Carcinoma broncogenico en pacientes menores de 50 años. Presentacion de 50 casos y revision de la literatura
Bronchogenic carcinoma in patients younger than 50 years of age. A report of 50 cases and a review of the literature
J.A. Caminero Luna
Hospital de Enfermedades del Tórax El Sabinal. Las Palmas de Gran Canaria
Read
3145
Timeswas read the article
1473
Total PDF
1672
Total HTML
Share statistics
array:23 [ "pii" => "S0300289615318305" "issn" => "03002896" "doi" => "10.1016/S0300-2896(15)31830-5" "estado" => "S300" "fechaPublicacion" => "1988-07-01" "aid" => "71900" "copyright" => "Sociedad Española de Neumología y Cirugía Torácica" "copyrightAnyo" => "1988" "documento" => "article" "crossmark" => 0 "subdocumento" => "fla" "cita" => "Arch Bronconeumol. 1988;24:169-73" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 1084 "formatos" => array:3 [ "EPUB" => 54 "HTML" => 581 "PDF" => 449 ] ] "itemSiguiente" => array:18 [ "pii" => "S0300289615318317" "issn" => "03002896" "doi" => "10.1016/S0300-2896(15)31831-7" "estado" => "S300" "fechaPublicacion" => "1988-07-01" "aid" => "71901" "copyright" => "Sociedad Española de Neumología y Cirugía Torácica" "documento" => "article" "crossmark" => 0 "subdocumento" => "fla" "cita" => "Arch Bronconeumol. 1988;24:174-9" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 3129 "formatos" => array:3 [ "EPUB" => 47 "HTML" => 609 "PDF" => 2473 ] ] "es" => array:7 [ "idiomaDefecto" => true "titulo" => "Resonancia magnetica en el estudio del metabolismo celular" "tienePdf" => "es" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "174" "paginaFinal" => "179" ] ] "contienePdf" => array:1 [ "es" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "G. Gutiérrez, A.L. Acero" "autores" => array:2 [ 0 => array:2 [ "nombre" => "G." "apellidos" => "Gutiérrez" ] 1 => array:2 [ "nombre" => "A.L." "apellidos" => "Acero" ] ] ] ] ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289615318317?idApp=UINPBA00003Z" "url" => "/03002896/0000002400000004/v1_201509151100/S0300289615318317/v1_201509151100/es/main.assets" ] "itemAnterior" => array:18 [ "pii" => "S0300289615318299" "issn" => "03002896" "doi" => "10.1016/S0300-2896(15)31829-9" "estado" => "S300" "fechaPublicacion" => "1988-07-01" "aid" => "71899" "copyright" => "Sociedad Española de Neumología y Cirugía Torácica" "documento" => "article" "crossmark" => 0 "subdocumento" => "fla" "cita" => "Arch Bronconeumol. 1988;24:165-8" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 1042 "formatos" => array:3 [ "EPUB" => 47 "HTML" => 528 "PDF" => 467 ] ] "es" => array:10 [ "idiomaDefecto" => true "titulo" => "La fluorescencia como guia de la toma de biopsias pleurales trans-toracoscopicas" "tienePdf" => "es" "tieneTextoCompleto" => 0 "tieneResumen" => array:2 [ 0 => "es" 1 => "en" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "165" "paginaFinal" => "168" ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "The fluorescence as a guide for obtaining transthoracoscopic pleural biopsies" ] ] "contieneResumen" => array:2 [ "es" => true "en" => true ] "contienePdf" => array:1 [ "es" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "F. Sebastián Quetglás, D. Luna Sabaté, F. Romany Díez, N. Múgica Atorrasagasti, P. Teller Justes, R. Luque Díez, A. Celaya Pérez" "autores" => array:7 [ 0 => array:2 [ "nombre" => "F." "apellidos" => "Sebastián Quetglás" ] 1 => array:2 [ "nombre" => "D." "apellidos" => "Luna Sabaté" ] 2 => array:2 [ "nombre" => "F." "apellidos" => "Romany Díez" ] 3 => array:2 [ "nombre" => "N." "apellidos" => "Múgica Atorrasagasti" ] 4 => array:2 [ "nombre" => "P." "apellidos" => "Teller Justes" ] 5 => array:2 [ "nombre" => "R." "apellidos" => "Luque Díez" ] 6 => array:2 [ "nombre" => "A." "apellidos" => "Celaya Pérez" ] ] ] ] ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289615318299?idApp=UINPBA00003Z" "url" => "/03002896/0000002400000004/v1_201509151100/S0300289615318299/v1_201509151100/es/main.assets" ] "es" => array:11 [ "idiomaDefecto" => true "titulo" => "Carcinoma broncogenico en pacientes menores de 50 años. Presentacion de 50 casos y revision de la literatura" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "169" "paginaFinal" => "173" ] ] "autores" => array:1 [ 0 => array:3 [ "autoresLista" => "J.A. Caminero Luna" "autores" => array:1 [ 0 => array:2 [ "nombre" => "J.A." "apellidos" => "Caminero Luna" ] ] "afiliaciones" => array:1 [ 0 => array:2 [ "entidad" => "Hospital de Enfermedades del Tórax El Sabinal. Las Palmas de Gran Canaria" "identificador" => "aff0005" ] ] ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Bronchogenic carcinoma in patients younger than 50 years of age. A report of 50 cases and a review of the literature" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "tieneResumen" => true "resumen" => array:2 [ "es" => array:1 [ "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Se presenta una revisión completa de 50 pacientes menores de 50 años con diagnóstico anatomopatológico de carcinoma broncogénico, vistos en nuestro centro durante seis años. Se presentan los datos de nuestros pacientes y se hace una confrontación detallada con el resto de las series que sobre el tema se han encontrado en la bibliografía. Representan el 7,5% de todos los carcinomas broncogénicos de nuestro centro y de este tiempo, con una proporción mujer:varón de 1:24. El 92% eran fumadores. La localización del tumor fue central en 70,8% y ligeramente más frecuente en el pulmón derecho y en campos superiores. El 48% fueron ca. epidermoides, el 12% adenocarcinomas, el 30% ca. indiferenciados de células pequeñas y el 10% otros. Los síntomas más referidos fueron tos y dolor torácico. El rendimiento total de la broncofibroscopia fue del 72,9%. El estadio evolutivo era muy avanzado: (IIIa: 9%, IIIb: 40%, <span class="elsevierStyleSmallCaps">IV</span>: 31%). La cirugía se realizó en el 32% de los pacientes. La supervivencia media de la serie fue de 3,8 meses, con una supervivencia a 3 años del 4% y a 5 años, del 0%. La mayor supervivencia media correspondió al ca. epidermoide (7 meses) y al tratamiento quimioterápico (7 meses).</p></span>" ] "en" => array:1 [ "resumen" => "<span id="abst0010" class="elsevierStyleSection elsevierViewall"><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">We present a complete review of 50 patients younger than 50 years of age with anatomopathologically proven bronchogenic carcinoma, who were attended at our Service during a six year period. We present the findings and an exhaustive comparison with the other series in the relevant literature. They accounted for the 7.5% of all the bronchogenic carcinoma diagnosed at our centre, with a ratio women: men of 1:24. Ninety two percent were smokers. The tumor was centrally localized in 70.8% and slightly more frequent in right lung and upper fields. Forty eight percent were epidermoid, 12% adenocarcinoma, 30% oat cell carcinoma and 10% were other forms. The most frequent symptoms were cough and chest pain. The overall yielding of the flbrobronchoscopic study was 72.9%. The evolutive stage was very advanced (IIIa: 9%, IIIb: 40% <span class="elsevierStyleSmallCaps">IV</span>: 31%). Thirty two percent of patients underwent surgical treatment. The mean survival was 3.8 months; the 3 years survival was 4% and 5 years survival was 0%. The highest mean survival fitted into epidermoid carcinoma (7 months) and into chemotherapy (7 months).</p></span>" ] ] "bibliografia" => array:2 [ "titulo" => "Bibliografía" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:34 [ 0 => array:3 [ "identificador" => "bib0005" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Análisis de 163 casos de cáncer primitivo de pulmón" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:3 [ 0 => "A. Agustí Vidal" 1 => "J. Estapé" 2 => "J.J. Grau" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Arch B ronconeumol" "fecha" => "1979" "volumen" => "15" "paginaInicial" => "7" "paginaFinal" => "10" ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib0010" "etiqueta" => "2." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Lung cancer in women" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "D.J.B. Ashley" 1 => "H.D. Davies" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Thorax" "fecha" => "1969" "volumen" => "24" "paginaInicial" => "446" "paginaFinal" => "450" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/5795647" "web" => "Medline" ] ] ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib0015" "etiqueta" => "3." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Cáncer de pulmón Análisis clínico de 122 casos" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "J. Garcés" 1 => "I. Guasch" 2 => "J. Planas" 3 => "J. Broquetas" 4 => "L. Drobnic" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Med Clin" "fecha" => "1982" "volumen" => "79" "paginaInicial" => "441" "paginaFinal" => "444" ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib0020" "etiqueta" => "4." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Carcinoma of the bronchus in young adults" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "K.H. Kwong" 1 => "P.R. Slade" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Br J Dis Ches" "fecha" => "1964" "volumen" => "58" "paginaInicial" => "124" "paginaFinal" => "130" ] ] ] ] ] ] 4 => array:3 [ "identificador" => "bib0025" "etiqueta" => "5." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Cancer of the lung in young men" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "M. Kyriacos" 1 => "B. Webber" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Thorac Cardiovasc Surg" "fecha" => "1974" "volumen" => "67" "paginaInicial" => "634" "paginaFinal" => "648" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/4361990" "web" => "Medline" ] ] ] ] ] ] ] ] 5 => array:3 [ "identificador" => "bib0030" "etiqueta" => "6." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Cáncer de pulmón (I), Epidemiología. Clínica. Radiología" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "J.M. Marín Trigo" 1 => "M. Candel Calderón" 2 => "A. Sebastián Ariño" 3 => "A. Pierna Sauza" 4 => "R. Marco Larrega" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Rev Clin Esp" "fecha" => "1985" "volumen" => "176" "paginaInicial" => "237" "paginaFinal" => "242" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/4001478" "web" => "Medline" ] ] ] ] ] ] ] ] 6 => array:3 [ "identificador" => "bib0035" "etiqueta" => "7." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Neoplasms of the lung. Harrison's Principies of Internal Medicine" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "G.M. Tisi" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Libro" => array:5 [ "edicion" => "Ninth Edition" "fecha" => "1980" "paginaInicial" => "1. 259" "editorial" => "Mc Graw-Hill Book Company" "editorialLocalizacion" => "New York" ] ] ] ] ] ] 7 => array:3 [ "identificador" => "bib0040" "etiqueta" => "8." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Bronchogenic carcinoma in patients younger than 40 years" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "J.H. Pemberton" 1 => "D.M. Nagorney" 2 => "J.C. Gilmore" 3 => "W.F. Taylor" 4 => "P.E. Bernatz" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Ann Thorac Surg" "fecha" => "1983" "volumen" => "36" "paginaInicial" => "509" "paginaFinal" => "515" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/6195979" "web" => "Medline" ] ] ] ] ] ] ] ] 8 => array:3 [ "identificador" => "bib0045" "etiqueta" => "9." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Lung cancer in young persons" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "L. Decaro" 1 => "J.R. Benfield" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Thorac Cardiovasc Surg" "fecha" => "1982" "volumen" => "83" "paginaInicial" => "372" "paginaFinal" => "376" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/6278230" "web" => "Medline" ] ] ] ] ] ] ] ] 9 => array:3 [ "identificador" => "bib0050" "etiqueta" => "10." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Bronchogenic carcinoma in young persons" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "W.J. Hanbyry" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Brit J Cancer" "fecha" => "1958" "volumen" => "12" "paginaInicial" => "202" "paginaFinal" => "206" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/13546518" "web" => "Medline" ] ] ] ] ] ] ] ] 10 => array:3 [ "identificador" => "bib0055" "etiqueta" => "11." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Bronchogenic carcinoma in young people" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "R.H. Hood" 1 => "D.C. Campbell" 2 => "B.N. Dooley" 3 => "J.A. Doling" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Dis Chest" "fecha" => "1965" "volumen" => "48" "paginaInicial" => "469" "paginaFinal" => "470" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/5844577" "web" => "Medline" ] ] ] ] ] ] ] ] 11 => array:3 [ "identificador" => "bib0060" "etiqueta" => "12." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Lung cancer in young adults" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "A. Kennedy" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Br J Dis Chest" "fecha" => "1972" "volumen" => "66" "paginaInicial" => "147" "paginaFinal" => "154" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/4338468" "web" => "Medline" ] ] ] ] ] ] ] ] 12 => array:3 [ "identificador" => "bib0065" "etiqueta" => "13." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Bronchial carcinoma in young adults" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "S.E. Large" 1 => "W.K.C. Morgan" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Brit J Tuberc" "fecha" => "1958" "volumen" => "52" "paginaInicial" => "185" "paginaFinal" => "189" ] ] ] ] ] ] 13 => array:3 [ "identificador" => "bib0070" "etiqueta" => "14." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Lung carcinoma in young adults" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "J.S. Putnam" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "JAMA" "fecha" => "1977" "volumen" => "238" "paginaInicial" => "35" "paginaFinal" => "36" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/194069" "web" => "Medline" ] ] ] ] ] ] ] ] 14 => array:3 [ "identificador" => "bib0075" "etiqueta" => "15." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Bronchogenic carcinoma in young men" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "A. Anderson" 1 => "H. Buechner" 2 => "I. Yager" 3 => "M. Ziskind" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Am J Med" "fecha" => "1954" "volumen" => "16" "paginaInicial" => "404" "paginaFinal" => "415" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/13138611" "web" => "Medline" ] ] ] ] ] ] ] ] 15 => array:3 [ "identificador" => "bib0080" "etiqueta" => "16." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Lung cancer in young patients" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "P.A. Ganz" 1 => "S.E. Vernon" 2 => "D. Preston" 3 => "W. Coulson" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "West J Med" "fecha" => "1980" "volumen" => "133" "paginaInicial" => "373" "paginaFinal" => "378" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7467293" "web" => "Medline" ] ] ] ] ] ] ] ] 16 => array:3 [ "identificador" => "bib0085" "etiqueta" => "17." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Italian lung cancer death rates in young males" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "C. La Vechia" 1 => "S. Franceschi" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/S2215-0366(14)70310-4" "Revista" => array:5 [ "tituloSerie" => "Lancet" "fecha" => "1984" "volumen" => "1" "paginaInicial" => "406" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/26361181" "web" => "Medline" ] ] ] ] ] ] ] ] 17 => array:3 [ "identificador" => "bib0090" "etiqueta" => "18." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Lung cancer in young pacients" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "M.F. Mc Kneally" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Ann Thorac. Surg" "fecha" => "1983" "volumen" => "36" "paginaInicial" => "505" "paginaFinal" => "507" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/6314918" "web" => "Medline" ] ] ] ] ] ] ] ] 18 => array:3 [ "identificador" => "bib0095" "etiqueta" => "19." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Bronchogenic carcinoma in persons under forty years of age" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "H.W. Neuman" 1 => "F.H. Ellis" 2 => "J.R. Mc Donald" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "N Eng J Med" "fecha" => "1956" "volumen" => "254" "paginaInicial" => "502" "paginaFinal" => "507" ] ] ] ] ] ] 19 => array:3 [ "identificador" => "bib0100" "etiqueta" => "20." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Bronchogenic carcinoma in men under 40 years of age" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "L.M. Rivking" 1 => "J.M. Salyer" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Dis Chest" "fecha" => "1958" "volumen" => "34" "paginaInicial" => "521" "paginaFinal" => "524" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/13586149" "web" => "Medline" ] ] ] ] ] ] ] ] 20 => array:3 [ "identificador" => "bib0105" "etiqueta" => "21." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Adenocarcinoma of the lung in Vietnam veterans younger than 35 years" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "L. Schacter" 1 => "E. Crum" 2 => "S. Abboud" 3 => "H. Mendelson" 4 => "T. Spitzer" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:4 [ "tituloSerie" => "JAMA" "fecha" => "1984" "volumen" => "252" "paginaInicial" => "604" ] ] ] ] ] ] 21 => array:3 [ "identificador" => "bib0110" "etiqueta" => "22." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Mortality in relation to smoking; Ten years observations of British Doctor" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "R. Doll" 1 => "A.B. Hill" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Brit Med J" "fecha" => "1964" "volumen" => "1" "paginaInicial" => "1399" "paginaFinal" => "1410" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/445100" "web" => "Medline" ] ] ] ] ] ] ] ] 22 => array:3 [ "identificador" => "bib0115" "etiqueta" => "23." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Consequences of smoking on the health" "autores" => array:1 [ 0 => array:2 [ "colaboracion" => "US., Department of Health, Education, Walfare:Public Health Service" "etal" => false ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:3 [ "tituloSerie" => "Dhew Publication n.° (HSM), 73-8.704" "fecha" => "1973" "volumen" => "1" ] ] ] ] ] ] 23 => array:3 [ "identificador" => "bib0120" "etiqueta" => "24." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Research on causes of lung cancer:case control study of 523 cases of lung cancer" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "H.J. Fu" 1 => "J. Gou" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Can J Public Health" "fecha" => "1984" "volumen" => "75" "paginaInicial" => "161" "paginaFinal" => "165" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/6733657" "web" => "Medline" ] ] ] ] ] ] ] ] 24 => array:3 [ "identificador" => "bib0125" "etiqueta" => "25." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Smoking chronic bronchitis and lung cancer" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "J. Rimington" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Brit Med J" "fecha" => "1971" "volumen" => "2" "paginaInicial" => "373" "paginaFinal" => "375" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/890303" "web" => "Medline" ] ] ] ] ] ] ] ] 25 => array:3 [ "identificador" => "bib0130" "etiqueta" => "26." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Diagnóstico de las enfermedades del Tórax" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "R.G. Fraser" 1 => "J.A.P. Pare" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Libro" => array:4 [ "fecha" => "1973" "paginaInicial" => "698" "editorial" => "Salvat Editores" "editorialLocalizacion" => "Barcelona" ] ] ] ] ] ] 26 => array:3 [ "identificador" => "bib0135" "etiqueta" => "27." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Datos epidemiológicos del carcinoma broncogénico" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "A. López Encuentra" 1 => "J. Martínez González del Río" 2 => "E. Pérez Rodríguez" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Med Clin" "fecha" => "1979" "volumen" => "72" "paginaInicial" => "361" "paginaFinal" => "368" ] ] ] ] ] ] 27 => array:3 [ "identificador" => "bib0140" "etiqueta" => "28." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Carcinoma de pulmón III. Diagnóstico broncoscópico" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:3 [ 0 => "C. Puzo" 1 => "J. Castella" 2 => "D. Nauffal" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Med Clin (Barcel)" "fecha" => "1978" "volumen" => "71" "paginaInicial" => "86" "paginaFinal" => "88" ] ] ] ] ] ] 28 => array:3 [ "identificador" => "bib0145" "etiqueta" => "29." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "El cáncer broncopulmonar en nuestro medio. A propósito de 72 casos" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "J.J. Cruz Hernández" 1 => "J. Del Pino Montes" 2 => "M.S. Vega Cruz" 3 => "J. Piñuel Raigado" 4 => "A. Sánchez Rodríguez" 5 => "J. De Portugal Alvarez" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Rev Clin Esp" "fecha" => "1982" "volumen" => "165" "paginaInicial" => "337" "paginaFinal" => "342" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7134557" "web" => "Medline" ] ] ] ] ] ] ] ] 29 => array:3 [ "identificador" => "bib0150" "etiqueta" => "30." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Cáncer de pulmón (II) Diagnóstico. Clasificación. Tratamiento quirúrgico" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "J.M. Marín Trigo" 1 => "A. Sebastián Ariño" 2 => "J. García Aranda" 3 => "A. Esteve-Mir" 4 => "M. Candel Calderón" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Rev Clin Esp" "fecha" => "1985" "volumen" => "176" "paginaInicial" => "243" "paginaFinal" => "247" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/4001479" "web" => "Medline" ] ] ] ] ] ] ] ] 30 => array:3 [ "identificador" => "bib0155" "etiqueta" => "31." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Diagnóstico de extensión y estrategia terapéutica en el cáncer de pulmón Tratado de Medicina Práctica" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "J. Estapé Rodríguez" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Medicine (ed. esp)" "fecha" => "1980" "volumen" => "44" "paginaInicial" => "27" "paginaFinal" => "37" ] ] ] ] ] ] 31 => array:3 [ "identificador" => "bib0160" "etiqueta" => "32." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Carcinoma de pulmón en tratado de patología quirúrgica" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "D.C. Sabiston Jr." ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Libro" => array:5 [ "edicion" => "11.a Edición" "fecha" => "1981" "paginaInicial" => "2091" "editorial" => "Nueva Editorial Interamericana" "editorialLocalizacion" => "México" ] ] ] ] ] ] 32 => array:3 [ "identificador" => "bib0165" "etiqueta" => "33." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Survival in lung cancer. An analysis of the effects of age sex, resectability and histopathologic type" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "T.H. Rossing" 1 => "R.G. Rossing" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1164/arrd.1982.126.5.771" "Revista" => array:6 [ "tituloSerie" => "Am Rev Respir Dis" "fecha" => "1982" "volumen" => "126" "paginaInicial" => "771" "paginaFinal" => "777" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/6293352" "web" => "Medline" ] ] ] ] ] ] ] ] 33 => array:3 [ "identificador" => "bib0170" "etiqueta" => "34." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Long term survival and cure in lung cancer surgery" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "H.R. Sorensen" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "J Thorac Cardiovasc Surg" "fecha" => "1982" "volumen" => "30" "paginaInicial" => "292" "paginaFinal" => "293" ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "es" "url" => "/03002896/0000002400000004/v1_201509151100/S0300289615318305/v1_201509151100/es/main.assets" "Apartado" => array:4 [ "identificador" => "9277" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Originales" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/03002896/0000002400000004/v1_201509151100/S0300289615318305/v1_201509151100/es/main.pdf?idApp=UINPBA00003Z&text.app=https://archbronconeumol.org/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289615318305?idApp=UINPBA00003Z" ]
| Year/Month | Html | Total | |
|---|---|---|---|
| 2024 November | 6 | 2 | 8 |
| 2024 October | 47 | 17 | 64 |
| 2024 September | 34 | 21 | 55 |
| 2024 August | 76 | 36 | 112 |
| 2024 July | 42 | 26 | 68 |
| 2024 June | 50 | 22 | 72 |
| 2024 May | 31 | 18 | 49 |
| 2024 April | 30 | 20 | 50 |
| 2024 March | 35 | 18 | 53 |
| 2024 February | 23 | 27 | 50 |
| 2024 January | 0 | 4 | 4 |
| 2023 December | 0 | 1 | 1 |
| 2023 November | 0 | 4 | 4 |
| 2023 October | 0 | 7 | 7 |
| 2023 September | 0 | 2 | 2 |
| 2023 August | 0 | 1 | 1 |
| 2023 July | 0 | 15 | 15 |
| 2023 June | 0 | 3 | 3 |
| 2023 May | 0 | 2 | 2 |
| 2023 March | 4 | 2 | 6 |
| 2023 February | 16 | 17 | 33 |
| 2023 January | 17 | 33 | 50 |
| 2022 December | 24 | 26 | 50 |
| 2022 November | 24 | 22 | 46 |
| 2022 October | 25 | 29 | 54 |
| 2022 September | 23 | 12 | 35 |
| 2022 August | 23 | 28 | 51 |
| 2022 July | 23 | 31 | 54 |
| 2022 June | 28 | 31 | 59 |
| 2022 May | 23 | 25 | 48 |
| 2022 April | 26 | 37 | 63 |
| 2022 March | 37 | 34 | 71 |
| 2022 February | 27 | 25 | 52 |
| 2022 January | 26 | 42 | 68 |
| 2021 December | 20 | 29 | 49 |
| 2021 November | 15 | 22 | 37 |
| 2021 October | 21 | 45 | 66 |
| 2021 September | 25 | 35 | 60 |
| 2021 August | 6 | 11 | 17 |
| 2021 July | 6 | 20 | 26 |
| 2021 June | 13 | 23 | 36 |
| 2021 May | 9 | 17 | 26 |
| 2021 April | 5 | 36 | 41 |
| 2021 March | 40 | 19 | 59 |
| 2021 February | 34 | 14 | 48 |
| 2021 January | 25 | 10 | 35 |
| 2020 December | 22 | 5 | 27 |
| 2020 November | 7 | 12 | 19 |
| 2020 October | 12 | 6 | 18 |
| 2020 September | 9 | 10 | 19 |
| 2020 August | 20 | 9 | 29 |
| 2020 July | 21 | 10 | 31 |
| 2020 June | 10 | 13 | 23 |
| 2020 May | 24 | 13 | 37 |
| 2020 April | 13 | 5 | 18 |
| 2020 March | 13 | 18 | 31 |
| 2020 February | 14 | 14 | 28 |
| 2020 January | 33 | 13 | 46 |
| 2019 December | 25 | 24 | 49 |
| 2019 November | 6 | 5 | 11 |
| 2019 October | 8 | 6 | 14 |
| 2019 September | 6 | 16 | 22 |
| 2019 August | 11 | 4 | 15 |
| 2019 July | 18 | 27 | 45 |
| 2019 June | 31 | 10 | 41 |
| 2019 May | 12 | 17 | 29 |
| 2019 April | 10 | 33 | 43 |
| 2019 March | 4 | 13 | 17 |
| 2019 February | 2 | 4 | 6 |
| 2019 January | 5 | 3 | 8 |
| 2018 December | 7 | 6 | 13 |
| 2018 November | 12 | 11 | 23 |
| 2018 October | 16 | 7 | 23 |
| 2018 September | 12 | 5 | 17 |
| 2018 May | 6 | 1 | 7 |
| 2018 April | 10 | 5 | 15 |
| 2018 March | 5 | 5 | 10 |
| 2018 February | 7 | 8 | 15 |
| 2018 January | 7 | 1 | 8 |
| 2017 December | 8 | 12 | 20 |
| 2017 November | 9 | 8 | 17 |
| 2017 October | 9 | 7 | 16 |
| 2017 September | 2 | 3 | 5 |
| 2017 August | 11 | 20 | 31 |
| 2017 July | 4 | 13 | 17 |
| 2017 June | 9 | 12 | 21 |
| 2017 May | 12 | 10 | 22 |
| 2017 April | 5 | 4 | 9 |
| 2017 March | 10 | 8 | 18 |
| 2017 February | 3 | 9 | 12 |
| 2017 January | 6 | 5 | 11 |
| 2016 December | 2 | 5 | 7 |
| 2016 November | 20 | 13 | 33 |
| 2016 October | 22 | 20 | 42 |
| 2016 September | 17 | 6 | 23 |
| 2016 August | 15 | 6 | 21 |
| 2016 July | 21 | 7 | 28 |
| 2016 June | 22 | 9 | 31 |
| 2016 May | 17 | 7 | 24 |
| 2016 April | 7 | 0 | 7 |
| 2016 March | 10 | 0 | 10 |
| 2016 February | 14 | 1 | 15 |
| 2016 January | 14 | 6 | 20 |
| 2015 December | 17 | 12 | 29 |
| 2015 November | 22 | 8 | 30 |
| 2015 October | 7 | 2 | 9 |
Show all
