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          "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">&#40;A&#8211;B<span class="elsevierStyleBold">&#41;</span> Pre-operative CT image showing bilateral pulmonary nodules&#46; A&#41; Subpleural pulmonary nodule in the anterior segment of the right upper lobe&#46; B&#41; Left lower lobe pulmonary nodules&#46; &#40;C&#8211;F&#41; Histologic images of the pulmonary nodule resected during surgery&#46; C&#41; Pulmonary parenchyma and bronchiole observed on the left&#44; and on the right a nodule consisting of cells that appear light-colored at this magnification&#44; with an incomplete lymphocytic rim &#40;a foreign body granuloma variant&#41;&#46; D&#41; At higher magnification&#44; these cells are seen to be histiocytic with a large &#8220;blank&#8221;&#44; i&#46;e&#46; empty cytoplasm&#44; because the silicone dissolves as it is processed&#44; leaving a hollow space&#46; E&#41; Foreign body granuloma in the lung parenchyma near a vein&#46; F&#41; At higher magnification&#44; the typical histiocytes and multinucleated giant cells are seen in more detail&#46;</p>"
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    "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">A 52-year-old woman with stage IA infiltrating lobular breast cancer underwent right radical mastectomy with immediate reconstruction&#46; In her oncological follow-up&#44; a cannonball radiological pattern was observed &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>&#41;&#44; so one of the nodules was biopsied for histologic typing&#46;</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><p id="par0010" class="elsevierStylePara elsevierViewall">Atypical right S3 segmentectomy was performed by video-assisted thoracoscopy and&#44; surprisingly&#44; an intra-pulmonary nodule was reported&#44; consisting of intra-cytoplasmic oily material with a lymphocytic rim&#44; with the presence of giant cell microgranulomas with intravascular oily material&#44; consistent with a diagnosis of pulmonary siliconoma &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>&#41;&#46;</p><p id="par0015" class="elsevierStylePara elsevierViewall">A conservative approach was taken with regard to the nodules &#40;as resection would have required a lobectomy&#41;&#44; with close follow-up and replacement of the silicone implant&#44; which was assumed to have ruptured&#46; No changes in the lung lesions were observed in successive follow-ups&#46;</p><p id="par0020" class="elsevierStylePara elsevierViewall">In 1964&#44; Winer first described siliconoma &#40;foreign body granulomatous reaction caused by liquid silicones in the tissues and surrounding fibrosis&#41;&#46; Late complications&#44; such as local siliconomas or lymphadenopathies&#44; are widely described&#44; while peripheral spread to subcutaneous tissue and the existence of intrapulmonary siliconomas are extremely rare&#46; We have only found reports by Mu&#241;iz et al&#46;<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a> and Dragu et al&#46;<a class="elsevierStyleCrossRef" href="#bib0010"><span class="elsevierStyleSup">2</span></a>&#44; which&#44; unlike our case&#44; were single lung lesions&#46;</p><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Conflict of interests</span><p id="par0025" class="elsevierStylePara elsevierViewall">All authors declare no conflict of interests&#46;</p><p id="par0030" class="elsevierStylePara elsevierViewall">This study received no specific grants from public sector agencies&#44; the commercial sector&#44; or from non-profit organizations&#46;</p></span></span>"
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Clinical Image
Lung siliconoma, an etiology to consider
Siliconoma pulmonar, una etiología a tener en cuenta
Fernando Cózar Bernal
Corresponding author
fcozarbernal@gmail.com

Corresponding author.
, Julia González Fernández, Juan Carlos Girón Arjona
Servicio de Cirugía Torácica, Hospital Universitario Virgen Macarena, Sevilla, Spain
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    "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">A 52-year-old woman with stage IA infiltrating lobular breast cancer underwent right radical mastectomy with immediate reconstruction&#46; In her oncological follow-up&#44; a cannonball radiological pattern was observed &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>&#41;&#44; so one of the nodules was biopsied for histologic typing&#46;</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><p id="par0010" class="elsevierStylePara elsevierViewall">Atypical right S3 segmentectomy was performed by video-assisted thoracoscopy and&#44; surprisingly&#44; an intra-pulmonary nodule was reported&#44; consisting of intra-cytoplasmic oily material with a lymphocytic rim&#44; with the presence of giant cell microgranulomas with intravascular oily material&#44; consistent with a diagnosis of pulmonary siliconoma &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>&#41;&#46;</p><p id="par0015" class="elsevierStylePara elsevierViewall">A conservative approach was taken with regard to the nodules &#40;as resection would have required a lobectomy&#41;&#44; with close follow-up and replacement of the silicone implant&#44; which was assumed to have ruptured&#46; No changes in the lung lesions were observed in successive follow-ups&#46;</p><p id="par0020" class="elsevierStylePara elsevierViewall">In 1964&#44; Winer first described siliconoma &#40;foreign body granulomatous reaction caused by liquid silicones in the tissues and surrounding fibrosis&#41;&#46; Late complications&#44; such as local siliconomas or lymphadenopathies&#44; are widely described&#44; while peripheral spread to subcutaneous tissue and the existence of intrapulmonary siliconomas are extremely rare&#46; We have only found reports by Mu&#241;iz et al&#46;<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a> and Dragu et al&#46;<a class="elsevierStyleCrossRef" href="#bib0010"><span class="elsevierStyleSup">2</span></a>&#44; which&#44; unlike our case&#44; were single lung lesions&#46;</p><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Conflict of interests</span><p id="par0025" class="elsevierStylePara elsevierViewall">All authors declare no conflict of interests&#46;</p><p id="par0030" class="elsevierStylePara elsevierViewall">This study received no specific grants from public sector agencies&#44; the commercial sector&#44; or from non-profit organizations&#46;</p></span></span>"
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          "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">&#40;A&#8211;B<span class="elsevierStyleBold">&#41;</span> Pre-operative CT image showing bilateral pulmonary nodules&#46; A&#41; Subpleural pulmonary nodule in the anterior segment of the right upper lobe&#46; B&#41; Left lower lobe pulmonary nodules&#46; &#40;C&#8211;F&#41; Histologic images of the pulmonary nodule resected during surgery&#46; C&#41; Pulmonary parenchyma and bronchiole observed on the left&#44; and on the right a nodule consisting of cells that appear light-colored at this magnification&#44; with an incomplete lymphocytic rim &#40;a foreign body granuloma variant&#41;&#46; D&#41; At higher magnification&#44; these cells are seen to be histiocytic with a large &#8220;blank&#8221;&#44; i&#46;e&#46; empty cytoplasm&#44; because the silicone dissolves as it is processed&#44; leaving a hollow space&#46; E&#41; Foreign body granuloma in the lung parenchyma near a vein&#46; F&#41; At higher magnification&#44; the typical histiocytes and multinucleated giant cells are seen in more detail&#46;</p>"
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Article information
ISSN: 03002896
Original language: English
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