Tratamiento con quimio-radioterapia en el carcinoma indiferenciado de celulas pequeñas del pulmon. Estudio prospectivo en 32 pacientes
Chemotherapy with radiotherapy in the treatment of indifferentiated small cell lung carcinoma. Prospective study on 32 patients
L. Borderias Clau, J. Teran Santos, R. Agüero Balbin, F. Zurbano Goñi, J. Duran Cantolla, J. Barrio Soto, A. Jimenez Gomez
Servicio de Neumología. Hospital Nacional Marqués de Valdecilla. Santander
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"apellidos" => "Lamata Hernandez" ] 5 => array:2 [ "nombre" => "A." "apellidos" => "Garcia Cirac" ] 6 => array:2 [ "nombre" => "M." "apellidos" => "Gonzalez Gonzalez" ] ] ] ] ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289615319906?idApp=UINPBA00003Z" "url" => "/03002896/0000002300000001/v1_201509151049/S0300289615319906/v1_201509151049/es/main.assets" ] "es" => array:13 [ "idiomaDefecto" => true "titulo" => "Tratamiento con quimio-radioterapia en el carcinoma indiferenciado de celulas pequeñas del pulmon. Estudio prospectivo en 32 pacientes" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "10" "paginaFinal" => "14" ] ] "autores" => array:1 [ 0 => array:3 [ "autoresLista" => "L. Borderias Clau, J. Teran Santos, R. Agüero Balbin, F. Zurbano Goñi, J. Duran Cantolla, J. Barrio Soto, A. Jimenez Gomez" "autores" => array:7 [ 0 => array:2 [ "nombre" => "L." "apellidos" => "Borderias Clau" ] 1 => array:2 [ "nombre" => "J." "apellidos" => "Teran Santos" ] 2 => array:2 [ "nombre" => "R." "apellidos" => "Agüero Balbin" ] 3 => array:2 [ "nombre" => "F." "apellidos" => "Zurbano Goñi" ] 4 => array:2 [ "nombre" => "J." "apellidos" => "Duran Cantolla" ] 5 => array:2 [ "nombre" => "J." "apellidos" => "Barrio Soto" ] 6 => array:2 [ "nombre" => "A." "apellidos" => "Jimenez Gomez" ] ] "afiliaciones" => array:1 [ 0 => array:2 [ "entidad" => "Servicio de Neumología. Hospital Nacional Marqués de Valdecilla. Santander" "identificador" => "aff0005" ] ] ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Chemotherapy with radiotherapy in the treatment of indifferentiated small cell lung carcinoma. Prospective study on 32 patients" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "1986-03-20" "fechaAceptado" => "1986-07-03" "tieneResumen" => true "resumen" => array:2 [ "es" => array:1 [ "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Los autores realizan un estudio prospectivo sobre 32 pacientes afectos de carcinoma pulmonar de células pequeñas (CPCP), tratados con un régimen mixto de poliquimio-radioterapia (ciclofosfamida, adriamicina, VP-16, vincristina).</p><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Los factores pronósticos fueron el índice de Karnofsky y la extensión tumoral. La supervivencia media fue de 56 semanas para el grupo de enfermedad localizada (EL) y de 34 semanas para los de enfermedad extendida (EE). El porcentaje de respuestas completas en pacientes con EL fue significativamente mayor que el de los que presentaban EE. En la serie hubo tres pacientes con larga supervivencia. Debido a las dosis moderadas empleadas en el protocolo, los efectos secundarios no fueron importantes y no se produjo ninguna muerte tóxica.</p></span>" ] "en" => array:1 [ "resumen" => "<span id="abst0010" class="elsevierStyleSection elsevierViewall"><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">The authors conducted a prospective study on 32 patients with small cell lung carcinoma (CPCP) treated with a mixed regimen of polichemotherapy (cyclophosphamide, adriamycin, VP-1, vincristine) and radiotherapy.</p><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">The pronostic factors were the Karnofsky index and the spreading of the tumour. The mean survival time was 56 weeks for the group with local disease (EL) and 34 weeks for the patients with disseminated disease (EE). The percentage of complete responsos among EL patients was significatively greater than in the EE group of patients. Three patients of this series showed a long survival. Due to the moderate dosage used in the protocol, side effects were mild and no death was attributable to toxic drug effects.</p></span>" ] ] "bibliografia" => array:2 [ "titulo" => "Bibliografia" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:22 [ 0 => array:3 [ "identificador" => "bib0005" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Cáncer de pulmón. En: Cáncer principio y práctica de oncología" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:3 [ 0 => "J.D. Minna" 1 => "G.A. Higgins" 2 => "E.J. Glastein" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Libro" => array:5 [ "fecha" => "1985" "paginaInicial" => "371" "paginaFinal" => "445" "editorial" => "Ed Salvat" "editorialLocalizacion" => "De Vita V. Barcelona" ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib0010" "etiqueta" => "2." 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| Year/Month | Html | Total | |
|---|---|---|---|
| 2024 November | 5 | 1 | 6 |
| 2024 October | 35 | 18 | 53 |
| 2024 September | 32 | 18 | 50 |
| 2024 August | 55 | 26 | 81 |
| 2024 July | 37 | 26 | 63 |
| 2024 June | 40 | 16 | 56 |
| 2024 May | 35 | 23 | 58 |
| 2024 April | 31 | 17 | 48 |
| 2024 March | 28 | 29 | 57 |
| 2024 February | 33 | 32 | 65 |
| 2024 January | 0 | 4 | 4 |
| 2023 November | 0 | 4 | 4 |
| 2023 October | 0 | 7 | 7 |
| 2023 September | 0 | 9 | 9 |
| 2023 August | 0 | 10 | 10 |
| 2023 July | 0 | 17 | 17 |
| 2023 June | 0 | 1 | 1 |
| 2023 March | 3 | 3 | 6 |
| 2023 February | 52 | 19 | 71 |
| 2023 January | 32 | 49 | 81 |
| 2022 December | 25 | 25 | 50 |
| 2022 November | 35 | 22 | 57 |
| 2022 October | 23 | 35 | 58 |
| 2022 September | 22 | 22 | 44 |
| 2022 August | 25 | 40 | 65 |
| 2022 July | 22 | 35 | 57 |
| 2022 June | 19 | 37 | 56 |
| 2022 May | 27 | 18 | 45 |
| 2022 April | 35 | 33 | 68 |
| 2022 March | 33 | 32 | 65 |
| 2022 February | 51 | 19 | 70 |
| 2022 January | 32 | 20 | 52 |
| 2021 December | 31 | 32 | 63 |
| 2021 November | 32 | 36 | 68 |
| 2021 October | 34 | 30 | 64 |
| 2021 September | 30 | 34 | 64 |
| 2021 August | 45 | 34 | 79 |
| 2021 July | 39 | 24 | 63 |
| 2021 June | 35 | 29 | 64 |
| 2021 May | 35 | 26 | 61 |
| 2021 April | 50 | 37 | 87 |
| 2021 March | 65 | 12 | 77 |
| 2021 February | 70 | 19 | 89 |
| 2021 January | 50 | 8 | 58 |
| 2020 December | 43 | 21 | 64 |
| 2020 November | 26 | 11 | 37 |
| 2020 October | 38 | 10 | 48 |
| 2020 September | 33 | 10 | 43 |
| 2020 August | 34 | 11 | 45 |
| 2020 July | 31 | 14 | 45 |
| 2020 June | 29 | 19 | 48 |
| 2020 May | 36 | 16 | 52 |
| 2020 April | 40 | 11 | 51 |
| 2020 March | 28 | 18 | 46 |
| 2020 February | 39 | 17 | 56 |
| 2020 January | 47 | 16 | 63 |
| 2019 December | 54 | 25 | 79 |
| 2019 November | 27 | 16 | 43 |
| 2019 October | 24 | 14 | 38 |
| 2019 September | 16 | 20 | 36 |
| 2019 August | 21 | 8 | 29 |
| 2019 July | 29 | 28 | 57 |
| 2019 June | 27 | 27 | 54 |
| 2019 May | 61 | 30 | 91 |
| 2019 April | 37 | 47 | 84 |
| 2019 March | 16 | 32 | 48 |
| 2019 February | 12 | 4 | 16 |
| 2019 January | 16 | 4 | 20 |
| 2018 December | 9 | 15 | 24 |
| 2018 November | 20 | 22 | 42 |
| 2018 October | 14 | 20 | 34 |
| 2018 September | 18 | 10 | 28 |
| 2018 May | 8 | 1 | 9 |
| 2018 April | 4 | 4 | 8 |
| 2018 March | 6 | 7 | 13 |
| 2018 February | 9 | 7 | 16 |
| 2018 January | 5 | 5 | 10 |
| 2017 December | 12 | 13 | 25 |
| 2017 November | 8 | 10 | 18 |
| 2017 October | 7 | 8 | 15 |
| 2017 September | 6 | 18 | 24 |
| 2017 August | 13 | 11 | 24 |
| 2017 July | 6 | 14 | 20 |
| 2017 June | 9 | 18 | 27 |
| 2017 May | 11 | 16 | 27 |
| 2017 April | 10 | 10 | 20 |
| 2017 March | 6 | 10 | 16 |
| 2017 February | 9 | 10 | 19 |
| 2017 January | 7 | 6 | 13 |
| 2016 December | 3 | 16 | 19 |
| 2016 November | 10 | 19 | 29 |
| 2016 October | 11 | 18 | 29 |
| 2016 September | 11 | 13 | 24 |
| 2016 August | 17 | 6 | 23 |
| 2016 July | 22 | 8 | 30 |
| 2016 June | 12 | 8 | 20 |
| 2016 May | 19 | 9 | 28 |
| 2016 April | 21 | 0 | 21 |
| 2016 March | 6 | 0 | 6 |
| 2016 February | 5 | 0 | 5 |
| 2016 January | 25 | 11 | 36 |
| 2015 December | 23 | 14 | 37 |
| 2015 November | 31 | 7 | 38 |
| 2015 October | 5 | 1 | 6 |
| 2015 September | 1 | 0 | 1 |
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