Engrosamiento pleural en el derrame pleural tuberculoso. Factores asociados
Pleural thickening in tuberculosis pleural effusion. Associated factors
Servicio de Neumología. Hospital Universitario La Fe. Valencia
Read
4044
Timeswas read the article
2019
Total PDF
2025
Total HTML
Share statistics
array:23 [ "pii" => "S030028961530942X" "issn" => "03002896" "doi" => "10.1016/S0300-2896(15)30942-X" "estado" => "S300" "fechaPublicacion" => "1995-04-01" "aid" => "71012" "copyright" => "Sociedad Española de Neumología y Cirugía Torácica" "copyrightAnyo" => "1995" "documento" => "article" "crossmark" => 0 "subdocumento" => "fla" "cita" => "Arch Bronconeumol. 1995;31:157-61" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 1678 "formatos" => array:3 [ "EPUB" => 53 "HTML" => 864 "PDF" => 761 ] ] "itemSiguiente" => array:18 [ "pii" => "S0300289615309431" "issn" => "03002896" "doi" => "10.1016/S0300-2896(15)30943-1" "estado" => "S300" "fechaPublicacion" => "1995-04-01" "aid" => "71013" "copyright" => "Sociedad Española de Neumología y Cirugía Torácica" "documento" => "article" "crossmark" => 0 "subdocumento" => "fla" "cita" => "Arch Bronconeumol. 1995;31:162-8" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 1564 "formatos" => array:3 [ "EPUB" => 75 "HTML" => 952 "PDF" => 537 ] ] "es" => array:10 [ "idiomaDefecto" => true "titulo" => "Análisis de la prevalencia de sintomatología respiratoria en la población general" "tienePdf" => "es" "tieneTextoCompleto" => 0 "tieneResumen" => array:2 [ 0 => "es" 1 => "en" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "162" "paginaFinal" => "168" ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Analysis of the prevalence of respiratory symptoms in the general population" ] ] "contieneResumen" => array:2 [ "es" => true "en" => true ] "contienePdf" => array:1 [ "es" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "J.A. Rodríguez Portal, F.J. Álvarez Gutiérrez, A. Segado Soriano, G. Soto Campos, F. Capote Gil, J. Castillo Gómez" "autores" => array:6 [ 0 => array:2 [ "nombre" => "J.A." "apellidos" => "Rodríguez Portal" ] 1 => array:2 [ "nombre" => "F.J." "apellidos" => "Álvarez Gutiérrez" ] 2 => array:2 [ "nombre" => "A." "apellidos" => "Segado Soriano" ] 3 => array:2 [ "nombre" => "G." "apellidos" => "Soto Campos" ] 4 => array:2 [ "nombre" => "F." "apellidos" => "Capote Gil" ] 5 => array:2 [ "nombre" => "J." "apellidos" => "Castillo Gómez" ] ] ] ] ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289615309431?idApp=UINPBA00003Z" "url" => "/03002896/0000003100000004/v1_201506240047/S0300289615309431/v1_201506240047/es/main.assets" ] "itemAnterior" => array:18 [ "pii" => "S0300289615309418" "issn" => "03002896" "doi" => "10.1016/S0300-2896(15)30941-8" "estado" => "S300" "fechaPublicacion" => "1995-04-01" "aid" => "71011" "copyright" => "Sociedad Española de Neumología y Cirugía Torácica" "documento" => "article" "crossmark" => 0 "subdocumento" => "fla" "cita" => "Arch Bronconeumol. 1995;31:151-6" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 1311 "formatos" => array:3 [ "EPUB" => 74 "HTML" => 754 "PDF" => 483 ] ] "es" => array:10 [ "idiomaDefecto" => true "titulo" => "Seguimiento clínico y por medios de imagen a largo plazo de los filtros de vena cava inferior. Estudio transversal" "tienePdf" => "es" "tieneTextoCompleto" => 0 "tieneResumen" => array:2 [ 0 => "es" 1 => "en" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "151" "paginaFinal" => "156" ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Long-term clinical and imaging follow-up of patients with inferior vena cava filters. A cross-sectional study" ] ] "contieneResumen" => array:2 [ "es" => true "en" => true ] "contienePdf" => array:1 [ "es" => true ] "autores" => array:2 [ 0 => array:2 [ "autoresLista" => "M.A. de Gregorio, E.R. Alfonso, J.A. Fernández, I. Ariño, J. Medrano, J.L. Villavieja" "autores" => array:6 [ 0 => array:2 [ "nombre" => "M.A." "apellidos" => "de Gregorio" ] 1 => array:2 [ "nombre" => "E.R." "apellidos" => "Alfonso" ] 2 => array:2 [ "nombre" => "J.A." "apellidos" => "Fernández" ] 3 => array:2 [ "nombre" => "I." "apellidos" => "Ariño" ] 4 => array:2 [ "nombre" => "J." "apellidos" => "Medrano" ] 5 => array:2 [ "nombre" => "J.L." "apellidos" => "Villavieja" ] ] ] 1 => array:2 [ "autoresLista" => "A. Mainar, P. Rubio" "autores" => array:2 [ 0 => array:2 [ "nombre" => "A." "apellidos" => "Mainar" ] 1 => array:2 [ "nombre" => "P." "apellidos" => "Rubio" ] ] ] ] ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289615309418?idApp=UINPBA00003Z" "url" => "/03002896/0000003100000004/v1_201506240047/S0300289615309418/v1_201506240047/es/main.assets" ] "es" => array:14 [ "idiomaDefecto" => true "titulo" => "Engrosamiento pleural en el derrame pleural tuberculoso. Factores asociados" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "157" "paginaFinal" => "161" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "J.J. Soler, V. Gil Suay, P. Cordero, M. Perpiñá, E. Martínez, J. Sanchis" "autores" => array:6 [ 0 => array:3 [ "nombre" => "J.J." "apellidos" => "Soler" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor0005" ] ] ] 1 => array:2 [ "nombre" => "V." "apellidos" => "Gil Suay" ] 2 => array:2 [ "nombre" => "P." "apellidos" => "Cordero" ] 3 => array:2 [ "nombre" => "M." "apellidos" => "Perpiñá" ] 4 => array:2 [ "nombre" => "E." "apellidos" => "Martínez" ] 5 => array:2 [ "nombre" => "J." "apellidos" => "Sanchis" ] ] "afiliaciones" => array:1 [ 0 => array:2 [ "entidad" => "Servicio de Neumología. Hospital Universitario La Fe. Valencia" "identificador" => "aff0005" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "*" "correspondencia" => "Correspondencia: Servicio de Neumología. Hospital Universitario La Fe. Avda. Campanar, 21. Valencia." ] ] ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Pleural thickening in tuberculosis pleural effusion. Associated factors" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "1994-06-16" "fechaAceptado" => "1994-11-29" "PalabrasClave" => array:2 [ "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec546412" "palabras" => array:2 [ 0 => "Tuberculosis pleural" 1 => "Engrosamiento pleural" ] ] ] "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key words" "identificador" => "xpalclavsec546413" "palabras" => array:2 [ 0 => "Pleural tuberculosis" 1 => "Pleural thickening" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "es" => array:1 [ "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Nuestro objetivo ha sido determinar qué factores se relacionan con el desarrollo de engrosamiento pleural residual (EPR) al finalizar el tratamiento específico.</p><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Se estudian 62 pacientes diagnosticados de tuberculosis pleural (TP), separados en 2 grupos en función de la presencia o ausencia de EPR > 2 mm en la porción lateral e inferior de una radiografía posteroanterior de tórax, al finalizar el tratamiento específico. Ningún paciente recibió corticoides. El 72,6% presentó engrosamiento, siendo este más frecuente entre los varones (<span class="elsevierStyleItalic">odds ratio</span>, 4,06; p = 0,034), y en los enfermos de edad media superior, 36 ± 21 frente a 27 ± 12 años (p = 0,05). El hábito tabáquico, tamaño del derrame, duración de la sintomatología, encapsulamiento, PPD, biopsia pleural, bacteriología y el pH, glucosa, proteínas y colesterol del líquido pleural, así como sus respectivos cocientes pleura/suero fueron similares en ambos grupos. La LDH pleural (LDHp) y su relación pleura/suero (LDHp/s) fue 454,3 ± 234,6 U/l y 3,21 ± 1,67 en el grupo con EPR, por 306,0 ± 137,2 U/l y 2,00 ± 1,16 del grupo sin secuelas (p = 0,004 y p = 0,016, respectivamente). Utilizando como punto de corte una LDH p/s superior a 2,10, la sensibilidad obtenida fue del 78,9% con especificidad del 71,4%, valor predictivo positivo del 88,2% y valor predictivo negativo del 55,5%.</p><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Concluimos que: <span class="elsevierStyleItalic">a)</span> el EPR es una complicación frecuente; <span class="elsevierStyleItalic">b)</span> de predominio masculino; <span class="elsevierStyleItalic">c)</span> que guarda relación con la edad, y <span class="elsevierStyleItalic">d)</span> un valor superior a 2,10 en la relación LDH p/s puede predecir con aceptable seguridad la presencia de este trastorno.</p></span>" ] "en" => array:1 [ "resumen" => "<span id="abst0010" class="elsevierStyleSection elsevierViewall"><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">We aimed to determine which factors were related to the development of residual pleural thickening (RPT) after completion of prescribed treatment.</p><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">Sixty-two patients with pleural tuberculosis (PTB) were assigned to 2 groups according to the presence or absence of RPT > 2 mm in the side and lower portion of a chest film after completion of prescribed treatment. No patient had been given corticoids. Thickening developed in 72.6%, more often in men (OR, 4.06; p = 0.034), in older patients (36 ± 21 versus 27 ± 12 years; p = 0.05). Smoking, size of effusion, duration of symptoms, encapsulation, PPD, pleural biopsy, bacteriology and pH, glucose, proteins and cholesterol in pleural fluids, as well as their respective pleura/serum coefficients, were similar in both groups. Pleural LDH (LDHp) and its pleura/serum coefficient (LDHp/LDHs) were 454.3 ± 234.6 U/l and 3.21 ± 1.67 U/l in the group with RPT and 306.0 ± 137.2 U/l and 2.00 ± 1.16 in the group with no sequelae (p = 0.004 and p = 0.016, respectively). Using 2.10 as the cutoff for LDHp/LDHs, sensitivity was 78.9% and specificity was 71.4%, giving a positive predictive value of 88.2% and a negative predictive value of 55.5%.</p><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">We conclude that RPT <span class="elsevierStyleItalic">a)</span> is a frequent complication, <span class="elsevierStyleItalic">b)</span> is mainly found in men, <span class="elsevierStyleItalic">c)</span> is age-related and <span class="elsevierStyleItalic">d)</span> can be fairly safely predicted using 2.10 as the cutoff for LDHp/LDHs.</p></span>" ] ] "bibliografia" => array:2 [ "titulo" => "Bibliografía" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:22 [ 0 => array:3 [ "identificador" => "bib0005" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Estudio controlado de 637 pacientes con tuberculosis: diagnóstico y resultados terapéuticos con esquemas de 9 y 6 meses" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "R. Vidal" 1 => "J. De Gracia" 2 => "J. Ruiz" 3 => "E. Fite" 4 => "E. Monsó" 5 => "N. Martín" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Med Clin (Barc)" "fecha" => "1986" "volumen" => "87" "paginaInicial" => "368" "paginaFinal" => "370" ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib0010" "etiqueta" => "2." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Clinical forms of mycobacterial diseases" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "J.G. Weg" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "LibroEditado" => array:5 [ "titulo" => "Pulmonary diseases and disorders" "paginaInicial" => "1.843" "paginaFinal" => "1.862" "edicion" => "2. <span class="elsevierStyleSup">a</span>" "serieFecha" => "1988" ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib0015" "etiqueta" => "3." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Tuberculous pleural effusion: 6-month therapy with isoniazid and rifampin" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "A.K. Dutt" 1 => "D. Moers" 2 => "W.W. Stead" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1164/ajrccm/145.6.1503" "Revista" => array:6 [ "tituloSerie" => "Am Rev Respir Dis" "fecha" => "1992" "volumen" => "145" "paginaInicial" => "1.429" "paginaFinal" => "1.432" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1596027" "web" => "Medline" ] ] ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib0020" "etiqueta" => "4." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Corticosteroids in the treatment of tuberculous pleurisy. A double-blind, placebo-controlled, randomized study" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "C.H. Lee" 1 => "W.J. Wang" 2 => "R.S. Lan" 3 => "Y.F.I. Tsai" 4 => "Y.C. Chiang" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Chest" "fecha" => "1988" "volumen" => "94" "paginaInicial" => "1.256" "paginaFinal" => "1.259" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3263910" "web" => "Medline" ] ] ] ] ] ] ] ] 4 => array:3 [ "identificador" => "bib0025" "etiqueta" => "5." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Zur epidemiologie der pleuritis tuberculosa in der Bundesrepublik Deutschland" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "G. Neummann" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Prax KJin Pneumol" "fecha" => "1984" "volumen" => "38" "paginaInicial" => "392" "paginaFinal" => "396" ] ] ] ] ] ] 5 => array:3 [ "identificador" => "bib0030" "etiqueta" => "6." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Clinical and pathological features of tuberculous pleural effusion and its long-term consequences" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "C.H.S. Chan" 1 => "M. Arnold" 2 => "C.Y. Chan" 3 => "T.W.L. Mak" 4 => "G.B. Hoheisel" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Respiration" "fecha" => "1991" "volumen" => "58" "paginaInicial" => "171" "paginaFinal" => "175" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1745850" "web" => "Medline" ] ] ] ] ] ] ] ] 6 => array:3 [ "identificador" => "bib0035" "etiqueta" => "7." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The relationship between pleural fluid fíndings and the Development of pleural thickening in patient with pleural tuberculosis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "C.S. Barbas" 1 => "A. Cukier" 2 => "C.R. Varvalho" 3 => "J.V. Barbas" 4 => "R.W. Light" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Chest" "fecha" => "1991" "volumen" => "100" "paginaInicial" => "1.264" "paginaFinal" => "1.267" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1835689" "web" => "Medline" ] ] ] ] ] ] ] ] 7 => array:3 [ "identificador" => "bib0040" "etiqueta" => "8." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Cortisone therapy for exudative tuberculous pleurisy in the light of follow-up study" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "P. Tani" 1 => "H. Poppius" 2 => "J. Makipaja" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Acta Tuberc Scand" "fecha" => "1964" "volumen" => "44" "paginaInicial" => "303" "paginaFinal" => "309" ] ] ] ] ] ] 8 => array:3 [ "identificador" => "bib0045" "etiqueta" => "9." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Treatment of tuberculous pleural effusion with local instillation of hydrocortisone" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "K.S. Mathur" 1 => "J.S. Mathur" 2 => "R.P. Sapru" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Dis Chest" "fecha" => "1965" "volumen" => "47" "paginaInicial" => "83" "paginaFinal" => "87" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/14254168" "web" => "Medline" ] ] ] ] ] ] ] ] 9 => array:3 [ "identificador" => "bib0050" "etiqueta" => "10." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Treatment of tuberculous pleural effusions with particular reference to adrenal corticosteroids" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "M.H.D. Smith" 1 => "N. Matsaniotis" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Pediatrics" "fecha" => "1958" "volumen" => "22" "paginaInicial" => "1.074" "paginaFinal" => "1.087" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11691946" "web" => "Medline" ] ] ] ] ] ] ] ] 10 => array:3 [ "identificador" => "bib0055" "etiqueta" => "11." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Prednisone in the treatment of tuberculous pleural effusions" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "S.S. Paley" 1 => "J.P. Mihaly" 2 => "E.L. Mais" 3 => "S.A. Gittens" 4 => "B. Lupini" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Am Rev Tuberc" "fecha" => "1959" "volumen" => "79" "paginaInicial" => "307" "paginaFinal" => "314" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/13627437" "web" => "Medline" ] ] ] ] ] ] ] ] 11 => array:3 [ "identificador" => "bib0060" "etiqueta" => "12." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Aspiration in the treatment of primary tuberculous pleural effusion" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "S.E. Large" 1 => "R.K. Levick" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "BMJ" "fecha" => "1958" "volumen" => "1" "paginaInicial" => "1.512" "paginaFinal" => "1.514" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/20792883" "web" => "Medline" ] ] ] ] ] ] ] ] 12 => array:3 [ "identificador" => "bib0065" "etiqueta" => "13." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Sex steroids and the rheumatic diseases" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "R.G. Lahita" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Arthritis Rheum" "fecha" => "1985" "volumen" => "28" "paginaInicial" => "121" "paginaFinal" => "162" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3871614" "web" => "Medline" ] ] ] ] ] ] ] ] 13 => array:3 [ "identificador" => "bib0070" "etiqueta" => "14." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Oestradiol-and testoreone-mediated effects on the immune system in normal and autoinmune mice are genetically linked and inherited as dominant traits" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "H. Carlsten" 1 => "R. Holmdahl" 2 => "A. Tarkowski" 3 => "Nilsson" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Immunology" "fecha" => "1989" "volumen" => "68" "paginaInicial" => "209" "paginaFinal" => "214" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2807378" "web" => "Medline" ] ] ] ] ] ] ] ] 14 => array:3 [ "identificador" => "bib0075" "etiqueta" => "15." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Anti-inflammatory properties of estrogen" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "E. Josefsson" 1 => "A. Tarkowski" 2 => "H. Carlsten" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Cell-Immunol" "fecha" => "1992" "volumen" => "142" "paginaInicial" => "67" "paginaFinal" => "78" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1586960" "web" => "Medline" ] ] ] ] ] ] ] ] 15 => array:3 [ "identificador" => "bib0080" "etiqueta" => "16." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Pleural diseases" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "R.W. Light" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Libro" => array:4 [ "edicion" => "2.<span class="elsevierStyleSup">a</span> ed." "fecha" => "1990" "editorial" => "Lea and Febiger" "editorialLocalizacion" => "Filadelfia" ] ] ] ] ] ] 16 => array:3 [ "identificador" => "bib0085" "etiqueta" => "17." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Lactate dehydrogenase isoenzymes in pleural effusions" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "R.W. Light" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1164/arrd.1973.108.3.660" "Revista" => array:6 [ "tituloSerie" => "Am Rev Respir Dis" "fecha" => "1973" "volumen" => "108" "paginaInicial" => "660" "paginaFinal" => "664" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/4745262" "web" => "Medline" ] ] ] ] ] ] ] ] 17 => array:3 [ "identificador" => "bib0090" "etiqueta" => "18." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Lymphocyte subpopulations analysis in pleural fluid and peripheral blood in patients with lymphocytic pleural effusions" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "C. Albera" 1 => "I. Mabritto" 2 => "P. Ghio" 3 => "G.V. Scagliotti" 4 => "E. Pozzi" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Respiration" "fecha" => "1991" "volumen" => "58" "paginaInicial" => "65" "paginaFinal" => "71" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1677776" "web" => "Medline" ] ] ] ] ] ] ] ] 18 => array:3 [ "identificador" => "bib0095" "etiqueta" => "19." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "T and B lymphocytes in pleural effusions" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "T. Petterson" 1 => "M. Klockars" 2 => "P.E. Hellstrom" 3 => "H. Riska" 4 => "A. Wangel" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:4 [ "tituloSerie" => "Chest" "fecha" => "1978" "volumen" => "73" "paginaInicial" => "4951" ] ] ] ] ] ] 19 => array:3 [ "identificador" => "bib0100" "etiqueta" => "20." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "High level of interferon gamma in tuberculous pleural effusion" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "E. Ribera" 1 => "I. Ocaña" 2 => "J.M. Martínez-Vázquez" 3 => "M. Rosell" 4 => "T. Español" 5 => "A. Ruibal" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Chest" "fecha" => "1988" "volumen" => "93" "paginaInicial" => "308" "paginaFinal" => "311" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3123150" "web" => "Medline" ] ] ] ] ] ] ] ] 20 => array:3 [ "identificador" => "bib0105" "etiqueta" => "21." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Cytokines of the lung" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "J. Kelly" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1164/ajrccm/141.3.765" "Revista" => array:6 [ "tituloSerie" => "Am Rev Respir Dis" "fecha" => "1990" "volumen" => "141" "paginaInicial" => "765" "paginaFinal" => "788" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2155556" "web" => "Medline" ] ] ] ] ] ] ] ] 21 => array:3 [ "identificador" => "bib0110" "etiqueta" => "22." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Cytokine content in pleural effusion. Comparison between tuberculous and carcinomatous pleurisy" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "K. Shimokata" 1 => "H. Saka" 2 => "T. Murate" 3 => "Y. Hasegawa" 4 => "T. Hasegawa" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Chest" "fecha" => "1991" "volumen" => "99" "paginaInicial" => "1.103" "paginaFinal" => "1.107" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2036855" "web" => "Medline" ] ] ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "es" "url" => "/03002896/0000003100000004/v1_201506240047/S030028961530942X/v1_201506240047/es/main.assets" "Apartado" => array:4 [ "identificador" => "9277" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Originales" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/03002896/0000003100000004/v1_201506240047/S030028961530942X/v1_201506240047/es/main.pdf?idApp=UINPBA00003Z&text.app=https://archbronconeumol.org/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S030028961530942X?idApp=UINPBA00003Z" ]
| Year/Month | Html | Total | |
|---|---|---|---|
| 2024 November | 4 | 1 | 5 |
| 2024 October | 34 | 13 | 47 |
| 2024 September | 41 | 14 | 55 |
| 2024 August | 45 | 36 | 81 |
| 2024 July | 39 | 38 | 77 |
| 2024 June | 53 | 54 | 107 |
| 2024 May | 39 | 19 | 58 |
| 2024 April | 27 | 22 | 49 |
| 2024 March | 39 | 30 | 69 |
| 2024 February | 27 | 43 | 70 |
| 2024 January | 0 | 3 | 3 |
| 2023 December | 0 | 2 | 2 |
| 2023 November | 0 | 1 | 1 |
| 2023 October | 0 | 5 | 5 |
| 2023 September | 0 | 2 | 2 |
| 2023 July | 0 | 18 | 18 |
| 2023 June | 0 | 2 | 2 |
| 2023 May | 0 | 1 | 1 |
| 2023 March | 2 | 3 | 5 |
| 2023 February | 28 | 21 | 49 |
| 2023 January | 26 | 24 | 50 |
| 2022 December | 31 | 20 | 51 |
| 2022 November | 31 | 29 | 60 |
| 2022 October | 36 | 61 | 97 |
| 2022 September | 27 | 31 | 58 |
| 2022 August | 28 | 38 | 66 |
| 2022 July | 14 | 29 | 43 |
| 2022 June | 30 | 22 | 52 |
| 2022 May | 24 | 30 | 54 |
| 2022 April | 31 | 30 | 61 |
| 2022 March | 34 | 29 | 63 |
| 2022 February | 23 | 32 | 55 |
| 2022 January | 28 | 27 | 55 |
| 2021 December | 13 | 29 | 42 |
| 2021 November | 15 | 44 | 59 |
| 2021 October | 14 | 44 | 58 |
| 2021 September | 16 | 44 | 60 |
| 2021 August | 12 | 30 | 42 |
| 2021 July | 15 | 42 | 57 |
| 2021 June | 17 | 37 | 54 |
| 2021 May | 24 | 31 | 55 |
| 2021 April | 14 | 43 | 57 |
| 2021 March | 19 | 20 | 39 |
| 2021 February | 44 | 21 | 65 |
| 2021 January | 12 | 13 | 25 |
| 2020 December | 21 | 18 | 39 |
| 2020 November | 15 | 11 | 26 |
| 2020 October | 22 | 10 | 32 |
| 2020 September | 17 | 3 | 20 |
| 2020 August | 15 | 24 | 39 |
| 2020 July | 29 | 18 | 47 |
| 2020 June | 12 | 8 | 20 |
| 2020 May | 15 | 12 | 27 |
| 2020 April | 20 | 6 | 26 |
| 2020 March | 31 | 14 | 45 |
| 2020 February | 26 | 13 | 39 |
| 2020 January | 44 | 24 | 68 |
| 2019 December | 33 | 28 | 61 |
| 2019 November | 10 | 13 | 23 |
| 2019 October | 22 | 14 | 36 |
| 2019 September | 11 | 19 | 30 |
| 2019 August | 19 | 5 | 24 |
| 2019 July | 16 | 25 | 41 |
| 2019 June | 21 | 21 | 42 |
| 2019 May | 29 | 33 | 62 |
| 2019 April | 46 | 36 | 82 |
| 2019 March | 13 | 22 | 35 |
| 2019 February | 10 | 7 | 17 |
| 2019 January | 10 | 14 | 24 |
| 2018 December | 9 | 13 | 22 |
| 2018 November | 10 | 19 | 29 |
| 2018 October | 15 | 12 | 27 |
| 2018 September | 18 | 8 | 26 |
| 2018 May | 8 | 1 | 9 |
| 2018 April | 11 | 7 | 18 |
| 2018 March | 9 | 6 | 15 |
| 2018 February | 11 | 7 | 18 |
| 2018 January | 7 | 6 | 13 |
| 2017 December | 9 | 18 | 27 |
| 2017 November | 6 | 12 | 18 |
| 2017 October | 15 | 30 | 45 |
| 2017 September | 9 | 29 | 38 |
| 2017 August | 14 | 25 | 39 |
| 2017 July | 5 | 16 | 21 |
| 2017 June | 13 | 37 | 50 |
| 2017 May | 20 | 37 | 57 |
| 2017 April | 13 | 22 | 35 |
| 2017 March | 8 | 29 | 37 |
| 2017 February | 6 | 17 | 23 |
| 2017 January | 1 | 9 | 10 |
| 2016 December | 36 | 11 | 47 |
| 2016 November | 37 | 18 | 55 |
| 2016 October | 18 | 14 | 32 |
| 2016 September | 24 | 24 | 48 |
| 2016 August | 22 | 10 | 32 |
| 2016 July | 22 | 9 | 31 |
| 2016 June | 23 | 12 | 35 |
| 2016 May | 26 | 8 | 34 |
| 2016 April | 12 | 0 | 12 |
| 2016 March | 15 | 0 | 15 |
| 2016 February | 12 | 0 | 12 |
| 2016 January | 22 | 8 | 30 |
| 2015 December | 27 | 11 | 38 |
| 2015 November | 29 | 6 | 35 |
| 2015 October | 10 | 2 | 12 |
| 2015 September | 4 | 0 | 4 |
| 2015 August | 5 | 0 | 5 |
| 2015 June | 1 | 0 | 1 |
Show all
