Correspondence: Dr. J. Padilla. Servicio de Cirugía Torácica. Hospital Universitario La Fe. Avda. de Campanar, 21. 46009 Valencia. España
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Vidal Serrano, J. Martín Juan, L. Gómez Izquierdo, I. Sánchez Rodríguez, E. Rodríguez Becerra, F. Rodríguez Panadero" "autores" => array:6 [ 0 => array:3 [ "preGrado" => "Dra." "nombre" => "S." "apellidos" => "Vidal Serrano" ] 1 => array:2 [ "nombre" => "J." "apellidos" => "Martín Juan" ] 2 => array:2 [ "nombre" => "L." "apellidos" => "Gómez Izquierdo" ] 3 => array:2 [ "nombre" => "I." "apellidos" => "Sánchez Rodríguez" ] 4 => array:2 [ "nombre" => "E." "apellidos" => "Rodríguez Becerra" ] 5 => array:2 [ "nombre" => "F." "apellidos" => "Rodríguez Panadero" ] ] ] ] ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1579212906602577?idApp=UINPBA00003Z" "url" => "/15792129/0000004100000008/v1_201305150223/S1579212906602577/v1_201305150223/en/main.assets" ] "en" => array:14 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Original Articles</span>" "titulo" => "T2N1M0 Non-Small Cell Lung Cancer: Surgery and Prognostic Factors" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "430" "paginaFinal" => "433" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "J. Padilla, V. Calvo, J.C. Peñalver, C. Jordá, J. Escrivá, J. Cerón, A. García Zarza, J. Pastor, E. Blasco" "autores" => array:9 [ 0 => array:5 [ "preGrado" => "Dr." "nombre" => "J." "apellidos" => "Padilla" "email" => array:1 [ 0 => "jpadilla@comv.es" ] "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor1" ] ] ] 1 => array:2 [ "nombre" => "V." "apellidos" => "Calvo" ] 2 => array:2 [ "nombre" => "J.C." "apellidos" => "Peñalver" ] 3 => array:2 [ "nombre" => "C." "apellidos" => "Jordá" ] 4 => array:2 [ "nombre" => "J." "apellidos" => "Escrivá" ] 5 => array:2 [ "nombre" => "J." "apellidos" => "Cerón" ] 6 => array:2 [ "nombre" => "A. García" "apellidos" => "Zarza" ] 7 => array:2 [ "nombre" => "J." "apellidos" => "Pastor" ] 8 => array:2 [ "nombre" => "E." "apellidos" => "Blasco" ] ] "afiliaciones" => array:1 [ 0 => array:1 [ "entidad" => "Servicio de Cirugía Torácica, Hospital Universitario La Fe, Valencia, Spain" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor1" "etiqueta" => "*" "correspondencia" => "Correspondence: Dr. J. Padilla. Servicio de Cirugía Torácica. Hospital Universitario La Fe. Avda. de Campanar, 21. 46009 Valencia. España" ] ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2004-08-24" "fechaAceptado" => "2004-11-16" "PalabrasClave" => array:2 [ "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key Words" "identificador" => "xpalclavsec154130" "palabras" => array:5 [ 0 => "Carcinoma bronchogenic" 1 => "Stage IIb" 2 => "T2N1M0" 3 => "Surgery" 4 => "Prognosis" ] ] ] "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec154131" "palabras" => array:5 [ 0 => "Carcinoma broncogénico" 1 => "Estadio IIb" 2 => "T2N1M0" 3 => "Cirugía" 4 => "Factores pronósticos" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "en" => array:1 [ "resumen" => "<span class="elsevierStyleSectionTitle">Objective</span><p class="elsevierStyleSimplePara elsevierViewall">TO determine the prognostic factors for the survival in a group of patients operated on for a non-small cell lung cancer classified as T2N1M0.</p> <span class="elsevierStyleSectionTitle">Patients and methods</span><p class="elsevierStyleSimplePara elsevierViewall">TWO hundred sixteen patients treated exclusively with surgery were studied. Kaplan-Meier survival and Cox multivariable regression analyses were used.</p> <span class="elsevierStyleSectionTitle">Results</span><p class="elsevierStyleSimplePara elsevierViewall">The overall survival rate was 39.8% at 5 years and 29.9% at 10 years. Sex, age, presence or absence of symptoms, type of resection, and number and location of affected lymph nodes had no effect on survival. Tumor size (<span class="elsevierStyleItalic">P</span> = .04) and histologic type (<span class="elsevierStyleItalic">P</span> = .03) did significantly affect prognosis. Both variables entered into the Cox multivariable regression model.</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p class="elsevierStyleSimplePara elsevierViewall">Patients operated on for non-small cell lung cancer classified as T2N1M0 have an overall probability of 5-year survival of approximately 40%. However, the prognosis for this group of patients is heterogeneous: in our study it was affected by the histologic type (45.5% for squamous cell and 25% for non-squamous cell cancers) and tumor size (53% for tumors with a diameter of ≤3 cm, 45% for tumors between 3.1 and 5 cm, and 29% for a tumor diameter >5 cm).</p>" ] "es" => array:1 [ "resumen" => "<span class="elsevierStyleSectionTitle">Objetivo</span><p class="elsevierStyleSimplePara elsevierViewall">Determinar los factores pronósticos de supervi-vencia de un grupo de pacientes operados de un carcinoma broncogénico no anaplásico de células pequeñas y clasifica-dos como T2N1M0.</p> <span class="elsevierStyleSectionTitle">Pacientes y métodos</span><p class="elsevierStyleSimplePara elsevierViewall">Se estudió a 216 pacientes tratados exclusivamente con cirugía. La supervivencia se analizó con el método de Kaplan-Meier y se utilizó el modelo de Cox para el análisis multivariante.</p> <span class="elsevierStyleSectionTitle">Resultados</span><p class="elsevierStyleSimplePara elsevierViewall">La supervivencia global fue del 39,8% a los 5 años y del 29,9% a los 10 años. El sexo, la edad, la presen-cia o ausencia de síntomas, la amplitud de la exéresis, el nú-mero de ganglios afectados y su localización no influyeron en la supervivencia. El tamaño tumoral (p = 0,04) y la estir-pe histológica (p = 0,03) sí condicionaron significativamente el pronóstico. Ambas variables entraron en regresión cuan-do se utilizó el análisis multivariante.</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p class="elsevierStyleSimplePara elsevierViewall">Los pacientes operados de un carcinoma broncogénico no anaplásico de células pequeñas clasificado como T2N1M0 tienen una probabilidad de supervivencia global a los 5 años en torno al 40%. Sin embargo, no es un grupo de pacientes con un pronóstico homogéneo, ya que en nuestro estudio estuvo condicionado por la estirpe histológica (un 45,5% para los epidermoides y un 25% para los no epidermoides) y el tamaño tumoral (un 53% en los tumores con un diámetro ≤ 3 cm, un 45% entre 3,1-5 cm y un 29% en > 5 cm).</p>" ] ] "bibliografia" => array:2 [ "titulo" => "REFERENCES" "seccion" => array:1 [ 0 => array:1 [ "bibliografiaReferencia" => array:20 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Normativa actualizada (1998) sobre diagnóstico y estadificación del carcinoma broncogénico" "autores" => array:1 [ 0 => array:2 [ "colaboracion" => "Grupo de Trabajo de la SEPAR" "etal" => false ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Arch Bronconeumol" "fecha" => "1998" "volumen" => "34" "paginaInicial" => "437" "paginaFinal" => "452" 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Year/Month | Html | Total | |
---|---|---|---|
2024 November | 3 | 3 | 6 |
2024 October | 33 | 22 | 55 |
2024 September | 30 | 25 | 55 |
2024 August | 48 | 44 | 92 |
2024 July | 40 | 19 | 59 |
2024 June | 54 | 35 | 89 |
2024 May | 49 | 28 | 77 |
2024 April | 28 | 25 | 53 |
2024 March | 29 | 15 | 44 |
2024 February | 21 | 27 | 48 |
2023 March | 6 | 5 | 11 |
2023 February | 24 | 33 | 57 |
2023 January | 25 | 22 | 47 |
2022 December | 24 | 32 | 56 |
2022 November | 26 | 23 | 49 |
2022 October | 34 | 38 | 72 |
2022 September | 21 | 16 | 37 |
2022 August | 50 | 46 | 96 |
2022 July | 54 | 42 | 96 |
2022 June | 65 | 32 | 97 |
2022 May | 35 | 45 | 80 |
2022 April | 61 | 35 | 96 |
2022 March | 50 | 34 | 84 |
2022 February | 35 | 48 | 83 |
2022 January | 33 | 31 | 64 |
2021 December | 39 | 54 | 93 |
2021 November | 38 | 50 | 88 |
2021 October | 45 | 50 | 95 |
2021 September | 31 | 51 | 82 |
2021 August | 20 | 29 | 49 |
2021 July | 22 | 29 | 51 |
2021 June | 42 | 48 | 90 |
2021 May | 41 | 40 | 81 |
2021 April | 95 | 65 | 160 |
2021 March | 68 | 23 | 91 |
2021 February | 52 | 28 | 80 |
2021 January | 22 | 13 | 35 |
2020 December | 18 | 15 | 33 |
2020 November | 30 | 17 | 47 |
2020 October | 54 | 6 | 60 |
2020 September | 129 | 11 | 140 |
2020 August | 126 | 20 | 146 |
2020 July | 158 | 25 | 183 |
2020 June | 46 | 10 | 56 |
2020 May | 62 | 32 | 94 |
2020 April | 81 | 26 | 107 |
2020 March | 81 | 37 | 118 |
2020 February | 105 | 19 | 124 |
2020 January | 75 | 20 | 95 |
2019 December | 80 | 17 | 97 |
2019 November | 46 | 14 | 60 |
2019 October | 30 | 11 | 41 |
2019 September | 38 | 12 | 50 |
2019 August | 26 | 18 | 44 |
2019 July | 31 | 24 | 55 |
2019 June | 11 | 16 | 27 |
2019 May | 28 | 22 | 50 |
2019 April | 50 | 31 | 81 |
2019 March | 22 | 19 | 41 |
2019 February | 10 | 14 | 24 |
2019 January | 8 | 12 | 20 |
2018 December | 12 | 14 | 26 |
2018 November | 22 | 14 | 36 |
2018 October | 19 | 23 | 42 |
2018 September | 11 | 10 | 21 |
2018 May | 6 | 1 | 7 |
2018 April | 4 | 8 | 12 |
2018 March | 5 | 13 | 18 |
2018 February | 5 | 13 | 18 |
2018 January | 4 | 7 | 11 |
2017 December | 6 | 11 | 17 |
2017 November | 4 | 17 | 21 |
2017 October | 4 | 13 | 17 |
2017 September | 3 | 19 | 22 |
2017 August | 6 | 16 | 22 |
2017 July | 2 | 19 | 21 |
2017 June | 7 | 19 | 26 |
2017 May | 6 | 19 | 25 |
2017 April | 1 | 11 | 12 |
2017 March | 2 | 21 | 23 |
2017 February | 3 | 14 | 17 |
2017 January | 1 | 2 | 3 |
2016 December | 6 | 10 | 16 |
2016 November | 10 | 12 | 22 |
2016 October | 5 | 8 | 13 |
2016 September | 10 | 13 | 23 |
2016 August | 9 | 3 | 12 |
2016 July | 6 | 4 | 10 |
2016 March | 2 | 0 | 2 |
2015 December | 2 | 0 | 2 |
2015 October | 79 | 1 | 80 |
2015 September | 81 | 11 | 92 |
2015 August | 70 | 13 | 83 |
2015 July | 88 | 7 | 95 |
2015 June | 65 | 4 | 69 |
2015 May | 69 | 7 | 76 |
2015 April | 45 | 7 | 52 |
2015 March | 64 | 6 | 70 |
2015 February | 61 | 4 | 65 |
2015 January | 60 | 4 | 64 |
2014 December | 53 | 7 | 60 |
2014 November | 67 | 6 | 73 |
2014 October | 100 | 8 | 108 |
2014 September | 45 | 5 | 50 |
2014 August | 58 | 6 | 64 |
2014 July | 41 | 8 | 49 |
2014 June | 54 | 4 | 58 |
2014 May | 56 | 9 | 65 |
2014 April | 46 | 5 | 51 |
2014 March | 51 | 8 | 59 |
2014 February | 55 | 8 | 63 |
2014 January | 36 | 9 | 45 |
2013 December | 34 | 6 | 40 |
2013 November | 37 | 8 | 45 |
2013 October | 46 | 3 | 49 |
2013 September | 44 | 5 | 49 |
2013 August | 42 | 7 | 49 |
2013 July | 46 | 27 | 73 |
2013 June | 40 | 9 | 49 |
2013 May | 34 | 6 | 40 |
2013 April | 31 | 5 | 36 |
2013 March | 13 | 1 | 14 |