Case Reports
A Lung Transplant in a Woman With Bronchiolitis Obliterans Following an Allogenic Bone Marrow Transplant
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Furest, M. Marín, P. Escribano, M.A. Gómez, J. Cortina, R. Blanquer" "autores" => array:6 [ 0 => array:3 [ "preGrado" => "Dr." "nombre" => "I." "apellidos" => "Furest" ] 1 => array:2 [ "nombre" => "M." "apellidos" => "Marín" ] 2 => array:2 [ "nombre" => "P." "apellidos" => "Escribano" ] 3 => array:2 [ "nombre" => "M.A." "apellidos" => "Gómez" ] 4 => array:2 [ "nombre" => "J." "apellidos" => "Cortina" ] 5 => array:2 [ "nombre" => "R." 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"apellidos" => "Redel-Montero" "email" => array:1 [ 0 => "javierredel@msn.com" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor1" ] ] ] 1 => array:3 [ "nombre" => "F." "apellidos" => "Santos-Luna" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] ] ] 2 => array:3 [ "nombre" => "R." "apellidos" => "Lama-Martínez" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] ] ] 3 => array:3 [ "nombre" => "J." "apellidos" => "Algar-Algar" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff2" ] ] ] 4 => array:3 [ "nombre" => "A." "apellidos" => "Salvatierra-Velázquez" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff2" ] ] ] 5 => array:3 [ "nombre" => "A." "apellidos" => "Álvarez-Kindelán" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff2" ] ] ] ] "afiliaciones" => array:2 [ 0 => array:3 [ "entidad" => "Unidad de Trasplante Pulmonar, Servicio de Neumología, Hospital Universitario Reina Sofía, Córdoba, Spain" "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] 1 => array:3 [ "entidad" => "Unidad de Trasplante Pulmonar, Servicio de Cirugía Torácica, Hospital Universitario Reina Sofía, Córdoba, Spain" "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff2" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor1" "etiqueta" => "*" "correspondencia" => "Correspondence: Dr. J. Redel-Montero. Avda. Arruzafilla, 7, portal 4, 2.° I. 14011 Córdoba. España" ] ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2005-04-28" "fechaAceptado" => "2005-05-24" "PalabrasClave" => array:2 [ "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key words" "identificador" => "xpalclavsec154289" "palabras" => array:4 [ 0 => "Bone marrow aplasia" 1 => "Bone marrow transplantation" 2 => "Bronchiolitis obliterans" 3 => "Lung transplant" ] ] ] "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec154290" "palabras" => array:4 [ 0 => "Aplasia medular" 1 => "Trasplante de médula ósea" 2 => "Bronquiolitis obliterante" 3 => "Trasplante pulmonar" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "en" => array:1 [ "resumen" => "<p class="elsevierStyleSimplePara elsevierViewall">Graft-versus-host disease is a major complication for bone marrow transplant recipients and is often a cause of late mortality. It can affect any tissue, and involvement of the lungs—target organs of particular importance—can lead to chronic respiratory failure due to bronchiolitis obliterans.</p><p class="elsevierStyleSimplePara elsevierViewall">We report the case of a lung transplant in a woman who developed bronchiolitis obliterans after receiving a marrow transplant to treat bone marrow aplasia. Three years later, clinical course was satisfactory, with full functional recovery.</p>" ] "es" => array:1 [ "resumen" => "<p class="elsevierStyleSimplePara elsevierViewall">La enfermedad del injerto contra el huésped es una com-plicación importante de los pacientes sometidos a trasplante de médula ósea, en quienes es causa de una elevada mortali-dad tardía. Puede afectar a cualquier tejido y, cuando afecta a los pulmones, que son órganos diana de particular rele-vancia, acarrea insuficiencia respiratoria crónica secunda-ria al desarrollo de bronquiolitis obliterante.</p><p class="elsevierStyleSimplePara elsevierViewall">Presentamos el caso de una paciente con trasplante pulmonar por bronquiolitis obliterante tras haber recibido un trasplante de médula ósea por aplasia medular. La evolución tras el trasplante pulmonar, a los 3 años de seguimiento, es favorable, con recuperación clínica y funcional completa.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "REFERENCES" "seccion" => array:1 [ 0 => array:1 [ "bibliografiaReferencia" => array:11 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Bone marrow transplantation" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "JO Armitage" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1056/NEJM199403243301206" "Revista" => array:6 [ "tituloSerie" => "N Engl J Med" "fecha" => "1994" "volumen" => "330" "paginaInicial" => "827" "paginaFinal" => "838" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8114836" "web" => "Medline" ] ] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib2" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "A chronic pulmonary syndrome associated with graft-versus-host disease after allogenic marrow transplantation" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "AP Schwarer" 1 => "JMB Hughes" 2 => "B Trotman-Dieckenson" 3 => "T Krausz" 4 => "JM Goldman" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Transplantation" "fecha" => "1992" "volumen" => "54" "paginaInicial" => "1002" "paginaFinal" => "1008" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1465767" "web" => "Medline" ] ] ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib3" "etiqueta" => "3" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Bronchiolitis associated with bone marrow transplantation" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "SW Crawford" 1 => "JG Clark" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Clin Chest Med" "fecha" => "1993" "volumen" => "14" "paginaInicial" => "741" "paginaFinal" => "749" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8313677" "web" => "Medline" ] ] ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib4" "etiqueta" => "4" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Trasplante pulmonar. 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=> array:3 [ "identificador" => "bib7" "etiqueta" => "7" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Lung transplantation in a patient with a prior bone marrow transplant" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "JH Calhoon" 1 => "S Levine" 2 => "A Anzueto" 3 => "CL Bryan" 4 => "JK Trinkle" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Chest" "fecha" => "1992" "volumen" => "102" "paginaInicial" => "948" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1516429" "web" => "Medline" ] ] ] ] ] ] ] ] 7 => array:3 [ "identificador" => "bib8" "etiqueta" => "8" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Transplantation of a lobe of lung from mother to child following previous transplantation with maternal bone marrow" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "UG Svendson" 1 => "S Aggestrup" 2 => "C Heilmann" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Heart Lung Transplant" "fecha" => "1999" "volumen" => "18" "paginaInicial" => "388" "paginaFinal" => "390" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10226907" "web" => "Medline" ] ] ] ] ] ] ] ] 8 => array:3 [ "identificador" => "bib9" "etiqueta" => "9" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Successful lung transplantation for bronchiolitis obliterans after allogenic marrow transplantation" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "W Rabitsch" 1 => "E Deviatko" 2 => "F Keil" 3 => "C Herold" 4 => "G Dekan" 5 => "HT Greinix" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Transplantation" "fecha" => "2001" "volumen" => "71" "paginaInicial" => "1341" 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=> array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Immunologic, morphologic, and functional evaluation of long-term-surviving beagle lung allograft recipients treated with lethal total-body irradiation, autologous bone marrow, and methotrexate" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "AJ Norin" 1 => "EM Goodell" 2 => "SL Kamholz" 3 => "FJ Veith" 4 => "DA Blumenstock" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Transplantation" "fecha" => "1987" "volumen" => "44" "paginaInicial" => "179" "paginaFinal" => "184" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3307041" "web" => "Medline" ] ] ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/15792129/0000004200000003/v1_201305150239/S1579212906601365/v1_201305150239/en/main.assets" "Apartado" => null "PDF" => 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