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Effect of Different Bronchial Washing Sequences on Diagnostic Yield in Endoscopically Visible Lung Cancer
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Fernández-Villar. Joaquín Costa, 60, 6.° C. 36004 Pontevedra. España" ] ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2005-09-12" "fechaAceptado" => "2005-11-08" "PalabrasClave" => array:2 [ "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key words" "identificador" => "xpalclavsec154398" "palabras" => array:5 [ 0 => "Fiberoptic bronchoscopy" 1 => "Lung cancer" 2 => "Endobronchial lesion" 3 => "Bronchial lavage fluid" 4 => "Cytology" ] ] ] "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec154397" "palabras" => array:5 [ 0 => "Fibrobroncoscopia" 1 => "Carcinoma broncogénico" 2 => "Lesión endobronquial" 3 => "Aspirado bronquial" 4 => "Citología" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "en" => array:1 [ "resumen" => "<span class="elsevierStyleSectionTitle">Objective</span><p class="elsevierStyleSimplePara elsevierViewall">Aspiration of bronchial wash fluid is commonly used in conjunction with brushing and forceps biopsy to diagnose endoscopically visible lung cancer. However, the optimal sequence of these procedures is subject to debate. The objective of this study was to determine if the order in which bronchial washing is performed relative to bronchial brushing and forceps biopsy has any effect on the diagnostic yield.</p> <span class="elsevierStyleSectionTitle">Patients and methods</span><p class="elsevierStyleSimplePara elsevierViewall">A prospective, cross-sectional study was carried out on patients with endoscopically visible lung cancer who underwent video-assisted fiberoptic bronchoscopy for diagnostic purposes. Aspiration of bronchial wash fluid was performed on all patients both before and after bronchial brushing and forceps biopsy. The results were analyzed separately for each type of endobronchial lesion and for both together.</p> <span class="elsevierStyleSectionTitle">Results</span><p class="elsevierStyleSimplePara elsevierViewall">The study included 75 patients, with a mean age of 63.3 years; 81% were men. Bronchoscopy was diagnostic in 71 (94.7%) cases. Findings from bronchial washing fluid were positive in 40 (53.3%) patients when washing was performed prior to brushing and forceps biopsy; when washing was performed after these procedures, findings were positive in 43 (57.3%) patients (<span class="elsevierStyleItalic">P</span>=.6). The combined diagnostic yield of washing before and after brushing and forceps biopsy was 69.3%, a significantly better result than either washing before (<span class="elsevierStyleItalic">P</span>=.001) or after (<span class="elsevierStyleItalic">P</span>=.004) the other sampling techniques. In cases where findings from washing done after brushing and forceps biopsy were negative (14 of 32, 43.7%), blood in the aspirated sample interfered with cytology. In comparison, when washing was performed prior to brushing and biopsy, that problem arose in only 3 of the 35 cases (8.5%) (<span class="elsevierStyleItalic">P</span>=.002).</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p class="elsevierStyleSimplePara elsevierViewall">The order in which bronchial washing is performed in relation to other sampling techniques for diagnosing bronchial tumors does not influence the diagnostic yield. This is probably because the aspirated fluid sample is more likely to contain excessive blood when washing is performed after brushing and forceps biopsy. However, the diagnostic yield can be significantly increased by combining the findings from bronchial washings performed both before and after other sample collection procedures.</p>" ] "es" => array:1 [ "resumen" => "<span class="elsevierStyleSectionTitle">Objetivo</span><p class="elsevierStyleSimplePara elsevierViewall">Además del cepillado y de la biopsia bronquiales, el aspirado bronquial (AB) es una técnica utilizada habitualmente en el diagnóstico del cáncer de pulmón endoscópicamente visible. Existe controversia sobre el momento adecuado para su realización. El objetivo del presente estudio ha sido evaluar si el momento de la realización del AB puede influir en el rendimiento diagnóstico.</p> <span class="elsevierStyleSectionTitle">Pacientes y métodos</span><p class="elsevierStyleSimplePara elsevierViewall">Se ha llevado a cabo un estudio transversal prospectivo, en el que se incluyó a pacientes con carcinomas broncogénicos endoscópicamente visibles a los que se hizo una videofibrobroncoscopia con fines diagnósticos. A todos se les realizaba AB previo y tras el cepillado y la biopsia bronquiales. El resultado se analizó de forma global y para cada tipo de lesión endobronquial.</p> <span class="elsevierStyleSectionTitle">Resultados</span><p class="elsevierStyleSimplePara elsevierViewall">Se incluyó a 75 pacientes con una edad media de 63,3 años siendo el 81 % varones. La broncoscopia fue diagnóstica en 71 (94,7%). El AB previo fue positivo en 40 pacientes (53,3%) y el posterior en 43 (57,3%) (p = 0,6). La rentabilidad conjunta de ambos fue del 69,3%, significativamente superior a la del AB previo (p = 0,001) y la del AB posterior (p = 0,004) por separado. En el 43,7% de los casos en que el AB posterior fue negativo, la valoración citológica se vio dificultada por ser muy hemática, frente al 8,5% de los AB previos negativos (p = 0,002).</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p class="elsevierStyleSimplePara elsevierViewall">El orden de la realización del AB en el diagnóstico de neoplasias bronquiales no influye en el rendimiento diagnóstico, probablemente por la mayor frecuencia de AB hemorrágicos que se producen cuando el AB se realiza tras el cepillado y la biopsia bronquiales. El estudio conjunto de ambos AB incrementa significativamente el rendimiento diagnóstico de la técnica.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "REFERENCES" "seccion" => array:1 [ 0 => array:1 [ "bibliografiaReferencia" => array:24 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Bronchoscopy and needle biopsy techniques for diagnosis and staging of lung cancer" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "P Mazzone" 1 => "P Jain" 2 => "AC Arroliga" 3 => "RA Matthay" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Clin Chest Med" "fecha" => "2002" "volumen" => "23" "paginaInicial" => "137" "paginaFinal" => "158" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11901908" "web" => "Medline" ] ] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib2" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Fibrobroncoscopia en el cáncer de pulmón: relación entre radiología, endoscopia, histología y rendimiento diagnóstico en una serie de 1.801 casos" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "E Martínez Moragón" 1 => "J Aparicio Urtasun" 2 => "J Sanchís Aldás" 3 => "A de Diego Damiá" 4 => "M Martínez Francés" 5 => "E Cases Viedma" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Arch Bronconeumol" "fecha" => "1994" "volumen" => "30" "paginaInicial" => "291" "paginaFinal" => "296" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8087388" "web" => "Medline" ] ] ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib3" "etiqueta" => "3" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Value of washing and brushings of fiberoptic bronchoscopy in the diagnosis of lung cancer" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "VHF Mark" 1 => "ID Johnston" 2 => "MR Hetzel" 3 => "C Grubb" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Thorax" "fecha" => "1990" "volumen" => "45" "paginaInicial" => "373" "paginaFinal" => "376" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2200159" "web" => "Medline" ] ] ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib4" "etiqueta" => "4" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Cost-effectiveness of collecting routine cytologic specimens during fiberoptic bronchoscopy for endoscopically visible lung tumor" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "JA Govert" 1 => "JM Kopita" 2 => "D Matchar" 3 => "PS Kussin" 4 => "WH Samuelson" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Chest" "fecha" => "1996" "volumen" => "109" "paginaInicial" => "451" "paginaFinal" => "456" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8620721" "web" => "Medline" ] ] ] ] ] ] ] ] 4 => array:3 [ "identificador" => "bib5" "etiqueta" => "5" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Usefulness of various diagnostic techniques during fiberoptic bronchoscopy of endoscopically visible lung cancer: should cytologic examinations be performed routinely?" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "E Karahalli" 1 => "A Yilmaz" 2 => "H Türker" 3 => "K Özvaran" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Respiration" "fecha" => "2001" "volumen" => "68" "paginaInicial" => "611" "paginaFinal" => "614" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11786717" "web" => "Medline" ] ] ] ] ] ] ] ] 5 => array:3 [ "identificador" => "bib6" "etiqueta" => "6" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Normativa actualizada sobre diagnóstico y estadificación del carcinoma broncogénico" "autores" => array:1 [ 0 => array:3 [ "colaboracion" => "Grupo de Trabajo SEPAR" "etal" => false "autores" => array:4 [ 0 => "R Ramí" 1 => "JL Duque" 2 => "JR Hernández" 3 => "J Sánchez de Cos" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Arch Bronconeumol" "fecha" => "1998" "volumen" => "34" "paginaInicial" => "437" "paginaFinal" => "452" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9842457" "web" => "Medline" ] ] ] ] ] ] ] ] 6 => array:3 [ "identificador" => "bib7" "etiqueta" => "7" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Performance characteristics of different modalities for diagnosis of suspected lung cancer" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "G Schreiber" 1 => "DC McCrory" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Chest" "fecha" => "2003" "volumen" => "123" "numero" => "Suppl" "paginaInicial" => "115" "paginaFinal" => "128" ] ] ] ] ] ] 7 => array:3 [ "identificador" => "bib8" "etiqueta" => "8" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "British Thoracic Society guidelines on diagnostic flexible bronchoscopy" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "British Thoracic Society" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ "tituloSerie" => "Thorax" "fecha" => "2001" "volumen" => "56" "numero" => "Suppl I" "paginaInicial" => "1" "paginaFinal" => "21" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11120894" "web" => "Medline" ] ] ] ] ] ] ] ] 8 => array:3 [ "identificador" => "bib9" "etiqueta" => "9" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Broncoscopia general" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "J Castella" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "LibroEditado" => array:5 [ "titulo" => "Medicina respiratoria" "paginaInicial" => "409" "paginaFinal" => "427" "edicion" => "2nd ed." "serieFecha" => "2005" ] ] ] ] ] ] 9 => array:3 [ "identificador" => "bib10" "etiqueta" => "10" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Bronchoscopic specimen collection: is there a proper order of sequence" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "UBS Prakash" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "J Bronchol" "fecha" => "2002" "volumen" => "9" "paginaInicial" => "269" "paginaFinal" => "271" ] ] ] ] ] ] 10 => array:3 [ "identificador" => "bib11" "etiqueta" => "11" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Basic techniques in flexible bronchoscopy" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "FYW Lee" 1 => "AC Metha" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "LibroEditado" => array:4 [ "titulo" => "Flexible bronchoscopy" "paginaInicial" => "95" "paginaFinal" => "118" "serieFecha" => "1995" ] ] ] ] ] ] 11 => array:3 [ "identificador" => "bib12" "etiqueta" => "12" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Noninvasive bronchoscopic specimens in the diagnosis of lung cancer" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "D Yick" 1 => "N Kamangar" 2 => "JM Wallace" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "J Bronchol" "fecha" => "2001" "volumen" => "8" "paginaInicial" => "301" "paginaFinal" => "308" ] ] ] ] ] ] 12 => array:3 [ "identificador" => "bib13" "etiqueta" => "13" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Fiberoptic bronchoscopy: comparison of procedures used in the diagnosis of lung cancer" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "BA Chaudhary" 1 => "K Yoneda" 2 => "NK Burki" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Thorac Cardiovasc Surg" "fecha" => "1978" "volumen" => "76" "paginaInicial" => "33" "paginaFinal" => "37" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/661364" "web" => "Medline" ] ] ] ] ] ] ] ] 13 => array:3 [ "identificador" => "bib14" "etiqueta" => "14" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Wash or not to wash, brush or not to brush. That is the question" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "AC Metha" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "J Bronchol" "fecha" => "2001" "volumen" => "7" "paginaInicial" => "293" "paginaFinal" => "294" ] ] ] ] ] ] 14 => array:3 [ "identificador" => "bib15" "etiqueta" => "15" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Guidelines of the Papanicolaou Society of Cytologic specimens obtained from the respiratory tract" "autores" => array:1 [ 0 => array:2 [ "colaboracion" => "Papanicolaou Society of Cytopathology Task Force on Standards Practice" "etal" => false ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Diagn Cytopathol" "fecha" => "1999" "volumen" => "21" "paginaInicial" => "61" "paginaFinal" => "69" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10405813" "web" => "Medline" ] ] ] ] ] ] ] ] 15 => array:3 [ "identificador" => "bib16" "etiqueta" => "16" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Timing of collecting bronchoscopic cytologic specimens in endobronchial malignant neoplasms" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "M Yigla" 1 => "D Nagiv" 2 => "A Solomonov" 3 => "E Malderger" 4 => "O Ben-Izhak" 5 => "AE Rubin" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Bronchol" "fecha" => "2002" "volumen" => "9" "paginaInicial" => "272" "paginaFinal" => "275" "itemHostRev" => array:3 [ "pii" => "S0268960X10000597" "estado" => "S300" "issn" => "0268960X" ] ] ] ] ] ] ] 16 => array:3 [ "identificador" => "bib17" "etiqueta" => "17" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "A prospective study of the timing and cost-effectiveness of bronchial washing during bronchoscopy for pulmonary malignant tumors" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "MA van der Drift" 1 => "G van der Wilt" 2 => "FBJM Thumissen" 3 => "JP Janssen" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1378/chest.128.1.394" "Revista" => array:6 [ "tituloSerie" => "Chest" "fecha" => "2005" "volumen" => "128" "paginaInicial" => "394" "paginaFinal" => "400" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16002962" "web" => "Medline" ] ] ] ] ] ] ] ] 17 => array:3 [ "identificador" => "bib18" "etiqueta" => "18" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Timing of bronchial washing at fibrebronchoscopy improves the diagnostic rate of primary bronchial carcinoma" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "NJ Raymond" 1 => "S McLeod" 2 => "PE Thornley" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Thorax" "fecha" => "1991" "volumen" => "46" "numero" => "Suppl" "paginaInicial" => "289" ] ] ] ] ] ] 18 => array:3 [ "identificador" => "bib19" "etiqueta" => "19" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Bronchial washings: when should we do them?" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "NA Scriven" 1 => "JT MacFarlane" 2 => "CA Clelland" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Thorax" "fecha" => "1999" "volumen" => "54" "numero" => "Suppl" "paginaInicial" => "84" ] ] ] ] ] ] 19 => array:3 [ "identificador" => "bib20" "etiqueta" => "20" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Does the sequence of sample collection alter the yield of fiberoptic bronchoscopy in patients with suspected malignancy" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "VJ Test" 1 => "WG Petersen" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Chest" "fecha" => "2003" "volumen" => "124" "numero" => "Suppl" "paginaInicial" => "78" ] ] ] ] ] ] 20 => array:3 [ "identificador" => "bib21" "etiqueta" => "21" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The effect of altering the sequence order of saline washing in the bronchoscopic diagnosis of lung cancer. Abstract of 2005 Annual Scientific Meeting of the Thoracic Society of Australia and New Zealand. Accessed on August 28, 2005" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "G Eather" 1 => "R Nickels" 2 => "J Feenstra" 3 => "J Armstrong" 4 => "M Turner" 5 => "L Garske" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "WWW" => array:1 [ "link" => "Available from: http://www.thoracic.org.au/asma2005abstractslist.php" ] ] ] ] ] ] 21 => array:3 [ "identificador" => "bib22" "etiqueta" => "22" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Punción transbronquial aspirativa" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "C Disdier" 1 => "F Rodríguez de Castro" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Arch Bronconeumol" "fecha" => "2000" "volumen" => "36" "paginaInicial" => "580" "paginaFinal" => "593" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11149202" "web" => "Medline" ] ] ] ] ] ] ] ] 22 => array:3 [ "identificador" => "bib23" "etiqueta" => "23" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Punción transbronquial en el carcinoma broncogénico con lesión visible: rendimiento y coste económico" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "JA Gullón" 1 => "R Fernández" 2 => "A Medina" 3 => "G Rubinos" 4 => "I Suárez" 5 => "C Ramos" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Arch Bronconeumol" "fecha" => "2003" "volumen" => "39" "paginaInicial" => "496" "paginaFinal" => "500" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/14588202" "web" => "Medline" ] ] ] ] ] ] ] ] 23 => array:3 [ "identificador" => "bib24" "etiqueta" => "24" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Evaluation of the cellular sample" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "JR Goellner" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "LibroEditado" => array:5 [ "titulo" => "Comprehensive cytopathology" "paginaInicial" => "69" "paginaFinal" => "74" "edicion" => "2nd ed." "serieFecha" => "1997" ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/15792129/0000004200000006/v1_201305150246/S1579212906601432/v1_201305150246/en/main.assets" "Apartado" => null "PDF" => "https://static.elsevier.es/multimedia/15792129/0000004200000006/v1_201305150246/S1579212906601432/v1_201305150246/en/main.pdf?idApp=UINPBA00003Z&text.app=https://archbronconeumol.org/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1579212906601432?idApp=UINPBA00003Z" ]
| Year/Month | Html | Total | |
|---|---|---|---|
| 2024 November | 5 | 6 | 11 |
| 2024 October | 53 | 16 | 69 |
| 2024 September | 45 | 15 | 60 |
| 2024 August | 60 | 35 | 95 |
| 2024 July | 35 | 24 | 59 |
| 2024 June | 51 | 29 | 80 |
| 2024 May | 50 | 40 | 90 |
| 2024 April | 23 | 25 | 48 |
| 2024 March | 18 | 15 | 33 |
| 2024 February | 18 | 22 | 40 |
| 2024 January | 0 | 1 | 1 |
| 2023 March | 2 | 3 | 5 |
| 2023 February | 16 | 22 | 38 |
| 2023 January | 18 | 32 | 50 |
| 2022 December | 20 | 36 | 56 |
| 2022 November | 19 | 18 | 37 |
| 2022 October | 19 | 39 | 58 |
| 2022 September | 18 | 27 | 45 |
| 2022 August | 18 | 38 | 56 |
| 2022 July | 16 | 36 | 52 |
| 2022 June | 18 | 37 | 55 |
| 2022 May | 16 | 36 | 52 |
| 2022 April | 22 | 42 | 64 |
| 2022 March | 21 | 49 | 70 |
| 2022 February | 16 | 69 | 85 |
| 2022 January | 12 | 64 | 76 |
| 2021 December | 17 | 80 | 97 |
| 2021 November | 13 | 63 | 76 |
| 2021 October | 22 | 73 | 95 |
| 2021 September | 17 | 68 | 85 |
| 2021 August | 10 | 28 | 38 |
| 2021 July | 10 | 38 | 48 |
| 2021 June | 17 | 55 | 72 |
| 2021 May | 11 | 24 | 35 |
| 2021 April | 27 | 99 | 126 |
| 2021 March | 26 | 29 | 55 |
| 2021 February | 11 | 49 | 60 |
| 2021 January | 11 | 34 | 45 |
| 2020 December | 8 | 27 | 35 |
| 2020 November | 12 | 42 | 54 |
| 2020 October | 10 | 28 | 38 |
| 2020 September | 12 | 21 | 33 |
| 2020 August | 8 | 32 | 40 |
| 2020 July | 11 | 28 | 39 |
| 2020 June | 8 | 8 | 16 |
| 2020 May | 11 | 29 | 40 |
| 2020 April | 21 | 31 | 52 |
| 2020 March | 12 | 23 | 35 |
| 2020 February | 13 | 14 | 27 |
| 2020 January | 15 | 18 | 33 |
| 2019 December | 15 | 18 | 33 |
| 2019 November | 8 | 26 | 34 |
| 2019 October | 7 | 22 | 29 |
| 2019 September | 12 | 20 | 32 |
| 2019 August | 13 | 20 | 33 |
| 2019 July | 9 | 28 | 37 |
| 2019 June | 9 | 24 | 33 |
| 2019 May | 15 | 13 | 28 |
| 2019 April | 43 | 42 | 85 |
| 2019 March | 20 | 29 | 49 |
| 2019 February | 19 | 34 | 53 |
| 2019 January | 20 | 33 | 53 |
| 2018 December | 17 | 21 | 38 |
| 2018 November | 26 | 19 | 45 |
| 2018 October | 32 | 35 | 67 |
| 2018 September | 15 | 15 | 30 |
| 2018 May | 1 | 0 | 1 |
| 2018 April | 4 | 10 | 14 |
| 2018 March | 6 | 8 | 14 |
| 2018 February | 5 | 12 | 17 |
| 2018 January | 5 | 16 | 21 |
| 2017 December | 5 | 15 | 20 |
| 2017 November | 4 | 19 | 23 |
| 2017 October | 4 | 14 | 18 |
| 2017 September | 3 | 18 | 21 |
| 2017 August | 7 | 14 | 21 |
| 2017 July | 7 | 9 | 16 |
| 2017 June | 11 | 28 | 39 |
| 2017 May | 6 | 23 | 29 |
| 2017 April | 2 | 19 | 21 |
| 2017 March | 5 | 15 | 20 |
| 2017 February | 0 | 10 | 10 |
| 2017 January | 2 | 2 | 4 |
| 2016 December | 8 | 12 | 20 |
| 2016 November | 16 | 15 | 31 |
| 2016 October | 10 | 13 | 23 |
| 2016 September | 16 | 16 | 32 |
| 2016 August | 11 | 9 | 20 |
| 2016 July | 7 | 3 | 10 |
| 2016 March | 2 | 0 | 2 |
| 2015 December | 2 | 0 | 2 |
| 2015 October | 136 | 14 | 150 |
| 2015 September | 120 | 14 | 134 |
| 2015 August | 132 | 4 | 136 |
| 2015 July | 115 | 8 | 123 |
| 2015 June | 102 | 12 | 114 |
| 2015 May | 113 | 15 | 128 |
| 2015 April | 104 | 21 | 125 |
| 2015 March | 94 | 11 | 105 |
| 2015 February | 79 | 9 | 88 |
| 2015 January | 105 | 13 | 118 |
| 2014 December | 117 | 6 | 123 |
| 2014 November | 127 | 7 | 134 |
| 2014 October | 123 | 13 | 136 |
| 2014 September | 120 | 12 | 132 |
| 2014 August | 95 | 12 | 107 |
| 2014 July | 132 | 7 | 139 |
| 2014 June | 112 | 8 | 120 |
| 2014 May | 90 | 11 | 101 |
| 2014 April | 88 | 10 | 98 |
| 2014 March | 90 | 14 | 104 |
| 2014 February | 90 | 9 | 99 |
| 2014 January | 83 | 9 | 92 |
| 2013 December | 55 | 10 | 65 |
| 2013 November | 58 | 3 | 61 |
| 2013 October | 49 | 13 | 62 |
| 2013 September | 44 | 14 | 58 |
| 2013 August | 48 | 22 | 70 |
| 2013 July | 43 | 12 | 55 |
| 2013 June | 45 | 24 | 69 |
| 2013 May | 50 | 7 | 57 |
| 2013 April | 28 | 6 | 34 |
| 2013 March | 16 | 5 | 21 |
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