Original Articles
Endoscopic Treatment of Central Airway Stenosis: Five Years' Experience
A. Cosano Povedano, L. Muñoz Cabrera, F.J. Cosano Povedano
, J. Rubio Sánchez, N. Pascual Martínez, A. Escribano Dueñas
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andr539@separ.es
Correspondence: Dr. A. Cosano Povedano. Servicio de Neumología. Hospital Universitario Reina Sofía. Avda. Menéndez Pidal, s/n. 14004 Córdoba. España
Correspondence: Dr. A. Cosano Povedano. Servicio de Neumología. Hospital Universitario Reina Sofía. Avda. Menéndez Pidal, s/n. 14004 Córdoba. España
Servicio de Neumología, Hospital Universitario Reina Sofía, Córdoba, Spain
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Borderías Clau, M. Zabaleta Murguionda, J.A. Riesco Miranda, C. Pellicer Ciscar, J. R. Hernández Hernández, T. Carrillo Díaz, G. Lumbreras García" "autores" => array:7 [ 0 => array:3 [ "preGrado" => "Dr." "nombre" => "L." "apellidos" => "Borderías Clau" ] 1 => array:2 [ "nombre" => "M." "apellidos" => "Zabaleta Murguionda" ] 2 => array:2 [ "nombre" => "J.A." "apellidos" => "Riesco Miranda" ] 3 => array:2 [ "nombre" => "C." "apellidos" => "Pellicer Ciscar" ] 4 => array:2 [ "nombre" => "J." "apellidos" => "R. Hernández Hernández" ] 5 => array:2 [ "nombre" => "T." "apellidos" => "Carrillo Díaz" ] 6 => array:2 [ "nombre" => "G." "apellidos" => "Lumbreras García" ] ] ] ] ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1579212906602395?idApp=UINPBA00003Z" "url" => "/15792129/0000004100000006/v1_201305150218/S1579212906602395/v1_201305150218/en/main.assets" ] "en" => array:14 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Original Articles</span>" "titulo" => "Endoscopic Treatment of Central Airway Stenosis: Five Years' Experience" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "322" "paginaFinal" => "327" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "A. Cosano Povedano, L. Muñoz Cabrera, F.J. Cosano Povedano, J. Rubio Sánchez, N. Pascual Martínez, A. Escribano Dueñas" "autores" => array:6 [ 0 => array:2 [ "nombre" => "A." "apellidos" => "Cosano Povedano" ] 1 => array:2 [ "nombre" => "L." "apellidos" => "Muñoz Cabrera" ] 2 => array:5 [ "preGrado" => "Dr." "nombre" => "F.J." "apellidos" => "Cosano Povedano" "email" => array:1 [ 0 => "andr539@separ.es" ] "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor1" ] ] ] 3 => array:2 [ "nombre" => "J." "apellidos" => "Rubio Sánchez" ] 4 => array:2 [ "nombre" => "N." "apellidos" => "Pascual Martínez" ] 5 => array:2 [ "nombre" => "A." "apellidos" => "Escribano Dueñas" ] ] "afiliaciones" => array:1 [ 0 => array:1 [ "entidad" => "Servicio de Neumología, Hospital Universitario Reina Sofía, Córdoba, Spain" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor1" "etiqueta" => "*" "correspondencia" => "Correspondence: Dr. A. Cosano Povedano. Servicio de Neumología. Hospital Universitario Reina Sofía. Avda. Menéndez Pidal, s/n. 14004 Córdoba. España" ] ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2003-10-01" "fechaAceptado" => "2004-10-05" "PalabrasClave" => array:2 [ "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key words" "identificador" => "xpalclavsec154088" "palabras" => array:3 [ 0 => "Airways" 1 => "Interventional bronchoscopy" 2 => "Stents" ] ] ] "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec154089" "palabras" => array:3 [ 0 => "Vías aéreas" 1 => "Broncoscopia intervencionista" 2 => "Prótesis" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "en" => array:1 [ "resumen" => "<span class="elsevierStyleSectionTitle">Objective</span><p class="elsevierStyleSimplePara elsevierViewall">TO describe our experience with interventional bronchoscopy in the treatment of central airway stenosis.</p> <span class="elsevierStyleSectionTitle">Patients and methods</span><p class="elsevierStyleSimplePara elsevierViewall">We reviewed patient records and bronchoscopic findings. Clinical data, findings from computed tomography, techniques performed, complications, and results were recorded.</p> <span class="elsevierStyleSectionTitle">Results</span><p class="elsevierStyleSimplePara elsevierViewall">One-hundred and thirty-six patients (90 males and 46 females) were treated. The mean (SD) age was 57 (7) years (range, 3-81). A total of 320 therapeutic interventions were performed: 145 laser treatments, 33 balloon or mechanical dilatations, 26 electrocauterizations, and 116 stent insertions. Pathogenesis varied: in 64 (47%) patients, the stenosis was caused by a tumor (48 were bronchopulmonary and 16 nonpulmonary); in 72 (53%) patients, stenosis was secondary to a nontumor-related process, of which the most common was prolonged intubation (42% of these cases). Central airway patency was achieved in 92% (59/64) of the tumor-related stenoses and 96% (69/72) of those unrelated to tumors. Improvement in dyspnea was observed in 96% of all patients. Two deaths (due to hemoptysis and to acute myocardial infarction) occurred in the first week, for a 1.4% mortality rate. The most common complications were stent migration (8%; 9/116 cases) and the formation of granulomas (9%; 11/116).</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p class="elsevierStyleSimplePara elsevierViewall">Interventional bronchoscopy is an effective technique to resolve life-threatening obstructions of the central airways. Dyspnea improves immediately and there is no significant morbidity or mortality.</p>" ] "es" => array:1 [ "resumen" => "<span class="elsevierStyleSectionTitle">Objetivo</span><p class="elsevierStyleSimplePara elsevierViewall">Describir nuestra experiencia en estenosis de la vía aérea principal (VAP) tratadas mediante broncoscopia intervencionista.</p> <span class="elsevierStyleSectionTitle">Pacientes y métodos</span><p class="elsevierStyleSimplePara elsevierViewall">Se han revisado las historias clíni-cas e informes de broncoscopia y se han registrado los datos clínicos, informe de tomografía axial computarizada, técnicas realizadas, complicaciones y resultados.</p> <span class="elsevierStyleSectionTitle">Resultados</span><p class="elsevierStyleSimplePara elsevierViewall">Se trató a 136 pacientes (90 varones y 46 mujeres), con una edad media ± desviación estándar de 57 ± 7 años (rango: 3-81), en quienes se realizaron 320 procedimientos terapéuticos, que incluyeron 145 tratamientos con láser, 33 dilataciones con balón o mecánicas, 26 tratamientos mediante electrocauterio y la colocación de 116 prótesis. La etiología de la estenosis fue diversa: hubo 64 (47%) de causa tumoral (48 de origen broncopulmonar y 16 tumores extrapulmonares), mientras que en 72 pacientes (53%) la estenosis fue secundaria a una enfermedad no tumoral; de éstas, la causada por intubación prolongada fue la más frecuente (el 42% de los casos).</p><p class="elsevierStyleSimplePara elsevierViewall">La permeabilidad de la VAP se logró en el 92% (59/64) de las estenosis de etiología tumoral y en el 96 % de las no tumorales (69/72), y se observó mejoría de la disnea en el 96% de todos los pacientes. En la primera semana hubo 2 fallecimientos (por hemoptisis e infarto agudo de miocardio), lo que representa una mortalidad del 1,4%. Las complicaciones más frecuentes fueron la migración de prótesis en un 8% (9/116) y en un 9% la formación de granulomas (11/116).</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p class="elsevierStyleSimplePara elsevierViewall">La broncoscopia intervencionista es una técnica eficaz para resolver las situaciones de riesgo vital de la VAP, con mejoría inmediata de la disnea y sin morbimortalidad significativa.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "REFERENCES" "seccion" => array:1 [ 0 => array:1 [ "bibliografiaReferencia" => array:23 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Broncoscopia rígida" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "P Díaz Jiménez" 1 => "AN Rodríguez" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "LibroEditado" => array:4 [ "titulo" => "Neumología intervencionista" "paginaInicial" => "1" "paginaFinal" => "18" "serieFecha" => "2000" ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib2" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Interventional pulmonology" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "LM Seijo" 1 => "DH Sterman" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1056/NEJM200103083441007" "Revista" => array:6 [ "tituloSerie" => "N Engl J Med" "fecha" => "2001" "volumen" => "344" "paginaInicial" => "740" "paginaFinal" => "748" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11236779" "web" => "Medline" ] ] ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib3" "etiqueta" => "3" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Section on respiratory endoscopy of the German Society of Pulmonology. 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| Year/Month | Html | Total | |
|---|---|---|---|
| 2024 November | 4 | 2 | 6 |
| 2024 October | 23 | 16 | 39 |
| 2024 September | 25 | 13 | 38 |
| 2024 August | 46 | 29 | 75 |
| 2024 July | 21 | 18 | 39 |
| 2024 June | 26 | 23 | 49 |
| 2024 May | 29 | 28 | 57 |
| 2024 April | 15 | 19 | 34 |
| 2024 March | 18 | 14 | 32 |
| 2024 February | 20 | 23 | 43 |
| 2023 November | 0 | 2 | 2 |
| 2023 March | 1 | 2 | 3 |
| 2023 February | 18 | 22 | 40 |
| 2023 January | 17 | 30 | 47 |
| 2022 December | 18 | 26 | 44 |
| 2022 November | 19 | 27 | 46 |
| 2022 October | 19 | 40 | 59 |
| 2022 September | 12 | 23 | 35 |
| 2022 August | 19 | 31 | 50 |
| 2022 July | 25 | 43 | 68 |
| 2022 June | 18 | 28 | 46 |
| 2022 May | 18 | 38 | 56 |
| 2022 April | 14 | 35 | 49 |
| 2022 March | 17 | 35 | 52 |
| 2022 February | 16 | 39 | 55 |
| 2022 January | 15 | 36 | 51 |
| 2021 December | 13 | 36 | 49 |
| 2021 November | 16 | 51 | 67 |
| 2021 October | 25 | 52 | 77 |
| 2021 September | 19 | 44 | 63 |
| 2021 August | 12 | 25 | 37 |
| 2021 July | 14 | 25 | 39 |
| 2021 June | 14 | 35 | 49 |
| 2021 May | 11 | 27 | 38 |
| 2021 April | 28 | 66 | 94 |
| 2021 March | 18 | 27 | 45 |
| 2021 February | 11 | 30 | 41 |
| 2021 January | 12 | 15 | 27 |
| 2020 December | 13 | 25 | 38 |
| 2020 November | 4 | 14 | 18 |
| 2020 October | 14 | 6 | 20 |
| 2020 September | 4 | 8 | 12 |
| 2020 August | 14 | 11 | 25 |
| 2020 July | 13 | 24 | 37 |
| 2020 June | 7 | 8 | 15 |
| 2020 May | 16 | 16 | 32 |
| 2020 April | 10 | 11 | 21 |
| 2020 March | 12 | 18 | 30 |
| 2020 February | 10 | 21 | 31 |
| 2020 January | 21 | 22 | 43 |
| 2019 December | 17 | 19 | 36 |
| 2019 November | 10 | 19 | 29 |
| 2019 October | 9 | 8 | 17 |
| 2019 September | 5 | 14 | 19 |
| 2019 August | 14 | 14 | 28 |
| 2019 July | 11 | 25 | 36 |
| 2019 June | 10 | 15 | 25 |
| 2019 May | 21 | 14 | 35 |
| 2019 April | 40 | 17 | 57 |
| 2019 March | 17 | 16 | 33 |
| 2019 February | 21 | 16 | 37 |
| 2019 January | 13 | 5 | 18 |
| 2018 December | 10 | 18 | 28 |
| 2018 November | 15 | 15 | 30 |
| 2018 October | 12 | 15 | 27 |
| 2018 September | 10 | 9 | 19 |
| 2018 May | 1 | 1 | 2 |
| 2018 April | 9 | 5 | 14 |
| 2018 March | 2 | 3 | 5 |
| 2018 February | 7 | 8 | 15 |
| 2018 January | 6 | 9 | 15 |
| 2017 December | 4 | 7 | 11 |
| 2017 November | 3 | 8 | 11 |
| 2017 October | 8 | 8 | 16 |
| 2017 September | 3 | 8 | 11 |
| 2017 August | 5 | 15 | 20 |
| 2017 July | 2 | 7 | 9 |
| 2017 June | 6 | 8 | 14 |
| 2017 May | 10 | 7 | 17 |
| 2017 April | 3 | 3 | 6 |
| 2017 March | 7 | 11 | 18 |
| 2017 February | 4 | 3 | 7 |
| 2017 January | 4 | 5 | 9 |
| 2016 December | 8 | 7 | 15 |
| 2016 November | 15 | 10 | 25 |
| 2016 October | 15 | 9 | 24 |
| 2016 September | 13 | 4 | 17 |
| 2016 August | 18 | 4 | 22 |
| 2016 July | 6 | 5 | 11 |
| 2016 March | 2 | 0 | 2 |
| 2015 December | 1 | 0 | 1 |
| 2015 October | 62 | 1 | 63 |
| 2015 September | 46 | 6 | 52 |
| 2015 August | 34 | 13 | 47 |
| 2015 July | 56 | 6 | 62 |
| 2015 June | 37 | 7 | 44 |
| 2015 May | 42 | 9 | 51 |
| 2015 April | 53 | 19 | 72 |
| 2015 March | 46 | 10 | 56 |
| 2015 February | 29 | 10 | 39 |
| 2015 January | 43 | 10 | 53 |
| 2014 December | 42 | 7 | 49 |
| 2014 November | 36 | 6 | 42 |
| 2014 October | 41 | 15 | 56 |
| 2014 September | 38 | 13 | 51 |
| 2014 August | 48 | 15 | 63 |
| 2014 July | 58 | 9 | 67 |
| 2014 June | 47 | 18 | 65 |
| 2014 May | 59 | 12 | 71 |
| 2014 April | 57 | 14 | 71 |
| 2014 March | 77 | 12 | 89 |
| 2014 February | 63 | 12 | 75 |
| 2014 January | 32 | 13 | 45 |
| 2013 December | 48 | 14 | 62 |
| 2013 November | 48 | 15 | 63 |
| 2013 October | 41 | 9 | 50 |
| 2013 September | 44 | 8 | 52 |
| 2013 August | 46 | 17 | 63 |
| 2013 July | 38 | 11 | 49 |
| 2013 June | 38 | 10 | 48 |
| 2013 May | 29 | 3 | 32 |
| 2013 April | 25 | 8 | 33 |
| 2013 March | 10 | 2 | 12 |
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