Exactitud y validez del umbral láctico frente a otros métodos no invasivos de medición del umbral anaerobio en pacientes con miopatías metabólicas
Accuracy and validity of the lactic acidosis threshold in comparison with other non invasive methods of measuring the anaerobic threshold in patients with metabolic myopathies
Servicio de Neumología. Hospital Universitario Virgen del Rocío. Sevilla
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"apellidos" => "Santos" ] 1 => array:2 [ "nombre" => "R." "apellidos" => "Lorente" ] ] ] ] ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289615307821?idApp=UINPBA00003Z" "url" => "/03002896/0000003200000004/v1_201506230047/S0300289615307821/v1_201506230047/es/main.assets" ] "es" => array:15 [ "idiomaDefecto" => true "titulo" => "Exactitud y validez del umbral láctico frente a otros métodos no invasivos de medición del umbral anaerobio en pacientes con miopatías metabólicas" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "176" "paginaFinal" => "182" ] ] "autores" => array:2 [ 0 => array:4 [ "autoresLista" => "J. Fernández Guerra, T. Montemayor Rubio, F. Ortega Ruiz, J. Castillo Gómez" "autores" => array:4 [ 0 => array:3 [ "nombre" => "J." "apellidos" => "Fernández Guerra" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">1</span>" "identificador" => "cor0005" ] ] ] 1 => array:2 [ "nombre" => "T." "apellidos" => "Montemayor Rubio" ] 2 => array:2 [ "nombre" => "F." "apellidos" => "Ortega Ruiz" ] 3 => array:2 [ "nombre" => "J." "apellidos" => "Castillo Gómez" ] ] "afiliaciones" => array:1 [ 0 => array:2 [ "entidad" => "Servicio de Neumología. Hospital Universitario Virgen del Rocío. Sevilla" "identificador" => "aff0005" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "1" "correspondencia" => "Correspondencia: Juan de Mariana, 15, 3.°. 41005 Sevilla." ] ] ] 1 => array:3 [ "autoresLista" => "J. Bautista Lorite, R. Márquez, L. Jiménez" "autores" => array:3 [ 0 => array:3 [ "nombre" => "J." "apellidos" => "Bautista Lorite" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "aff0010" ] ] ] 1 => array:3 [ "nombre" => "R." "apellidos" => "Márquez" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">**</span>" "identificador" => "aff0015" ] ] ] 2 => array:3 [ "nombre" => "L." "apellidos" => "Jiménez" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">**</span>" "identificador" => "aff0015" ] ] ] ] "afiliaciones" => array:2 [ 0 => array:3 [ "entidad" => "Servicio de Neurología. Hospital Universitario Virgen del Rocío. Sevilla" "etiqueta" => "*" "identificador" => "aff0010" ] 1 => array:3 [ "entidad" => "Departamento de Bioquímica.Hospital Universitario Virgen del Rocío. Sevilla" "etiqueta" => "**" "identificador" => "aff0015" ] ] ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Accuracy and validity of the lactic acidosis threshold in comparison with other non invasive methods of measuring the anaerobic threshold in patients with metabolic myopathies" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "1995-07-17" "fechaAceptado" => "1995-11-16" "PalabrasClave" => array:2 [ "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec546135" "palabras" => array:3 [ 0 => "Umbral anaerobio" 1 => "Miopatías metabólicas" 2 => "Test de ejercicio cardiopulmonar" ] ] ] "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key words" "identificador" => "xpalclavsec546134" "palabras" => array:3 [ 0 => "Anaerobic threshold" 1 => "Metabolic myopathies" 2 => "Cardiopulmonary exercise test" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "es" => array:2 [ "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Algunos autores encuentran una mala correlación entre los diferentes métodos de medición del umbral anaerobio (UA), e incluso variabilidad en la medición realizada por diferentes observadores para el mismo método. Desconocemos si este hecho también ocurre en pacientes con miopatías metabólicas (MM).</p></span> <span id="abst0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Objetivo</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Determinar la variabilidad intra e interobservador en la medición del UA en pacientes con MM y analizar las diferencias según el método utilizado. Realizamos prueba de esfuerzo en tapiz a 16 pacientes con diferentes MM. El UA se determinó mediante 4 métodos: umbral láctico (UL), semilog-UL, equivalente respiratorio y <span class="elsevierStyleSmallCaps">V</span>-<span class="elsevierStyleItalic">slope</span>, y fue evaluado por 2 observadores, que analizaron los gráficos ordenados de forma aleatoria, en dos ocasiones diferentes, localizando en cada gráfico el UA. El método del equivalente presentó la mejor correlación intraobservador (r’ = 0,95; p < 0,05), siendo mejor que con el método de UL (r’ = 0,68; p < 0,05). Las correlaciones interobservador fueron igualmente aceptables, excepto para el método de la <span class="elsevierStyleSmallCaps">V</span><span class="elsevierStyleItalic">-slope</span> (r’ = 0,36; p > 0,05). El hallazgo más importante en la comparación entre métodos fue la existencia de diferencias significativas en el VO<span class="elsevierStyleInf">2</span> (ml/min) en el UA entre el método del UL y los métodos no invasivos (UL = 1.066; equiv. = 1.312; p < 0,05; UL = 1.095; <span class="elsevierStyleSmallCaps">V</span><span class="elsevierStyleItalic">-slope =</span> 1.251; p < 0,05).</p></span> <span id="abst0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Conclusión</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">En los pacientes con MM la variabilidad intra e interobservador es pequeña, siendo ésta mayor con el método de la <span class="elsevierStyleSmallCaps">V</span><span class="elsevierStyleItalic">-slope.</span> Con los métodos no invasivos, el UA es de aparición más tardía, y por ello son preferibles las determinaciones invasivas (UL).</p></span>" "secciones" => array:3 [ 0 => array:1 [ "identificador" => "abst0005" ] 1 => array:2 [ "identificador" => "abst0010" "titulo" => "Objetivo" ] 2 => array:2 [ "identificador" => "abst0015" "titulo" => "Conclusión" ] ] ] "en" => array:2 [ "resumen" => "<span id="abst0020" class="elsevierStyleSection elsevierViewall"><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">Poor correlation among the various methods for measuring anaerobic threshold (AT) has been reported, and some authors have even reported interobserver variability within a single method. It is unknown whether such variability exists in patients with metabolic myopathies (MM).</p></span> <span id="abst0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0015">Objective</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">To determine intra and interobserver variability in the measurement of AT in patients with MM and analyze the differences for each method used. We enrolled 16 patients with differing forms of MM for exercise testing. AT was determined by 4 methods: lactic threshold (LT), semi-log LT, respiratory equivalent and <span class="elsevierStyleSmallCaps">V</span>-slope. AT was assessed by 2 observers, who analyzed plots in random order on 2 different occasions, locating the AT in each plot. The respiratory equivalent method gave the best intraobserver correlation (r’ = 0.95; p < 0.05) and was superior to the LT method (r’ = 0.68; p < 0.05). Interobserver correlation was equally acceptable for all except the <span class="elsevierStyleSmallCaps">V</span>-slope method (r’ = 0.36; p > 0.05). The most important finding after comparison of the methods was the significant difference in VO<span class="elsevierStyleInf">2</span> (ml/min) in AT between the LT method and the non invasive methods (LT = 1,006; respiratory equivalent 1,312; p < 0.05; LT = 1,095; <span class="elsevierStyleSmallCaps">V</span>-slope = 1,251; p < 0.05).</p></span> <span id="abst0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0020">Conclusion</span><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">Intra and interobserver variability is slight in patients with MM; the best method in this respect is that of the <span class="elsevierStyleSmallCaps">V</span>-slope. AT appears later with non invasive methods and for that reason, invasive measurement (LT) is preferable.</p></span>" "secciones" => array:3 [ 0 => array:1 [ "identificador" => "abst0020" ] 1 => array:2 [ "identificador" => "abst0025" "titulo" => "Objective" ] 2 => array:2 [ "identificador" => "abst0030" "titulo" => "Conclusion" ] ] ] ] "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "*" "nota" => "<p class="elsevierStyleNotepara" id="np0005">Este trabajo ha sido subvencionado con una beca FEPAR 1993.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "Bibliografía" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:29 [ 0 => array:3 [ "identificador" => "bib0005" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Detecting the threshold of anaerobic metabolism" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "K. Wasserman" 1 => "M.B. 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| Year/Month | Html | Total | |
|---|---|---|---|
| 2024 November | 2 | 1 | 3 |
| 2024 October | 28 | 16 | 44 |
| 2024 September | 42 | 19 | 61 |
| 2024 August | 49 | 28 | 77 |
| 2024 July | 33 | 23 | 56 |
| 2024 June | 51 | 19 | 70 |
| 2024 May | 40 | 26 | 66 |
| 2024 April | 29 | 23 | 52 |
| 2024 March | 47 | 41 | 88 |
| 2024 February | 45 | 28 | 73 |
| 2024 January | 0 | 4 | 4 |
| 2023 December | 0 | 8 | 8 |
| 2023 November | 0 | 2 | 2 |
| 2023 October | 0 | 4 | 4 |
| 2023 September | 0 | 4 | 4 |
| 2023 August | 0 | 2 | 2 |
| 2023 July | 0 | 17 | 17 |
| 2023 June | 0 | 3 | 3 |
| 2023 March | 6 | 8 | 14 |
| 2023 February | 26 | 17 | 43 |
| 2023 January | 29 | 24 | 53 |
| 2022 December | 27 | 24 | 51 |
| 2022 November | 49 | 22 | 71 |
| 2022 October | 31 | 35 | 66 |
| 2022 September | 16 | 24 | 40 |
| 2022 August | 39 | 41 | 80 |
| 2022 July | 21 | 33 | 54 |
| 2022 June | 20 | 27 | 47 |
| 2022 May | 29 | 28 | 57 |
| 2022 April | 35 | 30 | 65 |
| 2022 March | 37 | 43 | 80 |
| 2022 February | 36 | 21 | 57 |
| 2022 January | 26 | 44 | 70 |
| 2021 December | 20 | 34 | 54 |
| 2021 November | 25 | 39 | 64 |
| 2021 October | 25 | 35 | 60 |
| 2021 September | 18 | 38 | 56 |
| 2021 August | 15 | 25 | 40 |
| 2021 July | 15 | 30 | 45 |
| 2021 June | 23 | 41 | 64 |
| 2021 May | 22 | 23 | 45 |
| 2021 April | 34 | 48 | 82 |
| 2021 March | 27 | 21 | 48 |
| 2021 February | 44 | 17 | 61 |
| 2021 January | 39 | 15 | 54 |
| 2020 December | 34 | 18 | 52 |
| 2020 November | 15 | 19 | 34 |
| 2020 October | 11 | 3 | 14 |
| 2020 September | 11 | 7 | 18 |
| 2020 August | 18 | 14 | 32 |
| 2020 July | 30 | 11 | 41 |
| 2020 June | 21 | 8 | 29 |
| 2020 May | 16 | 13 | 29 |
| 2020 April | 23 | 6 | 29 |
| 2020 March | 19 | 17 | 36 |
| 2020 February | 21 | 23 | 44 |
| 2020 January | 40 | 16 | 56 |
| 2019 December | 31 | 30 | 61 |
| 2019 November | 23 | 15 | 38 |
| 2019 October | 14 | 9 | 23 |
| 2019 September | 22 | 34 | 56 |
| 2019 August | 15 | 7 | 22 |
| 2019 July | 25 | 29 | 54 |
| 2019 June | 17 | 20 | 37 |
| 2019 May | 26 | 28 | 54 |
| 2019 April | 37 | 26 | 63 |
| 2019 March | 13 | 17 | 30 |
| 2019 February | 15 | 10 | 25 |
| 2019 January | 11 | 9 | 20 |
| 2018 December | 12 | 17 | 29 |
| 2018 November | 17 | 15 | 32 |
| 2018 October | 17 | 12 | 29 |
| 2018 September | 19 | 10 | 29 |
| 2018 May | 5 | 1 | 6 |
| 2018 April | 7 | 6 | 13 |
| 2018 March | 11 | 5 | 16 |
| 2018 February | 7 | 7 | 14 |
| 2018 January | 8 | 3 | 11 |
| 2017 December | 8 | 10 | 18 |
| 2017 November | 7 | 7 | 14 |
| 2017 October | 7 | 12 | 19 |
| 2017 September | 5 | 9 | 14 |
| 2017 August | 11 | 15 | 26 |
| 2017 July | 5 | 8 | 13 |
| 2017 June | 11 | 22 | 33 |
| 2017 May | 11 | 21 | 32 |
| 2017 April | 5 | 13 | 18 |
| 2017 March | 6 | 16 | 22 |
| 2017 February | 5 | 6 | 11 |
| 2017 January | 6 | 11 | 17 |
| 2016 December | 14 | 12 | 26 |
| 2016 November | 26 | 15 | 41 |
| 2016 October | 28 | 26 | 54 |
| 2016 September | 26 | 17 | 43 |
| 2016 August | 86 | 6 | 92 |
| 2016 July | 16 | 4 | 20 |
| 2016 June | 27 | 15 | 42 |
| 2016 May | 17 | 7 | 24 |
| 2016 April | 12 | 0 | 12 |
| 2016 March | 9 | 0 | 9 |
| 2016 February | 11 | 0 | 11 |
| 2016 January | 17 | 3 | 20 |
| 2015 December | 33 | 19 | 52 |
| 2015 November | 32 | 6 | 38 |
| 2015 October | 5 | 2 | 7 |
| 2015 September | 2 | 0 | 2 |
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