Transporte de oxigeno
Transportation of oxygen
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A proposito de seis observaciones" "tienePdf" => "es" "tieneTextoCompleto" => 0 "tieneResumen" => array:2 [ 0 => "es" 1 => "en" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "184" "paginaFinal" => "186" ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Endobronchial metastasis: based on six observations" ] ] "contieneResumen" => array:2 [ "es" => true "en" => true ] "contienePdf" => array:1 [ "es" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "F. de la Calle del Moral, A. Ladaria Ferrer, E. López-Bermejo Muñoz, M. Ull Laita, V. Moggi Zafferani, J.A. Ballesteros Fernández" "autores" => array:6 [ 0 => array:2 [ "nombre" => "F." "apellidos" => "de la Calle del Moral" ] 1 => array:2 [ "nombre" => "A." "apellidos" => "Ladaria Ferrer" ] 2 => array:2 [ "nombre" => "E." "apellidos" => "López-Bermejo Muñoz" ] 3 => array:2 [ "nombre" => "M." "apellidos" => "Ull Laita" ] 4 => array:2 [ "nombre" => "V." "apellidos" => "Moggi Zafferani" ] 5 => array:2 [ "nombre" => "J.A." "apellidos" => "Ballesteros Fernández" ] ] ] ] ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S030028961532531X?idApp=UINPBA00003Z" "url" => "/03002896/0000001500000004/v1_201509151302/S030028961532531X/v1_201509151302/es/main.assets" ] "es" => array:12 [ "idiomaDefecto" => true "titulo" => "Transporte de oxigeno" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "187" "paginaFinal" => "195" ] ] "autores" => array:1 [ 0 => array:3 [ "autoresLista" => "María Teresa García Carmona" "autores" => array:1 [ 0 => array:3 [ "nombre" => "María Teresa" "apellidos" => "García Carmona" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "aff0005" ] ] ] ] "afiliaciones" => array:1 [ 0 => array:3 [ "entidad" => "Jefe Adjunto del Servicio de Funciones Respiratorias. Clínica Puerta de Hierro. Centro Nacional de Investigaciones medico-quirúrgicas de La Seguridad Social. Madrid" "etiqueta" => "*" "identificador" => "aff0005" ] ] ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Transportation of oxygen" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "1979-01-23" "tieneResumen" => true "resumen" => array:2 [ "es" => array:2 [ "titulo" => "Resumen" "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Se hace una revisión general den transporte de oxígeno orientado principalmente el análisis de los aspectos bioquímicos implicados en él, comenzando por estudiar el papel de la hemoglobina como transportadora de oxígeno, tanto en lo que se refiere a su concentración como a su afinidad por el oxígeno.</p><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Se estudia el significado de la máxima capacidad de oxigenación destacando la importancia que puede tener la presencia de caboxihemoglobina en la sangre, ya que ésta disminuye el valor teórico de la mencionada máxima capacidad de oxigenación. Se propone una corrección para el cálculo en el laboratorio del oxígeno que transporta una sangre, teniendo en cuenta la concentración de carboxihemoglobina, siempre que se trate de personas fumadoras o se presuma que existan concentraciones elevadas de la misma.</p><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">A continuación se hace un estudio profundo de la afinidad de la hemoglobina por el oxígeno a través de la curva de disociación, comenzando por definir la P<span class="elsevierStyleInf">50</span> y discutiendo el significado fisiológico de los desplazamientos de dicha curva como consecuencia de los cambios de afinidad. Se describen en detalle la estructura de la molécula de hemoglobina, así como los fenómenos que se producen durante la oxigenación y desoxigenación del tetrámero de hemoglobina. Se incluyen también los mecanismos de regulación de la afinidad de la hemoglobina por el oxígeno, resaltando la importancia de los hidro-geniones, PCO<span class="elsevierStyleInf">2</span> y concentración de 2,3 DPG en esta regulación, siendo los aumentos de acidez y PCO<span class="elsevierStyleInf">2</span> mecanismos de acción rápida, mientras que los de 2,3 DPG tardan algunas horas en producirse.</p><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">Se exponen brevemente los métodos de medida y se analizan las modificaciones de la afinidad de la hemoglobina por el oxígeno en diversas situaciones fisiológicas y patológicas.</p><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">Se describen los mecanismos de consumo de oxígeno a nivel celular, la formación de ATP y la utilización de la energía almacenada en esta molécula por el organismo. Por último, se expone la producción de ATP en casos de anaerobiosis por medio de la glucólisis anaerobia, destacando que es necesaria la producción de una considerable cantidad de ácido láctico para satisfacer las necesidades energéticas por esta vía. Se mencionan las limitaciones que supone el empleo del aumento de la relación L/P y el exceso de lactato para diagnosticar las hipoxias celulares.</p></span>" ] "en" => array:2 [ "titulo" => "Summary" "resumen" => "<span id="abst0010" class="elsevierStyleSection elsevierViewall"><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">The authors make a general review of the transportation of oxygen oriented principally towards the analysis of the biochemical aspect implied in this process. They begin by studying the role of hemoglobin as transportation agent of oxygen, both with respect to ist concentration as wel as to its affinity for oxygen.</p><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">They also study the meaning of the maximum capacity of oxygenation, emphasizing the importance that carboxyhemoglobin in the blood can have, as this decreases the theoretical value of the mentioned maximum capacity of oxygenation. They propose a correction for the calculation in the laboratory of the oxygen transported by the blood taking into account the concentration of carboxyhemoglogin, always when the persons treated are smokers or they presume an elevated concentration of the same.</p><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">The authors then make a profound study of the affinity of hemoglobin for oxygen through the curve of dissociation, beginning by defining P<span class="elsevierStyleInf">30</span> and discussing the physiological meaning of the displacement of said curve as a consequence of the changes of affinity. They describe in detail the structure of the molecule of hemoglobin as well as the phenomena produced during the oxygenation and desoxygenation of the tetramer of hemoglobin. They also include the mechanisms of regulation fo affinity of hemoglobin for oxygen, emphasizing the importance of hydrogen ions, PCO<span class="elsevierStyleInf">2</span> and concentration of 2,3 DPG in this regulation. The increases of acidity and of PCO<span class="elsevierStyleInf">2</span> are mechanisms of rapid action, whereas those of 2,3 DPG delay some hours in being produced.</p><p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">The authors then describe birefly the methods of measurement and analyze the modifications of the affinity of hemoglobin for oxygen in diverse physiological and pathological situations.</p><p id="spar0050" class="elsevierStyleSimplePara elsevierViewall">They also describe the mechanisms of concumption of oxygen at the cellular level, the formation of ATP and the use of energy stored in this molecule by the organism. Finally, they discuss the production of ATP in cases of anaerobiosis by means of glycolysisanaerobia, emphasizing that the production of a considerable quantity of lactic acid is necessary to satisfy energetic necessities by this route. They mention the limitations that the use of the increase of the relation L/P supposes and the excess of láclate for diagnozing cellular hypoxias.</p></span>" ] ] "bibliografia" => array:2 [ "titulo" => "Bibliografia" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:70 [ 0 => array:3 [ "identificador" => "bib0005" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Affinité de l’hemoglobine pour l’oxygene" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "M. Robert" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:4 [ "tituloSerie" => "Bull. europ. Physiopath., resp." "fecha" => "1975" "volumen" => "11" "paginaInicial" => "79" ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib0010" "etiqueta" => "2." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Regulation of cardiac output" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "A.C. Guyton" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:4 [ "tituloSerie" => "Anaesthesiology" "fecha" => "1968" "volumen" => "29" "paginaInicial" => "314" ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib0015" "etiqueta" => "3." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Contribution of small vessel tone to the regulation of blood volumen and formation of oedema" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "S. Mellander" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Proc. R. Soc. Med." "fecha" => "1968" "volumen" => "61" "paginaInicial" => "55" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/5636288" "web" => "Medline" ] ] ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib0020" "etiqueta" => "4." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "ABC de l’equilibre biochimique acido-basique" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "H.W. Davenport" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Libro" => array:3 [ "fecha" => "1970" "editorial" => "Masson et Cie" "editorialLocalizacion" => "Paris" ] ] ] ] ] ] 4 => array:3 [ "identificador" => "bib0025" "etiqueta" => "5." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The influence of carboxihemoglobin on the oxygen-binding capacity of blood" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "E. Dominguez de Villota" 1 => "T. Garcia Carmona" 2 => "G. Barat" 3 => "J. Estada" 4 => "F. Avello" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:4 [ "tituloSerie" => "Br. J. Anaest." "fecha" => "1976" "volumen" => "48" "paginaInicial" => "111" ] ] ] ] ] ] 5 => array:3 [ "identificador" => "bib0030" "etiqueta" => "6." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Comparison of oxygen content of blood measured directly with values derived from measurements of oxygen tension" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "P. Foex" 1 => "C. Prys Roberts" 2 => "C.E. Hahn" 3 => "M. Fenton" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Br. J. Anaesth." "fecha" => "1970" "volumen" => "42" "paginaInicial" => "803" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/5470074" "web" => "Medline" ] ] ] ] ] ] ] ] 6 => array:3 [ "identificador" => "bib0035" "etiqueta" => "7." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Neue Versuche zur Bestimmung der Sauerstoff Capacitat des Blutfarbstffs" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "G. Hufner" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:3 [ "tituloSerie" => "Arch. Anat. Physiol., (Physiol.)" "fecha" => "1894" "paginaInicial" => "130" ] ] ] ] ] ] 7 => array:3 [ "identificador" => "bib0040" "etiqueta" => "8." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The oxygen combining capacity of hemoglobin" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "M. Scherrer" 1 => "H. Bachofen" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:4 [ "tituloSerie" => "Anaesthesiology" "fecha" => "1972" "volumen" => "36" "paginaInicial" => "190" ] ] ] ] ] ] 8 => array:3 [ "identificador" => "bib0045" "etiqueta" => "9." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The cardiorespiratory effects of haemorhage and overtransfusion in does" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "M.K. Sykes" 1 => "A.P. Adams" 2 => "W.E. Finlay" 3 => "A.E. Wightman" 4 => "J.D. Monroe" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Br. J. Anaesth." "fecha" => "1970" "volumen" => "42" "paginaInicial" => "573" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/5453240" "web" => "Medline" ] ] ] ] ] ] ] ] 9 => array:3 [ "identificador" => "bib0050" "etiqueta" => "10." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Calculation of blood O2 content from optically determined Hb and HbO<span class="elsevierStyleInf">2</span>" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "R.A. Theye" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Anesthesiology" "fecha" => "1970" "volumen" => "33" "paginaInicial" => "653" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/5477647" "web" => "Medline" ] ] ] ] ] ] ] ] 10 => array:3 [ "identificador" => "bib0055" "etiqueta" => "11." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Erythropoyetin and the regulation of erytropoyesis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "S.B. Krantz" 1 => "L.O. Jacobson" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Libro" => array:3 [ "fecha" => "1970" "editorial" => "University of Chicago Press" "editorialLocalizacion" => "Chicago" ] ] ] ] ] ] 11 => array:3 [ "identificador" => "bib0060" "etiqueta" => "12." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Mechanism of utilitation of oxygen" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "L. Garby" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:4 [ "tituloSerie" => "En «Problems of oxygen transport». Acta. Anaesth. Scand." "fecha" => "1971" "volumen" => "15" "paginaInicial" => "14" ] ] ] ] ] ] 12 => array:3 [ "identificador" => "bib0065" "etiqueta" => "13." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Oxygen affinity of whole-blood in normal human subjects" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "G. Artuson" 1 => "M. Robert" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Acta. Anaesth. Scan." "fecha" => "1971" "volumen" => "45" "numero" => "Suppl." "paginaInicial" => "22" ] ] ] ] ] ] 13 => array:3 [ "identificador" => "bib0070" "etiqueta" => "14." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The influence of temperature and pH on the dissociation curve of oxyhemoglobin of human blood" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "P. Astrup" 1 => "K. Engel" 2 => "J.W. Severinghaus" 3 => "E. Munson" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1080/00365516509083359" "Revista" => array:5 [ "tituloSerie" => "Scand. J. Clin. Lab. Invest." "fecha" => "1965" "volumen" => "17" "paginaInicial" => "515" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/5858746" "web" => "Medline" ] ] ] ] ] ] ] ] 14 => array:3 [ "identificador" => "bib0075" "etiqueta" => "15." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Die sogennante Standard O<span class="elsevierStyleInf">2</span> Dissoziationskurve des gesunden erwachsenen Mesnchen" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "H. Bartels" 1 => "K. Betke" 2 => "P. Hilpert" 3 => "G. Niemeyer" 4 => "K. Riegel" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:4 [ "tituloSerie" => "Plfügers Arch. ges. Physiol." "fecha" => "1961" "volumen" => "272" "paginaInicial" => "372" ] ] ] ] ] ] 15 => array:3 [ "identificador" => "bib0080" "etiqueta" => "16." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Adaptation to hypoxia" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "C. Lenfant" 1 => "J. Torrance" 2 => "R. Woodson" 3 => "C.A. Finch" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "LibroEditado" => array:3 [ "titulo" => "«Red cell Metalism and function»" "paginaInicial" => "203" "serieFecha" => "1970" ] ] ] ] ] ] 16 => array:3 [ "identificador" => "bib0085" "etiqueta" => "17." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The variation of blood oxygen dissociation curve in patients" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "N. Naeraa" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Scand. J. Clin. Lab. Invest." "fecha" => "1964" "volumen" => "16" "paginaInicial" => "630" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/14224487" "web" => "Medline" ] ] ] ] ] ] ] ] 17 => array:3 [ "identificador" => "bib0090" "etiqueta" => "18." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Lack of effect of high altitude on hemoglo bin oxygen affinity" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "J.W. Severinghaus" 1 => "R.B. Wiskopf" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "J. Appl. Physiol." "fecha" => "1972" "volumen" => "33" "paginaInicial" => "276" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/5054436" "web" => "Medline" ] ] ] ] ] ] ] ] 18 => array:3 [ "identificador" => "bib0095" "etiqueta" => "19." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Oxygen equilibrium curve of normal human blood and its evaluation by Adair's equation" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:7 [ 0 => "R.M. Winslow" 1 => "M.L. Svenberg" 2 => "R.L. Berger" 3 => "R.I. Shrager" 4 => "M. Luzzana" 5 => "M. Samaja" 6 => "L.I. Rossi bernard" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "J. Biol. Chem." "fecha" => "1977" "volumen" => "252" "paginaInicial" => "2331" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/849931" "web" => "Medline" ] ] ] ] ] ] ] ] 19 => array:3 [ "identificador" => "bib0100" "etiqueta" => "20." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The effect of organic phosphates from the human erytrocyte on the allosteric propertis of hemoglobin" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "R. Benesch" 1 => "R.E. Benesch" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Biochem. Biophys. Res. Commun." "fecha" => "1967" "volumen" => "26" "paginaInicial" => "162" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/6030262" "web" => "Medline" ] ] ] ] ] ] ] ] 20 => array:3 [ "identificador" => "bib0105" "etiqueta" => "21." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Intracellular organic phosphates as regulators of oxygen release by hemoglobin" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "R. Beneshc" 1 => "R.E. Benesch" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Nature. Lond." "fecha" => "1970" "volumen" => "221" "paginaInicial" => "618" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/5774935" "web" => "Medline" ] ] ] ] ] ] ] ] 21 => array:3 [ "identificador" => "bib0110" "etiqueta" => "22." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Effect of organic and inorganic phosphates on the oxygen equilibrium of human erytrocytes" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "A. Charnutin" 1 => "R.R. Curnish" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:4 [ "tituloSerie" => "Arch. Biochem. Biphys." "fecha" => "1967" "volumen" => "121" "paginaInicial" => "96" ] ] ] ] ] ] 22 => array:3 [ "identificador" => "bib0115" "etiqueta" => "23." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Regulatory mechanism of hemoglobin oxygen affinity in acidosis and alkalosis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "A.J. Bellinghan" 1 => "J.C. Detter" 2 => "C. Lenfant" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1172/JCI106540" "Revista" => array:5 [ "tituloSerie" => "J. Clin. Invest." "fecha" => "1971" "volumen" => "50" "paginaInicial" => "700" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/5545127" "web" => "Medline" ] ] ] ] ] ] ] ] 23 => array:3 [ "identificador" => "bib0120" "etiqueta" => "24." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Effects du 2,3 DPG sur la courve de dissociation de l’hemoglobine humaine" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "R. Benesch" 1 => "R.E. Benesch" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Nature" "fecha" => "1969" "volumen" => "221" "paginaInicial" => "618" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/5774935" "web" => "Medline" ] ] ] ] ] ] ] ] 24 => array:3 [ "identificador" => "bib0125" "etiqueta" => "25." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Binding of 2,3 DPG to human hemoglobin A. Effects of pH, hemoglobin concentration and carbon dio xide" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "L. Garby" 1 => "C.H. De verdier" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "LibroEditado" => array:2 [ "titulo" => "En «Oxygen affinity of hemoglobin and red cell acid base status». 236" "serieFecha" => "1972" ] ] ] ] ] ] 25 => array:3 [ "identificador" => "bib0130" "etiqueta" => "26." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Saturation dependency of the Böhr effect: interations among H<span class="elsevierStyleSup">+</span>, CO<span class="elsevierStyleInf">2</span>. and DPG" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "M.P. Hlastala" 1 => "R.D. Woodson" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "J. Appl. Physiol." "fecha" => "1975" "volumen" => "38" "paginaInicial" => "1126" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/237871" "web" => "Medline" ] ] ] ] ] ] ] ] 26 => array:3 [ "identificador" => "bib0135" "etiqueta" => "27." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Inhibition of CO2 combination and reduction of the Böhr effect in hemoglobin chemically modified at its amino groups" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "J.V. Kilmartin" 1 => "L. Rossibernardi" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Nature" "fecha" => "1969" "volumen" => "222" "paginaInicial" => "1243" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/5789658" "web" => "Medline" ] ] ] ] ] ] ] ] 27 => array:3 [ "identificador" => "bib0140" "etiqueta" => "28." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Stereochemistry of cooperative effects in hemoglobin" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "M.F. Perutz" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:4 [ "tituloSerie" => "Nature (London)" "fecha" => "1970" "volumen" => "228" "paginaInicial" => "726" ] ] ] ] ] ] 28 => array:3 [ "identificador" => "bib0145" "etiqueta" => "29." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Effect Böhr et affinité de l’hemoglo bine pour l’O<span class="elsevierStyleInf">2</span>" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "C.P. Poyart" 1 => "E. Bursaux" 2 => "A. Freminet" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:4 [ "tituloSerie" => ". Ann. Biol. Clin." "fecha" => "1972" "volumen" => "30" "paginaInicial" => "213" ] ] ] ] ] ] 29 => array:3 [ "identificador" => "bib0150" "etiqueta" => "30." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Displacement of oxygen dissocia tion curves and red eell cation exchange in chronic hypercapnia" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "K.E. Schaefer" 1 => "A.A. Messier" 2 => "C. Morcan" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:4 [ "tituloSerie" => "Resp. Physiol." "fecha" => "1970" "volumen" => "10" "paginaInicial" => "299" ] ] ] ] ] ] 30 => array:3 [ "identificador" => "bib0155" "etiqueta" => "31." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The Böhr effect and combination whit organic phosphates" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "M.F. Perutz" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:4 [ "tituloSerie" => "Nature (London)" "fecha" => "1970" "volumen" => "228" "paginaInicial" => "734" ] ] ] ] ] ] 31 => array:3 [ "identificador" => "bib0160" "etiqueta" => "32." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "A pausible secuence of the conformational changes of Hemo globin induced by oxygenation" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "J. Otsuka" 1 => "K.I. Takash" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:4 [ "tituloSerie" => "Arch. Biochem. Biophy." "fecha" => "1977" "volumen" => "179" "paginaInicial" => "706" ] ] ] ] ] ] 32 => array:3 [ "identificador" => "bib0165" "etiqueta" => "33." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The role of diphosphogliceric acid in the electrolyte equilibrium of blood cells" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "S. Rapoport" 1 => "G.M. Guest" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:4 [ "tituloSerie" => "J. Biol. Chemm." "fecha" => "1939" "volumen" => "131" "paginaInicial" => "675" ] ] ] ] ] ] 33 => array:3 [ "identificador" => "bib0170" "etiqueta" => "34." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Modifications sanguines transitoires de la glycolyse chez les malades hypercapniques ventilés artificillement" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "T. Garcia Carmona" 1 => "J.M. Polu" 2 => "C. Saunier" 3 => "P. Sadoul" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:4 [ "tituloSerie" => "Bull. Europ. Physiopath. resp." "fecha" => "1976" "volumen" => "12" "paginaInicial" => "199" ] ] ] ] ] ] 34 => array:3 [ "identificador" => "bib0175" "etiqueta" => "35." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Intermédiaires de la glycolise érythrocytaire au cours d’une hypercapnie de trois jours chez le chien" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "D. Hartemann" 1 => "P. Horsky" 2 => "T. Garcia carmona" 3 => "B. Hannhart" 4 => "C. Saunier" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:4 [ "tituloSerie" => "Bull eurp. Physiopath. resp." "fecha" => "1976" "volumen" => "12" "paginaInicial" => "185" ] ] ] ] ] ] 35 => array:3 [ "identificador" => "bib0180" "etiqueta" => "36." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "An equation for the oxygen hemo globin dissociation curve" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "A. Aberman" 1 => "J.M. Cavanilles" 2 => "J. Trotter" 3 => "D. Erbeck" 4 => "M.H. Weil" 5 => "H. Shubin" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J. Appl. Physiol." "fecha" => "1973" "volumen" => "35" "paginaInicial" => "570" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/4743020" "web" => "Medline" ] ] "itemHostRev" => array:3 [ "pii" => "S0140673613622278" "estado" => "S300" "issn" => "01406736" ] ] ] ] ] ] ] 36 => array:3 [ "identificador" => "bib0185" "etiqueta" => "37." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Blood P<span class="elsevierStyleInf">50</span> calculated from a single measurement of pH, PO<span class="elsevierStyleInf">2</span>" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "A. Aberman" 1 => "J.M. Cavanilles" 2 => "M.H. Weil" 3 => "H. Shubin" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "J. Appl. Physiol." "fecha" => "1975" "volumen" => "38" "paginaInicial" => "171" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/234122" "web" => "Medline" ] ] ] ] ] ] ] ] 37 => array:3 [ "identificador" => "bib0190" "etiqueta" => "38." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "An oxyhemoglobin dissociation analyzer" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "M.A. Duvelleroy" 1 => "R.G. Buckles" 2 => "S. Rosenkaimer" 3 => "C. Tung" 4 => "M.B. Laver" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "J. Appl. Physiol." "fecha" => "1970" "volumen" => "28" "paginaInicial" => "227" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/5413311" "web" => "Medline" ] ] ] ] ] ] ] ] 38 => array:3 [ "identificador" => "bib0195" "etiqueta" => "39." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Simplified method for determining the P50 of blood" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "B.W. Kirk" 1 => "M.B. Raber" 2 => "K.R. Duke" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "J. Appl. Physiol." "fecha" => "1975" "volumen" => "38" "paginaInicial" => "1140" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/237872" "web" => "Medline" ] ] ] ] ] ] ] ] 39 => array:3 [ "identificador" => "bib0200" "etiqueta" => "40." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The use of a single venous blood sample to assess oxygen binding to hemoglobin" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "M.A. Lichtman" 1 => "M. Murphy" 2 => "M. Pogal" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:4 [ "tituloSerie" => "Brith J. Haematol." "fecha" => "1976" "volumen" => "32" "paginaInicial" => "89" ] ] ] ] ] ] 40 => array:3 [ "identificador" => "bib0205" "etiqueta" => "41." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Effect of chronic hypoxic hypoxia on the O<span class="elsevierStyleInf">2</span>-Hb dissociation curve and respiratory gas transport in man" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "C. Lenfant" 1 => "P. Ways" 2 => "C. Aucutt" 3 => "J. Cruz" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:4 [ "tituloSerie" => "Resp. Physiol." "fecha" => "1969" "volumen" => "7" "paginaInicial" => "7" ] ] ] ] ] ] 41 => array:3 [ "identificador" => "bib0210" "etiqueta" => "42." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Adaptation to high altitude" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "C. Lenfant" 1 => "K. Sullivan" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1056/NEJM197102112840604" "Revista" => array:5 [ "tituloSerie" => "New Engl. J. Med." "fecha" => "1971" "volumen" => "284" "paginaInicial" => "298" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/4992716" "web" => "Medline" ] ] ] ] ] ] ] ] 42 => array:3 [ "identificador" => "bib0215" "etiqueta" => "43." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Shift of the O<span class="elsevierStyleInf">2</span>-Hb dissocia tion curve at altitude: mechanism and effect" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "C. Lenfant" 1 => "J.D. Torrance" 2 => "C. Reynafarje" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "J. Appl. Physiol." "fecha" => "1971" "volumen" => "30" "paginaInicial" => "625" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/5572784" "web" => "Medline" ] ] ] ] ] ] ] ] 43 => array:3 [ "identificador" => "bib0220" "etiqueta" => "44." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:1 [ "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "M. Rorth" 1 => "S.F. Nygaard" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "LibroEditado" => array:3 [ "titulo" => "Phosphate metabolism of the red cell during exposure to high altitude. En «Oxygen affinity of hemoglobin and red cell acid base status»" "paginaInicial" => "600" "serieFecha" => "1972" ] ] ] ] ] ] 44 => array:3 [ "identificador" => "bib0225" "etiqueta" => "45." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Adaptation to exercise: role of hemoglobin affinity for oxygen and 2, 3 diphosphoglycerate" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "S.D. Shapell" 1 => "J.A. Murray" 2 => "A.J. Bellinghan" 3 => "R.D. Woodson" 4 => "J.C. Detter" 5 => "C. Lenfant" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "J. Appl. Physiol." "fecha" => "1971" "volumen" => "30" "paginaInicial" => "827" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/5580800" "web" => "Medline" ] ] ] ] ] ] ] ] 45 => array:3 [ "identificador" => "bib0230" "etiqueta" => "46." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "2,3 Diphosphoglycerate concentrations and the dissociation of oxyhaemoglobin ventilatory failure" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "L.J. Fairweather" 1 => "J. Walker" 2 => "D.C. Flenley" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Clin. Sci. Mol. Med." "fecha" => "1974" "volumen" => "47" "paginaInicial" => "577" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/4448040" "web" => "Medline" ] ] ] ] ] ] ] ] 46 => array:3 [ "identificador" => "bib0235" "etiqueta" => "47." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Oxygen affinity in vivo and in vitro in chronic ventilatory failure" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "P.M. Tweeddale" 1 => "R.J.E. Leggett" 2 => "D. Flenley" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Clin. Sci. Mol. Med." "fecha" => "1977" "volumen" => "52" "paginaInicial" => "277" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/844259" "web" => "Medline" ] ] ] ] ] ] ] ] 47 => array:3 [ "identificador" => "bib0240" "etiqueta" => "48." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Improved oxy gen release: an adaptation of mature red cells to hypoxia" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "M.J. Edwards" 1 => "M.J. Novy" 2 => "C.L. Walters" 3 => "J. Wetcalfe" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1172/JCI105875" "Revista" => array:5 [ "tituloSerie" => "J. Clin. Invest." "fecha" => "1968" "volumen" => "47" "paginaInicial" => "1851" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/5666114" "web" => "Medline" ] ] ] ] ] ] ] ] 48 => array:3 [ "identificador" => "bib0245" "etiqueta" => "49." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Mean red cell age as determinant of blood oxygen affinity" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "M.J. Edwards" 1 => "B. Canon" 2 => "J. Albertson" 3 => "R.M. Bigley" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:4 [ "tituloSerie" => "Na ture. (Lond)" "fecha" => "1971" "volumen" => "230" "paginaInicial" => "583" ] ] ] ] ] ] 49 => array:3 [ "identificador" => "bib0250" "etiqueta" => "50." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:1 [ "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "C.R. Valery" 1 => "C.G. Zaroulis" 2 => "N.L. Portier" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "LibroEditado" => array:3 [ "titulo" => "Peripheral red cell as a functional biopsy to determine tissue oxygen tension. En «Oxygen affinity of hemoglobin and red cell acid base status»" "paginaInicial" => "650" "serieFecha" => "1972" ] ] ] ] ] ] 50 => array:3 [ "identificador" => "bib0255" "etiqueta" => "51." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The oxyhemoglobin dissociation curve in hypercapnie patients" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "A. Agostini" 1 => "M.D. Stabilini" 2 => "C. Be-rasconi" 3 => "G.C. Gerli" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Amer. Heart J." "fecha" => "1974" "volumen" => "87" "paginaInicial" => "670" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/4818711" "web" => "Medline" ] ] ] ] ] ] ] ] 51 => array:3 [ "identificador" => "bib0260" "etiqueta" => "52." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The content of 2,3 diphosphoglycerate and some other phospho-compounds in human erythrocyte from healthy adults and sub-jects with different types of anaemia" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "M. Hjelm" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:4 [ "tituloSerie" => "Forsvarmedicin" "fecha" => "1969" "volumen" => "5" "paginaInicial" => "219" ] ] ] ] ] ] 52 => array:3 [ "identificador" => "bib0265" "etiqueta" => "53." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The effect of cardiac disease on hemoglobin-oxygen binding" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "R.D. Woodson" 1 => "J.D. Torrance" 2 => "S.D. Shappel" 3 => "C. Lenfant" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1172/JCI106351" "Revista" => array:5 [ "tituloSerie" => "J. Clin. Invest." "fecha" => "1970" "volumen" => "49" "paginaInicial" => "1349" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/5432370" "web" => "Medline" ] ] ] ] ] ] ] ] 53 => array:3 [ "identificador" => "bib0270" "etiqueta" => "54." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Intraerythrocytic adaptation to anemia" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "J. Torrance" 1 => "P. Jacobs" 2 => "A. Restrepo" 3 => "J. Eschbach" 4 => "C. Lenfant" 5 => "C.A. Finch" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1056/NEJM197007232830402" "Revista" => array:5 [ "tituloSerie" => "New Engl. J. Med." "fecha" => "1970" "volumen" => "283" "paginaInicial" => "165" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/5424006" "web" => "Medline" ] ] ] ] ] ] ] ] 54 => array:3 [ "identificador" => "bib0275" "etiqueta" => "55." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The equilibrium of carbon monoxide with human hemoglobin in whole blood.Ann" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "F.J.W. Roughton" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:4 [ "tituloSerie" => "N.Y. Aca. Sci." "fecha" => "1970" "volumen" => "174" "paginaInicial" => "177" ] ] ] ] ] ] 55 => array:3 [ "identificador" => "bib0280" "etiqueta" => "56." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Detective gas transport function of stored red blood cells" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "D.J. Valtis" 1 => "A.C. Kennedy" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/S2215-0366(14)70295-0" "Revista" => array:5 [ "tituloSerie" => "Lancet." "fecha" => "1954" "volumen" => "1" "paginaInicial" => "119" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/26360574" "web" => "Medline" ] ] ] ] ] ] ] ] 56 => array:3 [ "identificador" => "bib0285" "etiqueta" => "57." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Maintenance of a normal oxygen transport function of sotred red cells" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "C.H. De verdier" 1 => "L. Garby" 2 => "M. Hjelm" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:4 [ "tituloSerie" => "I Theoretical aspects. Forsvarsmedicín" "fecha" => "1969" "volumen" => "5" "paginaInicial" => "244" ] ] ] ] ] ] 57 => array:3 [ "identificador" => "bib0290" "etiqueta" => "58." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Optimal use of different storage procedures" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "C.F. Hogman" 1 => "O. Akerblom" 2 => "C.H. De verdier" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:4 [ "tituloSerie" => "Bibl. haemat." "fecha" => "1971" "volumen" => "38" "paginaInicial" => "175" ] ] ] ] ] ] 58 => array:3 [ "identificador" => "bib0295" "etiqueta" => "59." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Experimentally induced in vivo alteration in the affinity of hemoglobin for oxygen" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "F. Oski" 1 => "H. Sugerman" 2 => "T. Pollock" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:4 [ "tituloSerie" => "Blood." "fecha" => "1971" "volumen" => "38" "paginaInicial" => "794" ] ] ] ] ] ] 59 => array:3 [ "identificador" => "bib0300" "etiqueta" => "60." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Mechanism of utilization of oxygen En «Problems of oxygen transport»" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "L. Garby" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:4 [ "tituloSerie" => "Act. Anaeslh. Scand." "fecha" => "1971" "volumen" => "15" "paginaInicial" => "11" ] ] ] ] ] ] 60 => array:3 [ "identificador" => "bib0305" "etiqueta" => "61." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Oxygen affinities of cellular respiration" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "B. Chance" 1 => "R. Thurman" 2 => "M. Gosalvez" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:4 [ "tituloSerie" => "Forsvarsmedicin" "fecha" => "1969" "volumen" => "5" "paginaInicial" => "235" ] ] ] ] ] ] 61 => array:3 [ "identificador" => "bib0310" "etiqueta" => "62." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Le metabolisme cellulaire et sa régulation." "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "G. Cohen" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Libro" => array:4 [ "fecha" => "1971" "paginaInicial" => "47" "editorial" => "Herman. Edit" "editorialLocalizacion" => "Paris" ] ] ] ] ] ] 62 => array:3 [ "identificador" => "bib0315" "etiqueta" => "63." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The blood lactatepiruvate relation-ship in varius physiologic and pathologic states" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "G.A. Goldsmith" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:4 [ "tituloSerie" => "Amer. J. Sci." "fecha" => "1948" "volumen" => "215" "paginaInicial" => "182" ] ] ] ] ] ] 63 => array:3 [ "identificador" => "bib0320" "etiqueta" => "64." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Control of concen tration gradients of pyruvate and lactante across cell membranes in blood" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "W.E. Huckabee" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "J. Appl. Physiol." "fecha" => "1956" "volumen" => "9" "paginaInicial" => "163" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/13376422" "web" => "Medline" ] ] ] ] ] ] ] ] 64 => array:3 [ "identificador" => "bib0325" "etiqueta" => "65." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Abnormal resting blood lactate; the significance of hyperlactacidemia in hospitalized patients: lactings blood acidosis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "W.E. Huckabee" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:4 [ "tituloSerie" => "Amer. J. Med." "fecha" => "1961" "volumen" => "30" "paginaInicial" => "833" ] ] ] ] ] ] 65 => array:3 [ "identificador" => "bib0330" "etiqueta" => "66." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Organic acids and calcium in hyperventilation" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "D.R. Axelrod" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:4 [ "tituloSerie" => "J. Appl. Physiol." "fecha" => "1961" "volumen" => "16" "paginaInicial" => "709" ] ] ] ] ] ] 66 => array:3 [ "identificador" => "bib0335" "etiqueta" => "67." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Primary hypocapnia: a cause of metabolic acidosis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "A. Eichenholz" 1 => "R.O. Mulhausen" 2 => "W.E. Anderson" 3 => "F.M. Macdonald" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "J. Appl. Physiol." "fecha" => "1962" "volumen" => "17" "paginaInicial" => "283" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/13889551" "web" => "Medline" ] ] ] ] ] ] ] ] 67 => array:3 [ "identificador" => "bib0340" "etiqueta" => "68." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The effects of hypercapnia and hypocapnia upon the cerebroespinal fluid lactate and pyruvate concentrations and upon the lactate, pyruvate ATP, ADP, phosphocreatine concentrations of cat brain tissue" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "L. Granholm" 1 => "B.K. Siesjo" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1111/j.1748-1716.1969.tb04379.x" "Revista" => array:5 [ "tituloSerie" => "Acta Physiol. Scand." "fecha" => "1969" "volumen" => "75" "paginaInicial" => "257" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/5790218" "web" => "Medline" ] ] ] ] ] ] ] ] 68 => array:3 [ "identificador" => "bib0345" "etiqueta" => "69." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Hyperlactatemia of hyperventila tion" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "D.T. Zborowska-Slius" 1 => "J.B. Dossetter" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "J. Appl. Physiol." "fecha" => "1967" "volumen" => "22" "paginaInicial" => "746" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/6023188" "web" => "Medline" ] ] ] ] ] ] ] ] 69 => array:3 [ "identificador" => "bib0350" "etiqueta" => "70." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "L’acidose lactique" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "R. Assan" 1 => "M. Derot" 2 => "G. Rosselin" 3 => "J. Reynier" 4 => "G. Tchobrousiski" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Presse méd." "fecha" => "1965" "volumen" => "73" "paginaInicial" => "1269" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/14273210" "web" => "Medline" ] ] ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "es" "url" => "/03002896/0000001500000004/v1_201509151302/S0300289615325321/v1_201509151302/es/main.assets" "Apartado" => array:4 [ "identificador" => "43834" "tipo" => "SECCION" "es" => array:2 [ "titulo" => "Revisión de conjunto" "idiomaDefecto" => true ] "idiomaDefecto" => "es" ] "PDF" => "https://static.elsevier.es/multimedia/03002896/0000001500000004/v1_201509151302/S0300289615325321/v1_201509151302/es/main.pdf?idApp=UINPBA00003Z&text.app=https://archbronconeumol.org/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289615325321?idApp=UINPBA00003Z" ]
| Year/Month | Html | Total | |
|---|---|---|---|
| 2024 November | 3 | 5 | 8 |
| 2024 October | 89 | 49 | 138 |
| 2024 September | 77 | 42 | 119 |
| 2024 August | 61 | 44 | 105 |
| 2024 July | 49 | 41 | 90 |
| 2024 June | 64 | 32 | 96 |
| 2024 May | 75 | 39 | 114 |
| 2024 April | 58 | 61 | 119 |
| 2024 March | 66 | 52 | 118 |
| 2024 February | 64 | 100 | 164 |
| 2024 January | 0 | 5 | 5 |
| 2023 December | 0 | 19 | 19 |
| 2023 November | 0 | 44 | 44 |
| 2023 October | 0 | 21 | 21 |
| 2023 September | 0 | 24 | 24 |
| 2023 August | 0 | 21 | 21 |
| 2023 July | 0 | 16 | 16 |
| 2023 May | 0 | 2 | 2 |
| 2023 April | 0 | 5 | 5 |
| 2023 March | 5 | 119 | 124 |
| 2023 February | 26 | 662 | 688 |
| 2023 January | 23 | 375 | 398 |
| 2022 December | 36 | 398 | 434 |
| 2022 November | 43 | 813 | 856 |
| 2022 October | 28 | 820 | 848 |
| 2022 September | 26 | 769 | 795 |
| 2022 August | 28 | 514 | 542 |
| 2022 July | 29 | 495 | 524 |
| 2022 June | 32 | 633 | 665 |
| 2022 May | 45 | 974 | 1019 |
| 2022 April | 48 | 935 | 983 |
| 2022 March | 43 | 970 | 1013 |
| 2022 February | 36 | 761 | 797 |
| 2022 January | 34 | 345 | 379 |
| 2021 December | 18 | 333 | 351 |
| 2021 November | 22 | 641 | 663 |
| 2021 October | 24 | 880 | 904 |
| 2021 September | 18 | 576 | 594 |
| 2021 August | 13 | 528 | 541 |
| 2021 July | 14 | 587 | 601 |
| 2021 June | 23 | 762 | 785 |
| 2021 May | 25 | 938 | 963 |
| 2021 April | 42 | 3000 | 3042 |
| 2021 March | 48 | 1721 | 1769 |
| 2021 February | 42 | 932 | 974 |
| 2021 January | 31 | 854 | 885 |
| 2020 December | 40 | 857 | 897 |
| 2020 November | 14 | 1667 | 1681 |
| 2020 October | 28 | 1612 | 1640 |
| 2020 September | 20 | 1314 | 1334 |
| 2020 August | 26 | 1183 | 1209 |
| 2020 July | 17 | 987 | 1004 |
| 2020 June | 23 | 1657 | 1680 |
| 2020 May | 22 | 2140 | 2162 |
| 2020 April | 32 | 2288 | 2320 |
| 2020 March | 17 | 1675 | 1692 |
| 2020 February | 24 | 858 | 882 |
| 2020 January | 35 | 432 | 467 |
| 2019 December | 25 | 421 | 446 |
| 2019 November | 14 | 982 | 996 |
| 2019 October | 19 | 1090 | 1109 |
| 2019 September | 19 | 818 | 837 |
| 2019 August | 19 | 533 | 552 |
| 2019 July | 18 | 418 | 436 |
| 2019 June | 23 | 415 | 438 |
| 2019 May | 17 | 265 | 282 |
| 2019 April | 58 | 105 | 163 |
| 2019 March | 11 | 79 | 90 |
| 2019 February | 6 | 53 | 59 |
| 2019 January | 8 | 37 | 45 |
| 2018 December | 6 | 33 | 39 |
| 2018 November | 24 | 42 | 66 |
| 2018 October | 21 | 34 | 55 |
| 2018 September | 12 | 44 | 56 |
| 2018 July | 0 | 1 | 1 |
| 2018 May | 7 | 2 | 9 |
| 2018 April | 12 | 14 | 26 |
| 2018 March | 8 | 8 | 16 |
| 2018 February | 6 | 31 | 37 |
| 2018 January | 7 | 22 | 29 |
| 2017 December | 17 | 28 | 45 |
| 2017 November | 3 | 35 | 38 |
| 2017 October | 8 | 27 | 35 |
| 2017 September | 7 | 22 | 29 |
| 2017 August | 18 | 27 | 45 |
| 2017 July | 7 | 26 | 33 |
| 2017 June | 17 | 44 | 61 |
| 2017 May | 13 | 30 | 43 |
| 2017 April | 16 | 30 | 46 |
| 2017 March | 8 | 68 | 76 |
| 2017 February | 11 | 34 | 45 |
| 2017 January | 6 | 11 | 17 |
| 2016 December | 12 | 18 | 30 |
| 2016 November | 8 | 18 | 26 |
| 2016 October | 14 | 35 | 49 |
| 2016 September | 19 | 22 | 41 |
| 2016 August | 26 | 10 | 36 |
| 2016 July | 16 | 9 | 25 |
| 2016 June | 28 | 13 | 41 |
| 2016 May | 17 | 9 | 26 |
| 2016 April | 7 | 1 | 8 |
| 2016 March | 10 | 0 | 10 |
| 2016 February | 8 | 5 | 13 |
| 2016 January | 22 | 13 | 35 |
| 2015 December | 35 | 25 | 60 |
| 2015 November | 33 | 13 | 46 |
| 2015 October | 8 | 2 | 10 |
| 2015 September | 1 | 0 | 1 |
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