Statistics

 array:23 [
  "pii" => "S0300289615321098"
  "issn" => "03002896"
  "doi" => "10.1016/S0300-2896(15)32109-8"
  "estado" => "S300"
  "fechaPublicacion" => "1985-09-01"
  "aid" => "72179"
  "copyright" => "Sociedad Española de Neumología y Cirugía Torácica"
  "copyrightAnyo" => "1985"
  "documento" => "article"
  "crossmark" => 0
  "subdocumento" => "fla"
  "cita" => "Arch Bronconeumol. 1985;21:207-11"
  "abierto" => array:3 [
    "ES" => true
    "ES2" => true
    "LATM" => true
  ]
  "gratuito" => true
  "lecturas" => array:2 [
    "total" => 1036
    "formatos" => array:3 [
      "EPUB" => 47
      "HTML" => 542
      "PDF" => 447
    ]
  ]
  "itemSiguiente" => array:18 [
    "pii" => "S0300289615321104"
    "issn" => "03002896"
    "doi" => "10.1016/S0300-2896(15)32110-4"
    "estado" => "S300"
    "fechaPublicacion" => "1985-09-01"
    "aid" => "72180"
    "copyright" => "Sociedad Española de Neumología y Cirugía Torácica"
    "documento" => "article"
    "crossmark" => 0
    "subdocumento" => "fla"
    "cita" => "Arch Bronconeumol. 1985;21:212-6"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 1963
      "formatos" => array:3 [
        "EPUB" => 42
        "HTML" => 682
        "PDF" => 1239
      ]
    ]
    "es" => array:10 [
      "idiomaDefecto" => true
      "titulo" => "Recidiva del neumotorax espontaneo y su relacion con la presencia de bullas"
      "tienePdf" => "es"
      "tieneTextoCompleto" => 0
      "tieneResumen" => array:2 [
        0 => "es"
        1 => "en"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "212"
          "paginaFinal" => "216"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "en" => array:1 [
          "titulo" => "Recurrent spontaneous pneumothorax and the relationship with bullas"
        ]
      ]
      "contieneResumen" => array:2 [
        "es" => true
        "en" => true
      ]
      "contienePdf" => array:1 [
        "es" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "J. Torres Lanzas, J.J. Rivas de Andres"
          "autores" => array:2 [
            0 => array:2 [
              "nombre" => "J."
              "apellidos" => "Torres Lanzas"
            ]
            1 => array:2 [
              "nombre" => "J.J."
              "apellidos" => "Rivas de Andres"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "es"
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289615321104?idApp=UINPBA00003Z"
    "url" => "/03002896/0000002100000005/v1_201509151022/S0300289615321104/v1_201509151022/es/main.assets"
  ]
  "itemAnterior" => array:18 [
    "pii" => "S0300289615321086"
    "issn" => "03002896"
    "doi" => "10.1016/S0300-2896(15)32108-6"
    "estado" => "S300"
    "fechaPublicacion" => "1985-09-01"
    "aid" => "72178"
    "copyright" => "Sociedad Española de Neumología y Cirugía Torácica"
    "documento" => "article"
    "crossmark" => 0
    "subdocumento" => "fla"
    "cita" => "Arch Bronconeumol. 1985;21:202-6"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 1430
      "formatos" => array:3 [
        "EPUB" => 67
        "HTML" => 611
        "PDF" => 752
      ]
    ]
    "es" => array:10 [
      "idiomaDefecto" => true
      "titulo" => "Quistes broncogenicos. Presentacion de 16 casos y revision de la literatura"
      "tienePdf" => "es"
      "tieneTextoCompleto" => 0
      "tieneResumen" => array:2 [
        0 => "es"
        1 => "en"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "202"
          "paginaFinal" => "206"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "en" => array:1 [
          "titulo" => "Bronchogenic cyst. Presentation of 16 patients and review of the literature"
        ]
      ]
      "contieneResumen" => array:2 [
        "es" => true
        "en" => true
      ]
      "contienePdf" => array:1 [
        "es" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "M&#46;<span class="elsevierStyleSup">a</span>L&#46; Martinez Martinez, J&#46; Ruiz Manzano, L&#46; Joanmiquel Isern, L&#46; Bernado, J&#46; Astudillo, J&#46; Teixido"
          "autores" => array:6 [
            0 => array:2 [
              "nombre" => "M&#46;<span class="elsevierStyleSup">a</span>L&#46;"
              "apellidos" => "Martinez Martinez"
            ]
            1 => array:2 [
              "nombre" => "J&#46;"
              "apellidos" => "Ruiz Manzano"
            ]
            2 => array:2 [
              "nombre" => "L&#46;"
              "apellidos" => "Joanmiquel Isern"
            ]
            3 => array:2 [
              "nombre" => "L&#46;"
              "apellidos" => "Bernado"
            ]
            4 => array:2 [
              "nombre" => "J&#46;"
              "apellidos" => "Astudillo"
            ]
            5 => array:2 [
              "nombre" => "J&#46;"
              "apellidos" => "Teixido"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "es"
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289615321086?idApp=UINPBA00003Z"
    "url" => "/03002896/0000002100000005/v1_201509151022/S0300289615321086/v1_201509151022/es/main.assets"
  ]
  "es" => array:13 [
    "idiomaDefecto" => true
    "titulo" => "Nuestra experiencia en 36 casos de carcinoma indiferenciado de celulas peque&#241;as de pulmon"
    "tieneTextoCompleto" => 0
    "paginas" => array:1 [
      0 => array:2 [
        "paginaInicial" => "207"
        "paginaFinal" => "211"
      ]
    ]
    "autores" => array:1 [
      0 => array:3 [
        "autoresLista" => "M&#46;G&#46; Pallotta, M&#46;C&#46; Garcia, D&#46; Fantl, E&#46; Nucifora, A&#46; Precerutti"
        "autores" => array:5 [
          0 => array:2 [
            "nombre" => "M&#46;G&#46;"
            "apellidos" => "Pallotta"
          ]
          1 => array:2 [
            "nombre" => "M&#46;C&#46;"
            "apellidos" => "Garcia"
          ]
          2 => array:2 [
            "nombre" => "D&#46;"
            "apellidos" => "Fantl"
          ]
          3 => array:2 [
            "nombre" => "E&#46;"
            "apellidos" => "Nucifora"
          ]
          4 => array:2 [
            "nombre" => "A&#46;"
            "apellidos" => "Precerutti"
          ]
        ]
        "afiliaciones" => array:1 [
          0 => array:2 [
            "entidad" => "Secci&#243;n Hematolog&#237;a y Oncolog&#237;a&#46; Servicio de Cl&#237;nica M&#233;dica&#46; Hospital Italiano de Buenos Aires&#46; Buenos Aires"
            "identificador" => "aff0005"
          ]
        ]
      ]
    ]
    "titulosAlternativos" => array:1 [
      "en" => array:1 [
        "titulo" => "Our experience with 36 cases of undifferentiated small cell carcinoma of lung"
      ]
    ]
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "fechaRecibido" => "1984-09-25"
    "fechaAceptado" => "1985-04-08"
    "tieneResumen" => true
    "resumen" => array:2 [
      "es" => array:1 [
        "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Se presenta la experiencia en el diagn&#243;stico y seguimiento de 36 pacientes con carcinoma indiferenciado de c&#233;lulas peque&#241;as de pulm&#243;n &#40;CPCP&#41; en el Servicio de Clinica M&#233;dica&#44; Secci&#243;n Hematolog&#237;a y Oncolog&#237;a del Hospital Italiano de Buenos Aires&#44; durante el periodo 1978-1983&#46;</p><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">La poblaci&#243;n eran 31 hombres &#40;86&#44;1&#37;&#41; y 5 mujeres &#40;13&#44;9&#37;&#41;&#44; con un promedio de edad de 58&#44;6 a&#241;os&#46; El 88&#37; eran fumadores&#46; La mayor&#237;a se presentaron con s&#237;ntomas pulmonares como expresi&#243;n directa del tumor &#40;tos y hemoptisis&#41; y&#47;o extensi&#243;n a estructuras tor&#225;cicas &#40;s&#237;ndrome mediastinal&#44; s&#237;ndrome de vena cava&#41;&#46; El 11&#44;1&#37; tuvieron forma de expresi&#243;n s&#237;ndromes paraneopl&#225;sicos &#40;2 SSIHAD y 2 polineuropat&#237;as sensitivo motoras graves&#41;&#46;</p><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">En 17 casos la enfermedad fue considerada localizada a un hemit&#243;rax y en 19 casos diseminada &#40;enfermedad locorregional avanzada y&#47;o met&#225;stasis a distancia&#41;&#46; Asimismo el 55&#37; de los pacientes eran ambulatorios&#46;</p><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">De los 36 casos&#44; 21 fueron valorables en cuanto a respuesta a tratamiento quimio y radioterap&#233;utico&#46; Se lograron cinco remisiones completas&#44; todas ellas en pacientes localizados tratados con esquemas quimioterap&#233;uticos que inclu&#237;an adriamicina&#46; Hubieron seis remisiones parciales y 10 progresiones&#44; estas &#250;ltimas se dieron en pacientes diseminados&#46; La duraci&#243;n de la respuesta asl como la sobrevida tiene diferencias significativas entre los grupos localizados&#44; diseminados y progresiones&#44; con P mayor de 0&#44;025&#46;</p><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">La sobrevida global de 10 meses para todo el grupo tratado contrasta con la sobrevida referida en la literatura en la evoluci&#243;n natural de la enfermedad &#40;4 meses&#41;&#46; Esto hace importante el correcto diagn&#243;stico&#44; la b&#250;squeda de pacientes en estadios localizados&#44; como la aplicaci&#243;n de esquemas de poliquimioterapia con alto grado de respuesta&#46;</p></span>"
      ]
      "en" => array:1 [
        "resumen" => "<span id="abst0010" class="elsevierStyleSection elsevierViewall"><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">The experience in diagnosis and follow-up of 36 patients with undifferentiated small cell carcinoma of the lung at the Hematology Oncology Section of the Hospital de Buenos Aires during 1978-1983 is presented&#46;</p><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">They were 31 men &#40;86&#37;&#41; and 5 women &#40;14&#37;&#41;&#46; Mean age was 58&#46;6 years which of them to the tumor &#40;cough&#44; hemoptisis&#41; and&#47;or extension of the tumor to thoracic structures &#40;mediastinal or vein cava syndromes&#41;&#46;</p><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">Four patients presented with paraneoplastic syndrome &#40;2 cases of inadecuate secretion of antidiuretic hormone and 2 with severe sensory-motor polyneuropathy&#41;&#46; In 17 cases&#44; disease was localised to one hemithorax and in the remaining 19 it was disseminated&#46; 55&#37; of the patients were ambulatory&#46; Of the 36 patients 21 could be evaluated with radiochemotherapy&#46; In all cases&#44; tumor was localized and treatment included adriamycin&#46; Six patients had partial remissions&#46; Ten progressed and these were cases with disseminated disease&#46; There were significant differences in response to treatment and survival between the two groups &#40;disseminated vs&#46; localized&#41;&#46;</p><p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">An overall survival of 10 months in the group contrasts with shorter survival in other studies and emphasizes the need for a correct&#44; early diagnosis and the use of combined chemotherapy with chances of high response&#46;</p></span>"
      ]
    ]
    "bibliografia" => array:2 [
      "titulo" => "Bibliografia"
      "seccion" => array:1 [
        0 => array:2 [
          "identificador" => "bibs0005"
          "bibliografiaReferencia" => array:31 [
            0 => array:3 [
              "identificador" => "bib0005"
              "etiqueta" => "1&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Review&#46; Small cell carcinoma of the lung"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "R&#46; Livington"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Blood"
                        "fecha" => "1980"
                        "volumen" => "56"
                        "paginaInicial" => "575"
                        "paginaFinal" => "583"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/6251936"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib0010"
              "etiqueta" => "2&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Concept in cancer&#46; Small cell lung cancer"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "A&#46; Greco"
                            1 => "F&#46; Oldham"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:3 [
                        "tituloSerie" => "N Engl J Med"
                        "fecha" => "1979"
                        "paginaInicial" => "301"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib0015"
              "etiqueta" => "3&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Experiencia en diagn&#243;stico de c&#225;ncer de pulm&#243;n"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:1 [
                            0 => "H&#46; Garc&#237;a"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Libro" => array:1 [
                        "fecha" => "1978"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib0020"
              "etiqueta" => "4&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Small cell bronchogenic carcinoma&#58; a distint clinicopathologic entity"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:1 [
                            0 => "H&#46; Mart&#237;n"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Semin Oncol"
                        "fecha" => "1978"
                        "volumen" => "5"
                        "paginaInicial" => "234"
                        "paginaFinal" => "243"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/211637"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bib0025"
              "etiqueta" => "5&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Inadequacy of APUD concept&#46; In explaining productions of peptide hormones by tumours"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "R&#46; Stevens"
                            1 => "G&#46; Moore"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Lancet"
                        "fecha" => "1983"
                        "volumen" => "15"
                        "paginaInicial" => "118"
                        "paginaFinal" => "119"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            5 => array:3 [
              "identificador" => "bib0030"
              "etiqueta" => "6&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Comparative histopathologie&#44; histochemical&#44; electron microscopie and tissue culture studies of bronchial carcinoids and oat cell carcionomas of lung"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:1 [
                            0 => "Fischer"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "AJCP"
                        "fecha" => "1978"
                        "volumen" => "69"
                        "paginaInicial" => "165"
                        "paginaFinal" => "172"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/204185"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            6 => array:3 [
              "identificador" => "bib0035"
              "etiqueta" => "7&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Carcinomas of the lung&#58; an ultrastructural and immunological study"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "C&#46; Saba"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:4 [
                        "tituloSerie" => "AJCP"
                        "fecha" => "1978"
                        "volumen" => "80"
                        "paginaInicial" => "13"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            7 => array:3 [
              "identificador" => "bib0040"
              "etiqueta" => "8&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Small cell carcinoma of the lung&#58; celular origin and relationship to other neoplasm"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "A&#46;S&#46; Tischler"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "Semin Oncol"
                        "fecha" => "1978"
                        "volumen" => "5"
                        "paginaInicial" => "244"
                        "paginaFinal" => "252"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/29340"
                            "web" => "Medline"
                          ]
                        ]
                        "itemHostRev" => array:3 [
                          "pii" => "S1474442212702648"
                          "estado" => "S300"
                          "issn" => "14744422"
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            8 => array:3 [
              "identificador" => "bib0045"
              "etiqueta" => "9&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Changes in morphologic and biochemical characteristics of small cell carcinoma of the lung&#46; A clinicopathology study"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:1 [
                            0 => "M&#46;D&#46; Abeloff"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Am J Med"
                        "fecha" => "1979"
                        "volumen" => "66"
                        "paginaInicial" => "757"
                        "paginaFinal" => "764"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/220872"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            9 => array:3 [
              "identificador" => "bib0050"
              "etiqueta" => "10&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Five years follow up the medical research council comparative trial of surgery and radiotherapy for the primary treatment of small celled or coated carcinoma of the bronches"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:1 [
                            0 => "A&#46; Miller"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:4 [
                        "tituloSerie" => "Lancet"
                        "fecha" => "1969"
                        "volumen" => "46"
                        "paginaInicial" => "501"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            10 => array:3 [
              "identificador" => "bib0055"
              "etiqueta" => "11&#46;"
              "referencia" => array:1 [
                0 => array:1 [
                  "referenciaCompleta" => "Mountain Clifton F&#46; Tratamiento quir&#250;rgico en el c&#225;ncer de pulm&#243;n&#58; determinantes biol&#243;gicos&#44; fisiol&#243;gicos y t&#233;cnicos&#46; Semin Oncol&#46;"
                ]
              ]
            ]
            11 => array:3 [
              "identificador" => "bib0160"
              "etiqueta" => "12&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Small cell carcinoma of the lung&#46; Clinicopathologic study"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:1 [
                            0 => "H&#46; Takita"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "J Thorac Cardivasc Surg"
                        "fecha" => "1973"
                        "volumen" => "66"
                        "paginaInicial" => "472"
                        "paginaFinal" => "477"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            12 => array:3 [
              "identificador" => "bib0065"
              "etiqueta" => "13&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The survival of the patients with inoperable lung cancer&#58; a large sale randomized study of radiation therapy versus placebo"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:1 [
                            0 => "B&#46; Roswit"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1148/90.4.688"
                      "Revista" => array:6 [
                        "tituloSerie" => "Radiology"
                        "fecha" => "1968"
                        "volumen" => "90"
                        "paginaInicial" => "688"
                        "paginaFinal" => "697"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/4170866"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            13 => array:3 [
              "identificador" => "bib0070"
              "etiqueta" => "14&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Alkylating agents in bronchogenic carcinoma"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:1 [
                            0 => "R&#46;A&#46; Green"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Am J Med"
                        "fecha" => "1969"
                        "volumen" => "46"
                        "paginaInicial" => "516"
                        "paginaFinal" => "524"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/5791000"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            14 => array:3 [
              "identificador" => "bib0075"
              "etiqueta" => "15&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Combined modality therapy for small cell carcinoma of the lung&#46; Proceedings of first world conference&#44; International Association for the study of the lung cancer&#46;"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:1 [
                            0 => "J&#46;D&#46; Bitran"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:3 [
                        "tituloSerie" => "Hilton Head Sc"
                        "fecha" => "1978"
                        "volumen" => "101&#46;"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            15 => array:3 [
              "identificador" => "bib0080"
              "etiqueta" => "16&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Prognostic factors in small cell carcinoma of the lung&#46; A cancer and leukemia goup B&#46; study"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "L&#46; Meurer"
                            1 => "T&#46; Pajak"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Cancer Treat Rep"
                        "fecha" => "1981"
                        "volumen" => "65"
                        "paginaInicial" => "761"
                        "paginaFinal" => "774"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            16 => array:3 [
              "identificador" => "bib0085"
              "etiqueta" => "17&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Small cell carcinoma of the lung&#58; staging paraneoplastic syndromes&#44; treatment and survival"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:1 [
                            0 => "R&#46; Eagan"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:4 [
                        "tituloSerie" => "Cancer"
                        "fecha" => "1974"
                        "volumen" => "33"
                        "paginaInicial" => "529"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            17 => array:3 [
              "identificador" => "bib0090"
              "etiqueta" => "18&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Endocrine function in small cell indiferentiated carcinoma of the lung"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "P&#46; Bondy"
                            1 => "E&#46; Gilby"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Cancer"
                        "fecha" => "1982"
                        "volumen" => "50"
                        "paginaInicial" => "2147"
                        "paginaFinal" => "2153"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/6290025"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            18 => array:3 [
              "identificador" => "bib0095"
              "etiqueta" => "19&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Lung cancer&#44; clinical trial of radiotherapy alone versus radiotherapy plus ciclofosfamyd"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:1 [
                            0 => "D&#46; Bersagel"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Cancer"
                        "fecha" => "1972"
                        "volumen" => "30"
                        "paginaInicial" => "620"
                        "paginaFinal" => "621"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            19 => array:3 [
              "identificador" => "bib0100"
              "etiqueta" => "20&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Carcinoma de c&#233;lulas peque&#241;as de pulm&#243;n&#58; subclasificaci&#243;n histol&#243;gica"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:1 [
                            0 => "M&#46;G&#46; Pallotta"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Libro" => array:2 [
                        "titulo" => "VI Congreso Argentino de Oncolog&#237;a Cl&#237;nica y VI Jornadas Rioplatenses de Oncolog&#237;a Cl&#237;nica&#46; Sept"
                        "fecha" => "1983"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            20 => array:3 [
              "identificador" => "bib0105"
              "etiqueta" => "21&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Laboratory parameters as an alternative to performance status in prognostic stratification of patients with small cell lung cancer"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:1 [
                            0 => "A&#46; Cohen"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Cancer Treat Rep"
                        "fecha" => "1981"
                        "volumen" => "65"
                        "paginaInicial" => "187"
                        "paginaFinal" => "195"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/6263468"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            21 => array:3 [
              "identificador" => "bib0110"
              "etiqueta" => "22&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Combination chemotherapy and radiation therapy for small cell carcinoma"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:1 [
                            0 => "P&#46;Y&#46; Holoye"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "JAMA"
                        "fecha" => "1977"
                        "volumen" => "237"
                        "paginaInicial" => "1221"
                        "paginaFinal" => "1224"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/190427"
                            "web" => "Medline"
                          ]
                        ]
                        "itemHostRev" => array:3 [
                          "pii" => "S1935861X14001661"
                          "estado" => "S300"
                          "issn" => "1935861X"
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            22 => array:3 [
              "identificador" => "bib0115"
              "etiqueta" => "23&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Should initial treatment of small cell carcinoma include systemic chemotherapy and brain irradiations"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "H&#46; Hansen"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Cancer Chemother Rep"
                        "fecha" => "1973"
                        "volumen" => "4"
                        "paginaInicial" => "239"
                        "paginaFinal" => "241"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            23 => array:3 [
              "identificador" => "bib0120"
              "etiqueta" => "24&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Small cell carcinoma of the lung&#46; Combined chemotherapy and radiation&#46; A Southwest oncology group study"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:1 [
                            0 => "R&#46; Livengton"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Ann Intern Med"
                        "fecha" => "1978"
                        "volumen" => "88"
                        "paginaInicial" => "194"
                        "paginaFinal" => "199"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/204239"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            24 => array:3 [
              "identificador" => "bib0125"
              "etiqueta" => "25&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Role of prophylactic cranial irradiation in prevention of central nervous System metastases in small cell lung cancer"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:1 [
                            0 => "S&#46; Rosen"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Am J Med"
                        "fecha" => "1983"
                        "volumen" => "74"
                        "paginaInicial" => "615"
                        "paginaFinal" => "624"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/6301274"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            25 => array:3 [
              "identificador" => "bib0130"
              "etiqueta" => "26&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Small cell carcinoma of the lung&#58; therapeutic management"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "R&#46; Weiss"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Ann Intern Med"
                        "fecha" => "1978"
                        "volumen" => "88"
                        "paginaInicial" => "522"
                        "paginaFinal" => "531"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/205153"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            26 => array:3 [
              "identificador" => "bib0135"
              "etiqueta" => "27&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Small cell carcinoma lung cancer&#58; progress and perspectives"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:1 [
                            0 => "A&#46; Greco"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Semin Oncol"
                        "fecha" => "1978"
                        "volumen" => "5"
                        "paginaInicial" => "323"
                        "paginaFinal" => "335"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/211644"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            27 => array:3 [
              "identificador" => "bib0140"
              "etiqueta" => "28&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Lung cancer"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "O&#46; Selawry"
                            1 => "H&#46; Hansen"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "LibroEditado" => array:4 [
                        "titulo" => "Cancer Medicine"
                        "paginaInicial" => "1709"
                        "paginaFinal" => "1710"
                        "serieFecha" => "1982"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            28 => array:3 [
              "identificador" => "bib0145"
              "etiqueta" => "29&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Lung cancer"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:1 [
                            0 => "J&#46;A&#46; Minna"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "LibroEditado" => array:4 [
                        "titulo" => "Cancer&#46; Principles and practice of oncology"
                        "paginaInicial" => "428"
                        "paginaFinal" => "462"
                        "serieFecha" => "1982"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            29 => array:3 [
              "identificador" => "bib0150"
              "etiqueta" => "30&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Patterns of failure in small cell carcinoma of the lung"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:1 [
                            0 => "L&#46; Chak"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "Cancer"
                        "fecha" => "1982"
                        "volumen" => "50"
                        "paginaInicial" => "1857"
                        "paginaFinal" => "1863"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/6288227"
                            "web" => "Medline"
                          ]
                        ]
                        "itemHostRev" => array:3 [
                          "pii" => "S0967586811004449"
                          "estado" => "S300"
                          "issn" => "09675868"
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            30 => array:3 [
              "identificador" => "bib0155"
              "etiqueta" => "31&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Erytroleukemia and other hematologic complications of intensive therapy in long term survivors of small cell lung cancer"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:1 [
                            0 => "E&#46; Bradley"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Cancer"
                        "fecha" => "1982"
                        "volumen" => "49"
                        "paginaInicial" => "221"
                        "paginaFinal" => "223"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/6274504"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "es"
  "url" => "/03002896/0000002100000005/v1_201509151022/S0300289615321098/v1_201509151022/es/main.assets"
  "Apartado" => array:4 [
    "identificador" => "9277"
    "tipo" => "SECCION"
    "en" => array:2 [
      "titulo" => "Originales"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "en"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/03002896/0000002100000005/v1_201509151022/S0300289615321098/v1_201509151022/es/main.pdf?idApp=UINPBA00003Z&text.app=https://archbronconeumol.org/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289615321098?idApp=UINPBA00003Z"
]