Estudio de la respuesta del centro respiratorio en personas normales mediante la inhalacion de concentraciones progresivamente crecientes de co2 en el aire inspirado
Respiratory center response to inhalation of progressively increasing concentrations of CO2 in normal individuals
J. Naranjo orellana, M. Caraballo avila, E. Rodriguez becerra, J. Castillo gomez
Sección de Fisiopatología. Servicio de Neumología. Hospital General. Sevilla
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Leon jimenez, F. Rodriguez panadero, A. Cantos de la casa, J.J. Del rey perez, J. Lopez mejias" "autores" => array:5 [ 0 => array:2 [ "nombre" => "A." "apellidos" => "Leon jimenez" ] 1 => array:2 [ "nombre" => "F." "apellidos" => "Rodriguez panadero" ] 2 => array:2 [ "nombre" => "A." "apellidos" => "Cantos de la casa" ] 3 => array:2 [ "nombre" => "J.J." "apellidos" => "Del rey perez" ] 4 => array:2 [ "nombre" => "J." "apellidos" => "Lopez mejias" ] ] ] ] ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289615320354?idApp=UINPBA00003Z" "url" => "/03002896/0000002200000004/v1_201509151036/S0300289615320354/v1_201509151036/es/main.assets" ] "es" => array:13 [ "idiomaDefecto" => true "titulo" => "Estudio de la respuesta del centro respiratorio en personas normales mediante la inhalacion de concentraciones progresivamente crecientes de co<span class="elsevierStyleInf">2</span> en el aire inspirado" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "166" "paginaFinal" => "172" ] ] "autores" => array:1 [ 0 => array:3 [ "autoresLista" => "J. Naranjo orellana, M. Caraballo avila, E. Rodriguez becerra, J. Castillo gomez" "autores" => array:4 [ 0 => array:2 [ "nombre" => "J." "apellidos" => "Naranjo orellana" ] 1 => array:2 [ "nombre" => "M." "apellidos" => "Caraballo avila" ] 2 => array:2 [ "nombre" => "E." "apellidos" => "Rodriguez becerra" ] 3 => array:2 [ "nombre" => "J." "apellidos" => "Castillo gomez" ] ] "afiliaciones" => array:1 [ 0 => array:2 [ "entidad" => "Sección de Fisiopatología. Servicio de Neumología. Hospital General. Sevilla" "identificador" => "aff0005" ] ] ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Respiratory center response to inhalation of progressively increasing concentrations of CO<span class="elsevierStyleInf">2</span> in normal individuals" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "1985-12-16" "fechaAceptado" => "1986-04-09" "tieneResumen" => true "resumen" => array:2 [ "es" => array:1 [ "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">En este trabajo se analiza la respuesta de 15 sujetos normales en términos de ventilación, cambios del patrón respiratorio y P<span class="elsevierStyleInf">0,1</span> ante la estimulación con concentraciones progresivamente crecientes de CO<span class="elsevierStyleInf">2</span> en estado estable entre el 1 y 4%, encontrando dos fases en la respuesta: una primera hasta el 3% en la que sólo se observa un aumento progresivo del volumen minuto a expensas del volumen circulante, y una segunda fase, del 3 al 4%, en la que encontramos un aumento muy superior de V<span class="elsevierStyleInf">E</span> y V<span class="elsevierStyleInf">T</span> junto a un alargamiento del tiempo inspiratorio sin que se observe ningún cambio en la duración del ciclo (T<span class="elsevierStyleInf">tot</span>) ni, por tanto, en la frecuencia. De esta forma podemos afirmar que se puede detectar respuesta al CO<span class="elsevierStyleInf">2</span> ya con concentraciones inspiratorias muy bajas y que dicha respuesta parece seguir una secuencia de hechos perfectamente establecida en la que el aumento de la frecuencia respiratoria ocuparía el último lugar, al menos en personas normales.</p></span>" ] "en" => array:1 [ "resumen" => "<span id="abst0010" class="elsevierStyleSection elsevierViewall"><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">The results are reported for a study in which the response of 15 individuals with normal ventilation were analyzed for changes in the respiratory pattern and P<span class="elsevierStyleInf">0,1</span> after stimulation with progressively increasing concentrations of CO<span class="elsevierStyleInf">2</span> stabilized between 1 and 4%. Two phases were found in the responses: a first one with up to 3% in which there was only a Progressive increase in minue volume over the circulating volume and a second phase at from 3 to 4% in which there was an considerable increase in V<span class="elsevierStyleInf">E</span> and V<span class="elsevierStyleInf">T</span> together with lengthening of the inspiratory time without any change seen in the length of the cycle (T<span class="elsevierStyleInf">tot</span>) and thus in the frequency. These results indicate that a response to CO<span class="elsevierStyleInf">2</span>, may be detected even at very low inspiratory concentrations and that this response appears to follow a perfectly defined sequence in which the increase in respiratory frequency occurs in last place, at least in the case of normal individuals.</p></span>" ] ] "bibliografia" => array:2 [ "titulo" => "Bibliografia" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:26 [ 0 => array:3 [ "identificador" => "bib0005" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Neural regulation of respiration (State of the art)" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "R.A. Mitchcl" 1 => "A.J. 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| Year/Month | Html | Total | |
|---|---|---|---|
| 2024 November | 4 | 3 | 7 |
| 2024 October | 28 | 18 | 46 |
| 2024 September | 24 | 26 | 50 |
| 2024 August | 46 | 39 | 85 |
| 2024 July | 32 | 32 | 64 |
| 2024 June | 45 | 21 | 66 |
| 2024 May | 35 | 31 | 66 |
| 2024 April | 31 | 15 | 46 |
| 2024 March | 34 | 23 | 57 |
| 2024 February | 33 | 50 | 83 |
| 2024 January | 0 | 4 | 4 |
| 2023 December | 0 | 5 | 5 |
| 2023 November | 0 | 5 | 5 |
| 2023 October | 3 | 13 | 16 |
| 2023 September | 4 | 23 | 27 |
| 2023 August | 7 | 25 | 32 |
| 2023 July | 2 | 17 | 19 |
| 2023 April | 0 | 1 | 1 |
| 2023 March | 2 | 4 | 6 |
| 2023 February | 22 | 17 | 39 |
| 2023 January | 26 | 27 | 53 |
| 2022 December | 28 | 28 | 56 |
| 2022 November | 32 | 16 | 48 |
| 2022 October | 20 | 36 | 56 |
| 2022 September | 18 | 33 | 51 |
| 2022 August | 25 | 33 | 58 |
| 2022 July | 21 | 40 | 61 |
| 2022 June | 18 | 37 | 55 |
| 2022 May | 24 | 18 | 42 |
| 2022 April | 25 | 31 | 56 |
| 2022 March | 28 | 23 | 51 |
| 2022 February | 27 | 39 | 66 |
| 2022 January | 24 | 24 | 48 |
| 2021 December | 10 | 32 | 42 |
| 2021 November | 16 | 22 | 38 |
| 2021 October | 15 | 31 | 46 |
| 2021 September | 19 | 21 | 40 |
| 2021 August | 16 | 27 | 43 |
| 2021 July | 15 | 22 | 37 |
| 2021 June | 14 | 19 | 33 |
| 2021 May | 9 | 19 | 28 |
| 2021 April | 23 | 39 | 62 |
| 2021 March | 38 | 8 | 46 |
| 2021 February | 40 | 7 | 47 |
| 2021 January | 15 | 5 | 20 |
| 2020 December | 20 | 6 | 26 |
| 2020 November | 8 | 6 | 14 |
| 2020 October | 8 | 5 | 13 |
| 2020 September | 9 | 9 | 18 |
| 2020 August | 11 | 10 | 21 |
| 2020 July | 19 | 9 | 28 |
| 2020 June | 7 | 13 | 20 |
| 2020 May | 14 | 21 | 35 |
| 2020 April | 17 | 10 | 27 |
| 2020 March | 12 | 17 | 29 |
| 2020 February | 25 | 20 | 45 |
| 2020 January | 34 | 31 | 65 |
| 2019 December | 25 | 24 | 49 |
| 2019 November | 18 | 8 | 26 |
| 2019 October | 4 | 7 | 11 |
| 2019 September | 3 | 14 | 17 |
| 2019 August | 8 | 6 | 14 |
| 2019 July | 5 | 22 | 27 |
| 2019 June | 8 | 23 | 31 |
| 2019 May | 12 | 27 | 39 |
| 2019 April | 18 | 34 | 52 |
| 2019 March | 7 | 22 | 29 |
| 2019 February | 8 | 9 | 17 |
| 2019 January | 4 | 4 | 8 |
| 2018 December | 7 | 13 | 20 |
| 2018 November | 13 | 10 | 23 |
| 2018 October | 22 | 9 | 31 |
| 2018 September | 9 | 9 | 18 |
| 2018 May | 4 | 2 | 6 |
| 2018 April | 5 | 4 | 9 |
| 2018 March | 10 | 9 | 19 |
| 2018 February | 7 | 12 | 19 |
| 2018 January | 4 | 1 | 5 |
| 2017 December | 9 | 12 | 21 |
| 2017 November | 6 | 7 | 13 |
| 2017 October | 11 | 8 | 19 |
| 2017 September | 4 | 3 | 7 |
| 2017 August | 9 | 9 | 18 |
| 2017 July | 4 | 9 | 13 |
| 2017 June | 10 | 12 | 22 |
| 2017 May | 13 | 13 | 26 |
| 2017 April | 9 | 6 | 15 |
| 2017 March | 3 | 6 | 9 |
| 2017 February | 4 | 8 | 12 |
| 2017 January | 3 | 5 | 8 |
| 2016 December | 5 | 6 | 11 |
| 2016 November | 17 | 10 | 27 |
| 2016 October | 20 | 16 | 36 |
| 2016 September | 16 | 9 | 25 |
| 2016 August | 19 | 10 | 29 |
| 2016 July | 26 | 5 | 31 |
| 2016 June | 15 | 6 | 21 |
| 2016 May | 17 | 2 | 19 |
| 2016 April | 7 | 0 | 7 |
| 2016 March | 8 | 1 | 9 |
| 2016 February | 8 | 1 | 9 |
| 2016 January | 13 | 5 | 18 |
| 2015 December | 19 | 15 | 34 |
| 2015 November | 23 | 6 | 29 |
| 2015 October | 8 | 2 | 10 |
| 2015 September | 1 | 0 | 1 |
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