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        "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Hemos realizado un trabajo epidemiol&#243;gico de tipo transversal&#44; como parte de un estudio multic&#233;ntrico europeo&#44; con el objeto de estimar la prevalencia de sintomatolog&#237;a respiratoria y aquella relacionada con el asma presente en los &#250;ltimos 12 meses en la ciudad de Sevilla&#46; El estudio se realiz&#243; con una muestra de 4&#46;000 personas de ambos sexos&#44; con edades comprendidas entre 20 y 44 a&#241;os mediante el empleo de un cuestionario enviado por correo y posteriormente con el empleo de la entrevista por tel&#233;fono&#46; Analizamos el &#237;ndice de respuestas obtenido en el muestreo por correo en el estudio epidemiol&#243;gico sobre asma en nuestra zona&#44; as&#237; como la frecuencia de sintomatolog&#237;a respiratoria y su distribuci&#243;n por edad y sexo&#46; El &#237;ndice de respuestas fue de un 53&#44;36&#37;&#44; siendo similar en ambos sexos&#46; Presentaban alg&#250;n tipo de s&#237;ntoma respiratorio un 49&#37; de los encuestados&#44; siendo lo m&#225;s frecuente la existencia de ataques de tos nocturna &#40;27&#44;7&#37;&#41; y la presencia de sibilancias &#40;22&#44;2&#37;&#41;&#46; Sin embargo&#44; su frecuencia era diferente en ambos sexos&#44; siendo el primero de los s&#237;ntomas m&#225;s frecuente en mujeres &#40;p &#60; 0&#44;02&#41; y el segundo en varones &#40;p &#60; 0&#44;001&#41;&#46; Encontramos que un 14&#44;9&#37; de la poblaci&#243;n ten&#237;a s&#237;ntomas de rinitis y que este s&#237;ntoma era m&#225;s frecuente entre las mujeres &#40;p &#60; 0&#44;02&#41;&#46; Se consideraron s&#237;ntomas relacionados con el asma a la crisis de falta de aire nocturno&#44; la toma de medicaci&#243;n para el asma o el haber tenido alguna crisis de asma diagnosticada por un m&#233;dico en los &#250;ltimos 12 meses&#46; De esta forma la prevalencia estimada de asma fue de un 11&#44;72&#37;&#44; manteni&#233;ndose este porcentaje en todos los grupos de edad encuestados &#40;salvo en las edades medias&#41;&#44; y en ambos sexos&#46; Este porcentaje de sintom&#225;ticos se ha mantenido estable a lo largo de todo un a&#241;o&#46; El &#237;ndice de respuestas en este tipo de estudio es aceptable&#44; aunque no suficiente&#44; por lo que ha sido necesario realizar un <span class="elsevierStyleItalic">estudio de no-respuestas</span> analizando una muestra de 50 personas extra&#237;da de forma aleatoria de entre el grupo de no respondedores&#46; No encontramos diferencias ni entre las caracter&#237;sticas ni en la frecuencia de sintomatolog&#237;a o en la toma de medicaci&#243;n entre estas dos poblaciones&#44; por lo que consideramos los datos obtenidos con el 53&#44;36&#37; de la muestra como definitivos&#46;</p></span>"
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        "resumen" => "<span id="abst0010" class="elsevierStyleSection elsevierViewall"><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">This paper is a report of a cross-sectional epidemiological study that formed part of multicenter European project&#59; the aim was to est&#237;mate the prevalence of respiratory symptoms and signs related to asthma over a period of 12 months in the city of Seville&#46; A sample of 4&#44;000 persons of both sexes&#44; aged between 20 and 44 years o&#237;d&#44; was surveyed first by mail questionnaire and later by telephone interview&#46; We analyzed the response &#237;ndex obtained with the mail survey for the epidemiological study of asthma in the area and for the frequency of respiratory symptoms and their distribution by age and sex&#46; The response &#205;ndex was 53&#46;36&#37; and was similar for men and for woemen&#46; Forty-nine percent reported at least one respiratory symptom&#44; with nocturnal coughing attacks &#40;27&#46;7&#37;&#41; and wheezing &#40;22&#46;2&#37;&#41; being the most frequent&#46; The frequency of these symptoms was different by sex&#44; however&#44; with the former more often reported by women &#40;p &#60; 0&#46;02&#41; and the latter by men &#40;p &#60; 0&#46;001&#41;&#46; We found that 14&#46;9&#37; of the population had rhinitis and that women reported this symptom more often &#40;p &#60; 0&#46;02&#41;&#46; Symptoms related to asthma were nocturnal attacks of breathlessness&#44; the use of asthma medication and an asthma attack diagnosed by a physician within the last 12 months&#46; With these criteria the estimated prevalence of asthma was 11&#46;72&#37;&#44; a proportion that held steady for all age groups except the middle-aged and for both sexes&#46; The response index also held steady throughout the year of data collection and though it was typical of this type of study&#44; it was inadequate&#59; we were therefore obliged to study the non-respondents by analyzing a sample of 50 persons chosen randomly from among those who did not return the questionnaires&#46; No differences were found between these 2 samples with respect to frequency of symptoms or use of medication&#44; and we therefore consider the data obtained with 53&#46;36&#37; of the sample to be valid&#46;</p></span>"
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Análisis de la prevalencia de sintomatología respiratoria en la población general
Analysis of the prevalence of respiratory symptoms in the general population
J.A. Rodríguez Portal*, F.J. Álvarez Gutiérrez, A. Segado Soriano, G. Soto Campos, F. Capote Gil, J. Castillo Gómez
Servicio de Neumología. Hospital Universitario Virgen del Rocío. Sevilla
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    "titulosAlternativos" => array:1 [
      "en" => array:1 [
        "titulo" => "Analysis of the prevalence of respiratory symptoms in the general population"
      ]
    ]
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "fechaRecibido" => "1994-06-27"
    "fechaAceptado" => "1994-12-13"
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        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Palabras clave"
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          "palabras" => array:3 [
            0 => "Asma"
            1 => "Prevalencia"
            2 => "Epidemiolog&#237;a"
          ]
        ]
      ]
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        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Key words"
          "identificador" => "xpalclavsec546415"
          "palabras" => array:3 [
            0 => "Asthma"
            1 => "Prevalence"
            2 => "Epidemiology"
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        "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Hemos realizado un trabajo epidemiol&#243;gico de tipo transversal&#44; como parte de un estudio multic&#233;ntrico europeo&#44; con el objeto de estimar la prevalencia de sintomatolog&#237;a respiratoria y aquella relacionada con el asma presente en los &#250;ltimos 12 meses en la ciudad de Sevilla&#46; El estudio se realiz&#243; con una muestra de 4&#46;000 personas de ambos sexos&#44; con edades comprendidas entre 20 y 44 a&#241;os mediante el empleo de un cuestionario enviado por correo y posteriormente con el empleo de la entrevista por tel&#233;fono&#46; Analizamos el &#237;ndice de respuestas obtenido en el muestreo por correo en el estudio epidemiol&#243;gico sobre asma en nuestra zona&#44; as&#237; como la frecuencia de sintomatolog&#237;a respiratoria y su distribuci&#243;n por edad y sexo&#46; El &#237;ndice de respuestas fue de un 53&#44;36&#37;&#44; siendo similar en ambos sexos&#46; Presentaban alg&#250;n tipo de s&#237;ntoma respiratorio un 49&#37; de los encuestados&#44; siendo lo m&#225;s frecuente la existencia de ataques de tos nocturna &#40;27&#44;7&#37;&#41; y la presencia de sibilancias &#40;22&#44;2&#37;&#41;&#46; Sin embargo&#44; su frecuencia era diferente en ambos sexos&#44; siendo el primero de los s&#237;ntomas m&#225;s frecuente en mujeres &#40;p &#60; 0&#44;02&#41; y el segundo en varones &#40;p &#60; 0&#44;001&#41;&#46; Encontramos que un 14&#44;9&#37; de la poblaci&#243;n ten&#237;a s&#237;ntomas de rinitis y que este s&#237;ntoma era m&#225;s frecuente entre las mujeres &#40;p &#60; 0&#44;02&#41;&#46; Se consideraron s&#237;ntomas relacionados con el asma a la crisis de falta de aire nocturno&#44; la toma de medicaci&#243;n para el asma o el haber tenido alguna crisis de asma diagnosticada por un m&#233;dico en los &#250;ltimos 12 meses&#46; De esta forma la prevalencia estimada de asma fue de un 11&#44;72&#37;&#44; manteni&#233;ndose este porcentaje en todos los grupos de edad encuestados &#40;salvo en las edades medias&#41;&#44; y en ambos sexos&#46; Este porcentaje de sintom&#225;ticos se ha mantenido estable a lo largo de todo un a&#241;o&#46; El &#237;ndice de respuestas en este tipo de estudio es aceptable&#44; aunque no suficiente&#44; por lo que ha sido necesario realizar un <span class="elsevierStyleItalic">estudio de no-respuestas</span> analizando una muestra de 50 personas extra&#237;da de forma aleatoria de entre el grupo de no respondedores&#46; No encontramos diferencias ni entre las caracter&#237;sticas ni en la frecuencia de sintomatolog&#237;a o en la toma de medicaci&#243;n entre estas dos poblaciones&#44; por lo que consideramos los datos obtenidos con el 53&#44;36&#37; de la muestra como definitivos&#46;</p></span>"
      ]
      "en" => array:1 [
        "resumen" => "<span id="abst0010" class="elsevierStyleSection elsevierViewall"><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">This paper is a report of a cross-sectional epidemiological study that formed part of multicenter European project&#59; the aim was to est&#237;mate the prevalence of respiratory symptoms and signs related to asthma over a period of 12 months in the city of Seville&#46; A sample of 4&#44;000 persons of both sexes&#44; aged between 20 and 44 years o&#237;d&#44; was surveyed first by mail questionnaire and later by telephone interview&#46; We analyzed the response &#237;ndex obtained with the mail survey for the epidemiological study of asthma in the area and for the frequency of respiratory symptoms and their distribution by age and sex&#46; The response &#205;ndex was 53&#46;36&#37; and was similar for men and for woemen&#46; Forty-nine percent reported at least one respiratory symptom&#44; with nocturnal coughing attacks &#40;27&#46;7&#37;&#41; and wheezing &#40;22&#46;2&#37;&#41; being the most frequent&#46; The frequency of these symptoms was different by sex&#44; however&#44; with the former more often reported by women &#40;p &#60; 0&#46;02&#41; and the latter by men &#40;p &#60; 0&#46;001&#41;&#46; We found that 14&#46;9&#37; of the population had rhinitis and that women reported this symptom more often &#40;p &#60; 0&#46;02&#41;&#46; Symptoms related to asthma were nocturnal attacks of breathlessness&#44; the use of asthma medication and an asthma attack diagnosed by a physician within the last 12 months&#46; With these criteria the estimated prevalence of asthma was 11&#46;72&#37;&#44; a proportion that held steady for all age groups except the middle-aged and for both sexes&#46; The response index also held steady throughout the year of data collection and though it was typical of this type of study&#44; it was inadequate&#59; we were therefore obliged to study the non-respondents by analyzing a sample of 50 persons chosen randomly from among those who did not return the questionnaires&#46; No differences were found between these 2 samples with respect to frequency of symptoms or use of medication&#44; and we therefore consider the data obtained with 53&#46;36&#37; of the sample to be valid&#46;</p></span>"
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    ]
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                      "titulo" => "Developing a new questionnaire for measuring the prevalence and distribution of asthma"
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                      "titulo" => "Validity and repeatibility fo the IUATLD bronchial symptoms questionnaire&#58; an international comparison"
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                      "doi" => "10.1183/09031936.00111608"
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                        "fecha" => "1989"
                        "paginaInicial" => "940"
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                      "titulo" => "What symptoms predict the bronchial response to histamine&#63;&#46; Evaluation in a community survey of the bronchial symptoms questionnaire &#40;1984&#41; of the IUATLD"
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                          "etal" => false
                          "autores" => array:5 [
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                            1 => "S&#46; Chinn"
                            2 => "J&#46;R&#46; Britton"
                            3 => "A&#46;E&#46; Tattersfield"
                            4 => "A&#46;O&#46; Papacosta"
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                    0 => array:2 [
                      "titulo" => "Aspectos epidemiol&#243;gicos &#191;Por qu&#233; aumenta el asma&#63;&#46; II Curso SEPAR para residentes de neumolog&#237;a y cirug&#237;a tor&#225;cica"
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                          "autores" => array:1 [
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                      "Revista" => array:4 [
                        "tituloSerie" => "Libro de conferencias&#59;"
                        "fecha" => "1993"
                        "paginaInicial" => "10"
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              "identificador" => "bib0045"
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                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "A community-based study of the epidemiology of asthma&#46; Incidence rates&#44; 1964-83"
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                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "J&#46;W&#46; Yunginger"
                            1 => "C&#46;H&#46;E&#46; Read"
                            2 => "J&#46; O&#8217;Connell"
                            3 => "L&#46;J&#46; Melton"
                            4 => "W&#46;M&#46; O&#8217;Fallon"
                            5 => "M&#46;D&#46; Silverstein"
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                      "doi" => "10.1164/ajrccm/146.4.888"
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                        "fecha" => "1992"
                        "volumen" => "146"
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                        "paginaFinal" => "894"
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                  "contribucion" => array:1 [
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                      "titulo" => "Epidemiology"
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                          "etal" => false
                          "autores" => array:1 [
                            0 => "P&#46;G&#46;J&#46; Burney"
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                      "Revista" => array:6 [
                        "tituloSerie" => "British Medical Bulletin"
                        "fecha" => "1992"
                        "volumen" => "48"
                        "paginaInicial" => "10"
                        "paginaFinal" => "22"
                        "link" => array:1 [
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                            "web" => "Medline"
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            10 => array:3 [
              "identificador" => "bib0055"
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                    0 => array:2 [
                      "titulo" => "Asthma&#44; asthmalike symptoms&#44; chronic bronchitis&#44; and the degree of bronchial hyperresponsiveness in Epidemiological Surveys"
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                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "D&#46;A&#46; Enarson"
                            1 => "S&#46; Veda"
                            2 => "M&#46; Schulzer"
                            3 => "A&#46; Dybuncio"
                            4 => "M&#46; Chang-Yeung"
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                    ]
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                      "doi" => "10.1164/ajrccm/136.3.613"
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                        "tituloSerie" => "Am Rev Respir Dis"
                        "fecha" => "1987"
                        "volumen" => "136"
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                    0 => array:2 [
                      "titulo" => "Toward a Definition of asthma for epidemiology"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "B&#46;G&#46; Toelle"
                            1 => "J&#46;K&#46; Peat"
                            2 => "C&#46;M&#46; Salome"
                            3 => "C&#46;M&#46; Mellis"
                            4 => "A&#46;J&#46; Woolcock"
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                      ]
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                  ]
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                    0 => array:2 [
                      "doi" => "10.1164/ajrccm/146.3.633"
                      "Revista" => array:6 [
                        "tituloSerie" => "Am Rev Respir Dis"
                        "fecha" => "1992"
                        "volumen" => "146"
                        "paginaInicial" => "633"
                        "paginaFinal" => "637"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1519839"
                            "web" => "Medline"
                          ]
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                      ]
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                  ]
                ]
              ]
            ]
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              "identificador" => "bib0065"
              "etiqueta" => "13&#46;"
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                0 => array:2 [
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                    0 => array:2 [
                      "titulo" => "Resposta aun q&#252;estionari per correu o per tel&#233;fon&#46; A prop&#243;sit de la prova pilot a Barcelona de l&#8217;Estudi Europeu d&#8217;Asma"
                      "autores" => array:1 [
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                          "etal" => false
                          "autores" => array:4 [
                            0 => "J&#46;B&#46; Soriano"
                            1 => "J&#46; Sabr&#237;a"
                            2 => "I&#46; Sunyer"
                            3 => "J&#46;M&#46; Ant&#243;"
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                      ]
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                  ]
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                      "Revista" => array:5 [
                        "tituloSerie" => "Ann Med &#40;Bar&#41;"
                        "fecha" => "1992"
                        "volumen" => "6"
                        "paginaInicial" => "149"
                        "paginaFinal" => "153"
                      ]
                    ]
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              ]
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              "identificador" => "bib0070"
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                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Statistical Methods for rates and proportions"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "J&#46;L&#46; Fleiss"
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                    0 => array:1 [
                      "Libro" => array:6 [
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                        "paginaInicial" => "212"
                        "paginaFinal" => "236"
                        "editorial" => "John Willey and Sons"
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            14 => array:3 [
              "identificador" => "bib0075"
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                  "referenciaCompleta" => "EC Respiratory Health Survey General Meeting&#46; Lisbon&#44; december 13-14&#44; 1992&#46; Libro de res&#250;menes&#46; En prensa&#46;"
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            15 => array:3 [
              "identificador" => "bib0080"
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                    0 => array:2 [
                      "titulo" => "Response rates and asthma symptoms in Spain"
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                          "colaboracion" => "Spanish group of the European Respiratory health survey"
                          "etal" => false
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                        "fecha" => "1992"
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Article information
ISSN: 03002896
Original language: Spanish
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