9 | 56 |
2015 July | 101 | 9 | 110 |
2015 June | 48 | 12 | 60 |
2015 May | 78 | 13 | 91 |
2015 April | 39 | 13 | 52 |
2015 March | 65 | 7 | 72 |
2015 February | 39 | 4 | 43 |
2015 January | 30 | 4 | 34 |
2014 December | 39 | 7 | 46 |
2014 November | 43 | 9 | 52 |
2014 October | 86 | 15 | 101 |
2014 September | 64 | 9 | 73 |
2014 August | 46 | 10 | 56 |
2014 July | 56 | 5 | 61 |
2014 June | 55 | 7 | 62 |
2014 May | 70 | 9 | 79 |
2014 April | 65 | 6 | 71 |
2014 March | 77 | 5 | 82 |
2014 February | 80 | 8 | 88 |
2014 January | 63 | 8 | 71 |
2013 December | 62 | 9 | 71 |
2013 November | 50 | 9 | 59 |
2013 October | 51 | 8 | 59 |
2013 September | 55 | 7 | 62 |
2013 August | 39 | 14 | 53 |
2013 July | 71 | 17 | 88 |
2013 June | 65 | 8 | 73 |
2013 May | 47 | 15 | 62 |
2013 April | 20 | 7 | 27 |
2013 March | 8 | 4 | 12 |