Bacterias recubiertas de anticuerpos en el esputo
Bacteria coated with antibodies in the sputum
C. Sala-Mateus, J. Puig de la Bellacasa, A. Torres, L. Hojman, M.T. Jiménez de Anta, A. Agustí Vidal
Servicios de Neumología y Microbiología. Hospital Clínico y Provincial. Barcelona
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Orriols, J.L. Aliaga, A. Román, F. Morell" "autores" => array:4 [ 0 => array:2 [ "nombre" => "R." "apellidos" => "Orriols" ] 1 => array:2 [ "nombre" => "J.L." "apellidos" => "Aliaga" ] 2 => array:2 [ "nombre" => "A." "apellidos" => "Román" ] 3 => array:2 [ "nombre" => "F." "apellidos" => "Morell" ] ] ] 1 => array:2 [ "autoresLista" => "J. Salvador, A. Segarra" "autores" => array:2 [ 0 => array:2 [ "nombre" => "J." "apellidos" => "Salvador" ] 1 => array:2 [ "nombre" => "A." "apellidos" => "Segarra" ] ] ] ] ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289615317774?idApp=UINPBA00003Z" "url" => "/03002896/0000002500000001/v1_201509151056/S0300289615317774/v1_201509151056/es/main.assets" ] "es" => array:13 [ "idiomaDefecto" => true "titulo" => "Bacterias recubiertas de anticuerpos en el esputo" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "14" "paginaFinal" => "17" ] ] "autores" => array:1 [ 0 => array:3 [ "autoresLista" => "C. Sala-Mateus, J. Puig de la Bellacasa, A. Torres, L. Hojman, M.T. Jiménez de Anta, A. Agustí Vidal" "autores" => array:6 [ 0 => array:2 [ "nombre" => "C." "apellidos" => "Sala-Mateus" ] 1 => array:2 [ "nombre" => "J." "apellidos" => "Puig de la Bellacasa" ] 2 => array:2 [ "nombre" => "A." "apellidos" => "Torres" ] 3 => array:2 [ "nombre" => "L." "apellidos" => "Hojman" ] 4 => array:2 [ "nombre" => "M.T." "apellidos" => "Jiménez de Anta" ] 5 => array:2 [ "nombre" => "A." "apellidos" => "Agustí Vidal" ] ] "afiliaciones" => array:1 [ 0 => array:2 [ "entidad" => "Servicios de Neumología y Microbiología. Hospital Clínico y Provincial. Barcelona" "identificador" => "aff0005" ] ] ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Bacteria coated with antibodies in the sputum" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "1988-07-18" "fechaAceptado" => "1988-10-19" "tieneResumen" => true "resumen" => array:2 [ "es" => array:1 [ "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">La detección de bacterias recubiertas de anticuerpos, mediante antigammaglobulinas humanas marcadas, en las secreciones del tracto respiratorio, ha sido propuesta como una técnica para identificar la infección bacteriana pulmonar. Este trabajo ha sido planificado para estudiar su valor diagnóstico en el esputo. Se estudian 14 muestras de esputos procedentes de pacientes con neumonía bacteriana y otras 14 de pacientes con otras bronconeumopatías. La sensibilidad de la técnica para el diagnóstico de las neumonías bacterianas fue del 86%, con una especificidad del 43%. Ello sugiere que dicha técnica no diferencia las bacterias que infectan las vías respiratorias de las que lo hacen en el parénquima pulmonar; aunque sí diferencia las bacterias que contaminan las muestras de esputo de las que causan infección. En nuestra serie, la toma previa de antibióticos no modificó los resultados. Las muestras más aptas para este estudio son las que contienen más de 25 leucocitos por campo (x 100). Finalmente, no se observaron diferencias en los resultados obtenidos en cada muestra empleando anti-IgG, anti-IgA y anti-IgM y el tiempo requerido para su positivización no incidió en el resultado, todo ello sugiere que la respuesta inmunitaria local pulmonar fue de tipo secundario.</p></span>" ] "en" => array:1 [ "resumen" => "<span id="abst0010" class="elsevierStyleSection elsevierViewall"><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">The detection by labeled human anti-gamma globulins of bacteria coated with antibodies in the secretions of the respiratory tract has been proposed as a method for identifying bacterial infections of the lung. The aim of the present work is to assess its diagnostic value in sputum samples. Fourteen sputum samples obtained from patients with bacterial pneumonia and 14 sputum samples from patients with other bronchopneumopathies were studied. Sensitivity and specificity of the method for diagnosing bacterial pneumonia were 86% and 43%, respectively, suggesting that such method do not distinguish between bacteria infecting airways from bacteria infecting lung parenchyma, but it allows to differentiate bacteria contaminating sputum samples from those causing infection. In our series, the previous treatment with antibiotics did not modify the results. The most appropriate samples for being studied are those containing more than 25 leukocytes per field (x 100). Finally, there were no differences in the results obtained in each sample employing anti-IgG, anti-IgA, or anti-IgM. The time required for positivation did not have any influence on the result, suggesting that the local immune response of the lung was of secondary type.</p></span>" ] ] "bibliografia" => array:2 [ "titulo" => "Bibliografia" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:17 [ 0 => array:3 [ "identificador" => "bib0005" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The non value of sputum culture in the diagnosis of pneumococcal pneumonia" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "E. 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| 2023 April | 0 | 9 | 9 |
| 2023 March | 8 | 24 | 32 |
| 2023 February | 29 | 106 | 135 |
| 2023 January | 26 | 114 | 140 |
| 2022 December | 31 | 118 | 149 |
| 2022 November | 45 | 135 | 180 |
| 2022 October | 39 | 142 | 181 |
| 2022 September | 33 | 152 | 185 |
| 2022 August | 52 | 141 | 193 |
| 2022 July | 69 | 118 | 187 |
| 2022 June | 86 | 157 | 243 |
| 2022 May | 51 | 136 | 187 |
| 2022 April | 72 | 141 | 213 |
| 2022 March | 61 | 119 | 180 |
| 2022 February | 46 | 133 | 179 |
| 2022 January | 52 | 135 | 187 |
| 2021 December | 23 | 121 | 144 |
| 2021 November | 23 | 129 | 152 |
| 2021 October | 26 | 211 | 237 |
| 2021 September | 19 | 172 | 191 |
| 2021 August | 11 | 159 | 170 |
| 2021 July | 62 | 174 | 236 |
| 2021 June | 26 | 169 | 195 |
| 2021 May | 23 | 144 | 167 |
| 2021 April | 47 | 245 | 292 |
| 2021 March | 50 | 192 | 242 |
| 2021 February | 59 | 113 | 172 |
| 2021 January | 38 | 104 | 142 |
| 2020 December | 26 | 105 | 131 |
| 2020 November | 16 | 99 | 115 |
| 2020 October | 21 | 88 | 109 |
| 2020 September | 28 | 108 | 136 |
| 2020 August | 35 | 99 | 134 |
| 2020 July | 22 | 77 | 99 |
| 2020 June | 24 | 91 | 115 |
| 2020 May | 23 | 91 | 114 |
| 2020 April | 14 | 83 | 97 |
| 2020 March | 25 | 102 | 127 |
| 2020 February | 36 | 84 | 120 |
| 2020 January | 29 | 63 | 92 |
| 2019 December | 35 | 73 | 108 |
| 2019 November | 9 | 62 | 71 |
| 2019 October | 8 | 79 | 87 |
| 2019 September | 11 | 60 | 71 |
| 2019 August | 12 | 50 | 62 |
| 2019 July | 8 | 46 | 54 |
| 2019 June | 20 | 73 | 93 |
| 2019 May | 22 | 47 | 69 |
| 2019 April | 39 | 55 | 94 |
| 2019 March | 7 | 29 | 36 |
| 2019 February | 9 | 26 | 35 |
| 2019 January | 7 | 16 | 23 |
| 2018 December | 7 | 15 | 22 |
| 2018 November | 12 | 22 | 34 |
| 2018 October | 20 | 19 | 39 |
| 2018 September | 9 | 11 | 20 |
| 2018 July | 0 | 1 | 1 |
| 2018 May | 5 | 1 | 6 |
| 2018 April | 17 | 10 | 27 |
| 2018 March | 4 | 10 | 14 |
| 2018 February | 6 | 9 | 15 |
| 2018 January | 8 | 14 | 22 |
| 2017 December | 9 | 19 | 28 |
| 2017 November | 13 | 32 | 45 |
| 2017 October | 17 | 41 | 58 |
| 2017 September | 8 | 17 | 25 |
| 2017 August | 13 | 29 | 42 |
| 2017 July | 13 | 26 | 39 |
| 2017 June | 18 | 43 | 61 |
| 2017 May | 17 | 22 | 39 |
| 2017 April | 15 | 33 | 48 |
| 2017 March | 8 | 14 | 22 |
| 2017 February | 7 | 18 | 25 |
| 2017 January | 5 | 7 | 12 |
| 2016 December | 15 | 15 | 30 |
| 2016 November | 22 | 18 | 40 |
| 2016 October | 33 | 21 | 54 |
| 2016 September | 20 | 23 | 43 |
| 2016 August | 20 | 14 | 34 |
| 2016 July | 23 | 9 | 32 |
| 2016 June | 26 | 15 | 41 |
| 2016 May | 19 | 10 | 29 |
| 2016 April | 6 | 1 | 7 |
| 2016 March | 6 | 0 | 6 |
| 2016 February | 5 | 3 | 8 |
| 2016 January | 26 | 8 | 34 |
| 2015 December | 34 | 23 | 57 |
| 2015 November | 30 | 10 | 40 |
| 2015 October | 8 | 5 | 13 |
| 2015 September | 2 | 0 | 2 |
Show all
