Correspondence: Dr. M.A. Alonso-Fernández. Servicio de Neumología I. Hospital Universitario Central de Asturias. Dr. Bellmunt, s/n. 33006 Oviedo. Asturias. España
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Menéndez, A. Torres" "autores" => array:2 [ 0 => array:3 [ "preGrado" => "Dr." "nombre" => "R." "apellidos" => "Menéndez" ] 1 => array:2 [ "nombre" => "A." "apellidos" => "Torres" ] ] ] ] ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1579212906602656?idApp=UINPBA00003Z" "url" => "/15792129/0000004100000009/v1_201305150225/S1579212906602656/v1_201305150225/en/main.assets" ] "en" => array:14 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Original Articles</span>" "titulo" => "Characteristics of Lung Cancer in a Region in Northern Spain" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "478" "paginaFinal" => "483" ] ] "autores" => array:1 [ 0 => array:3 [ "autoresLista" => "M.A. Alonso-Fernández, M. García-Clemente, C. Escudero-Bueno" "autores" => array:4 [ 0 => array:5 [ "preGrado" => "Dr." "nombre" => "M.A." "apellidos" => "Alonso-Fernández" "email" => array:1 [ 0 => "migu67@separ.es" ] "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor1" ] ] ] 1 => array:2 [ "nombre" => "M." "apellidos" => "García-Clemente" ] 2 => array:2 [ "nombre" => "C." "apellidos" => "Escudero-Bueno" ] 3 => array:1 [ "colaborador" => "for the Asturian Society of Respiratory Disease (ASTURPAR) Lung Cancer Working Group (GACP)" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor1" "etiqueta" => "*" "correspondencia" => "Correspondence: Dr. M.A. Alonso-Fernández. Servicio de Neumología I. Hospital Universitario Central de Asturias. Dr. Bellmunt, s/n. 33006 Oviedo. Asturias. España" ] ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2004-11-03" "fechaAceptado" => "2005-04-16" "PalabrasClave" => array:2 [ "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key Words" "identificador" => "xpalclavsec154144" "palabras" => array:3 [ 0 => "Lung cancer" 1 => "Incidence" 2 => "Survival" ] ] ] "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec154143" "palabras" => array:3 [ 0 => "Cáncer de pulmón" 1 => "Incidencia" 2 => "Supervivencia" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "en" => array:1 [ "resumen" => "<span class="elsevierStyleSectionTitle">Objective</span><p class="elsevierStyleSimplePara elsevierViewall">TO gather information on the disease characteristics and survival rate of patients diagnosed with bronchogenic carcinoma in the respiratory medicine departments of hospitals in Asturias, Spain.</p> <span class="elsevierStyleSectionTitle">Patientsand methods</span><p class="elsevierStyleSimplePara elsevierViewall">This was a retrospective observational study carried out using a standardized data collection protocol. All cases of lung cancer diagnosed during 2001 were included provided there was cytologic or histologic confirmation or they fulfilled a series of clinical, radiological, and/or endoscopic criteria consistent with such a diagnosis.</p> <span class="elsevierStyleSectionTitle">Results</span><p class="elsevierStyleSimplePara elsevierViewall">Standard incidence rates adjusted to the world population were 22.4, 42.6, and 4.6 per 100 000 population for the whole population, men, and women respectively. The mean (SD) age was 67 (10.9) years, and 92% of the patients were men. Overall, 98% of the men and 44% of the women were smokers. Diagnosis was confirmed by cytologic or histologic findings in 92% of patients, and the majority were non-small cell tumors (81.4%). At the time of diagnosis, 65% of the patients had advanced disease, with distant metastasis in 26.6% of the non-small cell cancers and 52.8% of the small cell cancers. Patients received surgical treatment in 21.3% of cases, chemotherapy alone or combined with radiation therapy in 43.1%, and radiation therapy alone in 9.3%. In 26.2% of patients only palliative care was given. Overall, median survival in weeks was 36.4 (95% confidence interval [CI], 29.4-43.4). Median survival by treatment type was as follows: 69.3 (95% CI, 49-9.5) for surgery; 39.6 (95% CI, 31.2-48) for chemotherapy alone or with radiation therapy; 30 (95% CI, 15.4-44.6) for radiation therapy alone; and 13.3 (95% CI, 5.9-20.6) for patients who received palliative care alone (<span class="elsevierStyleItalic">P</span><.05).</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p class="elsevierStyleSimplePara elsevierViewall">The findings with respect to age, sex, incidence, histology, extent of tumor, and smoking status of patients with bronchogenic carcinoma in our region do not differ significantly from those reported for other areas of Spain. Current smoking is the primary cause of the high prevalence of this disease. Twenty-six percent of patients received only palliative care. The percentage of patients treated with surgery was low.</p>" ] "es" => array:1 [ "resumen" => "<span class="elsevierStyleSectionTitle">Objetivo</span><p class="elsevierStyleSimplePara elsevierViewall">Conocer las características y supervivencia del carcinoma broncogénico (CB) diagnosticado en las unidades de neumología del Principado de Asturias.</p> <span class="elsevierStyleSectionTitle">Pacientes y métodos</span><p class="elsevierStyleSimplePara elsevierViewall">Se ha realizado un estudio observacional retrospectivo en el que se ha empleado un protocolo común de recogida de datos. Se incluyeron los CB diagnosticados en el año 2001 con confirmación citohistológica o por concordancia basada en datos clínicos, radiológicos y/o endoscópicos.</p> <span class="elsevierStyleSectionTitle">Resultados</span><p class="elsevierStyleSimplePara elsevierViewall">Las tasas de incidencia estándar para toda la población, varones y mujeres, ajustadas a la población mundial fueron de 22,4, 42,6 y 4,6/100.000 habitantes, respectivamente. El 92% era varón; la edad media (± desviación estándar) fue de 67 ± 10,9 años. Tenía hábito tabáquico el 98% de los varones y el 44% de las mujeres. Se alcanzó confirmación citohistológica en el 92% y la mayoría era CB no microcíticos (81,4%). En el momento del diagnóstico el 65% de los pacientes tenía enfermedad avanzada, con metástasis a distancia en el 26,6% de los CB no microcíticos y en el 52,8% de los de células pequeñas. Se trató con cirugía el 21,3% de los casos, con quimioterapia sola o asociada a radioterapia el 43,1%, con radioterapia exclusivamente el 9,3% y recibió tratamiento paliativo el 26,2%. La mediana de supervivencia global, en semanas, fue de 36,4 (intervalo de confianza [IC] del 95%, 29,4-43,4) y para los distintos tratamientos fue la siguiente: para la cirugía, 69,3 (IC del 95%, 49-9,5); para la quimioterapia sola o asociada a radioterapia, 39,6 (IC del 95%, 31,2-48); para la radioterapia sola, 30 (IC del 95%, 15,4-44,6), y para el paliativo, 13,3 (IC del 95%, 5,9-20,6) (p < 0,05).</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p class="elsevierStyleSimplePara elsevierViewall">En nuestra región, las características del CB en cuanto a edad, sexo, incidencia, histología, extensión tumoral y tabaquismo no difieren significativamente de las halladas en otras áreas del ámbito nacional. El tabaquismo activo es la causa fundamental de su alta prevalencia. Se ofreció solamente tratamiento de soporte al 26%. El porcentaje de pacientes quirúrgicos es bajo.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "REFERENCES" "seccion" => array:1 [ 0 => array:1 [ "bibliografiaReferencia" => array:31 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "El cáncer de pulmón en España. 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Year/Month | Html | Total | |
---|---|---|---|
2024 November | 1 | 2 | 3 |
2024 October | 29 | 21 | 50 |
2024 September | 25 | 13 | 38 |
2024 August | 46 | 39 | 85 |
2024 July | 31 | 26 | 57 |
2024 June | 29 | 25 | 54 |
2024 May | 35 | 29 | 64 |
2024 April | 18 | 22 | 40 |
2024 March | 15 | 15 | 30 |
2024 February | 16 | 24 | 40 |
2023 March | 2 | 5 | 7 |
2023 February | 26 | 17 | 43 |
2023 January | 14 | 26 | 40 |
2022 December | 16 | 25 | 41 |
2022 November | 24 | 21 | 45 |
2022 October | 18 | 27 | 45 |
2022 September | 15 | 22 | 37 |
2022 August | 26 | 46 | 72 |
2022 July | 39 | 42 | 81 |
2022 June | 42 | 34 | 76 |
2022 May | 28 | 39 | 67 |
2022 April | 24 | 32 | 56 |
2022 March | 19 | 32 | 51 |
2022 February | 16 | 27 | 43 |
2022 January | 14 | 34 | 48 |
2021 December | 15 | 45 | 60 |
2021 November | 14 | 52 | 66 |
2021 October | 20 | 49 | 69 |
2021 September | 14 | 51 | 65 |
2021 August | 9 | 29 | 38 |
2021 July | 11 | 32 | 43 |
2021 June | 12 | 36 | 48 |
2021 May | 9 | 28 | 37 |
2021 April | 58 | 40 | 98 |
2021 March | 19 | 28 | 47 |
2021 February | 14 | 22 | 36 |
2021 January | 13 | 14 | 27 |
2020 December | 7 | 10 | 17 |
2020 November | 3 | 14 | 17 |
2020 October | 10 | 7 | 17 |
2020 September | 7 | 5 | 12 |
2020 August | 10 | 10 | 20 |
2020 July | 10 | 20 | 30 |
2020 June | 9 | 3 | 12 |
2020 May | 17 | 15 | 32 |
2020 April | 10 | 15 | 25 |
2020 March | 14 | 12 | 26 |
2020 February | 11 | 14 | 25 |
2020 January | 15 | 11 | 26 |
2019 December | 13 | 15 | 28 |
2019 November | 6 | 15 | 21 |
2019 October | 4 | 5 | 9 |
2019 September | 1 | 10 | 11 |
2019 August | 15 | 6 | 21 |
2019 July | 10 | 25 | 35 |
2019 June | 5 | 12 | 17 |
2019 May | 10 | 12 | 22 |
2019 April | 11 | 27 | 38 |
2019 March | 12 | 18 | 30 |
2019 February | 11 | 23 | 34 |
2019 January | 7 | 13 | 20 |
2018 December | 7 | 15 | 22 |
2018 November | 23 | 11 | 34 |
2018 October | 16 | 9 | 25 |
2018 September | 15 | 13 | 28 |
2018 May | 2 | 0 | 2 |
2018 April | 11 | 7 | 18 |
2018 March | 3 | 4 | 7 |
2018 February | 5 | 4 | 9 |
2018 January | 7 | 13 | 20 |
2017 December | 4 | 3 | 7 |
2017 November | 3 | 2 | 5 |
2017 October | 6 | 13 | 19 |
2017 September | 5 | 6 | 11 |
2017 August | 8 | 11 | 19 |
2017 July | 2 | 3 | 5 |
2017 June | 9 | 11 | 20 |
2017 May | 8 | 7 | 15 |
2017 April | 1 | 4 | 5 |
2017 March | 4 | 22 | 26 |
2017 February | 3 | 3 | 6 |
2017 January | 1 | 0 | 1 |
2016 December | 15 | 13 | 28 |
2016 November | 5 | 5 | 10 |
2016 October | 8 | 4 | 12 |
2016 September | 3 | 4 | 7 |
2016 August | 4 | 5 | 9 |
2016 April | 1 | 0 | 1 |
2016 March | 2 | 0 | 2 |
2015 December | 3 | 0 | 3 |
2015 October | 38 | 5 | 43 |
2015 September | 29 | 8 | 37 |
2015 August | 26 | 6 | 32 |
2015 July | 31 | 10 | 41 |
2015 June | 31 | 4 | 35 |
2015 May | 56 | 4 | 60 |
2015 April | 33 | 4 | 37 |
2015 March | 37 | 5 | 42 |
2015 February | 36 | 4 | 40 |
2015 January | 38 | 8 | 46 |
2014 December | 25 | 3 | 28 |
2014 November | 37 | 8 | 45 |
2014 October | 52 | 9 | 61 |
2014 September | 30 | 4 | 34 |
2014 August | 42 | 9 | 51 |
2014 July | 38 | 9 | 47 |
2014 June | 57 | 6 | 63 |
2014 May | 47 | 7 | 54 |
2014 April | 69 | 9 | 78 |
2014 March | 71 | 11 | 82 |
2014 February | 51 | 7 | 58 |
2014 January | 46 | 8 | 54 |
2013 December | 51 | 6 | 57 |
2013 November | 44 | 5 | 49 |
2013 October | 48 | 9 | 57 |
2013 September | 42 | 8 | 50 |
2013 August | 45 | 10 | 55 |
2013 July | 50 | 17 | 67 |
2013 June | 39 | 5 | 44 |
2013 May | 37 | 3 | 40 |
2013 April | 16 | 5 | 21 |
2013 March | 8 | 2 | 10 |