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Original Article
Synergic Integration of the miRNome, Machine Learning and Bioinformatics for the Identification of Potential Disease-Modifying Agents in Obstructive Sleep Apnea
Thalia Belmontea,b, Iván D. Beniteza,b,c, María C. García-Hidalgoa,b, Marta Molineroa,b, Lucía Pinillab,d, Olga Míngueza, Rafaela Vacaa, Maria Aguilàa, Anna Moncusí-Moixa, Gerard Torresb,d, Olga Medianoe, Juan F. Masaf, Maria J. Masdeug, Blanca Montero-San-Martính, Mercè Ibarzh, Pablo Martinez-Camblori,j, Alberto Gómez-Carballab,k,l, Antonio Salasb,k,l, Federico Martinón-Torresb,k,m, Ferran Barbéa,b..., Manuel Sánchez-de-la-Torreb,d,n,o,1,
, David de Gonzalo-Calvoa,b,1,
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Corresponding author
Corresponding author
a Translational Research in Respiratory Medicine, University Hospital Arnau de Vilanova and Santa Maria, IRBLleida, Lleida, Spain
b CIBER of Respiratory Diseases (CIBERES), Institute of Health Carlos III, Madrid, Spain
c Department of Basic Medical Sciences, University of Lleida, Lleida, Spain
d Precision Medicine in Chronic Diseases, University Hospital Arnau de Vilanova and Santa Maria, IRB Lleida, Department of Nursing and Physiotherapy, Faculty of Nursing and Physiotherapy, University of Lleida, Lleida, Spain
e Pneumology Department, University Hospital of Guadalajara, Guadalajara, Spain
f San Pedro de Alcantara Hospital, Instituto Universitario de Investigación Biosanitaria de Extremadura, Cáceres, Spain
g Respiratory and Sleep Department, Parc Taulí University Hospital, Parc Taulí Research and Innovation Institute, Autonomous University of Barcelona, Sabadell, Spain
h Department of Clinical Laboratory, University Hospital Arnau de Vilanova, IRBLleida, Lleida, Spain
i Anesthesiology Department, Geisel School of Medicine at Dartmouth, Hanover, NH, USA
j Faculty of Health Sciences, Universidad Autonoma de Chile, Providencia, Chile
k Genetics, Vaccines and Infections Research Group (GenViP), Instituto de Investigación Sanitaria de Santiago, Universidade de Santiago de Compostela (USC), 15706 Santiago de Compostela, Galicia, Spain
l Unidade de Xenética, Instituto de Ciencias Forenses, Facultade de Medicina, Universidade de Santiago de Compostela (USC) and Genetica de Poblaciones en Biomedicina (GenPoB) Research Group, Instituto de Investigación Sanitaria (IDIS), Hospital Clínico Universitario de Santiago (SERGAS), Santiago de Compostela, Galicia, Spain
m Translational Pediatrics and Infectious Diseases, Department of Pediatrics, Hospital Clínico Universitario de Santiago de Compostela, Santiago de Compostela, Galicia, Spain
n Group of Precision Medicine in Chronic Diseases, Hospital Nacional de Parapléjicos, IDISCAM, Spain
o Department of Nursing, Physiotherapy and Occupational Therapy, Faculty of Physiotherapy and Nursing, University of Castilla-La Mancha, Toledo, Spain
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