array:23 [
  "pii" => "S0300289622004409"
  "issn" => "03002896"
  "doi" => "10.1016/j.arbres.2022.05.009"
  "estado" => "S300"
  "fechaPublicacion" => "2022-10-01"
  "aid" => "3127"
  "copyright" => "SEPAR"
  "copyrightAnyo" => "2022"
  "documento" => "simple-article"
  "crossmark" => 1
  "subdocumento" => "cor"
  "cita" => "Arch Bronconeumol. 2022;58:729-30"
  "abierto" => array:3 [
    "ES" => true
    "ES2" => true
    "LATM" => true
  ]
  "gratuito" => true
  "lecturas" => array:1 [
    "total" => 0
  ]
  "itemSiguiente" => array:18 [
    "pii" => "S0300289622004446"
    "issn" => "03002896"
    "doi" => "10.1016/j.arbres.2022.05.012"
    "estado" => "S300"
    "fechaPublicacion" => "2022-10-01"
    "aid" => "3132"
    "copyright" => "SEPAR"
    "documento" => "simple-article"
    "crossmark" => 1
    "subdocumento" => "cor"
    "cita" => "Arch Bronconeumol. 2022;58:731-2"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:1 [
      "total" => 0
    ]
    "en" => array:9 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Letter to the Director</span>"
      "titulo" => "Alpha-1 Antitrypsin Deficiency Severe and No Severe&#46; Is It Benefit or Risk&#63;"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "731"
          "paginaFinal" => "732"
        ]
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Jos&#233; Mar&#237;a Hern&#225;ndez P&#233;rez, Claudia Vivian L&#243;pez Charry"
          "autores" => array:2 [
            0 => array:2 [
              "nombre" => "Jos&#233; Mar&#237;a"
              "apellidos" => "Hern&#225;ndez P&#233;rez"
            ]
            1 => array:2 [
              "nombre" => "Claudia Vivian"
              "apellidos" => "L&#243;pez Charry"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289622004446?idApp=UINPBA00003Z"
    "url" => "/03002896/0000005800000010/v2_202302271800/S0300289622004446/v2_202302271800/en/main.assets"
  ]
  "itemAnterior" => array:18 [
    "pii" => "S0300289622003398"
    "issn" => "03002896"
    "doi" => "10.1016/j.arbres.2022.05.004"
    "estado" => "S300"
    "fechaPublicacion" => "2022-10-01"
    "aid" => "3115"
    "copyright" => "SEPAR"
    "documento" => "simple-article"
    "crossmark" => 1
    "subdocumento" => "cor"
    "cita" => "Arch Bronconeumol. 2022;58:727-8"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:1 [
      "total" => 0
    ]
    "en" => array:10 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Letter to the Director</span>"
      "titulo" => "Why Use Aprepitant Only as a Cough Suppressant in Lung Cancer When at Higher Doses it Could Also Exert an Antitumor Action&#63;"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "727"
          "paginaFinal" => "728"
        ]
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:7 [
          "identificador" => "fig0005"
          "etiqueta" => "Fig&#46; 1"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "gr1.jpeg"
              "Alto" => 1621
              "Ancho" => 2508
              "Tamanyo" => 282999
            ]
          ]
          "descripcion" => array:1 [
            "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Lung cancer &#40;LC&#41; patients&#58; substance P &#40;SP&#41;&#44; via the neurokinin-1 receptor &#40;NK-1R&#41;&#44; promotes cough and tumor progression&#46; The NK-1R antagonist aprepitant could exert a dual therapeutic effect in these patients&#58; cough suppressant and antitumor action&#46;</p>"
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Miguel Mu&#241;oz, Miguel E&#46; Mu&#241;oz, Ferran Morell, Rafael Cove&#241;as"
          "autores" => array:4 [
            0 => array:2 [
              "nombre" => "Miguel"
              "apellidos" => "Mu&#241;oz"
            ]
            1 => array:2 [
              "nombre" => "Miguel E&#46;"
              "apellidos" => "Mu&#241;oz"
            ]
            2 => array:2 [
              "nombre" => "Ferran"
              "apellidos" => "Morell"
            ]
            3 => array:2 [
              "nombre" => "Rafael"
              "apellidos" => "Cove&#241;as"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289622003398?idApp=UINPBA00003Z"
    "url" => "/03002896/0000005800000010/v2_202302271800/S0300289622003398/v2_202302271800/en/main.assets"
  ]
  "en" => array:12 [
    "idiomaDefecto" => true
    "cabecera" => "<span class="elsevierStyleTextfn">Letter to the Editor</span>"
    "titulo" => "Medium- and Long-Term Consequences of SARS-CoV-2 Infection on COPD Patients"
    "tieneTextoCompleto" => true
    "saludo" => "To the Director&#44;"
    "paginas" => array:1 [
      0 => array:2 [
        "paginaInicial" => "729"
        "paginaFinal" => "730"
      ]
    ]
    "autores" => array:1 [
      0 => array:4 [
        "autoresLista" => "Juan Marco Figueira-Gon&#231;alves, Rafael Golpe"
        "autores" => array:2 [
          0 => array:4 [
            "nombre" => "Juan Marco"
            "apellidos" => "Figueira-Gon&#231;alves"
            "email" => array:1 [
              0 => "juanmarcofigueira@gmail.com"
            ]
            "referencia" => array:3 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff0005"
              ]
              1 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">b</span>"
                "identificador" => "aff0010"
              ]
              2 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">&#42;</span>"
                "identificador" => "cor0005"
              ]
            ]
          ]
          1 => array:3 [
            "nombre" => "Rafael"
            "apellidos" => "Golpe"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">c</span>"
                "identificador" => "aff0015"
              ]
            ]
          ]
        ]
        "afiliaciones" => array:3 [
          0 => array:3 [
            "entidad" => "Pneumology and Thoracic Surgery Service&#44; University Hospital Nuestra Se&#241;ora de Candelaria&#44; Santa Cruz de Tenerife&#44; Spain"
            "etiqueta" => "a"
            "identificador" => "aff0005"
          ]
          1 => array:3 [
            "entidad" => "University Institute of Tropical Disease and Public Health of the Canary Islands&#44; University of La Laguna&#44; Santa Cruz de Tenerife&#44; Spain"
            "etiqueta" => "b"
            "identificador" => "aff0010"
          ]
          2 => array:3 [
            "entidad" => "Pneumology Service&#44; University Hospital Lucus Augusti&#44; Lugo&#44; Spain"
            "etiqueta" => "c"
            "identificador" => "aff0015"
          ]
        ]
        "correspondencia" => array:1 [
          0 => array:3 [
            "identificador" => "cor0005"
            "etiqueta" => "&#8270;"
            "correspondencia" => "Corresponding author&#46;"
          ]
        ]
      ]
    ]
    "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">We have read with interest the article by Chiner-Vives et al&#46;<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">1</span></a> on the impact of coronavirus disease-2019 &#40;COVID-19&#41; on previous respiratory diseases&#46; As the authors mention&#44; current evidence indicates that chronic obstructive pulmonary disease &#40;COPD&#41; patients are at increased risk of suffering an infection by severe acute respiratory syndrome coronavirus-2 &#40;SARS-CoV-2&#41; and are more likely to undergo a serious form of the infection requiring hospitalization&#46; However&#44; there is uncertainty about the medium- and long-term consequences of SARS-CoV-2 infection in this population&#46; There are reasons to speculate that COPD patients might be particularly susceptible to late sequelae from COVID-19&#46; About 30&#37; of patients with COVID-19 may suffer from post-COVID syndrome&#44; or &#8220;long COVID&#8221; and this percentage may reach 50&#37; of patients who suffered a serious illness that required hospital admission&#46;<a class="elsevierStyleCrossRef" href="#bib0035"><span class="elsevierStyleSup">2</span></a> Therefore&#44; it is plausible that COPD patients could not only suffer from a more severe acute form of the disease&#44; but are also at risk of persistent symptoms&#46; Long COVID manifestations include dyspnea&#44; lower limbs weakness&#44; arthromyalgia and fatigue&#44;<a class="elsevierStyleCrossRef" href="#bib0035"><span class="elsevierStyleSup">2</span></a> and COPD itself is related to these symptoms&#46; The coexistence of both diseases could possibly multiply their effects and impact on dimensions of illness with a demonstrated influence on quality of life and survival&#44; such as physical activity&#46; In fact&#44; COPD patients reduced their activity during COVID lockdowns&#44; with the consequence of a decreased ability to perform daily activities and aggravation of mood disorders&#46;<a class="elsevierStyleCrossRef" href="#bib0040"><span class="elsevierStyleSup">3</span></a> Long COVID could only worsen these outcomes&#46; Regarding mood disorders&#44; depression can appear in up to 25&#37; of subjects 9 months after COVID-19&#46;<a class="elsevierStyleCrossRef" href="#bib0035"><span class="elsevierStyleSup">2</span></a> It is credible that pre-existing depression can worsen after SARS-CoV-2 infection&#44; and this is a common comorbidity in COPD that influences its natural history in aspects as important as the incidence of exacerbations&#46;<a class="elsevierStyleCrossRef" href="#bib0045"><span class="elsevierStyleSup">4</span></a> Furthermore&#44; COPD exacerbations are linked to an increased risk of delayed cardiovascular events&#46; A recent study found that&#44; among patients who reported symptoms of acute respiratoy illness and who were tested for SARS-CoV-2 infection&#44; frequent and prolonged alterations in resting heart rate were found in individuals with COVID-19&#44; compared to COVID-19 negative subjects&#46;<a class="elsevierStyleCrossRef" href="#bib0050"><span class="elsevierStyleSup">5</span></a> This raises concern that COPD exacerbations caused by SARS-CoV-2 infection may further increase the risk of cardiovascular adverse effects&#46;</p><p id="par0010" class="elsevierStylePara elsevierViewall">It should be noted that COVID-19 vaccination has radically changed the natural history of the disease and&#44; therefore&#44; the current evidence mentioned in the previous paragraph must be interpreted with caution in the new global situation of the pandemic&#46; However&#44; reinfections with emerging variants of SARS-CoV-2 are common among vaccinated individuals and will be a concern for COPD patients in the foreseeable future&#46; Although COVID-19 is less severe in vaccinated people&#44; it remains to be clarified whether vaccination will reduce the risk of SARS-Cov-2 infection in COPD to the same extent as in people without COPD&#46; Furthermore&#44; we do not know yet the potential impact of COVID-19 on the effectiveness of current therapies used to prevent COPD exacerbations&#46; Until more evidence is available&#44; clinicians should carefully monitor COPD patients after COVID-19&#44; taking into account the risk of both respiratory and multisystem adverse effects&#46;</p><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Authors&#8217; contribution</span><p id="par0015" class="elsevierStylePara elsevierViewall">All authors have made substantial contributions to the intellectual content and manuscript design and drafting&#46;</p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Ethical approval</span><p id="par0020" class="elsevierStylePara elsevierViewall">All authors gave their approval to the final version of the manuscript and declare to have met the requirements for authorship&#46;</p></span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0015">Funding</span><p id="par0025" class="elsevierStylePara elsevierViewall">No financial support has been received for conducting the study or drafting the manuscript&#46;</p></span><span id="sec0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0020">Conflict of interest</span><p id="par0030" class="elsevierStylePara elsevierViewall">The authors declare not to have any direct or indirect conflict of interest related to the manuscript contents&#46;</p></span></span>"
    "textoCompletoSecciones" => array:1 [
      "secciones" => array:5 [
        0 => array:2 [
          "identificador" => "sec0005"
          "titulo" => "Authors&#8217; contribution"
        ]
        1 => array:2 [
          "identificador" => "sec0010"
          "titulo" => "Ethical approval"
        ]
        2 => array:2 [
          "identificador" => "sec0015"
          "titulo" => "Funding"
        ]
        3 => array:2 [
          "identificador" => "sec0020"
          "titulo" => "Conflict of interest"
        ]
        4 => array:1 [
          "titulo" => "References"
        ]
      ]
    ]
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "bibliografia" => array:2 [
      "titulo" => "References"
      "seccion" => array:1 [
        0 => array:2 [
          "identificador" => "bibs0015"
          "bibliografiaReferencia" => array:5 [
            0 => array:3 [
              "identificador" => "bib0030"
              "etiqueta" => "1"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Short and long-term impact of COVID-19 infection on previous respiratory diseases"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "E&#46; Chiner-Vives"
                            1 => "R&#46; Cordovilla-P&#233;rez"
                            2 => "D&#46; de la Rosa-Carrillo"
                            3 => "M&#46; Garc&#237;a-Clemente"
                            4 => "J&#46;L&#46; Izquierdo-Alonso"
                            5 => "R&#46; Otero-Candelera"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:2 [
                        "tituloSerie" => "Arch Bronconeumol"
                        "fecha" => "2022"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib0035"
              "etiqueta" => "2"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Global prevalence of post COVID-19 condition or long COVID&#58; a meta-analysis and systematic review"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "C&#46; Chen"
                            1 => "S&#46;R&#46; Haupert"
                            2 => "L&#46; Zimmermann"
                            3 => "X&#46; Shi"
                            4 => "L&#46;G&#46; Fritsche"
                            5 => "B&#46; Mukherjee"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:3 [
                        "tituloSerie" => "J Infect Dis"
                        "fecha" => "2022"
                        "paginaInicial" => "jiac136"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib0040"
              "etiqueta" => "3"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "COPD in the time of COVID-19&#58; an analysis of acute exacerbations and reported behavioural changes in patients with COPD"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "H&#46; McAuley"
                            1 => "K&#46; Hadley"
                            2 => "O&#46; Elneima"
                            3 => "C&#46;E&#46; Brightling"
                            4 => "R&#46;A&#46; Evans"
                            5 => "M&#46;C&#46; Steiner"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1183/23120541.00718-2020"
                      "Revista" => array:6 [
                        "tituloSerie" => "ERJ Open Res"
                        "fecha" => "2021"
                        "volumen" => "7"
                        "paginaInicial" => "00718"
                        "paginaFinal" => "2020"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/33527075"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib0045"
              "etiqueta" => "4"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Impact of anxiety and depression on the prognosis of copd exacerbations"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "M&#46;G&#46; Sandra"
                            1 => "G&#46;S&#46; Mar&#237;a-Teresa"
                            2 => "C&#46; Jos&#233;-Mart&#237;n"
                            3 => "S&#46; Francisco-Javier"
                            4 => "C&#46;&#193;&#46; Ux&#237;o"
                            5 => "D&#46;O&#46; Liliana"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1186/s12890-022-01934-y"
                      "Revista" => array:5 [
                        "tituloSerie" => "BMC Pulm Med"
                        "fecha" => "2022"
                        "volumen" => "22"
                        "paginaInicial" => "169"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/35488330"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bib0050"
              "etiqueta" => "5"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Assessment of prolonged physiological and behavioral changes associated with COVID-19 infection"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "J&#46;M&#46; Radin"
                            1 => "G&#46; Quer"
                            2 => "E&#46; Ramos"
                            3 => "K&#46; Baca-Motes"
                            4 => "M&#46; Gadaleta"
                            5 => "E&#46;J&#46; Topol"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1001/jamanetworkopen.2021.15959"
                      "Revista" => array:5 [
                        "tituloSerie" => "JAMA Netw Open"
                        "fecha" => "2021"
                        "volumen" => "4"
                        "paginaInicial" => "e2115959"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/34232306"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "en"
  "url" => "/03002896/0000005800000010/v2_202302271800/S0300289622004409/v2_202302271800/en/main.assets"
  "Apartado" => array:4 [
    "identificador" => "94562"
    "tipo" => "SECCION"
    "es" => array:2 [
      "titulo" => "Letters to the Director"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "es"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/03002896/0000005800000010/v2_202302271800/S0300289622004409/v2_202302271800/en/main.pdf?idApp=UINPBA00003Z&text.app=https://archbronconeumol.org/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289622004409?idApp=UINPBA00003Z"
]
Share
Journal Information

Statistics

Follow this link to access the full text of the article

Letter to the Editor
Medium- and Long-Term Consequences of SARS-CoV-2 Infection on COPD Patients
Juan Marco Figueira-Gonçalvesa,b,
Corresponding author
juanmarcofigueira@gmail.com

Corresponding author.
, Rafael Golpec
a Pneumology and Thoracic Surgery Service, University Hospital Nuestra Señora de Candelaria, Santa Cruz de Tenerife, Spain
b University Institute of Tropical Disease and Public Health of the Canary Islands, University of La Laguna, Santa Cruz de Tenerife, Spain
c Pneumology Service, University Hospital Lucus Augusti, Lugo, Spain
Read
15970
Times
was read the article
1332
Total PDF
14638
Total HTML
Share statistics
 array:23 [
  "pii" => "S0300289622004409"
  "issn" => "03002896"
  "doi" => "10.1016/j.arbres.2022.05.009"
  "estado" => "S300"
  "fechaPublicacion" => "2022-10-01"
  "aid" => "3127"
  "copyright" => "SEPAR"
  "copyrightAnyo" => "2022"
  "documento" => "simple-article"
  "crossmark" => 1
  "subdocumento" => "cor"
  "cita" => "Arch Bronconeumol. 2022;58:729-30"
  "abierto" => array:3 [
    "ES" => true
    "ES2" => true
    "LATM" => true
  ]
  "gratuito" => true
  "lecturas" => array:1 [
    "total" => 0
  ]
  "itemSiguiente" => array:18 [
    "pii" => "S0300289622004446"
    "issn" => "03002896"
    "doi" => "10.1016/j.arbres.2022.05.012"
    "estado" => "S300"
    "fechaPublicacion" => "2022-10-01"
    "aid" => "3132"
    "copyright" => "SEPAR"
    "documento" => "simple-article"
    "crossmark" => 1
    "subdocumento" => "cor"
    "cita" => "Arch Bronconeumol. 2022;58:731-2"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:1 [
      "total" => 0
    ]
    "en" => array:9 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Letter to the Director</span>"
      "titulo" => "Alpha-1 Antitrypsin Deficiency Severe and No Severe&#46; Is It Benefit or Risk&#63;"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "731"
          "paginaFinal" => "732"
        ]
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Jos&#233; Mar&#237;a Hern&#225;ndez P&#233;rez, Claudia Vivian L&#243;pez Charry"
          "autores" => array:2 [
            0 => array:2 [
              "nombre" => "Jos&#233; Mar&#237;a"
              "apellidos" => "Hern&#225;ndez P&#233;rez"
            ]
            1 => array:2 [
              "nombre" => "Claudia Vivian"
              "apellidos" => "L&#243;pez Charry"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289622004446?idApp=UINPBA00003Z"
    "url" => "/03002896/0000005800000010/v2_202302271800/S0300289622004446/v2_202302271800/en/main.assets"
  ]
  "itemAnterior" => array:18 [
    "pii" => "S0300289622003398"
    "issn" => "03002896"
    "doi" => "10.1016/j.arbres.2022.05.004"
    "estado" => "S300"
    "fechaPublicacion" => "2022-10-01"
    "aid" => "3115"
    "copyright" => "SEPAR"
    "documento" => "simple-article"
    "crossmark" => 1
    "subdocumento" => "cor"
    "cita" => "Arch Bronconeumol. 2022;58:727-8"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:1 [
      "total" => 0
    ]
    "en" => array:10 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Letter to the Director</span>"
      "titulo" => "Why Use Aprepitant Only as a Cough Suppressant in Lung Cancer When at Higher Doses it Could Also Exert an Antitumor Action&#63;"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "727"
          "paginaFinal" => "728"
        ]
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:7 [
          "identificador" => "fig0005"
          "etiqueta" => "Fig&#46; 1"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "gr1.jpeg"
              "Alto" => 1621
              "Ancho" => 2508
              "Tamanyo" => 282999
            ]
          ]
          "descripcion" => array:1 [
            "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Lung cancer &#40;LC&#41; patients&#58; substance P &#40;SP&#41;&#44; via the neurokinin-1 receptor &#40;NK-1R&#41;&#44; promotes cough and tumor progression&#46; The NK-1R antagonist aprepitant could exert a dual therapeutic effect in these patients&#58; cough suppressant and antitumor action&#46;</p>"
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Miguel Mu&#241;oz, Miguel E&#46; Mu&#241;oz, Ferran Morell, Rafael Cove&#241;as"
          "autores" => array:4 [
            0 => array:2 [
              "nombre" => "Miguel"
              "apellidos" => "Mu&#241;oz"
            ]
            1 => array:2 [
              "nombre" => "Miguel E&#46;"
              "apellidos" => "Mu&#241;oz"
            ]
            2 => array:2 [
              "nombre" => "Ferran"
              "apellidos" => "Morell"
            ]
            3 => array:2 [
              "nombre" => "Rafael"
              "apellidos" => "Cove&#241;as"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289622003398?idApp=UINPBA00003Z"
    "url" => "/03002896/0000005800000010/v2_202302271800/S0300289622003398/v2_202302271800/en/main.assets"
  ]
  "en" => array:12 [
    "idiomaDefecto" => true
    "cabecera" => "<span class="elsevierStyleTextfn">Letter to the Editor</span>"
    "titulo" => "Medium- and Long-Term Consequences of SARS-CoV-2 Infection on COPD Patients"
    "tieneTextoCompleto" => true
    "saludo" => "To the Director&#44;"
    "paginas" => array:1 [
      0 => array:2 [
        "paginaInicial" => "729"
        "paginaFinal" => "730"
      ]
    ]
    "autores" => array:1 [
      0 => array:4 [
        "autoresLista" => "Juan Marco Figueira-Gon&#231;alves, Rafael Golpe"
        "autores" => array:2 [
          0 => array:4 [
            "nombre" => "Juan Marco"
            "apellidos" => "Figueira-Gon&#231;alves"
            "email" => array:1 [
              0 => "juanmarcofigueira@gmail.com"
            ]
            "referencia" => array:3 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff0005"
              ]
              1 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">b</span>"
                "identificador" => "aff0010"
              ]
              2 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">&#42;</span>"
                "identificador" => "cor0005"
              ]
            ]
          ]
          1 => array:3 [
            "nombre" => "Rafael"
            "apellidos" => "Golpe"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">c</span>"
                "identificador" => "aff0015"
              ]
            ]
          ]
        ]
        "afiliaciones" => array:3 [
          0 => array:3 [
            "entidad" => "Pneumology and Thoracic Surgery Service&#44; University Hospital Nuestra Se&#241;ora de Candelaria&#44; Santa Cruz de Tenerife&#44; Spain"
            "etiqueta" => "a"
            "identificador" => "aff0005"
          ]
          1 => array:3 [
            "entidad" => "University Institute of Tropical Disease and Public Health of the Canary Islands&#44; University of La Laguna&#44; Santa Cruz de Tenerife&#44; Spain"
            "etiqueta" => "b"
            "identificador" => "aff0010"
          ]
          2 => array:3 [
            "entidad" => "Pneumology Service&#44; University Hospital Lucus Augusti&#44; Lugo&#44; Spain"
            "etiqueta" => "c"
            "identificador" => "aff0015"
          ]
        ]
        "correspondencia" => array:1 [
          0 => array:3 [
            "identificador" => "cor0005"
            "etiqueta" => "&#8270;"
            "correspondencia" => "Corresponding author&#46;"
          ]
        ]
      ]
    ]
    "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">We have read with interest the article by Chiner-Vives et al&#46;<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">1</span></a> on the impact of coronavirus disease-2019 &#40;COVID-19&#41; on previous respiratory diseases&#46; As the authors mention&#44; current evidence indicates that chronic obstructive pulmonary disease &#40;COPD&#41; patients are at increased risk of suffering an infection by severe acute respiratory syndrome coronavirus-2 &#40;SARS-CoV-2&#41; and are more likely to undergo a serious form of the infection requiring hospitalization&#46; However&#44; there is uncertainty about the medium- and long-term consequences of SARS-CoV-2 infection in this population&#46; There are reasons to speculate that COPD patients might be particularly susceptible to late sequelae from COVID-19&#46; About 30&#37; of patients with COVID-19 may suffer from post-COVID syndrome&#44; or &#8220;long COVID&#8221; and this percentage may reach 50&#37; of patients who suffered a serious illness that required hospital admission&#46;<a class="elsevierStyleCrossRef" href="#bib0035"><span class="elsevierStyleSup">2</span></a> Therefore&#44; it is plausible that COPD patients could not only suffer from a more severe acute form of the disease&#44; but are also at risk of persistent symptoms&#46; Long COVID manifestations include dyspnea&#44; lower limbs weakness&#44; arthromyalgia and fatigue&#44;<a class="elsevierStyleCrossRef" href="#bib0035"><span class="elsevierStyleSup">2</span></a> and COPD itself is related to these symptoms&#46; The coexistence of both diseases could possibly multiply their effects and impact on dimensions of illness with a demonstrated influence on quality of life and survival&#44; such as physical activity&#46; In fact&#44; COPD patients reduced their activity during COVID lockdowns&#44; with the consequence of a decreased ability to perform daily activities and aggravation of mood disorders&#46;<a class="elsevierStyleCrossRef" href="#bib0040"><span class="elsevierStyleSup">3</span></a> Long COVID could only worsen these outcomes&#46; Regarding mood disorders&#44; depression can appear in up to 25&#37; of subjects 9 months after COVID-19&#46;<a class="elsevierStyleCrossRef" href="#bib0035"><span class="elsevierStyleSup">2</span></a> It is credible that pre-existing depression can worsen after SARS-CoV-2 infection&#44; and this is a common comorbidity in COPD that influences its natural history in aspects as important as the incidence of exacerbations&#46;<a class="elsevierStyleCrossRef" href="#bib0045"><span class="elsevierStyleSup">4</span></a> Furthermore&#44; COPD exacerbations are linked to an increased risk of delayed cardiovascular events&#46; A recent study found that&#44; among patients who reported symptoms of acute respiratoy illness and who were tested for SARS-CoV-2 infection&#44; frequent and prolonged alterations in resting heart rate were found in individuals with COVID-19&#44; compared to COVID-19 negative subjects&#46;<a class="elsevierStyleCrossRef" href="#bib0050"><span class="elsevierStyleSup">5</span></a> This raises concern that COPD exacerbations caused by SARS-CoV-2 infection may further increase the risk of cardiovascular adverse effects&#46;</p><p id="par0010" class="elsevierStylePara elsevierViewall">It should be noted that COVID-19 vaccination has radically changed the natural history of the disease and&#44; therefore&#44; the current evidence mentioned in the previous paragraph must be interpreted with caution in the new global situation of the pandemic&#46; However&#44; reinfections with emerging variants of SARS-CoV-2 are common among vaccinated individuals and will be a concern for COPD patients in the foreseeable future&#46; Although COVID-19 is less severe in vaccinated people&#44; it remains to be clarified whether vaccination will reduce the risk of SARS-Cov-2 infection in COPD to the same extent as in people without COPD&#46; Furthermore&#44; we do not know yet the potential impact of COVID-19 on the effectiveness of current therapies used to prevent COPD exacerbations&#46; Until more evidence is available&#44; clinicians should carefully monitor COPD patients after COVID-19&#44; taking into account the risk of both respiratory and multisystem adverse effects&#46;</p><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Authors&#8217; contribution</span><p id="par0015" class="elsevierStylePara elsevierViewall">All authors have made substantial contributions to the intellectual content and manuscript design and drafting&#46;</p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Ethical approval</span><p id="par0020" class="elsevierStylePara elsevierViewall">All authors gave their approval to the final version of the manuscript and declare to have met the requirements for authorship&#46;</p></span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0015">Funding</span><p id="par0025" class="elsevierStylePara elsevierViewall">No financial support has been received for conducting the study or drafting the manuscript&#46;</p></span><span id="sec0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0020">Conflict of interest</span><p id="par0030" class="elsevierStylePara elsevierViewall">The authors declare not to have any direct or indirect conflict of interest related to the manuscript contents&#46;</p></span></span>"
    "textoCompletoSecciones" => array:1 [
      "secciones" => array:5 [
        0 => array:2 [
          "identificador" => "sec0005"
          "titulo" => "Authors&#8217; contribution"
        ]
        1 => array:2 [
          "identificador" => "sec0010"
          "titulo" => "Ethical approval"
        ]
        2 => array:2 [
          "identificador" => "sec0015"
          "titulo" => "Funding"
        ]
        3 => array:2 [
          "identificador" => "sec0020"
          "titulo" => "Conflict of interest"
        ]
        4 => array:1 [
          "titulo" => "References"
        ]
      ]
    ]
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "bibliografia" => array:2 [
      "titulo" => "References"
      "seccion" => array:1 [
        0 => array:2 [
          "identificador" => "bibs0015"
          "bibliografiaReferencia" => array:5 [
            0 => array:3 [
              "identificador" => "bib0030"
              "etiqueta" => "1"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Short and long-term impact of COVID-19 infection on previous respiratory diseases"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "E&#46; Chiner-Vives"
                            1 => "R&#46; Cordovilla-P&#233;rez"
                            2 => "D&#46; de la Rosa-Carrillo"
                            3 => "M&#46; Garc&#237;a-Clemente"
                            4 => "J&#46;L&#46; Izquierdo-Alonso"
                            5 => "R&#46; Otero-Candelera"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:2 [
                        "tituloSerie" => "Arch Bronconeumol"
                        "fecha" => "2022"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib0035"
              "etiqueta" => "2"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Global prevalence of post COVID-19 condition or long COVID&#58; a meta-analysis and systematic review"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "C&#46; Chen"
                            1 => "S&#46;R&#46; Haupert"
                            2 => "L&#46; Zimmermann"
                            3 => "X&#46; Shi"
                            4 => "L&#46;G&#46; Fritsche"
                            5 => "B&#46; Mukherjee"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:3 [
                        "tituloSerie" => "J Infect Dis"
                        "fecha" => "2022"
                        "paginaInicial" => "jiac136"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib0040"
              "etiqueta" => "3"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "COPD in the time of COVID-19&#58; an analysis of acute exacerbations and reported behavioural changes in patients with COPD"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "H&#46; McAuley"
                            1 => "K&#46; Hadley"
                            2 => "O&#46; Elneima"
                            3 => "C&#46;E&#46; Brightling"
                            4 => "R&#46;A&#46; Evans"
                            5 => "M&#46;C&#46; Steiner"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1183/23120541.00718-2020"
                      "Revista" => array:6 [
                        "tituloSerie" => "ERJ Open Res"
                        "fecha" => "2021"
                        "volumen" => "7"
                        "paginaInicial" => "00718"
                        "paginaFinal" => "2020"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/33527075"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib0045"
              "etiqueta" => "4"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Impact of anxiety and depression on the prognosis of copd exacerbations"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "M&#46;G&#46; Sandra"
                            1 => "G&#46;S&#46; Mar&#237;a-Teresa"
                            2 => "C&#46; Jos&#233;-Mart&#237;n"
                            3 => "S&#46; Francisco-Javier"
                            4 => "C&#46;&#193;&#46; Ux&#237;o"
                            5 => "D&#46;O&#46; Liliana"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1186/s12890-022-01934-y"
                      "Revista" => array:5 [
                        "tituloSerie" => "BMC Pulm Med"
                        "fecha" => "2022"
                        "volumen" => "22"
                        "paginaInicial" => "169"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/35488330"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bib0050"
              "etiqueta" => "5"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Assessment of prolonged physiological and behavioral changes associated with COVID-19 infection"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "J&#46;M&#46; Radin"
                            1 => "G&#46; Quer"
                            2 => "E&#46; Ramos"
                            3 => "K&#46; Baca-Motes"
                            4 => "M&#46; Gadaleta"
                            5 => "E&#46;J&#46; Topol"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1001/jamanetworkopen.2021.15959"
                      "Revista" => array:5 [
                        "tituloSerie" => "JAMA Netw Open"
                        "fecha" => "2021"
                        "volumen" => "4"
                        "paginaInicial" => "e2115959"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/34232306"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "en"
  "url" => "/03002896/0000005800000010/v2_202302271800/S0300289622004409/v2_202302271800/en/main.assets"
  "Apartado" => array:4 [
    "identificador" => "94562"
    "tipo" => "SECCION"
    "es" => array:2 [
      "titulo" => "Letters to the Director"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "es"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/03002896/0000005800000010/v2_202302271800/S0300289622004409/v2_202302271800/en/main.pdf?idApp=UINPBA00003Z&text.app=https://archbronconeumol.org/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289622004409?idApp=UINPBA00003Z"
]
Article information
ISSN: 03002896
Original language: English
The statistics are updated each day
Year/Month Html Pdf Total
2024 November 13 4 17
2024 October 108 19 127
2024 September 142 22 164
2024 August 151 38 189
2024 July 153 22 175
2024 June 158 29 187
2024 May 181 33 214
2024 April 133 25 158
2024 March 120 18 138
2024 February 144 30 174
2024 January 172 29 201
2023 December 267 32 299
2023 November 263 45 308
2023 October 561 53 614
2023 September 319 69 388
2023 August 270 62 332
2023 July 348 47 395
2023 June 6647 40 6687
2023 May 372 36 408
2023 April 255 48 303
2023 March 328 65 393
2023 February 307 61 368
2023 January 308 67 375
2022 December 336 71 407
2022 November 550 131 681
2022 October 704 134 838
2022 September 390 40 430
2022 August 362 26 388
2022 July 255 19 274
2022 June 321 17 338
Show all

Follow this link to access the full text of the article

Archivos de Bronconeumología

Are you a health professional able to prescribe or dispense drugs?