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Variability Among Pathologists in the Histological Diagnosis of Diffuse Interstitial Lung Diseases
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"apellidos" => "Sánchez-Varilla" "email" => array:1 [ 0 => "sanchezva@terra.es" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor1" ] ] ] 1 => array:3 [ "nombre" => "S." "apellidos" => "Recio-Gallardo" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff2" ] ] ] 2 => array:3 [ "nombre" => "J.M." "apellidos" => "Benítez-Moya" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] ] ] 3 => array:3 [ "nombre" => "V." "apellidos" => "Almadana-Pacheco" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] ] ] 4 => array:3 [ "nombre" => "J." "apellidos" => "Peña de Bustillo" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] ] ] 5 => array:3 [ "nombre" => "V." "apellidos" => "Martínez-Puentes" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] ] ] ] "afiliaciones" => array:2 [ 0 => array:3 [ "entidad" => "Servicio de Neumología, Hospital Universitario Virgen Macarena, Sevilla, Spain" "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] 1 => array:3 [ "entidad" => "Servicio de Radiología, Hospital Universitario Virgen Macarena, Sevilla, Spain" "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff2" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor1" "etiqueta" => "*" "correspondencia" => "Correspondence: Dr. J.M. Sánchez-Varilla. Alejandro Collantes 26, P 2, 2.° B. 41005 Sevilla. España" ] ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2004-10-07" "fechaAceptado" => "2005-04-04" "PalabrasClave" => array:2 [ "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key Words" "identificador" => "xpalclavsec153718" "palabras" => array:4 [ 0 => "Diffuse idiopathic interstitial pneumonia" 1 => "Variability" 2 => "Histology" 3 => "Agreement" ] ] ] "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec153719" "palabras" => array:4 [ 0 => "Neumonía intersticial difusa idiopática" 1 => "Variabilidad" 2 => "Histología" 3 => "Discordancia" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "en" => array:1 [ "resumen" => "<span class="elsevierStyleSectionTitle">Objective</span><p class="elsevierStyleSimplePara elsevierViewall">Diffuse interstitial lung diseases (DILD) form a group of diseases which affect the alveolar interstitial space and share very similar clinical, radiological, and functional features, making lung biopsy essential for establishing diagnosis, prognosis, and treatment in many cases. We aimed to see whether there was agreement in histopathological diagnosis among different groups of pathologists in their assessment of these diseases.</p> <span class="elsevierStyleSectionTitle">Material and methods</span><p class="elsevierStyleSimplePara elsevierViewall">Biopsies were studied from 33 patients suffering from noninfectious, nontumorous DILD. The biopsies had been assessed by 2 groups of pathologists: one specializing in this type of disease and another which was not a specialist group.</p> <span class="elsevierStyleSectionTitle">Results</span><p class="elsevierStyleSimplePara elsevierViewall">There was disagreement in the histology reports of 10 out of the 33 cases studied (30.3%): 9 cases in the group of 22 cases of idiopathic interstitial pneumonia (40.9%) and 1 in the group of 3 DILD with known or associated causes. No discrepancies were found, however, in the diagnosis of primary DILD or DILD associated with other, less well-defined processes.</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p class="elsevierStyleSimplePara elsevierViewall">We believe that idiopathic interstitial pneumonias are the DILD which pose most problems for pathologists. Therefore, the study of DILD requires specific dedication by pathologists and other professionals and specialists.</p>" ] "es" => array:1 [ "resumen" => "<span class="elsevierStyleSectionTitle">Objetivo</span><p class="elsevierStyleSimplePara elsevierViewall">Las enfermedades pulmonares intersticiales difusas (EPID) son un conjunto de enfermedades que afecta al espacio alveolointersticial, con manifestaciones clínicas, radiológicas y funcionales muy similares, por lo que en muchos casos el estudio de la biopsia pulmonar será fundamental para el diagnóstico, pronóstico y tratamiento. Hemos querido ver si hay o no concordancia histopatológica diagnóstica, entre diferentes grupos de patólogos, en la valoración de estas enfermedades.</p> <span class="elsevierStyleSectionTitle">Material y métodos</span><p class="elsevierStyleSimplePara elsevierViewall">Se han estudiado las biopsias de 33 pacientes afectados de EPID no infecciosa ni tumoral, las cuales han sido valoradas por 2 grupos de patólogos: uno con especial interés por este tipo de enfermedades, y otro grupo no dedicado especialmente a esta enfermedad.</p> <span class="elsevierStyleSectionTitle">Resultados</span><p class="elsevierStyleSimplePara elsevierViewall">Al confrontar posteriormente los resultados, observamos en los informes histológicos una discordancia en el diagnóstico de 10 de los 33 casos estudiados (30,3%), 9 de ellos en el grupo de las 22 neumonías intersticiales idiopáticas (40,9%) y un caso en el grupo de las 3 EPID de causas conocidas o asociadas. Sin embargo, no encontramos ninguna discrepancia en el grupo de EPID primarias o asociadas a otros procesos no bien conocidos.</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p class="elsevierStyleSimplePara elsevierViewall">Creemos que las neumonías intersticiales idiopáticas son el grupo de EPID que más problemas de diagnóstico histológico pueden plantear al patólogo. Por tanto, es fundamental una especial dedicación por parte de estos profesionales y de los distintos especialistas que están relacionados con el estudio de las EPID.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "REFERENCES" "seccion" => array:1 [ 0 => array:1 [ "bibliografiaReferencia" => array:15 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Área de Técnicas y Trasplante. SEPAR. 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| Year/Month | Html | Total | |
|---|---|---|---|
| 2024 November | 3 | 2 | 5 |
| 2024 October | 32 | 13 | 45 |
| 2024 September | 23 | 14 | 37 |
| 2024 August | 36 | 31 | 67 |
| 2024 July | 31 | 18 | 49 |
| 2024 June | 31 | 18 | 49 |
| 2024 May | 38 | 28 | 66 |
| 2024 April | 19 | 26 | 45 |
| 2024 March | 15 | 11 | 26 |
| 2024 February | 19 | 14 | 33 |
| 2023 March | 5 | 5 | 10 |
| 2023 February | 20 | 22 | 42 |
| 2023 January | 15 | 26 | 41 |
| 2022 December | 22 | 27 | 49 |
| 2022 November | 16 | 32 | 48 |
| 2022 October | 19 | 30 | 49 |
| 2022 September | 20 | 27 | 47 |
| 2022 August | 21 | 34 | 55 |
| 2022 July | 17 | 36 | 53 |
| 2022 June | 15 | 28 | 43 |
| 2022 May | 19 | 31 | 50 |
| 2022 April | 19 | 28 | 47 |
| 2022 March | 20 | 32 | 52 |
| 2022 February | 12 | 28 | 40 |
| 2022 January | 16 | 30 | 46 |
| 2021 December | 12 | 47 | 59 |
| 2021 November | 15 | 43 | 58 |
| 2021 October | 17 | 42 | 59 |
| 2021 September | 23 | 48 | 71 |
| 2021 August | 9 | 20 | 29 |
| 2021 July | 10 | 28 | 38 |
| 2021 June | 18 | 36 | 54 |
| 2021 May | 10 | 21 | 31 |
| 2021 April | 24 | 54 | 78 |
| 2021 March | 17 | 20 | 37 |
| 2021 February | 15 | 18 | 33 |
| 2021 January | 15 | 15 | 30 |
| 2020 December | 13 | 18 | 31 |
| 2020 November | 9 | 7 | 16 |
| 2020 October | 15 | 7 | 22 |
| 2020 September | 7 | 8 | 15 |
| 2020 August | 8 | 14 | 22 |
| 2020 July | 17 | 16 | 33 |
| 2020 June | 9 | 4 | 13 |
| 2020 May | 22 | 15 | 37 |
| 2020 April | 18 | 14 | 32 |
| 2020 March | 14 | 15 | 29 |
| 2020 February | 11 | 19 | 30 |
| 2020 January | 22 | 36 | 58 |
| 2019 December | 14 | 15 | 29 |
| 2019 November | 11 | 15 | 26 |
| 2019 October | 9 | 8 | 17 |
| 2019 September | 6 | 11 | 17 |
| 2019 August | 12 | 7 | 19 |
| 2019 July | 7 | 21 | 28 |
| 2019 June | 7 | 8 | 15 |
| 2019 May | 9 | 24 | 33 |
| 2019 April | 11 | 31 | 42 |
| 2019 March | 12 | 14 | 26 |
| 2019 February | 14 | 15 | 29 |
| 2019 January | 5 | 12 | 17 |
| 2018 December | 7 | 15 | 22 |
| 2018 November | 7 | 12 | 19 |
| 2018 October | 15 | 21 | 36 |
| 2018 September | 13 | 11 | 24 |
| 2018 May | 6 | 0 | 6 |
| 2018 April | 9 | 8 | 17 |
| 2018 March | 3 | 0 | 3 |
| 2018 February | 6 | 8 | 14 |
| 2018 January | 3 | 8 | 11 |
| 2017 December | 7 | 4 | 11 |
| 2017 November | 6 | 4 | 10 |
| 2017 October | 7 | 6 | 13 |
| 2017 September | 1 | 10 | 11 |
| 2017 August | 7 | 11 | 18 |
| 2017 July | 5 | 6 | 11 |
| 2017 June | 4 | 6 | 10 |
| 2017 May | 9 | 12 | 21 |
| 2017 April | 2 | 1 | 3 |
| 2017 March | 3 | 5 | 8 |
| 2017 February | 3 | 6 | 9 |
| 2017 January | 3 | 2 | 5 |
| 2016 December | 8 | 9 | 17 |
| 2016 November | 15 | 4 | 19 |
| 2016 October | 21 | 17 | 38 |
| 2016 September | 11 | 10 | 21 |
| 2016 August | 11 | 5 | 16 |
| 2016 July | 7 | 8 | 15 |
| 2016 March | 3 | 0 | 3 |
| 2016 February | 2 | 0 | 2 |
| 2015 December | 1 | 0 | 1 |
| 2015 October | 29 | 1 | 30 |
| 2015 September | 35 | 15 | 50 |
| 2015 August | 24 | 6 | 30 |
| 2015 July | 43 | 9 | 52 |
| 2015 June | 23 | 9 | 32 |
| 2015 May | 39 | 13 | 52 |
| 2015 April | 27 | 6 | 33 |
| 2015 March | 22 | 8 | 30 |
| 2015 February | 19 | 4 | 23 |
| 2015 January | 19 | 5 | 24 |
| 2014 December | 32 | 5 | 37 |
| 2014 November | 28 | 5 | 33 |
| 2014 October | 51 | 8 | 59 |
| 2014 September | 28 | 7 | 35 |
| 2014 August | 30 | 7 | 37 |
| 2014 July | 40 | 8 | 48 |
| 2014 June | 49 | 11 | 60 |
| 2014 May | 43 | 9 | 52 |
| 2014 April | 33 | 4 | 37 |
| 2014 March | 36 | 9 | 45 |
| 2014 February | 42 | 9 | 51 |
| 2014 January | 18 | 4 | 22 |
| 2013 December | 36 | 12 | 48 |
| 2013 November | 31 | 6 | 37 |
| 2013 October | 35 | 9 | 44 |
| 2013 September | 41 | 6 | 47 |
| 2013 August | 58 | 20 | 78 |
| 2013 July | 48 | 23 | 71 |
| 2013 June | 35 | 10 | 45 |
| 2013 May | 48 | 11 | 59 |
| 2013 April | 17 | 7 | 24 |
| 2013 March | 11 | 3 | 14 |
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