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          "es" => "<p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">Preocupaci&#243;n por la vida sexual y motivos aducidos por los pacientes asm&#225;ticos y el grupo control&#46;</p>"
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    "textoCompleto" => "<span class="elsevierStyleSections"><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0065">Introducci&#243;n</span><p id="par0005" class="elsevierStylePara elsevierViewall">Est&#225; bien documentado que las dificultades sexuales pueden acompa&#241;ar a las enfermedades cr&#243;nicas<a class="elsevierStyleCrossRefs" href="#bib0135"><span class="elsevierStyleSup">1-4</span></a>&#46; La relaci&#243;n entre la actividad sexual y el asma se conoce desde hace a&#241;os&#44; aunque existe poca informaci&#243;n cuantitativa&#46; El concepto de que el sexo puede desencadenar una exacerbaci&#243;n asm&#225;tica no parece inveros&#237;mil y existen antecedentes descritos previamente&#46; En una carta de 1976 al peri&#243;dico <span class="elsevierStyleItalic">Lancet</span>&#44; dos investigadores&#44; Symington y Kerr&#44; describieron que la actividad sexual pod&#237;a causar asma as&#237; como rinitis<a class="elsevierStyleCrossRefs" href="#bib0155"><span class="elsevierStyleSup">5-8</span></a>&#46; Ha sido descrito que el coito puede desencadenar una exacerbaci&#243;n grave de asma que requiera acudir a departamentos de urgencias&#44; hospitalizaci&#243;n o incluso ventilaci&#243;n asistida<a class="elsevierStyleCrossRefs" href="#bib0175"><span class="elsevierStyleSup">9&#44;10</span></a>&#46;</p><p id="par0010" class="elsevierStylePara elsevierViewall">Los requerimientos f&#237;sicos de la actividad sexual podr&#237;an provocar una agudizaci&#243;n asm&#225;tica&#44; aunque para algunos autores&#44; la mera excitaci&#243;n emocional es suficiente para provocar o agravar el padecimiento previo&#46; El t&#233;rmino ingl&#233;s asma inducida por ejercicio sexual <span class="elsevierStyleItalic">&#40;sexercise induced asthma&#41;</span><a class="elsevierStyleCrossRefs" href="#bib0155"><span class="elsevierStyleSup">5-8</span></a>&#44; para algunos no es m&#225;s que una variante de asma inducida por ejercicio&#46;</p><p id="par0015" class="elsevierStylePara elsevierViewall">Sin embargo&#44; los estudios que evaluaron la calidad de vida sexual de los pacientes con asma son escasos o adolecen de dise&#241;os y metodolog&#237;a cuestionables&#46; En un estudio realizado en urgencias del Harlem Hospital Center en la ciudad de New York<a class="elsevierStyleCrossRef" href="#bib0185"><span class="elsevierStyleSup">11</span></a>&#44; los investigadores preguntaron a 356 pacientes sobre el grado en el que su asma hab&#237;a perjudicado la realizaci&#243;n de determinadas actividades&#46; De ellas&#44; la limitaci&#243;n para la actividad sexual fue la tercera mencionada con mayor frecuencia&#46; Recientemente&#44; Basar et al&#46;<a class="elsevierStyleCrossRef" href="#bib0190"><span class="elsevierStyleSup">12</span></a> encuentran disfunci&#243;n sexual en 18 pacientes con asma &#40;47&#44;4&#37;&#41; frente a 4 mujeres del grupo control &#40;20&#37;&#41;&#46; Por &#250;ltimo&#44; se ha comunicado alguna observaci&#243;n puntual de disfunci&#243;n er&#233;ctil &#40;DE&#41; en varones asm&#225;ticos<a class="elsevierStyleCrossRefs" href="#bib0195"><span class="elsevierStyleSup">13&#44;14</span></a>&#44; con la consiguiente repercusi&#243;n en las relaciones de pareja&#46;</p><p id="par0020" class="elsevierStylePara elsevierViewall">Dadas las carencias observadas nos planteamos el presente estudio con un doble objetivo&#46; Por un lado&#44; evaluar el posible impacto de la enfermedad asm&#225;tica en la vida sexual de los pacientes&#44; mujeres y varones&#44; con asma&#46; Y por otro&#44; determinar los posibles factores asociados a dicha disfunci&#243;n&#44; tales como gravedad&#44; nivel de control y comorbilidades asociadas a la enfermedad&#46;</p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0070">Material y m&#233;todos</span><p id="par0025" class="elsevierStylePara elsevierViewall">Estudio observacional&#44; transversal y multic&#233;ntrico realizado en un grupo de pacientes asm&#225;ticos de ambos sexos y mayores de 18 a&#241;os procedentes de las consultas externas de 7 hospitales terciarios espa&#241;oles&#44; elegidos de forma consecutiva&#46; El estudio fue desarrollado tras la aprobaci&#243;n de los respectivos comit&#233;s &#233;ticos locales y a todas las personas incluidas se les solicit&#243; su consentimiento por escrito para su participaci&#243;n&#46;</p><p id="par0030" class="elsevierStylePara elsevierViewall">El diagn&#243;stico de asma se realiz&#243; seg&#250;n los criterios de GEMA<a class="elsevierStyleCrossRef" href="#bib0205"><span class="elsevierStyleSup">15</span></a>&#44; atendiendo a criterios cl&#237;nicos sugestivos y obstrucci&#243;n al flujo a&#233;reo reversible documentada en al menos un estudio previo de funci&#243;n pulmonar&#46; Se evalu&#243; la gravedad de la enfermedad y el grado de control de la misma tambi&#233;n seg&#250;n los criterios de la GEMA<a class="elsevierStyleCrossRef" href="#bib0205"><span class="elsevierStyleSup">15</span></a>&#46; Junto con ello se recogieron datos sobre tabaquismo&#44; tiempo de evoluci&#243;n de la enfermedad&#44; existencia de posible asma de esfuerzo&#44; morbilidad previa &#40;exacerbaciones y hospitalizaciones en el a&#241;o previo a la inclusi&#243;n&#41;&#44; espirometr&#237;a&#44; presencia de comorbilidades &#40;rinitis&#44; poliposis nasal&#44; reflujo&#44; fibromialgia&#44; ansiedad&#44; depresi&#243;n&#44; hipertensi&#243;n arterial&#44; diabetes&#41; y el tratamiento de mantenimiento que ven&#237;an recibiendo&#46; La rinitis se clasific&#243; seg&#250;n su gravedad siguiendo los criterios de la gu&#237;a ARIA<a class="elsevierStyleCrossRef" href="#bib0210"><span class="elsevierStyleSup">16</span></a>&#46; Todos los pacientes se encontraban en periodo de estabilidad de su enfermedad asm&#225;tica&#44; que se defini&#243; como sin exacerbaci&#243;n en las 4 semanas previas a su inclusi&#243;n&#46;</p><p id="par0035" class="elsevierStylePara elsevierViewall">Se incluy&#243; un grupo control de voluntarios sanos&#44; que fue seleccionado de entre los visitantes o acompa&#241;antes de los pacientes en las mismas consultas externas de los centros participantes&#46; Fueron seleccionados para ello personas de edad similar al grupo asm&#225;tico&#44; sin enfermedad cr&#243;nica respiratoria&#44; ni comorbilidades relevantes&#46;</p><p id="par0040" class="elsevierStylePara elsevierViewall">A ambos grupos se les pregunt&#243; sobre la existencia de preocupaci&#243;n sobre su vida sexual y los motivos de esta&#46;</p><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0075">Procedimientos de estudio</span><p id="par0045" class="elsevierStylePara elsevierViewall"><ul class="elsevierStyleList" id="lis0005"><li class="elsevierStyleListItem" id="lsti0005"><span class="elsevierStyleLabel">a&#41;</span><p id="par0050" class="elsevierStylePara elsevierViewall">Estado psicol&#243;gico&#58; se administr&#243; la <span class="elsevierStyleItalic">Goldberg</span> Anxiety<span class="elsevierStyleItalic">-Depression Scale</span> &#40;GADS&#41;<a class="elsevierStyleCrossRef" href="#bib0215"><span class="elsevierStyleSup">17</span></a>&#46; El cuestionario GADS pregunta c&#243;mo los encuestados se han sentido en el &#250;ltimo mes en 9 &#237;tems de ansiedad y 9 de depresi&#243;n&#44; a los que se aplica la respuesta dicot&#243;mica &#171;s&#237;&#187; o &#171;no&#187;&#46;</p></li><li class="elsevierStyleListItem" id="lsti0010"><span class="elsevierStyleLabel">b&#41;</span><p id="par0055" class="elsevierStylePara elsevierViewall">Sexualidad&#58; en mujeres se aplic&#243; el &#205;ndice de Funci&#243;n Sexual Femenina &#40;<span class="elsevierStyleItalic">Female Sexual Function Index</span> &#91;FSFI&#93;&#41;&#44; descrito por Rosen et al&#46;<a class="elsevierStyleCrossRef" href="#bib0220"><span class="elsevierStyleSup">18</span></a>&#46; El FSFI es un cuestionario autoadministrado&#46; La paciente tiene que responder a 19 cuestiones diferentes y seleccionar en cada una de ellas una de las 6 respuestas posibles que mejor describa su situaci&#243;n durante las &#250;ltimas 4 semanas &#40;una respuesta de 0 indica que no ha habido actividad sexual&#44; una de1 indica el mayor deterioro funcional y una de 5&#44; el menor deterioro funcional&#41;&#46; Del an&#225;lisis factorial se deducen 6 dominios diferentes que explora el cuestionario&#58; &#171;deseo&#187; &#40;&#237;tems 1&#44;2&#41;&#59; &#171;excitaci&#243;n&#187; &#40;&#237;tems 3&#44; 4&#44; 5&#44; 6&#41;&#59; &#171;lubricaci&#243;n&#187; &#40;&#237;tems 7&#44; 8&#44; 9&#44; 10&#41;&#59; &#171;orgasmo&#187; &#40;&#237;tems 11&#44; 12&#44; 13&#41;&#59; &#171;satisfacci&#243;n&#187; &#40;&#237;tems 14&#44; 15&#44; 16&#41;&#44; y &#171;dolor&#187; &#40;&#237;tems 17&#44; 18&#44; 19&#41;&#46; La calificaci&#243;n total del &#237;ndice de evaluaci&#243;n es la suma de todos los puntos obtenidos en cada dominio multiplicados por un factor&#44; con un m&#225;ximo de 36&#44; por lo que&#44; por debajo de 27 puntos&#44; se considera que existe alg&#250;n grado de disfunci&#243;n<a class="elsevierStyleCrossRef" href="#bib0225"><span class="elsevierStyleSup">19</span></a>&#46;</p><p id="par0060" class="elsevierStylePara elsevierViewall">En varones se utiliz&#243; el &#205;ndice Internacional de Funci&#243;n Er&#233;ctil &#40;<span class="elsevierStyleItalic">International Index of Erectile Function Questionnaire</span> &#91;IIEF&#93;&#41; en su versi&#243;n espa&#241;ola<a class="elsevierStyleCrossRefs" href="#bib0225"><span class="elsevierStyleSup">19&#44;20</span></a>&#46; Se trata de un instrumento breve&#44; sencillo y v&#225;lido para medir determinados aspectos relativos a la funci&#243;n sexual del var&#243;n&#46; Consta de 15 &#237;tems en los que se eval&#250;an distintos aspectos de la funci&#243;n sexual&#46; Para cada pregunta existen varias respuestas &#40;rango 0-5&#41;&#44; significando el 0 ausencia de actividad sexual o incapacidad para mantener una relaci&#243;n sexual&#46; Estos &#237;tems pueden ser agrupados en 5 dimensiones o dominios&#58; &#171;funci&#243;n er&#233;ctil&#187; &#40;cuestiones 1-5 y 15&#59; rango de puntuaci&#243;n 1-30&#41;&#59; &#171;funci&#243;n org&#225;smica&#187; &#40;cuestiones 9 y 10&#59; rango de puntuaci&#243;n 2-10&#41;&#59; &#171;deseo sexual&#187; &#40;cuestiones 11 y 12&#59; rango de puntuaci&#243;n 2-10&#41;&#59; &#171;satisfacci&#243;n en la relaci&#243;n sexual&#187; &#40;cuestiones 6-8&#59; rango de puntuaci&#243;n 0-15&#41; y &#171;satisfacci&#243;n global&#187; &#40;cuestiones 13 y 14&#59; rango de puntuaci&#243;n 2-10&#41;&#46; Adem&#225;s&#44; el cuestionario tiene una puntuaci&#243;n global que se obtiene sumando las obtenidas en todos sus &#237;tems&#44; con un rango de puntuaci&#243;n de entre 5 y 75&#44; consider&#225;ndose que con 60 o menos puntos existe alg&#250;n grado de disfunci&#243;n<a class="elsevierStyleCrossRef" href="#bib0225"><span class="elsevierStyleSup">19</span></a>&#46; El IIEF no solo permite la identificaci&#243;n de una posible DE&#44; sino tambi&#233;n estratificarla en varios grados de acuerdo con las puntuaciones obtenidas en el dominio &#171;funci&#243;n er&#233;ctil&#187;<a class="elsevierStyleCrossRef" href="#bib0235"><span class="elsevierStyleSup">21</span></a>&#58; ausencia de DE &#40;puntuaci&#243;n igual o superior a 26&#41;&#44; DE leve &#40;rango de puntuaci&#243;n 17-25&#41;&#44; DE moderada &#40;rango de puntuaci&#243;n 11-16&#41; y DE grave &#40;rango de puntuaci&#243;n 6-10&#41;&#46;</p></li><li class="elsevierStyleListItem" id="lsti0015"><span class="elsevierStyleLabel">c&#41;</span><p id="par0065" class="elsevierStylePara elsevierViewall">Espirometr&#237;a&#58; la espirometr&#237;a fue realizada de acuerdo con el procedimiento descrito previamente en la Normativa de espirometr&#237;a SEPAR<a class="elsevierStyleCrossRef" href="#bib0240"><span class="elsevierStyleSup">22</span></a>&#44; usando valores de referencia para poblaci&#243;n mediterr&#225;nea<a class="elsevierStyleCrossRef" href="#bib0245"><span class="elsevierStyleSup">23</span></a>&#46;</p></li></ul></p></span><span id="sec0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0080">An&#225;lisis estad&#237;stico</span><p id="par0070" class="elsevierStylePara elsevierViewall">Todos los an&#225;lisis se realizaron utilizando el paquete estad&#237;stico SPSS &#40;Chicago&#44; Illinois&#41;&#44; versi&#243;n 23&#46;0&#46; Se efectu&#243; un an&#225;lisis descriptivo para todas las variables recogidas de la muestra estudiada&#46; Los resultados se expresaron como porcentajes&#44; frecuencias y n&#250;mero de observaciones para las variables cualitativas y como medias con desviaci&#243;n est&#225;ndar para las cuantitativas&#46; Se calcularon las calificaciones generales y secundarias del estado de funci&#243;n sexual en pacientes y controles compar&#225;ndose las medias mediante la U de Mann-Whitney&#46; Las comparaciones entre grupos se realizaron mediante la prueba de la &#967;<span class="elsevierStyleSup">2</span> para las variables categ&#243;ricas y para las variables ordinales o cuantitativas&#44; con la prueba de Kruskall-Wallis&#44; tras comprobar que los valores no ten&#237;an una distribuci&#243;n normal&#46; Se comprobaron las correlaciones existentes entre la puntuaci&#243;n del cuestionario de funci&#243;n sexual con diferentes variables analizadas mediante el coeficiente de Pearson para las variables cuantitativas y de Spearman para las variables cualitativas&#46;</p><p id="par0075" class="elsevierStylePara elsevierViewall">Se realizaron an&#225;lisis bivariantes y multivariantes para valorar la asociaci&#243;n entre los diferentes factores&#46; Los modelos de regresi&#243;n se ajustaron con los factores que se asociaban a la variable dependiente en el an&#225;lisis bivariante &#40;p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;25&#41;&#46; Se calcularon las odds ratio &#40;OR&#41; y los intervalos de confianza &#40;IC&#41; para medir la asociaci&#243;n entre las variables&#46; Se incluy&#243; como variable dependiente la presencia&#47;ausencia de disfunci&#243;n sexual&#44; tanto en varones como en mujeres de forma independiente&#46; Con el objetivo de facilitar los an&#225;lisis se agruparon categor&#237;as &#40;IIEF mayor o menor de 60 y FSFI mayor o menor de 27&#41;&#46; En el caso del an&#225;lisis multivariado se evaluaron diferentes modelos y se seleccion&#243; el m&#225;s explicativo&#46; El m&#233;todo empleado fue la introducci&#243;n manual&#46; Se valor&#243; la bondad de ajuste mediante la prueba de Hosmer y Lemeshow&#46;</p></span></span><span id="sec0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0085">Resultados</span><p id="par0080" class="elsevierStylePara elsevierViewall">Se incluyeron un total de 276<span class="elsevierStyleHsp" style=""></span>casos&#44; de los que 172 eran asm&#225;ticos &#40;63 hombres y 109 mujeres&#41;&#46; Las caracter&#237;sticas demogr&#225;ficas de la muestra analizada y las caracter&#237;sticas cl&#237;nicas del grupo asma se recogen en las <a class="elsevierStyleCrossRefs" href="#tbl0005">tablas 1 y 2</a>&#46; Entre estos resultados destaca que el grupo de pacientes asm&#225;ticos mostraron un significativo mayor &#237;ndice de masa corporal &#40;IMC&#41; que el grupo control&#44; el porcentaje de fumadores activos fue similar y los <span class="elsevierStyleItalic">scores</span> de ansiedad y globales de GADS reflejaron una mayor puntuaci&#243;n en el grupo de asm&#225;ticos&#46; En cuanto a las caracter&#237;sticas del asma&#44; se observ&#243; una mayor proporci&#243;n de asma controlado en varones con respecto a mujeres&#46; El tratamiento para el asma m&#225;s frecuentemente documentado fue la asociaci&#243;n entre glucocorticoides inhalados y agonistas beta-2 adren&#233;rgicos de acci&#243;n larga &#40;LABA&#41; &#40;78&#44;6&#37;&#41;&#46; En cuanto a las comorbilidades descritas&#44; en el grupo de asm&#225;ticos destacaba la rinitis &#40;80&#44;8&#37;&#41;&#44; reflujo gastroesof&#225;gico &#40;20&#44;3&#37;&#41;&#44; ansiedad &#40;16&#44;8&#37;&#41;&#44; poliposis nasal &#40;14&#44;6&#37;&#41;&#44; depresi&#243;n &#40;11&#44;1&#37;&#41;&#44; hipertensi&#243;n arterial &#40;11&#37;&#41;&#44; diabetes &#40;4&#44;7&#37;&#41; y fibromialgia &#40;2&#44;9&#37;&#41;&#46; La preocupaci&#243;n por la sexualidad fue mostrada por el 47&#44;2&#37; del grupo de voluntarios sanos y en un 39&#44;9&#37; del grupo asm&#225;tico&#46; Las razones de esta preocupaci&#243;n se reflejan en la <a class="elsevierStyleCrossRef" href="#fig0005">figura 1</a>&#46; Pr&#225;cticamente una cuarta parte de los pacientes asm&#225;ticos relacionaban sus problemas sexuales con el hecho de padecer asma&#46;</p><elsevierMultimedia ident="tbl0005"></elsevierMultimedia><elsevierMultimedia ident="tbl0010"></elsevierMultimedia><elsevierMultimedia ident="fig0005"></elsevierMultimedia><p id="par0085" class="elsevierStylePara elsevierViewall">Las diferencias en la funci&#243;n sexual observadas entre asm&#225;ticos y controles quedan reflejadas en las <a class="elsevierStyleCrossRefs" href="#tbl0015">tablas 3 y 4</a>&#46; Se apreci&#243; una significativa disfunci&#243;n global&#44; tanto en la puntuaci&#243;n total como en las diferentes dimensiones del FSFI en mujeres asm&#225;ticas&#46; En varones se observ&#243; tambi&#233;n una significativa peor puntuaci&#243;n total del cuestionario IIEF&#44; siendo las dimensiones m&#225;s afectadas las del deseo y la satisfacci&#243;n global&#46; Aunque la puntuaci&#243;n en el &#237;tem de dificultades en la erecci&#243;n no mostr&#243; diferencias significativas entre el grupo de pacientes asm&#225;ticos versus el grupo control&#44; de acuerdo con la puntuaci&#243;n en funci&#243;n er&#233;ctil solo el 56&#37; de pacientes asm&#225;ticos carec&#237;an de problemas de impotencia frente al 74&#44;3&#37; del grupo control&#46; Entre los asm&#225;ticos&#44; el 36&#37; padec&#237;an una DE leve&#44; el 4&#37; moderada y otro 4&#37; grave&#46;</p><elsevierMultimedia ident="tbl0015"></elsevierMultimedia><elsevierMultimedia ident="tbl0020"></elsevierMultimedia><p id="par0090" class="elsevierStylePara elsevierViewall">En mujeres asm&#225;ticas se observaron correlaciones significativas entre la puntuaci&#243;n total del FSFI y las siguientes variables&#58; edad &#40;&#8211;0&#44;37&#59; p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&#41;&#44; IMC &#40;&#8211;0&#44;23&#59; p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;03&#41;&#44; tiempo de evoluci&#243;n de la enfermedad &#40;&#8211;0&#44;36&#59; p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&#41;&#44; FEV1&#37; &#40;0&#44;23&#59; p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;02&#41;&#44; gravedad y control de la enfermedad asm&#225;tica &#40;&#8211;0&#44;21 y &#8211;0&#44;27&#59; p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;05&#41; y aspectos emocionales&#44; como la existencia previa de depresi&#243;n o ansiedad &#40;&#8211;0&#44;32 y 0&#44;26&#59; p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;01&#41;&#44; puntuaci&#243;n alcanzada en el cuestionario de GADS &#40;&#8211;0&#44;32&#59; p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;001&#41; y existencia previa de hipertensi&#243;n arterial o diabetes &#40;&#8211;0&#44;33 y &#8211;0&#44;32&#59; p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;001&#41;&#46; Y en hombres&#44; entre la puntuaci&#243;n total del IIEF y las siguientes variables&#58; edad &#40;&#8211;0&#44;53&#59; p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;0001&#41;&#44; gravedad del asma &#40;&#8211;0&#44;41&#59; p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;001&#41;&#44; afectaci&#243;n de la funci&#243;n pulmonar &#40;0&#44;39&#59; p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;005&#41;&#44; tabaquismo &#40;&#8211;0&#44;38&#59; p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;003&#41;&#44; afectaci&#243;n de la v&#237;a a&#233;rea superior &#40;rinitis perenne&#59; &#8211;0&#44;28&#59; p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;04&#41;&#46; Tanto en un caso como en otro&#44; la existencia de diagn&#243;stico previo de asma de esfuerzo no pareci&#243; tener relaci&#243;n con una afectaci&#243;n de la vida sexual&#46;</p><p id="par0095" class="elsevierStylePara elsevierViewall">En las <a class="elsevierStyleCrossRefs" href="#tbl0025">tablas 5 y 6</a> se representan los resultados del an&#225;lisis bivariante y multivariante para la variable disfunci&#243;n&#47;no disfunci&#243;n&#44; en relaci&#243;n con los factores que podr&#237;an tener influencia en pacientes con asma&#44; de forma independiente en hombres y en mujeres&#46; En la <a class="elsevierStyleCrossRef" href="#tbl0025">tabla 5</a>b&#44; se representan los resultados obtenidos en hombres en el an&#225;lisis multivariante&#44; encontr&#225;ndose relaci&#243;n entre la presencia de disfunci&#243;n y la edad&#46; En el resto de variables no se observ&#243; asociaci&#243;n&#44; aunque se aproxim&#243; casi hasta el l&#237;mite de la significaci&#243;n &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;006&#41; con el grado de control de asma&#46; En el caso de las mujeres &#40;<a class="elsevierStyleCrossRef" href="#tbl0030">tabla 6</a>b&#41;&#44; se incluyeron en el modelo las variables que fueron significativas en el an&#225;lisis bivariante y la edad&#44; pero no se demostr&#243; asociaci&#243;n&#44; aunque se aproxim&#243; con el grado de control de la enfermedad&#46;</p><elsevierMultimedia ident="tbl0025"></elsevierMultimedia><elsevierMultimedia ident="tbl0030"></elsevierMultimedia></span><span id="sec0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0090">Discusi&#243;n</span><p id="par0100" class="elsevierStylePara elsevierViewall">La principal aportaci&#243;n del presente estudio es la constataci&#243;n de que los pacientes con asma pueden sufrir una disfunci&#243;n en la esfera sexual con mayor frecuencia que la poblaci&#243;n sana&#44; tanto en hombres como en mujeres&#46; Probablemente la falta de control de la enfermedad es uno de los factores que m&#225;s contribuyen a la existencia de esta disfunci&#243;n&#46;</p><p id="par0105" class="elsevierStylePara elsevierViewall">Existen trabajos previos que ponen de manifiesto&#44; en hombres&#44; asociaciones puntuales entre asma y DE<a class="elsevierStyleCrossRefs" href="#bib0195"><span class="elsevierStyleSup">13&#44;14</span></a>&#44; con la consiguiente repercusi&#243;n en las relaciones de pareja&#46; La DE puede definirse como la incapacidad persistente para lograr y mantener una erecci&#243;n adecuada que permita una actividad sexual satisfactoria&#46; Recientemente se ha publicado que el asma puede ser un factor de riesgo independiente para la aparici&#243;n de DE y esta asociaci&#243;n es m&#225;s estrecha cuanto mayor es la gravedad de la enfermedad bronquial<a class="elsevierStyleCrossRef" href="#bib0250"><span class="elsevierStyleSup">24</span></a>&#46; En nuestro estudio&#44; el dominio de la funci&#243;n er&#233;ctil no fue significativamente diferente entre asm&#225;ticos y voluntarios sanos&#44; aunque s&#237; exist&#237;a una disminuci&#243;n de otras facetas como el deseo sexual y la satisfacci&#243;n global en la relaci&#243;n en el grupo con enfermedad respiratoria&#46; No obstante&#44; objetivamos que la DE estaba presente en un 44&#37; de los asm&#225;ticos frente a solo un 25&#44;7&#37; en el grupo control&#44; que adem&#225;s era m&#225;s intensa en los pacientes&#46; As&#237; mismo&#44; se observ&#243; que la edad y la falta de control del asma se asociaron a una menor puntuaci&#243;n en las escalas de funci&#243;n sexual masculina en el an&#225;lisis multivariante&#46; Posiblemente&#44; el mayor control de la enfermedad asm&#225;tica observado en nuestros pacientes varones haya influido en cierta medida en la no afectaci&#243;n significativa observada en determinados &#237;tems de la encuesta de funci&#243;n sexual&#46;</p><p id="par0110" class="elsevierStylePara elsevierViewall">Nuestro estudio corrobora el hallazgo de algunos art&#237;culos recientes que enfatizan la importancia que tiene la enfermedad en esta esfera de la vida&#44; en particular en el sexo femenino&#46; En el estudio de Meyer et al&#46;<a class="elsevierStyleCrossRef" href="#bib0185"><span class="elsevierStyleSup">11</span></a>&#44; realizado en un servicio de urgencias de un hospital de New York&#44; los investigadores preguntaron a pacientes de la sala de urgencias sobre el grado en el que su asma hab&#237;a perjudicado la realizaci&#243;n de determinadas actividades&#46; De estas&#44; la limitaci&#243;n para la actividad sexual fue la tercera actividad que con mayor frecuencia identificaban las pacientes&#44; tras subir escaleras o realizar las tareas dom&#233;sticas habituales&#46; Dos terceras partes de los pacientes estudiados declararon experimentar limitaciones sexuales que se relacionaban con su asma&#46; Estas fueron m&#225;s prevalentes en aquellos pacientes que presentaban un asma moderada o grave en comparaci&#243;n con los de asma leve&#44; as&#237; como en los individuos de m&#225;s de 40 a&#241;os comparados con los menores de 40&#46; En cuanto al sexo&#44; la funci&#243;n sexual estuvo m&#225;s afectada en las mujeres asm&#225;ticas que acudieron a urgencias con respecto a los varones&#46;</p><p id="par0115" class="elsevierStylePara elsevierViewall">En un reciente estudio<a class="elsevierStyleCrossRef" href="#bib0190"><span class="elsevierStyleSup">12</span></a>&#44; realizado en 38 mujeres asm&#225;ticas casadas premenop&#225;usicas compar&#225;ndolas con 20 mujeres sanas&#44; se utiliz&#243; el FSFI&#44; para objetivar diferencias entre estos grupos en cuanto a posibles disfunciones&#46; Se observ&#243; disfunci&#243;n sexual en 18 de las pacientes con asma &#40;47&#44;4&#37;&#41;&#44; mientras que dicha alteraci&#243;n solo la presentaron 4 en el grupo control &#40;20&#37;&#41;&#46; El problema m&#225;s acusado en las asm&#225;ticas fue el referente a la excitaci&#243;n&#44; que estaba disminuida en 30 pacientes &#40;78&#44;9&#37;&#41;&#44; seguido de una disminuci&#243;n del deseo &#40;44&#44;7&#37;&#41;&#44; dolor durante el coito &#40;34&#44;2&#37;&#41; y dificultad para llegar al orgasmo &#40;31&#44;6&#37;&#41;&#46; Sin embargo&#44; las puntuaciones de satisfacci&#243;n fueron las menos afectadas y solo se encontraron por debajo de la normalidad en 5 &#40;13&#44;2&#37;&#41;&#46; Se observ&#243; tambi&#233;n la existencia de una fuerte correlaci&#243;n entre la puntuaci&#243;n del FSFI y las escalas utilizadas para utilizar el estatus psicol&#243;gico de las pacientes&#44; lo que sugiere que la disminuci&#243;n de la excitaci&#243;n y la libido observadas est&#225;n relacionadas con factores emocionales y psicol&#243;gicos&#46; Estos resultados son concordantes con los observados en nuestro estudio&#44; que en una muestra m&#225;s amplia se constat&#243; diferencias en todos los &#237;tems del FSFI&#44; excitaci&#243;n&#44; deseo&#44; orgasmo&#44; lubricaci&#243;n y satisfacci&#243;n&#44; y una relaci&#243;n inicial con factores emocionales&#44; tanto con la existencia de depresi&#243;n o ansiedad previamente diagnosticadas como con la puntuaci&#243;n alcanzada en los cuestionarios psicol&#243;gicos&#44; aunque posteriormente el an&#225;lisis multivariante no permiti&#243; determinar un modelo explicativo de la disfunci&#243;n en asm&#225;ticas&#46;</p><p id="par0120" class="elsevierStylePara elsevierViewall">Conviene destacar que una tercera parte de nuestros pacientes atribu&#237;an los problemas en la esfera de su vida sexual al padecimiento de su enfermedad asm&#225;tica&#44; existiendo una relaci&#243;n entre el tiempo de evoluci&#243;n de la misma y aspectos de gravedad&#44; control y deterioro de funci&#243;n pulmonar&#46; Encontramos una mayor preocupaci&#243;n sobre la sexualidad en el grupo control que en la poblaci&#243;n asm&#225;tica de nuestra serie&#44; y creemos que puede ser debido a que comparamos una poblaci&#243;n de enfermos con muchos s&#237;ntomas respiratorios no controlados&#44; que probablemente centrar&#237;an en muchas ocasiones sus temores&#44; en relaci&#243;n con una poblaci&#243;n sana sin comorbilidad y&#44; por tanto&#44; sin otros problemas que compitan con sus posibles afecciones en la esfera sexual&#46; Tenemos que se&#241;alar que un factor no considerado en nuestro estudio y que podr&#237;a tener influencia en este aspecto de la vida de nuestros pacientes puede ser la situaci&#243;n socioecon&#243;mica y&#47;o el nivel cultural de la poblaci&#243;n incluida&#44; que posiblemente deban ser tenidos en cuenta en futuras investigaciones que aborden el tema&#46;</p><p id="par0125" class="elsevierStylePara elsevierViewall">Es conocida la influencia en la sexualidad de la afectaci&#243;n de la v&#237;a a&#233;rea superior<a class="elsevierStyleCrossRefs" href="#bib0255"><span class="elsevierStyleSup">25&#44;26</span></a>&#44; tal y como recogen nuestros resultados&#44; en particular en varones &#40;gravedad de la rinitis&#41;&#46; Tambi&#233;n en este g&#233;nero&#44; el tabaquismo es otro factor concomitante a considerar y puede ser un factor limitante en nuestro estudio debido al mayor consumo de tabaco en nuestros pacientes asm&#225;ticos&#59; sin embargo&#44; el an&#225;lisis multivariante no lo incluy&#243; como factor predictor de posible disfunci&#243;n en nuestra serie&#46; Mientras&#44; en mujeres&#44; la existencia de enfermedades com&#243;rbidas como la hipertensi&#243;n arterial o la diabetes influenciaron en una menor puntuaci&#243;n en el cuestionario FSFI&#46; La hip&#243;tesis del denominado asma inducido por ejercicio sexual <span class="elsevierStyleItalic">&#40;sexercise induced asthma&#41;</span> no se demuestra en nuestra serie&#44; ya que no existe relaci&#243;n entre la funci&#243;n sexual de nuestros pacientes y el diagn&#243;stico previo de asma de esfuerzo&#46; Finalmente&#44; el an&#225;lisis multivariante de regresi&#243;n log&#237;stica parece orientar a que la falta de control de la enfermedad podr&#237;a ser un factor determinante en la disfunci&#243;n en esta esfera de la vida&#46;</p><p id="par0130" class="elsevierStylePara elsevierViewall">En resumen&#44; la sexualidad es un aspecto central de la calidad de vida del hombre y de la mujer y es el reflejo de su nivel de bienestar f&#237;sico&#44; psicol&#243;gico y social&#46; Sin embargo&#44; con frecuencia se elude afrontar este tema en la pr&#225;ctica m&#233;dica habitual&#46; El presente trabajo constata que tanto mujeres como hombres asm&#225;ticos presentan una disfunci&#243;n sexual significativa&#46; Esta afectaci&#243;n obedece a un origen multifactorial en el cual varios par&#225;metros parecen estar implicados&#44; como por ejemplo la gravedad de los s&#237;ntomas&#44; la existencia de comorbilidades propias del asma tales como afectaci&#243;n rin&#237;tica o disfunci&#243;n psicol&#243;gica&#46; Posiblemente&#44; un mejor control del asma deber&#237;a mejorar el funcionamiento sexual junto con otros aspectos de la vida del paciente&#46; Se precisan&#44; no obstante&#44; nuevos estudios que constaten dicho extremo&#44; as&#237; como elaborar recomendaciones espec&#237;ficas dirigidas a los pacientes con asma que incluyan aspectos relacionados con la sexualidad&#46;</p></span><span id="sec0035" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0095">Financiaci&#243;n</span><p id="par0135" class="elsevierStylePara elsevierViewall">El proyecto fue financiado mediante una subvenci&#243;n no restrictiva de Novartis Farmac&#233;utica&#44; S&#46;A&#46;&#44; Espa&#241;a&#46;</p></span><span id="sec0040" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0100">Conflicto de intereses</span><p id="par0140" class="elsevierStylePara elsevierViewall">J&#46; Gregorio Soto Campos declara haber recibido honorarios en &#250;ltimos dos a&#241;os por participar como ponente en Congresos y ayudas econ&#243;micas para asistir a eventos cient&#237;ficos por parte de Boehringer&#44; Novartis&#44; Chiesi&#44; Astra&#44; GSK y Vicente Plaza&#44; declara haber recibido en los tres &#250;ltimos a&#241;os honorarios por participar como orador en reuniones patrocinadas por Chiesi&#44; Esteve&#44; GSK&#44; Novartis&#44; Orion y Pfizer&#59; y como consultor de ALK&#44; MundiPharma&#44; Orion y Teva&#46; Recibi&#243; ayudas econ&#243;micas para la asistencia a congresos por parte de AZ&#44; Chiesi y Novartis&#46; Y recibi&#243; subvenciones para proyectos de investigaci&#243;n provenientes de AZ&#44; Chiesi y Menarini&#46;</p></span></span>"
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        "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Introducci&#243;n</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Las limitaciones de la vida sexual de los pacientes con enfermedades cr&#243;nicas desempe&#241;an un importante papel en su calidad de vida&#46; La informaci&#243;n disponible sobre el impacto de la enfermedad asm&#225;tica en la vida sexual de las personas es muy limitada&#46;</p></span> <span id="abst0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0015">Material y m&#233;todos</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Estudio transversal&#44; observacional y multic&#233;ntrico&#46; Se reclutaron pacientes asm&#225;ticos y sujetos sanos&#44; a los que se les efectu&#243; una entrevista en la que se recogieron datos demogr&#225;ficos y cl&#237;nicos y en donde adem&#225;s cumplimentaron los siguientes cuestionarios&#58; la escala <span class="elsevierStyleItalic">Goldberg</span> Anxiety<span class="elsevierStyleItalic">-Depression Scale</span> &#40;GADS&#41; para la valoraci&#243;n de la existencia de comorbilidad psiqui&#225;trica&#44; y en varones el &#205;ndice Internacional de la Funci&#243;n Er&#233;ctil &#40;IIEF&#41; y en mujeres el &#205;ndice de la Funci&#243;n Sexual Femenina &#40;FSFI&#41;&#46;</p></span> <span id="abst0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0020">Resultados</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Se incluyeron un total de 276<span class="elsevierStyleHsp" style=""></span>casos&#44; de los que 172 eran asm&#225;ticos &#40;63 hombres y 109 mujeres&#41; con una media de edad de 42 &#40;&#177;<span class="elsevierStyleHsp" style=""></span>14&#41; a&#241;os y 104 controles &#40;53 hombres y 51 mujeres&#41; con una media de edad de 39 &#40;&#177;<span class="elsevierStyleHsp" style=""></span>12&#41; a&#241;os&#46; El asma presentaba una evoluci&#243;n de 15<span class="elsevierStyleHsp" style=""></span>a&#241;os y su gravedad se distribu&#237;a&#58; 6&#44;4&#37; intermitente&#44; 17&#44;9&#37; persistente leve&#44; 47&#44;4&#37; moderada y 28&#44;2&#37; grave&#46; La enfermedad se consider&#243; controlada en un 57&#44;7&#37;&#44; parcialmente controlada en un 28&#44;2&#37; y no controlada en un 14&#44;1&#37;&#46; Las mujeres asm&#225;ticas presentaron una mayor limitaci&#243;n de la vida sexual que las mujeres del grupo control&#44; con una puntuaci&#243;n total del FSFI de 22&#44;1 &#40;&#177;<span class="elsevierStyleHsp" style=""></span>9&#41; frente a 26&#44;5 &#40;&#177;<span class="elsevierStyleHsp" style=""></span>6&#44;8&#41;&#44; respectivamente &#40;p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;005&#41;&#46; Y los varones asm&#225;ticos&#44; una significativa mayor disfunci&#243;n er&#233;ctil&#44; con una puntuaci&#243;n total del IIFE de 59&#44;5 &#40;&#177;<span class="elsevierStyleHsp" style=""></span>12&#44;5&#41; frente a 64&#44;3 &#40;&#177;<span class="elsevierStyleHsp" style=""></span>8&#44;2&#41;&#44; respectivamente &#40;p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;05&#41;&#46; Se observ&#243; adem&#225;s una relaci&#243;n entre la existencia de problemas sexuales y un peor control del asma&#46;</p></span> <span id="abst0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0025">Conclusiones</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">La enfermedad asm&#225;tica condiciona una peor calidad de vida sexual en las personas afectadas&#46; Estos resultados deber&#237;an promover&#44; en la pr&#225;ctica cl&#237;nica habitual&#44; el inter&#233;s de los profesionales sanitarios por determinar y paliar las posibles limitaciones sexuales de sus pacientes con asma&#46;</p></span>"
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        "resumen" => "<span id="abst0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0035">Introduction</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">Sexual limitations play an important role in the quality of life of patients with chronic diseases&#46; Very limited information is available on the impact of asthma on the sexual functioning of these individuals&#46;</p></span> <span id="abst0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0040">Materials and methods</span><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">Cross-sectional&#44; observational&#44; multicenter study&#46; Asthma patients and healthy individuals were recruited&#46; All subjects participated in an interview in which demographic and clinical data were recorded&#44; and completed the Goldberg Anxiety-Depression Scale &#40;GADS&#41; to evaluate the presence of concomitant psychiatric disease&#46; Men also completed the International Index of Erectile Function &#40;IIEF&#41;&#44; and women&#44; the Female Sexual Function Index &#40;FSFI&#41;&#46;</p></span> <span id="abst0035" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0045">Results</span><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">A total of 276<span class="elsevierStyleHsp" style=""></span>cases were included&#44; comprising 172<span class="elsevierStyleHsp" style=""></span>asthma patients &#40;63 men and 109 women&#41; with a mean age of 42 &#40;&#177;<span class="elsevierStyleHsp" style=""></span>14&#41; years&#44; and 104 controls &#40;52<span class="elsevierStyleHsp" style=""></span>men and 51<span class="elsevierStyleHsp" style=""></span>women&#41; with a mean age of 39 &#40;&#177;<span class="elsevierStyleHsp" style=""></span>12&#41; years&#46; Time since onset of asthma was 15 years and severity distribution was&#58; 6&#46;4&#37; intermittent&#44; 17&#46;9&#37; mild persistent&#44; 47&#46;4&#37; moderate&#44; and 28&#46;2&#37; severe&#46; Disease was considered controlled in 57&#46;7&#37;&#44; partially controlled in 28&#46;2&#37;&#44; and uncontrolled in 14&#46;1&#37;&#46; Women with asthma had greater sexual limitations than women in the control group&#44; with a total FSFI score of 22&#46;1 &#40;&#177;<span class="elsevierStyleHsp" style=""></span>9&#41; compared to 26&#46;5 &#40;&#177;<span class="elsevierStyleHsp" style=""></span>6&#46;8&#41;&#44; respectively &#40;<span class="elsevierStyleItalic">P</span><span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>&#46;005&#41;&#46; Men with asthma had significantly more severe erectile dysfunction with a total IIEF score of 59&#46;5 &#40;&#177;<span class="elsevierStyleHsp" style=""></span>12&#46;5&#41; compared to 64&#46;3 &#40;&#177;<span class="elsevierStyleHsp" style=""></span>8&#46;2&#41; in male controls &#40;<span class="elsevierStyleItalic">P</span><span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>&#46;05&#41;&#46; An association was also observed between sexual problems and poorer asthma control&#46;</p></span> <span id="abst0040" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0050">Conclusions</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">Asthma is associated with a poorer sexual quality of life among patients&#46; These results should arouse the interest of healthcare professionals in detecting and alleviating possible sexual limitations among their asthma patients in routine clinical practice&#46;</p></span>"
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          "leyenda" => "<p id="spar0055" class="elsevierStyleSimplePara elsevierViewall">Comparaci&#243;n entre grupos utilizando el test ANOVA o el Kruskall-Wallis si los valores no segu&#237;an una distribuci&#243;n normal&#46;</p><p id="spar0060" class="elsevierStyleSimplePara elsevierViewall">DE&#58; desviaci&#243;n est&#225;ndar&#59; GADS&#58; <span class="elsevierStyleItalic">Goldberg Anxiety-Depression Scale</span>&#59; IMC&#58; &#237;ndice de masa corporal&#59; IPA&#58; n&#46;<span class="elsevierStyleSup">o</span> de cigarrillos por d&#237;a<span class="elsevierStyleHsp" style=""></span>&#215;<span class="elsevierStyleHsp" style=""></span>a&#241;os fumando&#47;20&#46;</p>"
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                  \t\t\t\t\tvoid\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">19<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>15<a class="elsevierStyleCrossRef" href="#tblfn0005"><span class="elsevierStyleSup">a</span></a>&nbsp;\t\t\t\t\t\t\n
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          "leyenda" => "<p id="spar0070" class="elsevierStyleSimplePara elsevierViewall">Los valores se corresponden con la media &#40;desviaci&#243;n est&#225;ndar&#41; o n&#250;mero de casos &#40;porcentaje&#41;&#46;</p><p id="spar0075" class="elsevierStyleSimplePara elsevierViewall">Comparaciones entre grupos mediante ANOVA&#44; o Kruskall-Wallis si los valores no presentaban una distribuci&#243;n normal&#46;</p><p id="spar0080" class="elsevierStyleSimplePara elsevierViewall">DE&#58; desviaci&#243;n est&#225;ndar&#59; GINA&#58; Global Strategy for Asthma Management and Prevention&#59; NS&#58; no significativo&#46;</p><p id="spar0085" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleSup">&#42;</span> Comparaciones entre grupo asma &#40;hombres y mujeres&#41;&#46;</p>"
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                0 => """
                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Variable&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Mujeres &#40;n<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>109&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Todos &#40;n<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>172&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">p<span class="elsevierStyleSup">&#42;</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td" title="table-entry  " colspan="5" align="left" valign="top"><span class="elsevierStyleItalic">Ingresos por asma</span></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Pacientes ingresados&#44; n &#40;&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">13 &#40;11&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">6 &#40;7&#44;9&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">19 &#40;11&#44;8&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">NS&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Ingresos por pacientes&#44; media &#40;DE&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">1&#44;33<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>0&#44;65&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">1&#44;4<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>0&#44;89&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">1&#44;3<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>0&#44;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Visitas a urgencias &#40;a&#241;o anterior&#41;&#44; n &#40;&#37;&#41;</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">33 &#40;30&#44;8&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">17 &#40;27&#44;4&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">50 &#40;29&#44;6&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">NS&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Asma por ejercicio&#44; &#37;</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">19&#44;4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">28&#44;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">22&#44;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">NS&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">A&#241;os de evoluci&#243;n asma &#40;a&#241;os&#41;</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">16<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>11&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">15<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>11&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">15<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>11&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">NS&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="5" align="left" valign="top"><span class="elsevierStyleItalic">Control de asma &#40;GINA&#41;&#44; &#37;</span></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Controlado&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">45&#44;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">60&#44;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">51&#44;2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;026&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Parcialmente controlado&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">29&#44;2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">18&#44;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">25&#44;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>No controlado&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">25&#44;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">21&#44;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">23&#44;8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="5" align="left" valign="top"><span class="elsevierStyleItalic">Gravedad asma &#40;GINA&#41;&#44; &#37;</span></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Intermitente&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">8&#44;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">8&#44;2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">8&#44;9&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;053&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Persistente leve&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">11&#44;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">22&#44;9&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">15&#44;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Persistente moderado&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">43&#44;4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">44&#44;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">43&#44;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Persistente grave&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">36&#44;8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">24&#44;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">32&#44;1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="5" align="left" valign="top"><span class="elsevierStyleItalic">Espirometr&#237;a&#44; media &#40;DE</span>&#41;</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>FEV<span class="elsevierStyleInf">1</span>&#44; ml&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">2&#46;558<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>748&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">3&#46;504<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>1&#46;042&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">2&#46;925<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>991&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">NS&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>FEV<span class="elsevierStyleInf">1</span>&#44; &#37;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">89&#44;4<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>22&#44;4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">87<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>22&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">72&#44;6<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>12&#44;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">70&#44;8<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>12&#44;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">72<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>12&#44;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
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          "es" => "<p id="spar0065" class="elsevierStyleSimplePara elsevierViewall">Caracter&#237;sticas cl&#237;nicas de los pacientes con asma</p>"
        ]
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                  <table border="0" frame="\n
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                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Variable&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Grupo asma &#40;n<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>109&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;05&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;01&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Orgasmo&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">3&#44;99<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>1&#44;93&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">4&#44;67<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>1&#44;46&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;05&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Dolor&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">3&#44;63<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>1&#44;67&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">4&#44;16<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>1&#44;23&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;070&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Lubricaci&#243;n&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">4&#44;07<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>1&#44;89&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">4&#44;77<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>1&#44;41&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;05&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Satisfacci&#243;n&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">4&#44;25<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>0&#44;17&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">4&#44;85<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>0&#44;18&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;05&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
                  """
              ]
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                0 => "xTab1605807.png"
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        "descripcion" => array:1 [
          "es" => "<p id="spar0090" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleItalic">Female Sexual Function Index</span> &#40;FSFI&#41;&#44; puntuaci&#243;n observada en la poblaci&#243;n de mujeres estudiadas</p>"
        ]
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            0 => array:2 [
              "tabla" => array:1 [
                0 => """
                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Variable&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Puntuaci&#243;n total&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">64&#44;33<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>8&#44;28&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;05&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Funci&#243;n er&#233;ctil&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">25&#44;97<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>5&#44;82&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">27&#44;49<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>4&#44;05&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;123&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Deseo sexual&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">7&#44;38<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>0&#44;31&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;005&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Funci&#243;n org&#225;smica&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">8&#44;93<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>2&#44;13&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">9&#44;57<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>1&#44;11&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;085&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Satisfacci&#243;n con la relaci&#243;n&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">11&#44;20<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>3&#44;36&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">12&#44;15<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>1&#44;80&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;278&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Satisfacci&#243;n global&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">7&#44;32<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>2&#44;16&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">8&#44;02<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>2&#44;06&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;058&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
                  """
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          "es" => "<p id="spar0100" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleItalic">International Index of Erectile Function Questionnaire</span> &#40;IIEF&#41;&#44; puntuaci&#243;n observada en la poblaci&#243;n de varones estudiados</p>"
        ]
      ]
      5 => array:8 [
        "identificador" => "tbl0025"
        "etiqueta" => "Tabla 5"
        "tipo" => "MULTIMEDIATABLA"
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            "rol" => "short"
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        "tabla" => array:2 [
          "leyenda" => "<p id="spar0115" class="elsevierStyleSimplePara elsevierViewall">IIEF&#58; <span class="elsevierStyleItalic">International Index of Erectile Function Questionnaire</span>&#46;</p>"
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            0 => array:2 [
              "tabla" => array:1 [
                0 => """
                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="table-head  " colspan="5" align="center" valign="top" scope="col" style="border-bottom: 2px solid black">5a&#46; An&#225;lisis bivariante</th><th class="td" title="table-head  " colspan="4" align="center" valign="top" scope="col" style="border-bottom: 2px solid black">5b&#46; An&#225;lisis multivariante</th></tr><tr title="table-row"><th class="td-with-role" title="table-head ; entry_with_role_rowhead " align="left" valign="top" scope="col">Variables&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col">Variables&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col">p&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th></tr><tr title="table-row"><th class="td" title="table-head  " align="" valign="top" scope="col" style="border-bottom: 2px solid black">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">S&#237;<br>IIEF<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>60<br>&#40;n<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>24&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">No<br>IIEF<span class="elsevierStyleHsp" style=""></span>&#8805;<span class="elsevierStyleHsp" style=""></span>60<br>&#40;n<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>37&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Total &#40;n<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>63&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="" valign="top" scope="col" style="border-bottom: 2px solid black">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="" valign="top" scope="col" style="border-bottom: 2px solid black">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="" valign="top" scope="col" style="border-bottom: 2px solid black">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="" valign="top" scope="col" style="border-bottom: 2px solid black">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="" valign="top" scope="col" style="border-bottom: 2px solid black">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">H&#225;bito tab&#225;quico&#44; n &#40;&#37;&#41;</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top"><span class="elsevierStyleItalic">Edad</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;08&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">1&#44;08 &#40;1&#44;02-1&#44;15&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;005&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>No fuma&#47;exfumador&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">18 &#40;82&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">22 &#40;61&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">40&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;10&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Fumador&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">4 &#40;18&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">14 &#40;39&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">18&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Gravedad asma&#44; n &#40;&#37;&#41;</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top"><span class="elsevierStyleItalic">H&#225;bito tab&#225;quico</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">&#8211;0&#44;95&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;39 &#40;0&#44;08-1&#44;91&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;24&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Leve&#47;intermitente&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">3 &#40;14&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">11 &#40;34&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">14&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;09&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>No fuma&#44; exfumador&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Persistente-mod&#47;severo&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">18 &#40;86&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">21 &#40;65&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">39&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Fumador&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Grado de control asma&#44; n &#40;&#37;&#41;</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top"><span class="elsevierStyleItalic">Gravedad asma</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;63&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">1&#44;88 &#40;0&#44;35-10&#44;04&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;46&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Controlada&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">15 &#40;68&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">32 &#40;87&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">47&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;10&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Leve-intermitente&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>No controlada&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">7 &#40;32&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">5 &#40;13&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">12&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Persistente-mod&#47;severo&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Rinitis&#44; n &#40;&#37;&#41;</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top"><span class="elsevierStyleItalic">Grado de control asma</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">1&#44;64&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">5&#44;15 &#40;0&#44;91-29&#44;18&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;06&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>No&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">4 &#40;17&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">5 &#40;13&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">9&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;50&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Controlada&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>S&#237;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">20 &#40;83&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">32 &#40;86&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">52&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>No controlada&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Gravedad rinitis&#44; n &#40;&#37;&#41;</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Leve&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">7 &#40;37&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">17 &#40;53&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">24&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;38&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Moderada&#47;grave&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">12 &#40;63&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">15 &#40;47&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">27&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Ansiedad&#44; n &#40;&#37;&#41;</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>No&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">22 &#40;92&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">33 &#40;92&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">56&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;66&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>S&#237;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">2 &#40;8&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">3 &#40;8&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Depresi&#243;n&#44; n &#40;&#37;&#41;</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>No&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">23&#40;96&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">35 &#40;95&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">58&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>S&#237;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">2&#40;6&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">1 &#40;4&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
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          "es" => "<p id="spar0110" class="elsevierStyleSimplePara elsevierViewall">An&#225;lisis de la disfunci&#243;n sexual en el var&#243;n con asma</p>"
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                0 => """
                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="table-head  " align="" valign="top" scope="col">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " colspan="4" align="center" valign="top" scope="col" style="border-bottom: 2px solid black">6a&#46; An&#225;lisis bivariante</th><th class="td" title="table-head  " colspan="4" align="center" valign="top" scope="col" style="border-bottom: 2px solid black">6b&#46; An&#225;lisis multivariante</th></tr><tr title="table-row"><th class="td" title="table-head  " align="" valign="top" scope="col">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " colspan="3" align="center" valign="top" scope="col" style="border-bottom: 2px solid black">Disfunci&#243;n sexual</th><th class="td" title="table-head  " align="" valign="top" scope="col">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="" valign="top" scope="col">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="" valign="top" scope="col">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="" valign="top" scope="col">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="" valign="top" scope="col">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th></tr><tr title="table-row"><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Variables&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">S&#237;<br>FSFI<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>27<br>&#40;n<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>81&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">No<br>FSFI<span class="elsevierStyleHsp" style=""></span>&#8805;<span class="elsevierStyleHsp" style=""></span>27<br>&#40;n<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>23&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Total &#40;n<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>109&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">p&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Variables&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Coeficiente &#946;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">OR &#40;IC del 95&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">p&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">H&#225;bito tab&#225;quico&#44; n &#40;&#37;&#41;</span><br><span class="elsevierStyleHsp" style=""></span>No fuma&#47;exfumador<br><span class="elsevierStyleHsp" style=""></span>Fumador&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top"><br>68 &#40;86&#41;<br>11 &#40;14&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top"><br>15 &#40;71&#41;<br>6 &#40;29&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top"><br>83<br>17&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;11&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top"><span class="elsevierStyleItalic">Edad</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;024&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">1&#44;03 &#40;0&#44;99-1&#44;07&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;18&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Gravedad asma&#44; n &#40;&#37;&#41;</span><br><span class="elsevierStyleHsp" style=""></span>Leve-intermitente<br><span class="elsevierStyleHsp" style=""></span>Persistente-mod&#47;severo&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top"><br>9 &#40;12&#41;<br>66 &#40;88&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top"><br>2 &#40;11&#41;<br>16 &#40;89&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top"><br>11<br>82&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top"><span class="elsevierStyleItalic">H&#225;bito tab&#225;quico</span><br><span class="elsevierStyleHsp" style=""></span>No fuma&#47;exfumador<br><span class="elsevierStyleHsp" style=""></span>Fumador&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">&#8722;0&#44;65&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;52 &#40;0&#44;14-1&#44;90&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;32&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Grado de control asma&#44; n &#40;&#37;&#41;</span><br><span class="elsevierStyleHsp" style=""></span>Controlada<br><span class="elsevierStyleHsp" style=""></span>No controlada&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top"><br>55 &#40;69&#41;<br>25 &#40;31&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top"><br>20 &#40;91&#41;<br>2 &#40;9&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top"><br>75<br>27&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;03&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top"><span class="elsevierStyleItalic">Gravedad asma</span><br><span class="elsevierStyleHsp" style=""></span>Leve-intermitente<br><span class="elsevierStyleHsp" style=""></span>Persistente-mod&#47;severo&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">&#8211;0&#44;53&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;59 &#40;0&#44;11-3&#44;22&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;54&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Rinitis&#44; n &#40;&#37;&#41;</span><br><span class="elsevierStyleHsp" style=""></span>No<br><span class="elsevierStyleHsp" style=""></span>S&#237;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top"><br>17 &#40;21&#41;<br>63 &#40;78&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top"><br>6 &#40;27&#41;<br>16 &#40;73&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top"><br>23<br>80&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;57&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top"><span class="elsevierStyleItalic">Control asma</span><br><span class="elsevierStyleHsp" style=""></span>Controlada<br><span class="elsevierStyleHsp" style=""></span>No controlada&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">1&#44;35&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">3&#44;8 &#40;0&#44;82-18&#44;22&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;08&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Gravedad rinitis&#44; n &#40;&#37;&#41;</span><br><span class="elsevierStyleHsp" style=""></span>Leve<br><span class="elsevierStyleHsp" style=""></span>Moderada-grave&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top"><br>16 &#40;25&#41;<br>47 &#40;75&#41;<br>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top"><br>4 &#40;25&#41;<br>12 &#40;75&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top"><br>20<br>59&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Ansiedad&#44; n &#40;&#37;&#41;</span><br><span class="elsevierStyleHsp" style=""></span>No<br><span class="elsevierStyleHsp" style=""></span>S&#237;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top"><br>60 &#40;75&#41;<br>20 &#40;25&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top"><br>19 &#40;86&#41;<br>3 &#40;14&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top"><br>80<br>23&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;39&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Depresi&#243;n&#44; n &#40;&#37;&#41;</span><br><span class="elsevierStyleHsp" style=""></span>No<br><span class="elsevierStyleHsp" style=""></span>S&#237;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top"><br>65 &#40;81&#41;<br>15 &#40;19&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top"><br>21 &#40;95&#41;<br>1 &#40;5&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top"><br>86<br>16&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;18&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
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          "es" => "<p id="spar0120" class="elsevierStyleSimplePara elsevierViewall">An&#225;lisis de la disfunci&#243;n sexual en la mujer asm&#225;tica</p>"
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        0 => array:2 [
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            0 => array:3 [
              "identificador" => "bib0135"
              "etiqueta" => "1"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Sexual sequelae of general medical disorders"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "R&#46; Basson"
                            1 => "W&#46;W&#46; Schultz"
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                        ]
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                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/S0140-6736(07)60197-4"
                      "Revista" => array:6 [
                        "tituloSerie" => "Lancet&#46;"
                        "fecha" => "2007"
                        "volumen" => "369"
                        "paginaInicial" => "409"
                        "paginaFinal" => "424"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17276781"
                            "web" => "Medline"
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                      ]
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              "identificador" => "bib0140"
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                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Estudio piloto de la salud sexual en pacientes con enfermedad de M&#233;ni&#232;re"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "C&#46; Zapata"
                            1 => "J&#46;A&#46; L&#243;pez-Esc&#225;mez"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.otorri.2010.09.010"
                      "Revista" => array:6 [
                        "tituloSerie" => "Acta Otorrinolaringol Esp&#46;"
                        "fecha" => "2011"
                        "volumen" => "62"
                        "paginaInicial" => "119"
                        "paginaFinal" => "125"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/21112573"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
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                ]
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            2 => array:3 [
              "identificador" => "bib0145"
              "etiqueta" => "3"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Funci&#243;n sexual y calidad de vida en pacientes varones de hemodi&#225;lisis"
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                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "F&#46; Mart&#237;n-D&#237;az"
                            1 => "A&#46; Reig-Ferrer"
                            2 => "R&#46; Ferrer-Cascales"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Nefrolog&#237;a&#46;"
                        "fecha" => "2006"
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