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array:23 [ "pii" => "S0300289621001964" "issn" => "03002896" "doi" => "10.1016/j.arbres.2021.06.012" "estado" => "S300" "fechaPublicacion" => "2022-06-01" "aid" => "2873" "copyright" => "SEPAR" "copyrightAnyo" => "2021" "documento" => "article" "crossmark" => 1 "subdocumento" => "sco" "cita" => "Arch Bronconeumol. 2022;58:507-8" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "itemSiguiente" => array:18 [ "pii" => "S0300289621001988" "issn" => "03002896" "doi" => "10.1016/j.arbres.2021.06.014" "estado" => "S300" "fechaPublicacion" => "2022-06-01" "aid" => "2875" "copyright" => "SEPAR" "documento" => "article" "crossmark" => 1 "subdocumento" => "sco" "cita" => "Arch Bronconeumol. 2022;58:509" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "en" => array:10 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Clinical Image</span>" "titulo" => "Rebound Thymic Hyperplasia Secondary to Surgical Therapy of Parotid Tumor" "tienePdf" => "en" "tieneTextoCompleto" => "en" "paginas" => array:1 [ 0 => array:1 [ "paginaInicial" => "509" ] ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0005" "etiqueta" => "Fig. 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 2082 "Ancho" => 3823 "Tamanyo" => 799897 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">(A, C, and E) Thorax CT scans during presentation demonstrate normal mediastinum structures. (B, D, and F) After three months surgical treatment, control CT scans reveal rebound thymic hyperplasia (asterisks) in the anterior mediastinum.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Veysel Ayyildiz, Ali Koksal, Yasemin Ogul" "autores" => array:3 [ 0 => array:2 [ "nombre" => "Veysel" "apellidos" => "Ayyildiz" ] 1 => array:2 [ "nombre" => "Ali" "apellidos" => "Koksal" ] 2 => array:2 [ "nombre" => "Yasemin" "apellidos" => "Ogul" ] ] ] ] ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289621001988?idApp=UINPBA00003Z" "url" => "/03002896/0000005800000006/v2_202212170815/S0300289621001988/v2_202212170815/en/main.assets" ] "itemAnterior" => array:17 [ "pii" => "S0300289621001848" "issn" => "03002896" "doi" => "10.1016/j.arbres.2021.06.002" "estado" => "S300" "fechaPublicacion" => "2022-06-01" "aid" => "2861" "documento" => "article" "crossmark" => 1 "subdocumento" => "sco" "cita" => "Arch Bronconeumol. 2022;58:506" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "en" => array:10 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Clinical Image</span>" "titulo" => "Unexpected Paratracheal Opacity" "tienePdf" => "en" "tieneTextoCompleto" => "en" "paginas" => array:1 [ 0 => array:1 [ "paginaInicial" => "506" ] ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:6 [ "identificador" => "fig0005" "etiqueta" => "Fig. 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 1666 "Ancho" => 1667 "Tamanyo" => 174448 ] ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Laura Núñez-García, María de los Ángeles Zambrano-Chacón, Felipe Villar-Álvarez" "autores" => array:3 [ 0 => array:2 [ "nombre" => "Laura" "apellidos" => "Núñez-García" ] 1 => array:2 [ "nombre" => "María de los Ángeles" "apellidos" => "Zambrano-Chacón" ] 2 => array:2 [ "nombre" => "Felipe" "apellidos" => "Villar-Álvarez" ] ] ] ] ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289621001848?idApp=UINPBA00003Z" "url" => "/03002896/0000005800000006/v2_202212170815/S0300289621001848/v2_202212170815/en/main.assets" ] "en" => array:13 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Clinical Image</span>" "titulo" => "Exuberant Paraseptal Emphysema Associated With Pulmonary Alveolar Microlithiasis: 12 Years of Evolution" "tieneTextoCompleto" => true "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "507" "paginaFinal" => "508" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "Edson Marchiori, Rosana Souza Rodrigues, Miriam Menna Barreto" "autores" => array:3 [ 0 => array:4 [ "nombre" => "Edson" "apellidos" => "Marchiori" "email" => array:1 [ 0 => "edmarchiori@gmail.com" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor0005" ] ] ] 1 => array:3 [ "nombre" => "Rosana" "apellidos" => "Souza Rodrigues" "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] ] 2 => array:3 [ "nombre" => "Miriam" "apellidos" => "Menna Barreto" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] ] ] ] "afiliaciones" => array:2 [ 0 => array:3 [ "entidad" => "Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil" "etiqueta" => "a" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "Instituto D’Or de Pesquisa e Ensino, Rio de Janeiro, Brazil" "etiqueta" => "b" "identificador" => "aff0010" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0005" "etiqueta" => "Fig. 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 917 "Ancho" => 1500 "Tamanyo" => 314703 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Chest computed tomography axial image obtained with lung window setting (A), mediastinal window setting (B) and coronal (C) reformatted reconstruction using minimum intensity projection (MinIP) showing extensive paraseptal emphysema and pulmonary calcifications predominating in the paramediastinal regions. Note also signs of interstitial emphysema (especially in A). In D, an axial scan with lung window setting obtained 12 years previously demonstrating incipient paraseptal emphysema. In E, a photomicrograph of a pulmonary biopsy specimen showing laminated microliths filling the alveolar spaces (original magnification<span class="elsevierStyleHsp" style=""></span>×<span class="elsevierStyleHsp" style=""></span>100; hematoxylin and eosin stain).</p>" ] ] ] "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">A 32-year-old non-smoking man with pulmonary alveolar microlithiasis (PAM) was admitted with cough and dyspnea. Laboratory test results were unremarkable. Chest computed tomography (CT) revealed paraseptal emphysema compromising the entire extent of the subpleural pulmonary parenchyma, and calcifications predominating in the paramediastinal regions (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>A–C). CT performed 12 years previously showed similar alterations, to a lesser extent (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>D). Pulmonary biopsy performed 12 years previously showed multiple laminated microliths filling the alveolar spaces compatible with PAM (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>E). The patient was managed on an outpatient basis.</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><p id="par0010" class="elsevierStylePara elsevierViewall">PAM is a rare autosomal recessive disorder characterized by the intra-alveolar accumulation of spherical calcified concretions (called calciferites or microliths) in the absence of any known calcium metabolism disorder. Most patients with PAM are asymptomatic at the time of diagnosis, and the disease is usually detected incidentally during routine examinations. CT studies of PAM frequently demonstrate the presence of subpleural cysts with diameters of 5–10<span class="elsevierStyleHsp" style=""></span>mm, which may represent early lung fibrosis. These cysts correspond to the “black pleura” chest-X ray sign. The CT findings of PAM are so characteristic that additional diagnostic investigation is usually unnecessary, especially in patients with other family members with PAM.<a class="elsevierStyleCrossRefs" href="#bib0015"><span class="elsevierStyleSup">1,2</span></a></p><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Conflicts of interest</span><p id="par0015" class="elsevierStylePara elsevierViewall">The authors declare that they have no conflicts of interest to express.</p></span></span>" "textoCompletoSecciones" => array:1 [ "secciones" => array:2 [ 0 => array:2 [ "identificador" => "sec0005" "titulo" => "Conflicts of interest" ] 1 => array:1 [ "titulo" => "References" ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "multimedia" => array:1 [ 0 => array:7 [ "identificador" => "fig0005" "etiqueta" => "Fig. 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 917 "Ancho" => 1500 "Tamanyo" => 314703 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Chest computed tomography axial image obtained with lung window setting (A), mediastinal window setting (B) and coronal (C) reformatted reconstruction using minimum intensity projection (MinIP) showing extensive paraseptal emphysema and pulmonary calcifications predominating in the paramediastinal regions. Note also signs of interstitial emphysema (especially in A). In D, an axial scan with lung window setting obtained 12 years previously demonstrating incipient paraseptal emphysema. In E, a photomicrograph of a pulmonary biopsy specimen showing laminated microliths filling the alveolar spaces (original magnification<span class="elsevierStyleHsp" style=""></span>×<span class="elsevierStyleHsp" style=""></span>100; hematoxylin and eosin stain).</p>" ] ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0015" "bibliografiaReferencia" => array:2 [ 0 => array:3 [ "identificador" => "bib0015" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Pulmonary alveolar microlithiasis State-of-the-art review" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "F.A. Francisco" 1 => "J.L. Pereira e Silva" 2 => "B. Hochhegger" 3 => "G. Zanetti" 4 => "E. Marchiori" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.rmed.2012.10.014" "Revista" => array:6 [ "tituloSerie" => "Respir Med" "fecha" => "2013" "volumen" => "107" "paginaInicial" => "1" "paginaFinal" => "9" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/23183116" "web" => "Medline" ] ] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib0020" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "High resolution computed tomographic features of pulmonary alveolar microlithiasis" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "O. Deniz" 1 => "F. Ors" 2 => "E. Tozkoparan" 3 => "A. Ozcan" 4 => "S. Gumus" 5 => "U. Bozlar" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.ejrad.2005.01.010" "Revista" => array:6 [ "tituloSerie" => "Eur J Radiol" "fecha" => "2005" "volumen" => "55" "paginaInicial" => "452" "paginaFinal" => "460" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16129256" "web" => "Medline" ] ] ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/03002896/0000005800000006/v2_202212170815/S0300289621001964/v2_202212170815/en/main.assets" "Apartado" => array:4 [ "identificador" => "93864" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Clinical Images" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/03002896/0000005800000006/v2_202212170815/S0300289621001964/v2_202212170815/en/main.pdf?idApp=UINPBA00003Z&text.app=https://archbronconeumol.org/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289621001964?idApp=UINPBA00003Z" ]
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