Aspectos inmunologicos de los carcinomas broncopulmonares: Correlacion con el estadio tumoral, respuesta a la terapeutica y supervivencia
Inmunological aspects of bronchopulmonary carcinomas. Correlation with the tumor stage, response to therapy and survival rate
Read
3130
Timeswas read the article
1501
Total PDF
1629
Total HTML
Share statistics
array:22 [ "pii" => "S0300289615327368" "issn" => "03002896" "doi" => "10.1016/S0300-2896(15)32736-8" "estado" => "S300" "fechaPublicacion" => "1976-04-01" "aid" => "72805" "copyright" => "Sociedad Española de Neumología y Cirugía Torácica" "copyrightAnyo" => "1976" "documento" => "article" "crossmark" => 0 "subdocumento" => "fla" "cita" => "Arch Bronconeumol. 1976;12:53-7" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 1023 "formatos" => array:3 [ "EPUB" => 59 "HTML" => 499 "PDF" => 465 ] ] "itemSiguiente" => array:18 [ "pii" => "S030028961532737X" "issn" => "03002896" "doi" => "10.1016/S0300-2896(15)32737-X" "estado" => "S300" "fechaPublicacion" => "1976-04-01" "aid" => "72806" "copyright" => "Sociedad Española de Neumología y Cirugía Torácica" "documento" => "article" "crossmark" => 0 "subdocumento" => "fla" "cita" => "Arch Bronconeumol. 1976;12:58-62" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 1542 "formatos" => array:3 [ "EPUB" => 42 "HTML" => 829 "PDF" => 671 ] ] "es" => array:10 [ "idiomaDefecto" => true "titulo" => "Radiologia del empiema enquistado posterior en el hemitorax iz quierdo" "tienePdf" => "es" "tieneTextoCompleto" => 0 "tieneResumen" => array:2 [ 0 => "es" 1 => "en" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "58" "paginaFinal" => "62" ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Radiology of posterior encysted empyema" ] ] "contieneResumen" => array:2 [ "es" => true "en" => true ] "contienePdf" => array:1 [ "es" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "J.M. Rodríguez-Arias, J.C. Tarrés, I. Vidal-Quadras, M.<span class="elsevierStyleSup">a</span>C. Puzo, R. Cornudella" "autores" => array:5 [ 0 => array:2 [ "nombre" => "J.M." "apellidos" => "Rodríguez-Arias" ] 1 => array:2 [ "nombre" => "J.C." "apellidos" => "Tarrés" ] 2 => array:2 [ "nombre" => "I." "apellidos" => "Vidal-Quadras" ] 3 => array:2 [ "nombre" => "M.<span class="elsevierStyleSup">a</span>C." "apellidos" => "Puzo" ] 4 => array:2 [ "nombre" => "R." "apellidos" => "Cornudella" ] ] ] ] ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S030028961532737X?idApp=UINPBA00003Z" "url" => "/03002896/0000001200000002/v1_201509151250/S030028961532737X/v1_201509151250/es/main.assets" ] "es" => array:11 [ "idiomaDefecto" => true "titulo" => "Aspectos inmunologicos de los carcinomas broncopulmonares: Correlacion con el estadio tumoral, respuesta a la terapeutica y supervivencia" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "53" "paginaFinal" => "57" ] ] "autores" => array:1 [ 0 => array:3 [ "autoresLista" => "E. Simó-Camps, F. Manresa, A. Anguera, J.M.<span class="elsevierStyleSup">a</span> Vich, E. Batlló, G. Vidal, J.M.<span class="elsevierStyleSup">a</span> Puigdollers, G. Manresa-Formosa" "autores" => array:8 [ 0 => array:3 [ "nombre" => "E." "apellidos" => "Simó-Camps" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "aff0005" ] ] ] 1 => array:3 [ "nombre" => "F." "apellidos" => "Manresa" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">**</span>" "identificador" => "aff0010" ] ] ] 2 => array:3 [ "nombre" => "A." "apellidos" => "Anguera" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "aff0005" ] ] ] 3 => array:3 [ "nombre" => "J.M.<span class="elsevierStyleSup">a</span>" "apellidos" => "Vich" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "aff0005" ] ] ] 4 => array:3 [ "nombre" => "E." "apellidos" => "Batlló" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">***</span>" "identificador" => "aff0015" ] ] ] 5 => array:3 [ "nombre" => "G." "apellidos" => "Vidal" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">**</span>" "identificador" => "aff0010" ] ] ] 6 => array:3 [ "nombre" => "J.M.<span class="elsevierStyleSup">a</span>" "apellidos" => "Puigdollers" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">***</span>" "identificador" => "aff0015" ] ] ] 7 => array:3 [ "nombre" => "G." "apellidos" => "Manresa-Formosa" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">**</span>" "identificador" => "aff0010" ] ] ] ] "afiliaciones" => array:3 [ 0 => array:3 [ "entidad" => "Departamento de Inmunología y Quimioterapia Antitumoral. Universidad Autónoma de Barcelona. Hospital Sagrado Corazón" "etiqueta" => "*" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "Instituto de Neumología Clínica Ntra. Sra. de la Merced. Barcelona" "etiqueta" => "**" "identificador" => "aff0010" ] 2 => array:3 [ "entidad" => "Hospital del Sagrado Corazón. Barcelona" "etiqueta" => "***" "identificador" => "aff0015" ] ] ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Inmunological aspects of bronchopulmonary carcinomas. Correlation with the tumor stage, response to therapy and survival rate" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "tieneResumen" => true "resumen" => array:2 [ "es" => array:2 [ "titulo" => "Resumen" "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">La inmunidad celular fue estudiada en 79 pacientes afectos de carcinoma de pulmón, 50 testigos sanos y 14 tumoraciones benignas, observando si existía relación entre el estudio inmunológico de los pacientes y el estadio clínico de la enfermedad. La hipersensibilidad retardada fue correlacionada con el tipo histológico tumoral, el estadio de la enfermedad, la respuesta a la quimioterapia, el pronóstico y la supervivencia. Pacientes con anergia presentaban tumores muy diferenciados, falta de respuesta a la terapéutica, avanzada enfermedad y escasa supervivencia. En los pacientes con buena respuesta inmune, la enfermedad se hallaba limitada, respondían más frecuentemente a la terapéutica y presentaban una mayor supervivencia</p></span>" ] "en" => array:2 [ "titulo" => "Summary" "resumen" => "<span id="abst0010" class="elsevierStyleSection elsevierViewall"><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Cellular immunity was studied in 79 patients with carcinoma of the lung, 50 healthy individuals, and 14 cases with bening tumors, to see if there was any relationship between the immunological study of the patients and the clinical stage of the disease. The delayed hypersensitivity was related to the histological tumor type, the stage of the disease, response to chemotherapy, prognosis and survival rate. Anergic patients showed well differentiated tumors, lack of response to therapy, advanced disease, and low survival rate. In patients with good immune response the disease was limited, there was more frequent response to therapy and they displayed a higher survival rate.</p></span>" ] ] "bibliografia" => array:2 [ "titulo" => "Bibliografia" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:23 [ 0 => array:3 [ "identificador" => "bib0005" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Manifestations of immunologic unresponsivenes in Hodhkin's disease" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "A.C. Aisenberg" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Cancer Res." "fecha" => "1966" "volumen" => "26" "paginaInicial" => "1.152" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/5955599" "web" => "Medline" ] ] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib0010" "etiqueta" => "2." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Hodgkin's disease: Immunologic, clinical and histologic features of fifty untreated patients" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "R.S. Brown" 1 => "H.A. Haynes" 2 => "T. Foley" 3 => "H.A. Godwin" 4 => "C.W. Bernard" 5 => "P.P. Carbone" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Ann. Intern. Med." "fecha" => "1967" "volumen" => "67" "paginaInicial" => "291" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/6036391" "web" => "Medline" ] ] ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib0015" "etiqueta" => "3." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Immunologic deficiency disorders associated with chronic lymphocyte leukemia and múltiple myeloma" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "L. Cone" 1 => "J.W. Uhr" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1172/JCI105078" "Revista" => array:5 [ "tituloSerie" => "J Clin. Invest." "fecha" => "1964" "volumen" => "43" "paginaInicial" => "2.241" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/14228539" "web" => "Medline" ] ] ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib0020" "etiqueta" => "4." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Patient survival after chemotherapy and its relationship to in vitro lymphocyte blastogenesis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "A.R. Cheema" 1 => "E.M. Hers" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Cancer" "fecha" => "1971" "volumen" => "28" "paginaInicial" => "851" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/5286447" "web" => "Medline" ] ] ] ] ] ] ] ] 4 => array:3 [ "identificador" => "bib0025" "etiqueta" => "5." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Impaired immunologic reactivity and recurrence following cancer surgery" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "F.R. Eilber" 1 => "D.L. Morton" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Cancer" "fecha" => "1970" "volumen" => "25" "paginaInicial" => "362" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/5413507" "web" => "Medline" ] ] ] ] ] ] ] ] 5 => array:3 [ "identificador" => "bib0030" "etiqueta" => "6." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Immunologic alterations in bronchogenic cancer" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "M.J. Krant" 1 => "G. Manskopf" 2 => "C.S. Branddrup" 3 => "M.A. Madoff" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Cancer" "fecha" => "1968" "volumen" => "21" "paginaInicial" => "623" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/5643759" "web" => "Medline" ] ] ] ] ] ] ] ] 6 => array:3 [ "identificador" => "bib0035" "etiqueta" => "7." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Contribution a l’etude des phenomenes d’immunité cellulaire chez les cancereux pulmonaires. Avant traiæment palliacif ou chirurgical" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "L. Israel" 1 => "A. Bouvrain" 2 => "J. Crosdecam" 3 => "J. Mugica" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:4 [ "tituloSerie" => "Poumon et Coeur" "fecha" => "1968" "volumen" => "24" "paginaInicial" => "339" ] ] ] ] ] ] 7 => array:3 [ "identificador" => "bib0040" "etiqueta" => "8." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Lymphocyte response to PHA in patiens with lung cancer" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "J. Ducos" 1 => "J. Migueres" 2 => "P. Colombies" 3 => "A. Kessous" 4 => "N. Poujoulet" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/S2352-3018(14)70027-X" "Revista" => array:5 [ "tituloSerie" => "Lancet" "fecha" => "1970" "volumen" => "1" "paginaInicial" => "1.111" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/26366430" "web" => "Medline" ] ] ] ] ] ] ] ] 8 => array:3 [ "identificador" => "bib0045" "etiqueta" => "9." "referencia" => array:1 [ 0 => array:1 [ "referenciaCompleta" => "Brugarolas, A. y Takita, H.: Skin test in the stating of carcinoma of the lung. <span class="elsevierStyleItalic">Clin. Res</span>., 19: 737, 1071" ] ] ] 9 => array:3 [ "identificador" => "bib0050" "etiqueta" => "10." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Immunologic impairment in bronchogenic carcinoma: a study of lymphocytes response to phytohemagglutinin" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "T. Han" 1 => "H. Takita" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Cancer" "fecha" => "1972" "volumen" => "30" "paginaInicial" => "616" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/4342406" "web" => "Medline" ] ] ] ] ] ] ] ] 10 => array:3 [ "identificador" => "bib0055" "etiqueta" => "11." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Immunologic status in lung cancer" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "A. Brugarolas" 1 => "H. Takita" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Chest" "fecha" => "1973" "volumen" => "64" "paginaInicial" => "427" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/4355273" "web" => "Medline" ] ] ] ] ] ] ] ] 11 => array:3 [ "identificador" => "bib0060" "etiqueta" => "12." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Delayed cutaneous hypersensitivity reactins to tumot cell antigens and to nonspecific antigens. Prognostic significance in patiens with lung cancer" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "S.A. Wells" 1 => "J.F. Burdick" 2 => "W.L. Joseph" 3 => "C.L. Christiansen" 4 => "W.G. Wolfe" 5 => "P.C. Adkins" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "J. Thorac. Cardiovasc. Surg." "fecha" => "1973" "volumen" => "66" "paginaInicial" => "557" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/4755446" "web" => "Medline" ] ] ] ] ] ] ] ] 12 => array:3 [ "identificador" => "bib0065" "etiqueta" => "13." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "A method for D.N.C.B. contad sensitization: A clinicopathologic study" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "W.J. Catalona" 1 => "P.T. Taylor" 2 => "A.S. Rabson" 3 => "P.B. Chretien" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1056/NEJM197202242860804" "Revista" => array:5 [ "tituloSerie" => "New. Engl. J. Med." "fecha" => "1972" "volumen" => "286" "paginaInicial" => "399" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/5009231" "web" => "Medline" ] ] ] ] ] ] ] ] 13 => array:3 [ "identificador" => "bib0070" "etiqueta" => "14." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Indice de transformación blastica de los linfocitos en las farmacodermias" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "J.M. Moragas" 1 => "A. Anguera" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:4 [ "tituloSerie" => "Rev. Clin. Esp." "fecha" => "1972" "volumen" => "124" "paginaInicial" => "3" ] ] ] ] ] ] 14 => array:3 [ "identificador" => "bib0075" "etiqueta" => "15." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Human lymphocyte migration as a parameter of hypersensitivity" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "M. Soborg" 1 => "G. Bendixen" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:4 [ "tituloSerie" => "Acta Med., Scand." "fecha" => "1967" "volumen" => "181" "paginaInicial" => "247" ] ] ] ] ] ] 15 => array:3 [ "identificador" => "bib0080" "etiqueta" => "16." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Immunochemical quan-titation of antigens by single radial inmunodiffusion" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "G. Mancini" 1 => "A.D. Carbonova" 2 => "J.F. Heremans" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Immunochemistry." "fecha" => "1965" "volumen" => "2" "paginaInicial" => "235" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/4956917" "web" => "Medline" ] ] ] ] ] ] ] ] 16 => array:3 [ "identificador" => "bib0085" "etiqueta" => "17." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Prognestic implications of presurgical stating in lung cancer" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "C. Mountain" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "LibroEditado" => array:4 [ "titulo" => "cancer Medicine (Holland)" "paginaInicial" => "1.491" "paginaFinal" => "1.492" "serieFecha" => "1975" ] ] ] ] ] ] 17 => array:3 [ "identificador" => "bib0090" "etiqueta" => "18." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Immunological aspects of neoplasia: A rational basis for immunotherapy" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "D.L. Morton" 1 => "E.C. Holmes" 2 => "R.F. Eilber" 3 => "W.C. Wood" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Ann. Intern. Med." "fecha" => "1971" "volumen" => "74" "paginaInicial" => "587" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/4927902" "web" => "Medline" ] ] ] ] ] ] ] ] 18 => array:3 [ "identificador" => "bib0095" "etiqueta" => "19." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The delayed hypersensitivity reaction in the cancer patients: Observations on sensitization by D.N" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "R.C. Chakravotty" 1 => "P. Curutchet" 2 => "F.S. Copolla" 3 => "Ch.M. Park" 4 => "K. Blayloch" 5 => "W. Lawrence Jr." ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:4 [ "tituloSerie" => "C.B. Sugery" "fecha" => "1973" "volumen" => "73" "paginaInicial" => "730" ] ] ] ] ] ] 19 => array:3 [ "identificador" => "bib0100" "etiqueta" => "20." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Abnormalities of quantitative Dinitrochlorobenzene sensitization in cancer patients: Correlation with tumor stage and histology" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "W.j Catalona" 1 => "P.B. Chretien" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Cancer" "fecha" => "1973" "volumen" => "31" "paginaInicial" => "353" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/4687881" "web" => "Medline" ] ] ] ] ] ] ] ] 20 => array:3 [ "identificador" => "bib0105" "etiqueta" => "21." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Impaired In Vitro lymphocyte transformation in Hodgkin's disease" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "E.M. Hers" 1 => "J.J. Oppenheim" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1056/NEJM196512162732501" "Revista" => array:5 [ "tituloSerie" => "New. Engl. J. Med." "fecha" => "1965" "volumen" => "273" "paginaInicial" => "1.003," "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/5848113" "web" => "Medline" ] ] ] ] ] ] ] ] 21 => array:3 [ "identificador" => "bib0110" "etiqueta" => "22." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Delayed hypersensitivity in cancer patients. Cutaneous and in vitro lymphocyte response to specific antigens" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "H.S. Nelson" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:4 [ "tituloSerie" => "Natl. Cancer Inst." "fecha" => "1969" "volumen" => "42" "paginaInicial" => "765" ] ] ] ] ] ] 22 => array:3 [ "identificador" => "bib0115" "etiqueta" => "23." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Cellular immunty in cured cáncer patients" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "P.L. Twomey" 1 => "W.J. Catalona" 2 => "P.B. Chretien" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Cancer" "fecha" => "1974" "volumen" => "33" "paginaInicial" => "435" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/4812762" "web" => "Medline" ] ] ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "es" "url" => "/03002896/0000001200000002/v1_201509151250/S0300289615327368/v1_201509151250/es/main.assets" "Apartado" => array:4 [ "identificador" => "9277" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Originales" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/03002896/0000001200000002/v1_201509151250/S0300289615327368/v1_201509151250/es/main.pdf?idApp=UINPBA00003Z&text.app=https://archbronconeumol.org/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289615327368?idApp=UINPBA00003Z" ]
| Year/Month | Html | Total | |
|---|---|---|---|
| 2024 November | 3 | 4 | 7 |
| 2024 October | 25 | 14 | 39 |
| 2024 September | 31 | 14 | 45 |
| 2024 August | 41 | 24 | 65 |
| 2024 July | 29 | 24 | 53 |
| 2024 June | 43 | 20 | 63 |
| 2024 May | 39 | 32 | 71 |
| 2024 April | 29 | 19 | 48 |
| 2024 March | 31 | 19 | 50 |
| 2024 February | 28 | 33 | 61 |
| 2023 December | 0 | 6 | 6 |
| 2023 November | 0 | 4 | 4 |
| 2023 October | 0 | 4 | 4 |
| 2023 September | 0 | 1 | 1 |
| 2023 August | 0 | 4 | 4 |
| 2023 July | 0 | 14 | 14 |
| 2023 March | 9 | 4 | 13 |
| 2023 February | 29 | 15 | 44 |
| 2023 January | 21 | 24 | 45 |
| 2022 December | 29 | 26 | 55 |
| 2022 November | 27 | 17 | 44 |
| 2022 October | 28 | 33 | 61 |
| 2022 September | 26 | 16 | 42 |
| 2022 August | 27 | 37 | 64 |
| 2022 July | 27 | 34 | 61 |
| 2022 June | 27 | 35 | 62 |
| 2022 May | 18 | 28 | 46 |
| 2022 April | 32 | 33 | 65 |
| 2022 March | 37 | 36 | 73 |
| 2022 February | 29 | 25 | 54 |
| 2022 January | 22 | 25 | 47 |
| 2021 December | 14 | 43 | 57 |
| 2021 November | 19 | 23 | 42 |
| 2021 October | 17 | 33 | 50 |
| 2021 September | 25 | 36 | 61 |
| 2021 August | 20 | 27 | 47 |
| 2021 July | 41 | 14 | 55 |
| 2021 June | 20 | 30 | 50 |
| 2021 May | 19 | 18 | 37 |
| 2021 April | 14 | 29 | 43 |
| 2021 March | 30 | 19 | 49 |
| 2021 February | 34 | 7 | 41 |
| 2021 January | 23 | 16 | 39 |
| 2020 December | 22 | 5 | 27 |
| 2020 November | 10 | 11 | 21 |
| 2020 October | 18 | 7 | 25 |
| 2020 September | 10 | 9 | 19 |
| 2020 August | 24 | 13 | 37 |
| 2020 July | 15 | 13 | 28 |
| 2020 June | 10 | 11 | 21 |
| 2020 May | 15 | 16 | 31 |
| 2020 April | 21 | 7 | 28 |
| 2020 March | 10 | 19 | 29 |
| 2020 February | 19 | 18 | 37 |
| 2020 January | 24 | 23 | 47 |
| 2019 December | 22 | 27 | 49 |
| 2019 November | 7 | 8 | 15 |
| 2019 October | 11 | 6 | 17 |
| 2019 September | 5 | 19 | 24 |
| 2019 August | 8 | 8 | 16 |
| 2019 July | 13 | 19 | 32 |
| 2019 June | 14 | 19 | 33 |
| 2019 May | 8 | 19 | 27 |
| 2019 April | 11 | 24 | 35 |
| 2019 March | 0 | 17 | 17 |
| 2019 February | 3 | 4 | 7 |
| 2019 January | 7 | 7 | 14 |
| 2018 December | 3 | 11 | 14 |
| 2018 November | 7 | 8 | 15 |
| 2018 October | 16 | 13 | 29 |
| 2018 September | 3 | 3 | 6 |
| 2018 May | 5 | 1 | 6 |
| 2018 April | 5 | 4 | 9 |
| 2018 March | 10 | 7 | 17 |
| 2018 February | 8 | 16 | 24 |
| 2018 January | 6 | 5 | 11 |
| 2017 December | 8 | 8 | 16 |
| 2017 November | 9 | 11 | 20 |
| 2017 October | 8 | 5 | 13 |
| 2017 September | 6 | 7 | 13 |
| 2017 August | 14 | 13 | 27 |
| 2017 July | 7 | 5 | 12 |
| 2017 June | 8 | 16 | 24 |
| 2017 May | 13 | 10 | 23 |
| 2017 April | 7 | 4 | 11 |
| 2017 March | 5 | 13 | 18 |
| 2017 February | 4 | 2 | 6 |
| 2017 January | 2 | 5 | 7 |
| 2016 December | 7 | 2 | 9 |
| 2016 November | 17 | 12 | 29 |
| 2016 October | 17 | 20 | 37 |
| 2016 September | 16 | 10 | 26 |
| 2016 August | 16 | 5 | 21 |
| 2016 July | 22 | 5 | 27 |
| 2016 June | 21 | 8 | 29 |
| 2016 May | 14 | 3 | 17 |
| 2016 April | 9 | 0 | 9 |
| 2016 March | 9 | 0 | 9 |
| 2016 February | 5 | 0 | 5 |
| 2016 January | 10 | 4 | 14 |
| 2015 December | 20 | 11 | 31 |
| 2015 November | 18 | 5 | 23 |
| 2015 October | 4 | 1 | 5 |
Show all
