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(C) 15-mm lobulated soft tissue mass of almost excised lipoma.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "René Agustín Flores-Franco, Luis Fernando González-Calzadillas, Stephanie Cota-Castro" "autores" => array:3 [ 0 => array:2 [ "nombre" => "René Agustín" "apellidos" => "Flores-Franco" ] 1 => array:2 [ "nombre" => "Luis Fernando" "apellidos" => "González-Calzadillas" ] 2 => array:2 [ "nombre" => "Stephanie" "apellidos" => "Cota-Castro" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "en" => array:9 [ "pii" => "S0300289617303939" "doi" => "10.1016/j.arbres.2017.10.004" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289617303939?idApp=UINPBA00003Z" ] ] "EPUB" => 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"en" "paginas" => array:1 [ 0 => array:1 [ "paginaInicial" => "236" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Detección molecular del alelo F52del frecuente en la deficiencia de alfa-1-antitripsina" ] ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Francisco Martínez Bugallo, Juan Marco Figueira Gonçalves, María Dolores Martín Martínez" "autores" => array:3 [ 0 => array:2 [ "nombre" => "Francisco" "apellidos" => "Martínez Bugallo" ] 1 => array:2 [ "nombre" => "Juan Marco" "apellidos" => "Figueira Gonçalves" ] 2 => array:2 [ "nombre" => "María Dolores" "apellidos" => "Martín Martínez" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "en" => array:9 [ "pii" => "S1579212918300569" "doi" => "10.1016/j.arbr.2017.10.018" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false 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class="elsevierStyleTextfn">Scientific Letter</span>" "titulo" => "Effects of Ivacaftor in Three Pediatric Siblings With Cystic Fibrosis Carrying the Mutations G551D And F508del" "tienePdf" => "en" "tieneTextoCompleto" => "en" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "232" "paginaFinal" => "234" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Efectos del ivacaftor en tres hermanos con fibrosis quística portadores de las mutaciones G551D y F508del" ] ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0005" "etiqueta" => "Fig. 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 1461 "Ancho" => 2167 "Tamanyo" => 155426 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Courses of fecal elastase in stool before and since introduction of CFTR modulator therapy (arrows) with ivacaftor (IVA) (<200<span class="elsevierStyleHsp" style=""></span>μg/g of stool: reduced elastase; 200 to <500<span class="elsevierStyleHsp" style=""></span>μg/g: borderline values; ≥500<span class="elsevierStyleHsp" style=""></span>μg/g: normal).</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Jochen G. 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"apellidos" => "Mainz" ] 1 => array:2 [ "nombre" => "Christin" "apellidos" => "Arnold" ] 2 => array:2 [ "nombre" => "Julia" "apellidos" => "Hentschel" ] 3 => array:2 [ "nombre" => "Harold" "apellidos" => "Tabori" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "en" => array:9 [ "pii" => "S1579212918300545" "doi" => "10.1016/j.arbr.2017.09.013" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1579212918300545?idApp=UINPBA00003Z" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289617303162?idApp=UINPBA00003Z" "url" => "/03002896/0000005400000004/v2_201804150418/S0300289617303162/v2_201804150418/en/main.assets" ] "en" => array:14 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Letter to the Editor</span>" "titulo" => "Successful Endoscopic Resection of an Endobronchial Lipoma Using a Percutaneous Gastrostomy Snare Device" "tieneTextoCompleto" => true "saludo" => "<span class="elsevierStyleItalic">Dear Editor:</span>" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "235" "paginaFinal" => "236" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "René Agustín Flores-Franco, Luis Fernando González-Calzadillas, Stephanie Cota-Castro" "autores" => array:3 [ 0 => array:4 [ "nombre" => "René Agustín" "apellidos" => "Flores-Franco" "email" => array:1 [ 0 => "rflores99@prontomail.com" ] "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor0005" ] ] ] 1 => array:2 [ "nombre" => "Luis Fernando" "apellidos" => "González-Calzadillas" ] 2 => array:2 [ "nombre" => "Stephanie" "apellidos" => "Cota-Castro" ] ] "afiliaciones" => array:1 [ 0 => array:2 [ "entidad" => "Internal Medicine and Thoracic Surgery Divisions, Regional General Hospital “Dr Salvador Zubirán Anchondo”, Chihuahua, Chih., Mexico" "identificador" => "aff0005" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Resección endoscópica con éxito de un lipoma endobronquial utilizando un dispositivo percutáneo de asa para gastrostomía" ] ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 725 "Ancho" => 2083 "Tamanyo" => 152520 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">(A) Computed tomography showing the endobronchial lipoma blocking the right main bronchus (white arrow). (B) Our snare mounted in the flexible bronchoscope. (C) 15-mm lobulated soft tissue mass of almost excised lipoma.</p>" ] ] ] "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">Endobronchial lipomas are rare benign tumors which are amenable to endoscopic management both for diagnosis and treatment. Excluding those cases that merits surgical treatment, endoscopic mechanical debulking in conjunction with other techniques actually are the preferred method of treatment as it results in complete resection and preserve lung parenchyma.<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">1</span></a> These tumors are poorly vascularized and patients rarely present with hemoptysis, and if that is the case, it has been mainly attributed to post obstructive pneumonia or bronchiectasis rather than the tumor itself.<a class="elsevierStyleCrossRef" href="#bib0035"><span class="elsevierStyleSup">2</span></a> With all of this in mind, we recently decided to resect a previously histologically confirmed endobronchial pedunculated lipoma which obstructs the intermediary bronchus (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>A) from a 69-year old never smoker man who has a history of recurrent right lower pneumonia and with the aid of a cold snare device (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>B) intended for percutaneous endoscopic gastrostomy (Cook Medical). In a similar way as described by other authors using a polypectomy electric snare,<a class="elsevierStyleCrossRef" href="#bib0040"><span class="elsevierStyleSup">3</span></a> we grasp the endobronchial lipoma with the snare introduced in the 2.6<span class="elsevierStyleHsp" style=""></span>mm working channel of an Olympus LF-TP flexible fiberscope which in turn was placed through the rigid bronchoscope to the right main bronchus. The open snare was carefully positioned around the lipoma taking care to grasp its pedicle. Once the snare has been closed, a clean cut was obtained under the large part of the lipoma with minimal blood loss. The resected lipoma and the scarce residual lipomatous tissue were finally removed with a large forceps (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>C).</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><p id="par0010" class="elsevierStylePara elsevierViewall">The successful use of an electrosurgical snare to resect endobronchial lipoma has already been described by other authors,<a class="elsevierStyleCrossRefs" href="#bib0040"><span class="elsevierStyleSup">3–5</span></a> but actually there are no reports using a cold snare. Our method requires a precise diagnosis since other endobronchial lipomatous tumors that are radiologically and macroscopically very similar with lipomas are more amenable for bleeding complication.<a class="elsevierStyleCrossRef" href="#bib0035"><span class="elsevierStyleSup">2</span></a> Already corroborated the correct histopathological diagnosis, a second endoscopic procedure will be required to resect the lipoma. Our diagnosis of endobronchial lipoma was performed during a first rigid bronchoscopy and by means of large excisional biopsy that reasonably excluded other pathologies. During the second endoscopy, the gelatinous consistency of the tissue did not allow us to complete the removal of the large tumor remnant with only forceps. Endobronchial lipomas generally initiate in the submucosa and histological analysis of the lesions reveals lobes of mature fat cells, either partially or totally surrounded by a fibrous capsule without a prominent vasculature. This is the reason why in situations where conventional bronchoscopic ablative therapies are not available, an endobronchial neoplasia compatible with a lipoma could be resected with an improvised instrumentation with minimal risk of bleeding.</p><p id="par0015" class="elsevierStylePara elsevierViewall">If there is a risk of long-term recurrence of this tumor using endoscopic debulking techniques, this is an issue yet to be defined by researchers, but for the moment our main goal was to avoid recurrent post-obstructive infections and their sequelae.</p></span>" "pdfFichero" => "main.pdf" "tienePdf" => true "multimedia" => array:1 [ 0 => array:7 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 725 "Ancho" => 2083 "Tamanyo" => 152520 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">(A) Computed tomography showing the endobronchial lipoma blocking the right main bronchus (white arrow). (B) Our snare mounted in the flexible bronchoscope. (C) 15-mm lobulated soft tissue mass of almost excised lipoma.</p>" ] ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0015" "bibliografiaReferencia" => array:5 [ 0 => array:3 [ "identificador" => "bib0030" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "A multicenter retrospective study investigating the role of interventional bronchoscopic techniques in the management of endobronchial lipomas" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "A.H. Nassiri" 1 => "H. Dutau" 2 => "D. Breen" 3 => "A. Colchen" 4 => "J.J. Quiot" 5 => "B. 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Figueiredo" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Bras Pneumol" "fecha" => "2011" "volumen" => "37" "paginaInicial" => "796" "paginaFinal" => "800" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/22241038" "web" => "Medline" ] ] ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib0045" "etiqueta" => "4" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "An endobronchial lipoma successfully resected by high-frequency electric snare. A report of 2 cases" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "S. Shinohara" 1 => "T. Hanagiri" 2 => "M. Takenaka" 3 => "S. Oka" 4 => "Y. Chikaishi" 5 => "Y. Shigematsu" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "J Bronchol Interv Pulmonol" "fecha" => "2012" "volumen" => "19" "paginaInicial" => "68" "paginaFinal" => "71" ] ] ] ] ] ] 4 => array:3 [ "identificador" => "bib0050" "etiqueta" => "5" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Endobronchial lipoma causing progressive dyspnea" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "V.Dy. Rajany" 1 => "S. Patel" 2 => "K. Harris" 3 => "M.J. Mador" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.rmcr.2017.07.002" "Revista" => array:7 [ "tituloSerie" => "Respir Med Case Rep" "fecha" => "2017" "volumen" => "22" "paginaInicial" => "95" "paginaFinal" => "97" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/28736696" "web" => "Medline" ] ] "itemHostRev" => array:3 [ "pii" => "S0967586814003063" "estado" => "S300" "issn" => "09675868" ] ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/03002896/0000005400000004/v2_201804150418/S0300289617303939/v2_201804150418/en/main.assets" "Apartado" => array:4 [ "identificador" => "9222" "tipo" => "SECCION" "es" => array:2 [ "titulo" => "Letters to the Director / Cartas al Director" "idiomaDefecto" => true ] "idiomaDefecto" => "es" ] "PDF" => "https://static.elsevier.es/multimedia/03002896/0000005400000004/v2_201804150418/S0300289617303939/v2_201804150418/en/main.pdf?idApp=UINPBA00003Z&text.app=https://archbronconeumol.org/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289617303939?idApp=UINPBA00003Z" ]
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