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Evolution Over Time in Over Perceivers of Dyspnea in Asthma
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"apellidos" => "Manresa" ] ] ] ] ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1579212906601286?idApp=UINPBA00003Z" "url" => "/15792129/0000004200000003/v1_201305150239/S1579212906601286/v1_201305150239/en/main.assets" ] "en" => array:15 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Original Articles</span>" "titulo" => "Evolution Over Time in Over Perceivers of Dyspnea in Asthma" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "120" "paginaFinal" => "124" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "E. Martínez-Moragón, M. Perpiñá, A. Belloch, B. Serra, A. Lloris, V. Macián" "autores" => array:6 [ 0 => array:5 [ "preGrado" => "Dra." "nombre" => "E." "apellidos" => "Martínez-Moragón" "email" => array:1 [ 0 => "emm01v@saludalia.com" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor1" ] ] ] 1 => array:3 [ "nombre" => "M." "apellidos" => "Perpiñá" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff2" ] ] ] 2 => array:3 [ "nombre" => "A." "apellidos" => "Belloch" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">c</span>" "identificador" => "aff3" ] ] ] 3 => array:3 [ "nombre" => "B." "apellidos" => "Serra" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] ] ] 4 => array:3 [ "nombre" => "A." "apellidos" => "Lloris" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff2" ] ] ] 5 => array:3 [ "nombre" => "V." "apellidos" => "Macián" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff2" ] ] ] ] "afiliaciones" => array:3 [ 0 => array:3 [ "entidad" => "Servicio de Neumología, Hospital de Sagunto, Sagunto, Valencia, Spain" "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] 1 => array:3 [ "entidad" => "Servicio de Neumología, Hospital Universitario La Fe, Valencia, Spain" "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff2" ] 2 => array:3 [ "entidad" => "Departamento de Personalidad, Evaluación y Tratamientos Psicológicos, Facultad de Psicología, Universidad de Valencia, Valencia, Spain" "etiqueta" => "<span class="elsevierStyleSup">c</span>" "identificador" => "aff3" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor1" "etiqueta" => "*" "correspondencia" => "Correspondence: Dra. E. Martínez-Moragón. Avda. Pérez Galdós, 12-10. 46007 Valencia. España" ] ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2005-04-22" "fechaAceptado" => "2005-09-13" "PalabrasClave" => array:2 [ "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key words" "identificador" => "xpalclavsec154262" "palabras" => array:5 [ 0 => "Dyspnea" 1 => "Asthma" 2 => "Perception" 3 => "Over perception" 4 => "Hyperventilation" ] ] ] "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec154263" "palabras" => array:5 [ 0 => "Disnea" 1 => "Asma" 2 => "Percepción" 3 => "Hiperpercepción" 4 => "Hiperventilación" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "en" => array:1 [ "resumen" => "<span class="elsevierStyleSectionTitle">Objective</span><p class="elsevierStyleSimplePara elsevierViewall">In previous studies we identified a subgroup of patients whose perception of breathlessness was exaggerated during acute bronchoconstriction and who were termed “over perceivers” or “hyperperceivers.” In this study we aimed to determine whether such over perception is sporadic or stable over time. We also examined whether there is an association between over perception of dyspnea and hyperventilation syndrome.</p> <span class="elsevierStyleSectionTitle">Patients and methods</span><p class="elsevierStyleSimplePara elsevierViewall">The subjects were 22 stable asthmatics (11 men, 11 women) who had been over perceivers of dyspnea in a study 9 years earlier. After a medical history was taken, a patient performed forced spirometry and a severity classification was made according to the criteria of the Global Initiative for Asthma (GINA). A bronchial histamine challenge was then administered to measure dose-related perception of dyspnea on a Borg scale, according to a procedure that was similar to the one used 9 years earlier by the same investigator. The patients were also asked for a subjective assessment of the severity of their asthma (scale, 0–10) and to respond to items on the Nijmegen hyperventilation questionnaire and the trait form of the State-Trait Anxiety Inventory.</p> <span class="elsevierStyleSectionTitle">Results</span><p class="elsevierStyleSimplePara elsevierViewall">The overall perception of severity of disease, level of anxiety, and perception of dyspnea at rest were lower after 9 years (<span class="elsevierStyleItalic">P</span> <.001). No change was observed in bronchial hyperresponsiveness (dose of inhaled histamine required to provoke a 20% decline in forced expiratory volume in the first second [FEV<span class="elsevierStyleInf">1</span>]-PD<span class="elsevierStyleInf">20</span>) or objective parameters of severity (FEV<span class="elsevierStyleInf">1</span> and GINA classification). Fourteen asthmatics (64%) were still over perceivers and the other patients had changed: 6 were normal perceivers and 2 were “poor perceivers.” Only subjective perception of disease severity improved for the patients who were still over perceivers; the other patients, on the other hand, showed improvements in subjective assessments, objective ones (except PD<span class="elsevierStyleInf">20</span>), and anxiety. Finally, those who remained over perceivers had higher scores for anxiety (24 vs 15; <span class="elsevierStyleItalic">P</span> <.05) and hyperventilation (18 vs 13; <span class="elsevierStyleItalic">P</span>= not significant).</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p class="elsevierStyleSimplePara elsevierViewall">Most over perceivers of dyspnea remain so over the years and this trait is related to anxiety. We have been unable to demonstrate an association with hyperventilation syndrome.</p>" ] "es" => array:1 [ "resumen" => "<span class="elsevierStyleSectionTitle">Objetivo</span><p class="elsevierStyleSimplePara elsevierViewall">En investigaciones previas para estudiar la percepción de disnea de los asmáticos durante la bronco-constricción aguda, encontramos un subgrupo de pacientes que presentaban una percepción exagerada (hiperpercepto-res). En el presente trabajo hemos querido comprobar si esta alteración perceptiva es un fenómeno esporádico o mantenido en el tiempo. Asimismo nos planteamos conocer si existe una asociación entre la hiperpercepción de la disnea y el síndrome de hiperventilación.</p> <span class="elsevierStyleSectionTitle">Pacientes y métodos</span><p class="elsevierStyleSimplePara elsevierViewall">Se incluyó en el estudio a 22 asmáticos estables que en un estudio realizado 9 años antes se habían mostrado hiperperceptores de disnea (11 varones y 11 mujeres). Tras una espirometría forzada y una entrevista clínica, se les clasificó en su categoría de gravedad de asma -GINA (Global Initiative for Asthma)-. A continuación se les sometió a una prueba de provocación bronquial con histamina para medir la disnea percibida con cada dosis en una escala de Borg (procedimiento similar al empleado 9 años antes por el mismo investigador). Además se les pidió una valoración subjetiva de la gravedad de su asma (escala de 0–10) y que relle-naran el cuestionario Nijmegen de hiperventilación y el STAI-R (State-Trait Anxiety Inventory) de ansiedad.</p> <span class="elsevierStyleSectionTitle">Resultados</span><p class="elsevierStyleSimplePara elsevierViewall">Globalmente, transcurridos 9 años, se han reducido (p < 0,001) la percepción de gravedad del asma, la ansiedad y la disnea basal. No se observaron cambios en el grado de hiperrespuesta bronquial (PD<span class="elsevierStyleInf">20</span>: concentración de histamina capaz de provocar un descenso del volumen espi-ratorio forzado en el primer segundo del 20%) ni en pará-metros objetivos de gravedad (volumen espiratorio forzado en el primer segundo y GINA). Catorce asmáticos seguían siendo hiperperceptores (64%) y en el resto había cambia-do la percepción de la disnea: 6 normoperceptores y 2 hipo-perceptores. En el grupo que seguía siendo hiperperceptor sólo mejoró significativamente la percepción subjetiva de gravedad; en cambio, en el grupo restante mejoraron la en-fermedad subjetiva y objetivamente (excepto la PD<span class="elsevierStyleInf">20</span>) y la ansiedad. Por último, los que continuaban siendo hiperperceptores puntuaron más alto en los cuestionarios de ansiedad (24 frente a 15; p < 0,05) e hiperventilación (18 fren-te a 13; p = no significativa).</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p class="elsevierStyleSimplePara elsevierViewall">La mayoría de hiperperceptores de disnea se mantienen así con el paso de los años, lo cual está relacio-nado con la ansiedad (no hemos podido demostrar su asociación con el síndrome de hiperventilación).</p>" ] ] "NotaPie" => array:1 [ 0 => array:1 [ "nota" => "<p class="elsevierStyleNotepara">This study was partially funded by grant RTIC-03/11 from the Red RESPIRA-Instituto de Salud Carlos III.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "REFERENCES" "seccion" => array:1 [ 0 => array:1 [ "bibliografiaReferencia" => array:19 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" 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| Year/Month | Html | Total | |
|---|---|---|---|
| 2024 November | 3 | 1 | 4 |
| 2024 October | 26 | 22 | 48 |
| 2024 September | 30 | 11 | 41 |
| 2024 August | 44 | 31 | 75 |
| 2024 July | 21 | 19 | 40 |
| 2024 June | 33 | 18 | 51 |
| 2024 May | 34 | 28 | 62 |
| 2024 April | 11 | 21 | 32 |
| 2024 March | 17 | 23 | 40 |
| 2024 February | 15 | 15 | 30 |
| 2023 March | 2 | 0 | 2 |
| 2023 February | 20 | 20 | 40 |
| 2023 January | 15 | 28 | 43 |
| 2022 December | 26 | 25 | 51 |
| 2022 November | 20 | 22 | 42 |
| 2022 October | 19 | 34 | 53 |
| 2022 September | 12 | 23 | 35 |
| 2022 August | 18 | 27 | 45 |
| 2022 July | 18 | 42 | 60 |
| 2022 June | 18 | 27 | 45 |
| 2022 May | 15 | 40 | 55 |
| 2022 April | 15 | 24 | 39 |
| 2022 March | 21 | 30 | 51 |
| 2022 February | 18 | 32 | 50 |
| 2022 January | 16 | 41 | 57 |
| 2021 December | 13 | 46 | 59 |
| 2021 November | 21 | 43 | 64 |
| 2021 October | 23 | 60 | 83 |
| 2021 September | 13 | 48 | 61 |
| 2021 August | 10 | 29 | 39 |
| 2021 July | 8 | 22 | 30 |
| 2021 June | 16 | 27 | 43 |
| 2021 May | 29 | 43 | 72 |
| 2021 April | 66 | 46 | 112 |
| 2021 March | 26 | 18 | 44 |
| 2021 February | 11 | 13 | 24 |
| 2021 January | 4 | 6 | 10 |
| 2020 December | 2 | 10 | 12 |
| 2020 November | 8 | 6 | 14 |
| 2020 October | 6 | 9 | 15 |
| 2020 September | 4 | 7 | 11 |
| 2020 August | 8 | 8 | 16 |
| 2020 July | 11 | 12 | 23 |
| 2020 June | 4 | 6 | 10 |
| 2020 May | 12 | 12 | 24 |
| 2020 April | 11 | 9 | 20 |
| 2020 March | 6 | 12 | 18 |
| 2020 February | 9 | 15 | 24 |
| 2020 January | 7 | 17 | 24 |
| 2019 December | 14 | 17 | 31 |
| 2019 November | 7 | 8 | 15 |
| 2019 October | 4 | 5 | 9 |
| 2019 September | 7 | 14 | 21 |
| 2019 August | 6 | 6 | 12 |
| 2019 July | 6 | 16 | 22 |
| 2019 June | 8 | 16 | 24 |
| 2019 May | 12 | 14 | 26 |
| 2019 April | 24 | 17 | 41 |
| 2019 March | 13 | 17 | 30 |
| 2019 February | 5 | 7 | 12 |
| 2019 January | 2 | 9 | 11 |
| 2018 December | 9 | 13 | 22 |
| 2018 November | 5 | 12 | 17 |
| 2018 October | 22 | 17 | 39 |
| 2018 September | 11 | 13 | 24 |
| 2018 May | 4 | 0 | 4 |
| 2018 April | 4 | 6 | 10 |
| 2018 March | 5 | 5 | 10 |
| 2018 February | 7 | 8 | 15 |
| 2018 January | 7 | 11 | 18 |
| 2017 December | 8 | 8 | 16 |
| 2017 November | 4 | 4 | 8 |
| 2017 October | 4 | 9 | 13 |
| 2017 September | 7 | 4 | 11 |
| 2017 August | 7 | 14 | 21 |
| 2017 July | 3 | 7 | 10 |
| 2017 June | 6 | 15 | 21 |
| 2017 May | 8 | 18 | 26 |
| 2017 April | 0 | 4 | 4 |
| 2017 March | 3 | 8 | 11 |
| 2017 February | 0 | 3 | 3 |
| 2017 January | 2 | 1 | 3 |
| 2016 December | 13 | 7 | 20 |
| 2016 November | 18 | 6 | 24 |
| 2016 October | 15 | 8 | 23 |
| 2016 September | 5 | 3 | 8 |
| 2016 August | 8 | 4 | 12 |
| 2016 July | 6 | 2 | 8 |
| 2016 March | 2 | 0 | 2 |
| 2015 December | 2 | 0 | 2 |
| 2015 October | 75 | 7 | 82 |
| 2015 September | 56 | 9 | 65 |
| 2015 August | 48 | 10 | 58 |
| 2015 July | 61 | 4 | 65 |
| 2015 June | 50 | 11 | 61 |
| 2015 May | 69 | 9 | 78 |
| 2015 April | 46 | 8 | 54 |
| 2015 March | 55 | 15 | 70 |
| 2015 February | 43 | 7 | 50 |
| 2015 January | 35 | 11 | 46 |
| 2014 December | 45 | 5 | 50 |
| 2014 November | 54 | 5 | 59 |
| 2014 October | 68 | 10 | 78 |
| 2014 September | 64 | 8 | 72 |
| 2014 August | 71 | 12 | 83 |
| 2014 July | 54 | 10 | 64 |
| 2014 June | 90 | 10 | 100 |
| 2014 May | 95 | 14 | 109 |
| 2014 April | 97 | 17 | 114 |
| 2014 March | 103 | 14 | 117 |
| 2014 February | 100 | 21 | 121 |
| 2014 January | 83 | 14 | 97 |
| 2013 December | 96 | 18 | 114 |
| 2013 November | 78 | 12 | 90 |
| 2013 October | 76 | 14 | 90 |
| 2013 September | 476 | 14 | 490 |
| 2013 August | 679 | 14 | 693 |
| 2013 July | 393 | 11 | 404 |
| 2013 June | 65 | 6 | 71 |
| 2013 May | 39 | 3 | 42 |
| 2013 April | 36 | 5 | 41 |
| 2013 March | 6 | 2 | 8 |
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