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        "resumen" => "<span class="elsevierStyleSectionTitle">Objective</span><p class="elsevierStyleSimplePara elsevierViewall">The main objective was to describe the results of lung function testing in a series of 120 patients with pulmonary arterial hypertension&#44; and the secondary objective was to compare these findings with hemodynamic variables&#46;</p> <span class="elsevierStyleSectionTitle">Patients and methods</span><p class="elsevierStyleSimplePara elsevierViewall">This was a descriptive study of lung function in 120 patients with stable pulmonary arterial hypertension &#40;Evian&#47;Venice groups 1 and 4&#41; studied until January 2002 in the Pulmonary Hypertension and Lung Transplant Working Group attached to the Cardiology Department of the Hospital Universtario 12 de Octubre in Madrid&#44; Spain&#46; Data were collected retrospectively for the first 47 patients &#40;1981 to 1995&#41; and prospectively thereafter for the remaining 73 patients&#46; The diagnosis was idiopathic arterial hypertension or hypertension associated with collagen disease&#44; chronic pulmonary embolism&#44; cardiac shunt&#44; or toxic oil syndrome &#40;30 cases&#41;&#46;</p> <span class="elsevierStyleSectionTitle">Results</span><p class="elsevierStyleSimplePara elsevierViewall">In the group as a whole&#44; forced vital capacity&#44; forced expiratory volume in 1 second&#44; and total lung capacity were normal&#59; mean &#40;SD&#41; values revealed low carbon dioxide diffusing capacity &#40;67&#46;6&#37; &#91;23&#46;2&#37;&#93;&#41;&#44; and moderate hypoxemia &#40;65&#46;8 &#91;15&#46;4&#93; mm Hg&#41;&#46; No significant associations were observed between lung function and hemodynamic parameters&#46; Mean age in the toxic oil syndrome group was lower &#40;33&#46;7 &#91;11&#46;4&#93; years&#41;&#44; and these patients had higher mean scores on the New York Heart Association scale &#40;3&#46;3 &#91;0&#46;5&#93;&#41; and for pulmonary vascular resistance &#40;20&#46;3 &#91;8&#46;1&#93; kPa&#183;L<span class="elsevierStyleSup">-1</span>&#183;s&#41;&#46;</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p class="elsevierStyleSimplePara elsevierViewall">Lung function was studied in a series of 120 patients with pulmonary arterial hypertension &#40;Evian&#47; Venice groups 1 and 4&#41;&#44; 30 of whom had toxic oil syndrome&#46; No significant associations were found between lung function and hemodynamic parameters&#46;</p>"
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        "resumen" => "<span class="elsevierStyleSectionTitle">Objetivo</span><p class="elsevierStyleSimplePara elsevierViewall">El objetivo principal es la descripci&#243;n de los hallazgos funcionales respiratorios en una serie de 120 pacientes con hipertensi&#243;n arterial pulmonar &#40;HAP&#41;&#44; y el objetivo secundario es su comparaci&#243;n con los datos hemodin&#225;micos&#46;</p> <span class="elsevierStyleSectionTitle">Pacientes y m&#233;todos</span><p class="elsevierStyleSimplePara elsevierViewall">Estudio descriptivo de la funci&#243;n pulmonar de los 120 casos con HAP estable&#44; de los grupos 1 y 4 de Evian&#47;Venecia&#44; estudiados hasta enero de 2002 en el grupo de trabajo de Hipertensi&#243;n Pulmonar y Trasplante de Pulm&#243;n del Servicio de Cardiolog&#237;a del Hospital Universitario 12 de Octubre de Madrid&#46; Los datos de 47 pacientes se recogieron retrospectivamente desde 1981 a 1995&#44; y de forma prospectiva en los 73 restantes&#46; Se incluyeron casos de hipertensi&#243;n arterial idiop&#225;tica y de la asociada a colagenosis&#44; tromboembolia pulmonar cr&#243;nica&#44; <span class="elsevierStyleItalic">shunt</span> card&#237;aco y&#44; en 30 casos&#44; a s&#237;ndrome de aceite t&#243;xico &#40;SAT&#41;&#46;</p> <span class="elsevierStyleSectionTitle">Resultados</span><p class="elsevierStyleSimplePara elsevierViewall">En el conjunto del grupo la capacidad vital&#44; el volumen espiratorio forzado en el primer segundo y la capacidad pulmonar total fueron normales&#59; los valores medios mostraron un factor de transferencia bajo &#40;media &#177; desvia-ci&#243;n est&#225;ndar&#58; 67&#44;6 &#177; 23&#44;2&#41;&#44; e hipoxemia moderada &#40;65&#44;8 &#177; 15&#44;4 mmHg&#41;&#46; No se observaron asociaciones significativas entre los par&#225;metros funcionales pulmonares y los hemodin&#225;micos&#46; El grupo con SAT ten&#237;a la edad m&#225;s baja &#40;33&#44;7 &#177; 11&#44;4 a&#241;os&#41;&#44; junto a los valores medios m&#225;s altos en la escala de la New York Heart Association &#40;3&#44;3 &#177; 0&#44;5&#41; y de resistencias vasculares pulmonares &#40;20&#44;3 &#177; 8&#44;1 kPa&#183;l<span class="elsevierStyleSup">-1</span>&#183;s&#41;&#46;</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p class="elsevierStyleSimplePara elsevierViewall">En este trabajo se estudia la funci&#243;n pulmonar en una serie de 120 pacientes con HAP&#44; de los grupos 1 y 4 de Evian&#47;Venecia&#44; entre los que se incluy&#243; a 30 casos con SAT&#46; No se han encontrado asociaciones significativas entre los valores funcionales respiratorios y los hemodin&#225;micos&#46;</p>"
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Original Articles
Lung Function Testing in Patients With Pulmonary Arterial Hypertension
P. Martín Escribanoa,
Corresponding author
pmartin.hdoc@salud.madrid.org

Correspondence: Dr. P. Martín Escribano. Servicio de Neumología. Hospital Universitario 12 de Octubre. Avda. Córdoba, s/n. 28041 Madrid. España
, M.A. Gómez Sánchezb, M.J. Díaz de Atauria, J. Palomera Fradea, I. Martín Garcíac
a Servicio de Neumología, Hospital Universitario 12 de Octubre, Madrid, Spain
b Servicio de Cardiología, Hospital Universitario 12 de Octubre, Madrid, Spain
c Unidad de Epidemiología Clínica, Hospital Universitario 12 de Octubre, Madrid, Spain
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        "resumen" => "<span class="elsevierStyleSectionTitle">Objective</span><p class="elsevierStyleSimplePara elsevierViewall">The main objective was to describe the results of lung function testing in a series of 120 patients with pulmonary arterial hypertension&#44; and the secondary objective was to compare these findings with hemodynamic variables&#46;</p> <span class="elsevierStyleSectionTitle">Patients and methods</span><p class="elsevierStyleSimplePara elsevierViewall">This was a descriptive study of lung function in 120 patients with stable pulmonary arterial hypertension &#40;Evian&#47;Venice groups 1 and 4&#41; studied until January 2002 in the Pulmonary Hypertension and Lung Transplant Working Group attached to the Cardiology Department of the Hospital Universtario 12 de Octubre in Madrid&#44; Spain&#46; Data were collected retrospectively for the first 47 patients &#40;1981 to 1995&#41; and prospectively thereafter for the remaining 73 patients&#46; The diagnosis was idiopathic arterial hypertension or hypertension associated with collagen disease&#44; chronic pulmonary embolism&#44; cardiac shunt&#44; or toxic oil syndrome &#40;30 cases&#41;&#46;</p> <span class="elsevierStyleSectionTitle">Results</span><p class="elsevierStyleSimplePara elsevierViewall">In the group as a whole&#44; forced vital capacity&#44; forced expiratory volume in 1 second&#44; and total lung capacity were normal&#59; mean &#40;SD&#41; values revealed low carbon dioxide diffusing capacity &#40;67&#46;6&#37; &#91;23&#46;2&#37;&#93;&#41;&#44; and moderate hypoxemia &#40;65&#46;8 &#91;15&#46;4&#93; mm Hg&#41;&#46; No significant associations were observed between lung function and hemodynamic parameters&#46; Mean age in the toxic oil syndrome group was lower &#40;33&#46;7 &#91;11&#46;4&#93; years&#41;&#44; and these patients had higher mean scores on the New York Heart Association scale &#40;3&#46;3 &#91;0&#46;5&#93;&#41; and for pulmonary vascular resistance &#40;20&#46;3 &#91;8&#46;1&#93; kPa&#183;L<span class="elsevierStyleSup">-1</span>&#183;s&#41;&#46;</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p class="elsevierStyleSimplePara elsevierViewall">Lung function was studied in a series of 120 patients with pulmonary arterial hypertension &#40;Evian&#47; Venice groups 1 and 4&#41;&#44; 30 of whom had toxic oil syndrome&#46; No significant associations were found between lung function and hemodynamic parameters&#46;</p>"
      ]
      "es" => array:1 [
        "resumen" => "<span class="elsevierStyleSectionTitle">Objetivo</span><p class="elsevierStyleSimplePara elsevierViewall">El objetivo principal es la descripci&#243;n de los hallazgos funcionales respiratorios en una serie de 120 pacientes con hipertensi&#243;n arterial pulmonar &#40;HAP&#41;&#44; y el objetivo secundario es su comparaci&#243;n con los datos hemodin&#225;micos&#46;</p> <span class="elsevierStyleSectionTitle">Pacientes y m&#233;todos</span><p class="elsevierStyleSimplePara elsevierViewall">Estudio descriptivo de la funci&#243;n pulmonar de los 120 casos con HAP estable&#44; de los grupos 1 y 4 de Evian&#47;Venecia&#44; estudiados hasta enero de 2002 en el grupo de trabajo de Hipertensi&#243;n Pulmonar y Trasplante de Pulm&#243;n del Servicio de Cardiolog&#237;a del Hospital Universitario 12 de Octubre de Madrid&#46; Los datos de 47 pacientes se recogieron retrospectivamente desde 1981 a 1995&#44; y de forma prospectiva en los 73 restantes&#46; Se incluyeron casos de hipertensi&#243;n arterial idiop&#225;tica y de la asociada a colagenosis&#44; tromboembolia pulmonar cr&#243;nica&#44; <span class="elsevierStyleItalic">shunt</span> card&#237;aco y&#44; en 30 casos&#44; a s&#237;ndrome de aceite t&#243;xico &#40;SAT&#41;&#46;</p> <span class="elsevierStyleSectionTitle">Resultados</span><p class="elsevierStyleSimplePara elsevierViewall">En el conjunto del grupo la capacidad vital&#44; el volumen espiratorio forzado en el primer segundo y la capacidad pulmonar total fueron normales&#59; los valores medios mostraron un factor de transferencia bajo &#40;media &#177; desvia-ci&#243;n est&#225;ndar&#58; 67&#44;6 &#177; 23&#44;2&#41;&#44; e hipoxemia moderada &#40;65&#44;8 &#177; 15&#44;4 mmHg&#41;&#46; No se observaron asociaciones significativas entre los par&#225;metros funcionales pulmonares y los hemodin&#225;micos&#46; El grupo con SAT ten&#237;a la edad m&#225;s baja &#40;33&#44;7 &#177; 11&#44;4 a&#241;os&#41;&#44; junto a los valores medios m&#225;s altos en la escala de la New York Heart Association &#40;3&#44;3 &#177; 0&#44;5&#41; y de resistencias vasculares pulmonares &#40;20&#44;3 &#177; 8&#44;1 kPa&#183;l<span class="elsevierStyleSup">-1</span>&#183;s&#41;&#46;</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p class="elsevierStyleSimplePara elsevierViewall">En este trabajo se estudia la funci&#243;n pulmonar en una serie de 120 pacientes con HAP&#44; de los grupos 1 y 4 de Evian&#47;Venecia&#44; entre los que se incluy&#243; a 30 casos con SAT&#46; No se han encontrado asociaciones significativas entre los valores funcionales respiratorios y los hemodin&#225;micos&#46;</p>"
      ]
    ]
    "NotaPie" => array:1 [
      0 => array:1 [
        "nota" => "<p class="elsevierStyleNotepara">This work was sponsored by RTIC CO3&#47;011</p>"
      ]
    ]
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ISSN: 15792129
Original language: English
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2013 December 34 13 47
2013 November 54 7 61
2013 October 45 16 61
2013 September 38 15 53
2013 August 47 11 58
2013 July 42 17 59
2013 June 45 13 58
2013 May 41 11 52
2013 April 35 11 46
2013 March 7 1 8
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Archivos de Bronconeumología

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