Resistencia de Mycobacterium tuberculosis en la provincia de Castellón
Resistant Mycobucterium tuberculosis in the province of Castellón
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"apellidos" => "Prada Alfaro" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">***</span>" "identificador" => "aff0015" ] ] ] ] "afiliaciones" => array:3 [ 0 => array:3 [ "entidad" => "Servicio de Microbiología. Dirección Territorial de Sanidad. Castellón" "etiqueta" => "*" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "Sección de Epidemiología. Dirección Territorial de Sanidad. Castellón" "etiqueta" => "**" "identificador" => "aff0010" ] 2 => array:3 [ "entidad" => "Sección de Neumología. Servicio de Medicina Interna. Hospital General de Castellón" "etiqueta" => "***" "identificador" => "aff0015" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "1" "correspondencia" => "Correspondencia: Servicio de Microbiología. Hospital General de Castellón. Avda. Benicasin. s/n. 12004 Castellón." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Resistant <span class="elsevierStyleItalic">Mycobucterium tuberculosis</span> in the province of Castellón" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "1995-07-03" "fechaAceptado" => "1995-09-19" "PalabrasClave" => array:2 [ "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec546114" "palabras" => array:2 [ 0 => "Mycobacterium tuberculosis" 1 => "Resistencia" ] ] ] "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key words" "identificador" => "xpalclavsec546115" "palabras" => array:2 [ 0 => "Mycobacterium tuberculosis" 1 => "Resistance" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "es" => array:1 [ "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Se realizó un estudio transversal para conocer la prevalencia de micobacterias resistentes en nuestro medio. Formaron parte del estudio todos los pacientes en los que se aisló <span class="elsevierStyleItalic">M. tuberculosis</span> en el cultivo de una muestra clínica (119) durante el período comprendido entre enero de 1992 y diciembre de 1993. El estudio de sensibilidad se realizó con el método de las proporciones de Canetti, investigándose los siguientes fármacos: isoniacida, rifampicina, estreptomicina, etambutol y ácido paraaminosalicílico.</p><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">La resistencia global que mostró <span class="elsevierStyleItalic">M. tuberculosis</span> fue del 9,24%. Por fármacos, un 5,9% eran resistentes a isoniacida, un 4,20% a estreptomicina, un 5,04% a rifampicina y un 1,68% a etambutol. Las resistencias fueron primarias en un 7% y secundarias en el 21,05%. Las resistencias primarias correspondían en un 2% a isoniacida, 1% a isoniacida y rifampicina, 2% a estreptomicina, 1% a etambutol y 1% a estreptomicina y rifampicina. El índice de resistencias está en la línea de las publicadas en otras zonas del país.</p></span>" ] "en" => array:1 [ "resumen" => "<span id="abst0010" class="elsevierStyleSection elsevierViewall"><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">We conduced a cross-sectional study to determine the prevalence of resistant mycobacteria in our setting. All patients in whom <span class="elsevierStyleItalic">M. tuberculosis</span> had been isolated in cultures of clinical samples (119) between January 1992 and December 1993 took part in the study. Canetti's method of percentages was used for the study of sensitivity to the following drugs: isocyanide, rifampicin, streptomycin, ethambutol and para-aminosalicylic acid.</p><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">Overall resistance of <span class="elsevierStyleItalic">M. tuberculosis</span> was 9.24%. Specifically, we found resistance to isocyanide in 5.9%, to streptomycin in 4.20%, to rifampicin in 5.04% and to ethambutol in 1.68%. Resistance was primary in 7% and secondary in 21.05%; 2% showed primary resistance to isocyanide. 1% to isocyanide and rifampicin, 2% to streptomycin, 1% to ethambutol and 1% to streptomycin and rifampicin. These resistance indices are in keeping with those published for other areas of Spain.</p></span>" ] ] "bibliografia" => array:2 [ "titulo" => "Bibliografía" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:21 [ 0 => array:3 [ "identificador" => "bib0005" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Actualidad de la tuberculosis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "L. Martínez" 1 => "J. 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"referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Consenso nacional para el control de la tuberculosis en España" "autores" => array:1 [ 0 => array:2 [ "colaboracion" => "Grupo de Trabajo sobre Tuberculosis" "etal" => false ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Med Clin (Barc)" "fecha" => "1992" "volumen" => "98" "paginaInicial" => "24" "paginaFinal" => "31" ] ] ] ] ] ] 15 => array:3 [ "identificador" => "bib0080" "etiqueta" => "16." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Incidencia de <span class="elsevierStyleItalic">Mycobacterium tuberculosis</span> resistente a tuberculostáticos en un hospital general" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "M.C. Nogales" 1 => "A.L. Aller" 2 => "E. Martín Mazuelos" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Rev Esp Quimioterap" "fecha" => "1995" "volumen" => "8" "paginaInicial" => "51" "paginaFinal" => "54" ] ] ] ] ] ] 16 => array:3 [ "identificador" => "bib0085" "etiqueta" => "17." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Resistencia de <span class="elsevierStyleItalic">Mycobacterium tuberculosis</span> a fármacos en un área de tuberculosis endémica" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "M.L. Pérez del Molino" 1 => "F. Pardo" 2 => "E. Carballo" 3 => "M.C. Gutiérrez" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Rev Esp Quimioterap" "fecha" => "1994" "volumen" => "7" "paginaInicial" => "137" "paginaFinal" => "141" ] ] ] ] ] ] 17 => array:3 [ "identificador" => "bib0090" "etiqueta" => "18." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Estudio de las resistencias bacterianas primarias e iniciales en enfermos tuberculosos de un hospital general durante 1983-1987" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "V. Ausina" 1 => "M. García-Barceló" 2 => "M. Luquin" 3 => "F. Belda" 4 => "J. Fernández" 5 => "G. Esteban" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Enf Infecc Microbiol Clin" "fecha" => "1990" "volumen" => "8" "paginaInicial" => "274" "paginaFinal" => "277" ] ] ] ] ] ] 18 => array:3 [ "identificador" => "bib0095" "etiqueta" => "19." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Tuberculosis resistente en una población penitenciaria durante el período 1991-1993" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "F. Chaves" 1 => "F. Dionda" 2 => "A. 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De March Ayuda" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Med Clin (Barc)" "fecha" => "1994" "volumen" => "102" "paginaInicial" => "98" "paginaFinal" => "100" ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "es" "url" => "/03002896/0000003200000003/v1_201506230045/S0300289615307961/v1_201506230045/es/main.assets" "Apartado" => array:4 [ "identificador" => "9277" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Originales" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/03002896/0000003200000003/v1_201506230045/S0300289615307961/v1_201506230045/es/main.pdf?idApp=UINPBA00003Z&text.app=https://archbronconeumol.org/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289615307961?idApp=UINPBA00003Z" ]
| Year/Month | Html | Total | |
|---|---|---|---|
| 2024 November | 5 | 2 | 7 |
| 2024 October | 39 | 15 | 54 |
| 2024 September | 43 | 13 | 56 |
| 2024 August | 51 | 34 | 85 |
| 2024 July | 36 | 31 | 67 |
| 2024 June | 56 | 25 | 81 |
| 2024 May | 55 | 39 | 94 |
| 2024 April | 31 | 58 | 89 |
| 2024 March | 39 | 31 | 70 |
| 2024 February | 33 | 33 | 66 |
| 2024 January | 0 | 3 | 3 |
| 2023 December | 0 | 1 | 1 |
| 2023 November | 0 | 2 | 2 |
| 2023 October | 0 | 7 | 7 |
| 2023 September | 0 | 6 | 6 |
| 2023 August | 0 | 1 | 1 |
| 2023 July | 0 | 2 | 2 |
| 2023 June | 0 | 1 | 1 |
| 2023 May | 0 | 2 | 2 |
| 2023 March | 17 | 3 | 20 |
| 2023 February | 56 | 20 | 76 |
| 2023 January | 22 | 29 | 51 |
| 2022 December | 35 | 23 | 58 |
| 2022 November | 38 | 23 | 61 |
| 2022 October | 28 | 33 | 61 |
| 2022 September | 22 | 20 | 42 |
| 2022 August | 35 | 40 | 75 |
| 2022 July | 22 | 27 | 49 |
| 2022 June | 23 | 39 | 62 |
| 2022 May | 35 | 31 | 66 |
| 2022 April | 39 | 38 | 77 |
| 2022 March | 35 | 39 | 74 |
| 2022 February | 45 | 23 | 68 |
| 2022 January | 24 | 37 | 61 |
| 2021 December | 14 | 33 | 47 |
| 2021 November | 27 | 34 | 61 |
| 2021 October | 23 | 41 | 64 |
| 2021 September | 20 | 31 | 51 |
| 2021 August | 26 | 25 | 51 |
| 2021 July | 26 | 27 | 53 |
| 2021 June | 21 | 31 | 52 |
| 2021 May | 16 | 29 | 45 |
| 2021 April | 34 | 52 | 86 |
| 2021 March | 49 | 19 | 68 |
| 2021 February | 22 | 14 | 36 |
| 2021 January | 15 | 8 | 23 |
| 2020 December | 16 | 15 | 31 |
| 2020 November | 11 | 12 | 23 |
| 2020 October | 11 | 5 | 16 |
| 2020 September | 21 | 5 | 26 |
| 2020 August | 20 | 10 | 30 |
| 2020 July | 26 | 24 | 50 |
| 2020 June | 14 | 19 | 33 |
| 2020 May | 19 | 16 | 35 |
| 2020 April | 31 | 15 | 46 |
| 2020 March | 30 | 22 | 52 |
| 2020 February | 28 | 29 | 57 |
| 2020 January | 43 | 28 | 71 |
| 2019 December | 36 | 23 | 59 |
| 2019 November | 8 | 12 | 20 |
| 2019 October | 15 | 23 | 38 |
| 2019 September | 15 | 28 | 43 |
| 2019 August | 23 | 12 | 35 |
| 2019 July | 10 | 32 | 42 |
| 2019 June | 13 | 27 | 40 |
| 2019 May | 21 | 25 | 46 |
| 2019 April | 35 | 27 | 62 |
| 2019 March | 11 | 19 | 30 |
| 2019 February | 6 | 12 | 18 |
| 2019 January | 5 | 12 | 17 |
| 2018 December | 8 | 12 | 20 |
| 2018 November | 10 | 24 | 34 |
| 2018 October | 29 | 12 | 41 |
| 2018 September | 27 | 11 | 38 |
| 2018 May | 7 | 2 | 9 |
| 2018 April | 17 | 9 | 26 |
| 2018 March | 12 | 7 | 19 |
| 2018 February | 7 | 11 | 18 |
| 2018 January | 4 | 4 | 8 |
| 2017 December | 15 | 11 | 26 |
| 2017 November | 6 | 11 | 17 |
| 2017 October | 7 | 17 | 24 |
| 2017 September | 5 | 5 | 10 |
| 2017 August | 13 | 17 | 30 |
| 2017 July | 3 | 6 | 9 |
| 2017 June | 18 | 26 | 44 |
| 2017 May | 13 | 12 | 25 |
| 2017 April | 8 | 8 | 16 |
| 2017 March | 8 | 20 | 28 |
| 2017 February | 9 | 10 | 19 |
| 2017 January | 5 | 8 | 13 |
| 2016 December | 32 | 14 | 46 |
| 2016 November | 37 | 28 | 65 |
| 2016 October | 50 | 25 | 75 |
| 2016 September | 32 | 11 | 43 |
| 2016 August | 26 | 9 | 35 |
| 2016 July | 27 | 5 | 32 |
| 2016 June | 27 | 7 | 34 |
| 2016 May | 26 | 8 | 34 |
| 2016 April | 19 | 0 | 19 |
| 2016 March | 13 | 0 | 13 |
| 2016 February | 11 | 1 | 12 |
| 2016 January | 15 | 6 | 21 |
| 2015 December | 23 | 14 | 37 |
| 2015 November | 38 | 9 | 47 |
| 2015 October | 11 | 2 | 13 |
| 2015 September | 1 | 0 | 1 |
| 2015 June | 1 | 0 | 1 |
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