Pulmonary Sarcoidosis: A disease characterized and perpetuated by acute lung T-lymphocites
R.G. Crystal, W.C. Roberts, G.W. Hunninghake, J.E. Gadek, J.D. Fulmer, B.R. Line
Read
2755
Timeswas read the article
1310
Total PDF
1445
Total HTML
Share statistics
array:23 [ "pii" => "S0300289615323814" "issn" => "03002896" "doi" => "10.1016/S0300-2896(15)32381-4" "estado" => "S300" "fechaPublicacion" => "1982-03-01" "aid" => "72451" "copyright" => "Sociedad Española de Neumología y Cirugía Torácica" "copyrightAnyo" => "1982" "documento" => "simple-article" "crossmark" => 0 "subdocumento" => "abs" "cita" => "Arch Bronconeumol. 1982;18:118" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 983 "formatos" => array:3 [ "EPUB" => 57 "HTML" => 505 "PDF" => 421 ] ] "itemSiguiente" => array:18 [ "pii" => "S0300289615323826" "issn" => "03002896" "doi" => "10.1016/S0300-2896(15)32382-6" "estado" => "S300" "fechaPublicacion" => "1982-03-01" "aid" => "72452" "copyright" => "Sociedad Española de Neumología y Cirugía Torácica" "documento" => "simple-article" "crossmark" => 0 "subdocumento" => "abs" "cita" => "Arch Bronconeumol. 1982;18:118" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 1012 "formatos" => array:3 [ "EPUB" => 51 "HTML" => 501 "PDF" => 460 ] ] "es" => array:9 [ "idiomaDefecto" => true "titulo" => "Sperm abnormalities and cigarette smoking" "tienePdf" => "es" "tieneTextoCompleto" => 0 "tieneResumen" => "es" "paginas" => array:1 [ 0 => array:1 [ "paginaInicial" => "118" ] ] "contieneResumen" => array:1 [ "es" => true ] "contienePdf" => array:1 [ "es" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "H.J. Evans, J. Fletcher, M. Torrance, T.B. Hargreave" "autores" => array:4 [ 0 => array:2 [ "nombre" => "H.J." "apellidos" => "Evans" ] 1 => array:2 [ "nombre" => "J." "apellidos" => "Fletcher" ] 2 => array:2 [ "nombre" => "M." "apellidos" => "Torrance" ] 3 => array:2 [ "nombre" => "T.B." "apellidos" => "Hargreave" ] ] ] ] ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289615323826?idApp=UINPBA00003Z" "url" => "/03002896/0000001800000002/v1_201509151137/S0300289615323826/v1_201509151137/es/main.assets" ] "itemAnterior" => array:18 [ "pii" => "S0300289615323802" "issn" => "03002896" "doi" => "10.1016/S0300-2896(15)32380-2" "estado" => "S300" "fechaPublicacion" => "1982-03-01" "aid" => "72450" "copyright" => "Sociedad Española de Neumología y Cirugía Torácica" "documento" => "simple-article" "crossmark" => 0 "subdocumento" => "abs" "cita" => "Arch Bronconeumol. 1982;18:118" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 1113 "formatos" => array:3 [ "EPUB" => 52 "HTML" => 529 "PDF" => 532 ] ] "es" => array:8 [ "idiomaDefecto" => true "titulo" => "Long term domiciliary oxygen therapy in chronic hypoxic cor pulmonale complicating chronic bronchitis and emphysema" "tienePdf" => "es" "tieneTextoCompleto" => 0 "tieneResumen" => "es" "paginas" => array:1 [ 0 => array:1 [ "paginaInicial" => "118" ] ] "contieneResumen" => array:1 [ "es" => true ] "contienePdf" => array:1 [ "es" => true ] ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289615323802?idApp=UINPBA00003Z" "url" => "/03002896/0000001800000002/v1_201509151137/S0300289615323802/v1_201509151137/es/main.assets" ] "es" => array:9 [ "idiomaDefecto" => true "titulo" => "Pulmonary Sarcoidosis: A disease characterized and perpetuated by acute lung T-lymphocites" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:1 [ "paginaInicial" => "118" ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "R.G. Crystal, W.C. Roberts, G.W. Hunninghake, J.E. Gadek, J.D. Fulmer, B.R. Line" "autores" => array:6 [ 0 => array:2 [ "nombre" => "R.G." "apellidos" => "Crystal" ] 1 => array:2 [ "nombre" => "W.C." "apellidos" => "Roberts" ] 2 => array:2 [ "nombre" => "G.W." "apellidos" => "Hunninghake" ] 3 => array:2 [ "nombre" => "J.E." "apellidos" => "Gadek" ] 4 => array:2 [ "nombre" => "J.D." "apellidos" => "Fulmer" ] 5 => array:2 [ "nombre" => "B.R." "apellidos" => "Line" ] ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "tieneResumen" => true "resumen" => array:1 [ "es" => array:1 [ "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">La alveolitis de la sarcoidosis pulmonar se caracteriza por un infiltrado intenso de células mononucleares que precede probablemente al granuloma. Los mecanismos patogénicos que desencadenan la sarcoidosis pueden mostrarse estudiando las células mononucleares que componen la alveolitis. El lavado broncoalveolar ha mostrado que el pulmón sarcoide posee un elevado número de linfocitos T activados en los alveolos. En contraste con los linfocitos del sujeto normal, los del enfermo con sarcoidosis eliminan un mediador, factor quemotáctico de monocitos, que probablemente contribuye a la patogénesis de la sarcoidosis, atrayendo a los monocitos sanguíneos hacia el pulmón y construyendo así el futuro granuloma. Los monitores convencionales de la actividad de la sarcoidosis, como test serológicos, funcionales, radiografías muestran escasa relación con la alveolitis de linfocitos T manifestada con el lavado broncoalveolar o con estudios histopatológicos. En contraste, la cuantificación de linfocitos T del lavado bronquial y el escintigrama con galio del pulmón se muestran métodos sensitivos y específicos de controlar la actividad de la alveolitis de la sarcoidosis pulmonar y puede ser útil en el tratamiento.</p></span>" ] ] ] "idiomaDefecto" => "es" "url" => "/03002896/0000001800000002/v1_201509151137/S0300289615323814/v1_201509151137/es/main.assets" "Apartado" => array:4 [ "identificador" => "43822" "tipo" => "SECCION" "es" => array:2 [ "titulo" => "Referatas" "idiomaDefecto" => true ] "idiomaDefecto" => "es" ] "PDF" => "https://static.elsevier.es/multimedia/03002896/0000001800000002/v1_201509151137/S0300289615323814/v1_201509151137/es/main.pdf?idApp=UINPBA00003Z&text.app=https://archbronconeumol.org/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289615323814?idApp=UINPBA00003Z" ]
| Year/Month | Html | Total | |
|---|---|---|---|
| 2024 November | 5 | 1 | 6 |
| 2024 October | 36 | 14 | 50 |
| 2024 September | 33 | 15 | 48 |
| 2024 August | 60 | 28 | 88 |
| 2024 July | 49 | 20 | 69 |
| 2024 June | 52 | 20 | 72 |
| 2024 May | 43 | 25 | 68 |
| 2024 April | 47 | 22 | 69 |
| 2024 March | 36 | 17 | 53 |
| 2024 February | 37 | 41 | 78 |
| 2023 March | 14 | 3 | 17 |
| 2023 February | 25 | 25 | 50 |
| 2023 January | 33 | 27 | 60 |
| 2022 December | 24 | 14 | 38 |
| 2022 November | 27 | 17 | 44 |
| 2022 October | 24 | 20 | 44 |
| 2022 September | 15 | 20 | 35 |
| 2022 August | 24 | 27 | 51 |
| 2022 July | 14 | 29 | 43 |
| 2022 June | 18 | 33 | 51 |
| 2022 May | 21 | 24 | 45 |
| 2022 April | 21 | 26 | 47 |
| 2022 March | 18 | 29 | 47 |
| 2022 February | 17 | 16 | 33 |
| 2022 January | 20 | 22 | 42 |
| 2021 December | 10 | 29 | 39 |
| 2021 November | 13 | 21 | 34 |
| 2021 October | 15 | 33 | 48 |
| 2021 September | 11 | 32 | 43 |
| 2021 August | 4 | 14 | 18 |
| 2021 July | 9 | 19 | 28 |
| 2021 June | 15 | 19 | 34 |
| 2021 May | 4 | 20 | 24 |
| 2021 April | 12 | 41 | 53 |
| 2021 March | 13 | 10 | 23 |
| 2021 February | 22 | 11 | 33 |
| 2021 January | 15 | 11 | 26 |
| 2020 December | 9 | 12 | 21 |
| 2020 November | 7 | 14 | 21 |
| 2020 October | 4 | 4 | 8 |
| 2020 September | 4 | 4 | 8 |
| 2020 August | 10 | 5 | 15 |
| 2020 July | 12 | 10 | 22 |
| 2020 June | 9 | 6 | 15 |
| 2020 May | 7 | 9 | 16 |
| 2020 April | 9 | 7 | 16 |
| 2020 March | 9 | 16 | 25 |
| 2020 February | 14 | 9 | 23 |
| 2020 January | 14 | 12 | 26 |
| 2019 December | 13 | 17 | 30 |
| 2019 November | 3 | 2 | 5 |
| 2019 October | 12 | 10 | 22 |
| 2019 September | 16 | 8 | 24 |
| 2019 August | 12 | 16 | 28 |
| 2019 July | 3 | 6 | 9 |
| 2019 June | 6 | 0 | 6 |
| 2019 May | 8 | 9 | 17 |
| 2019 April | 8 | 10 | 18 |
| 2019 March | 5 | 9 | 14 |
| 2019 February | 3 | 10 | 13 |
| 2019 January | 2 | 4 | 6 |
| 2018 December | 4 | 10 | 14 |
| 2018 November | 0 | 6 | 6 |
| 2018 October | 12 | 11 | 23 |
| 2018 September | 5 | 4 | 9 |
| 2018 July | 0 | 1 | 1 |
| 2018 May | 8 | 2 | 10 |
| 2018 April | 11 | 9 | 20 |
| 2018 March | 7 | 9 | 16 |
| 2018 February | 8 | 14 | 22 |
| 2018 January | 2 | 10 | 12 |
| 2017 December | 10 | 12 | 22 |
| 2017 November | 9 | 11 | 20 |
| 2017 October | 4 | 11 | 15 |
| 2017 September | 8 | 13 | 21 |
| 2017 August | 14 | 13 | 27 |
| 2017 July | 7 | 10 | 17 |
| 2017 June | 10 | 20 | 30 |
| 2017 May | 13 | 6 | 19 |
| 2017 April | 12 | 9 | 21 |
| 2017 March | 8 | 6 | 14 |
| 2017 February | 8 | 5 | 13 |
| 2017 January | 6 | 5 | 11 |
| 2016 December | 12 | 6 | 18 |
| 2016 November | 19 | 14 | 33 |
| 2016 October | 17 | 20 | 37 |
| 2016 September | 13 | 7 | 20 |
| 2016 August | 16 | 11 | 27 |
| 2016 July | 13 | 6 | 19 |
| 2016 June | 11 | 5 | 16 |
| 2016 May | 10 | 5 | 15 |
| 2016 April | 8 | 1 | 9 |
| 2016 March | 7 | 1 | 8 |
| 2016 February | 13 | 2 | 15 |
| 2016 January | 17 | 7 | 24 |
| 2015 December | 31 | 16 | 47 |
| 2015 November | 28 | 6 | 34 |
| 2015 October | 8 | 2 | 10 |
| 2015 September | 1 | 0 | 1 |
Show all
