array:23 [
  "pii" => "S0300289615307407"
  "issn" => "03002896"
  "doi" => "10.1016/S0300-2896(15)30740-7"
  "estado" => "S300"
  "fechaPublicacion" => "1996-08-01"
  "aid" => "70810"
  "copyright" => "Sociedad Española de Neumología y Cirugía Torácica"
  "copyrightAnyo" => "1996"
  "documento" => "article"
  "crossmark" => 0
  "subdocumento" => "fla"
  "cita" => "Arch Bronconeumol. 1996;32:348-55"
  "abierto" => array:3 [
    "ES" => true
    "ES2" => true
    "LATM" => true
  ]
  "gratuito" => true
  "lecturas" => array:2 [
    "total" => 2992
    "formatos" => array:3 [
      "EPUB" => 78
      "HTML" => 909
      "PDF" => 2005
    ]
  ]
  "itemSiguiente" => array:18 [
    "pii" => "S0300289615307419"
    "issn" => "03002896"
    "doi" => "10.1016/S0300-2896(15)30741-9"
    "estado" => "S300"
    "fechaPublicacion" => "1996-08-01"
    "aid" => "70811"
    "copyright" => "Sociedad Española de Neumología y Cirugía Torácica"
    "documento" => "article"
    "crossmark" => 0
    "subdocumento" => "fla"
    "cita" => "Arch Bronconeumol. 1996;32:357-65"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 2470
      "formatos" => array:3 [
        "EPUB" => 62
        "HTML" => 783
        "PDF" => 1625
      ]
    ]
    "es" => array:7 [
      "idiomaDefecto" => true
      "titulo" => "Nuevos fármacos en el tratamiento del asma"
      "tienePdf" => "es"
      "tieneTextoCompleto" => 0
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "357"
          "paginaFinal" => "365"
        ]
      ]
      "contienePdf" => array:1 [
        "es" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "A. de Diego Damiá"
          "autores" => array:1 [
            0 => array:2 [
              "nombre" => "A."
              "apellidos" => "de Diego Damiá"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "es"
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289615307419?idApp=UINPBA00003Z"
    "url" => "/03002896/0000003200000007/v1_201506230057/S0300289615307419/v1_201506230057/es/main.assets"
  ]
  "itemAnterior" => array:18 [
    "pii" => "S0300289615307390"
    "issn" => "03002896"
    "doi" => "10.1016/S0300-2896(15)30739-0"
    "estado" => "S300"
    "fechaPublicacion" => "1996-08-01"
    "aid" => "70809"
    "copyright" => "Sociedad Española de Neumología y Cirugía Torácica"
    "documento" => "article"
    "crossmark" => 0
    "subdocumento" => "fla"
    "cita" => "Arch Bronconeumol. 1996;32:341-7"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 1467
      "formatos" => array:3 [
        "EPUB" => 60
        "HTML" => 844
        "PDF" => 563
      ]
    ]
    "es" => array:10 [
      "idiomaDefecto" => true
      "titulo" => "Estimulación hipercápnica y respuesta ventilatoria en el síndrome de apnea obstructiva del sueño. Comparación de reinhalación y estado-estable"
      "tienePdf" => "es"
      "tieneTextoCompleto" => 0
      "tieneResumen" => array:2 [
        0 => "es"
        1 => "en"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "341"
          "paginaFinal" => "347"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "en" => array:1 [
          "titulo" => "Hypercapnic stimulation and ventilatory response in obstructive sleep apnea syndrome. Comparison of rebreathing and stable techniques"
        ]
      ]
      "contieneResumen" => array:2 [
        "es" => true
        "en" => true
      ]
      "contienePdf" => array:1 [
        "es" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "J.G. Soto Campos, S. Cano Gómez, J. Fernández Guerra, M.A. Sánchez Armengol, F. Capote Gil, J. Castillo Gómez"
          "autores" => array:6 [
            0 => array:2 [
              "nombre" => "J.G."
              "apellidos" => "Soto Campos"
            ]
            1 => array:2 [
              "nombre" => "S."
              "apellidos" => "Cano Gómez"
            ]
            2 => array:2 [
              "nombre" => "J."
              "apellidos" => "Fernández Guerra"
            ]
            3 => array:2 [
              "nombre" => "M.A."
              "apellidos" => "Sánchez Armengol"
            ]
            4 => array:2 [
              "nombre" => "F."
              "apellidos" => "Capote Gil"
            ]
            5 => array:2 [
              "nombre" => "J."
              "apellidos" => "Castillo Gómez"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "es"
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289615307390?idApp=UINPBA00003Z"
    "url" => "/03002896/0000003200000007/v1_201506230057/S0300289615307390/v1_201506230057/es/main.assets"
  ]
  "es" => array:10 [
    "idiomaDefecto" => true
    "titulo" => "Normativa de profilaxis de la enfermedad tromboembólica venosa"
    "tieneTextoCompleto" => 0
    "paginas" => array:1 [
      0 => array:2 [
        "paginaInicial" => "348"
        "paginaFinal" => "355"
      ]
    ]
    "autores" => array:1 [
      0 => array:3 [
        "autoresLista" => "J. Ruiz Manzano, R. Alberich, J. Blanquer, A. Capelastegui, M.A. Cabezudo, M.A. de Gregorio, F. Rodríguez"
        "autores" => array:8 [
          0 => array:3 [
            "nombre" => "J."
            "apellidos" => "Ruiz Manzano"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">&#42;</span>"
                "identificador" => "cor0005"
              ]
            ]
          ]
          1 => array:2 [
            "nombre" => "R&#46;"
            "apellidos" => "Alberich"
          ]
          2 => array:2 [
            "nombre" => "J&#46;"
            "apellidos" => "Blanquer"
          ]
          3 => array:2 [
            "nombre" => "A&#46;"
            "apellidos" => "Capelastegui"
          ]
          4 => array:2 [
            "nombre" => "M&#46;A&#46;"
            "apellidos" => "Cabezudo"
          ]
          5 => array:2 [
            "nombre" => "M&#46;A&#46;"
            "apellidos" => "de Gregorio"
          ]
          6 => array:2 [
            "nombre" => "F&#46;"
            "apellidos" => "Rodr&#237;guez"
          ]
          7 => array:1 [
            "colaborador" => "Grupo TEP de SEPAR"
          ]
        ]
        "correspondencia" => array:1 [
          0 => array:3 [
            "identificador" => "cor0005"
            "etiqueta" => "&#42;"
            "correspondencia" => "Correspondencia&#58; Servicio de Neumolog&#237;a&#46; Hospital Germans Trias i Pujol&#46; Ctra&#46; del Canyet&#46; Badalona&#46;"
          ]
        ]
      ]
    ]
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "fechaRecibido" => "1996-01-09"
    "fechaAceptado" => "1996-01-19"
    "bibliografia" => array:2 [
      "titulo" => "Bibliograf&#237;a"
      "seccion" => array:1 [
        0 => array:2 [
          "identificador" => "bibs0005"
          "bibliografiaReferencia" => array:60 [
            0 => array:3 [
              "identificador" => "bib0005"
              "etiqueta" => "1&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Prophylaxis of venous thromboembolism"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "A&#46;G&#46; Turpie"
                            1 => "J&#46;R&#46; Leclerc"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "LibroEditado" => array:4 [
                        "titulo" => "Venous thromboembolic disorders&#46;"
                        "paginaInicial" => "303"
                        "paginaFinal" => "345"
                        "serieFecha" => "1991"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib0010"
              "etiqueta" => "2&#46;"
              "referencia" => array:1 [
                0 => array:1 [
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:8 [
                        "titulo" => "Consensus Conference Prevention of venous thrombosis&#44; pulmonary embolism"
                        "tituloSerie" => "JAMA"
                        "fecha" => "1986"
                        "volumen" => "256"
                        "paginaInicial" => "744"
                        "paginaFinal" => "749"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3723773"
                            "web" => "Medline"
                          ]
                        ]
                        "itemHostRev" => array:3 [
                          "pii" => "S0002939404008189"
                          "estado" => "S300"
                          "issn" => "00029394"
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib0015"
              "etiqueta" => "3&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Antithrombotic therapy for venous thromboembolic disease"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "T&#46;M&#46; Hyers"
                            1 => "R&#46;D&#46; Hull"
                            2 => "J&#46;G&#46; Weg"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Chest"
                        "fecha" => "1989"
                        "volumen" => "95"
                        "numero" => "Supl"
                        "paginaInicial" => "37"
                        "paginaFinal" => "55"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib0020"
              "etiqueta" => "4&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Pr&#233;vention de la maladie thrombo-embolique"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "J&#46; Hirsh"
                            1 => "M&#46; Levine"
                            2 => "A&#46;G&#46; Turpie"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "LibroEditado" => array:4 [
                        "titulo" => "Embolie pulmonaire et thrombose veineuse profonde&#46;"
                        "paginaInicial" => "167"
                        "paginaFinal" => "183"
                        "serieFecha" => "1990"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bib0025"
              "etiqueta" => "5&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Practical approach for preventing venous thromboembolism"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "G&#46;E&#46; Roskob"
                            1 => "R&#46;D&#46; Hull"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "LibroEditado" => array:4 [
                        "titulo" => "Clinical thrombosis&#46;"
                        "paginaInicial" => "91"
                        "paginaFinal" => "106"
                        "serieFecha" => "1989"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            5 => array:3 [
              "identificador" => "bib0030"
              "etiqueta" => "6&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Anticoagulants in the prevention of venous thromboembolism"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "A&#46;S&#46; Gallus"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "En&#58; Hirsch J&#44; editores&#46; Antithrombotic therapy&#46; Bailli&#232;re&#39;s Clinical Haematology"
                        "fecha" => "1990"
                        "volumen" => "3"
                        "paginaInicial" => "651"
                        "paginaFinal" => "684"
                        "itemHostRev" => array:3 [
                          "pii" => "S0016510711022206"
                          "estado" => "S300"
                          "issn" => "00165107"
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            6 => array:3 [
              "identificador" => "bib0035"
              "etiqueta" => "7&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "A practical approach to the profilaxis of venous thromboembolism&#46; En&#58; Venous thromboembolism&#58; natural history"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "J&#46; Hirsh"
                            1 => "R&#46;D&#46; Hull"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Libro" => array:6 [
                        "titulo" => "diagnosis and management"
                        "fecha" => "1987"
                        "paginaInicial" => "117"
                        "paginaFinal" => "129"
                        "editorial" => "CRC Pres"
                        "editorialLocalizacion" => "Boca Rat&#243;n&#44; Florida"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            7 => array:3 [
              "identificador" => "bib0040"
              "etiqueta" => "8&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Prevention of venous thromboembolism in general surgical patients&#58; results of meta-analysis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "G&#46;P&#46; Clagett"
                            1 => "J&#46;S&#46; Resich"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Ann Surg"
                        "fecha" => "1988"
                        "volumen" => "208"
                        "paginaInicial" => "227"
                        "paginaFinal" => "240"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2456748"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            8 => array:3 [
              "identificador" => "bib0045"
              "etiqueta" => "9&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Prevention of venous thromboembolism"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "G&#46;P&#46; Clagett"
                            1 => "F&#46;A&#46; Anderson"
                            2 => "M&#46;K&#46; Levine"
                            3 => "E&#46;W&#46; Salzaman"
                            4 => "H&#46;B&#46; Wheeler"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "Chest"
                        "fecha" => "1992"
                        "volumen" => "102"
                        "numero" => "Supl"
                        "paginaInicial" => "391"
                        "paginaFinal" => "407"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1643920"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            9 => array:3 [
              "identificador" => "bib0050"
              "etiqueta" => "10&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Reduction in fatal pulmonary embolism and venous thrombosis by perioperative administration of subcutaneous heparin&#58; overview of results of randomized trials in general&#44; orthopaedic&#44; and urologic surgery"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "R&#46; Collins"
                            1 => "A&#46; Scrimgeour"
                            2 => "S&#46; Yusuf"
                            3 => "R&#46; Peto"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1056/NEJM198806303182602"
                      "Revista" => array:6 [
                        "tituloSerie" => "N Engl J Med"
                        "fecha" => "1988"
                        "volumen" => "318"
                        "paginaInicial" => "1&#46;162"
                        "paginaFinal" => "1&#46;173"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3287167"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            10 => array:3 [
              "identificador" => "bib0055"
              "etiqueta" => "11&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Risk of and profilaxis for venous thromboembolism in hospital patients"
                      "autores" => array:1 [
                        0 => array:2 [
                          "colaboracion" => "Thromboembolic Risk Factors Consensus Group"
                          "etal" => false
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "BMJ"
                        "fecha" => "1992"
                        "volumen" => "305"
                        "paginaInicial" => "567"
                        "paginaFinal" => "574"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1298229"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            11 => array:3 [
              "identificador" => "bib0060"
              "etiqueta" => "12&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Clinical characteristics of fatal pulmonary embolism in a referral hospital"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "T&#46;I&#46; Morgenthaler"
                            1 => "J&#46;H&#46; Ryu"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/S0025-6196(11)63876-7"
                      "Revista" => array:6 [
                        "tituloSerie" => "Mayo Clin Proc"
                        "fecha" => "1995"
                        "volumen" => "70"
                        "paginaInicial" => "417"
                        "paginaFinal" => "424"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7731250"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            12 => array:3 [
              "identificador" => "bib0065"
              "etiqueta" => "13&#46;"
              "referencia" => array:1 [
                0 => array:1 [
                  "referenciaCompleta" => "Rasmussen MS&#44; Wille-Jorgensen P&#44; Jorgensen LN&#46; Postoperative fatal pulmonary embolism in a general surgical department&#46; in press&#46;"
                ]
              ]
            ]
            13 => array:3 [
              "identificador" => "bib0070"
              "etiqueta" => "14&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The prevalence of risk factors for venous thromboembolism among hospital patients"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "F&#46;A&#46; Anderson"
                            1 => "H&#46;B&#46; Wheeler"
                            2 => "R&#46;J&#46; Goldberg"
                            3 => "D&#46;W&#46; Hosmer"
                            4 => "A&#46; Forcier"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Arch Intern Med"
                        "fecha" => "1992"
                        "volumen" => "152"
                        "paginaInicial" => "1&#46;660"
                        "paginaFinal" => "1&#46;664"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1456861"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            14 => array:3 [
              "identificador" => "bib0075"
              "etiqueta" => "15&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Deep venous thrombosis and the risk of pulmonary embolism&#46; A systematic study"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "M&#46; Monreal"
                            1 => "J&#46; Ruiz"
                            2 => "A&#46; Olaz&#225;bal"
                            3 => "A&#46; Arias"
                            4 => "J&#46; Roca"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Chest"
                        "fecha" => "1992"
                        "volumen" => "102"
                        "paginaInicial" => "677"
                        "paginaFinal" => "681"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1516386"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            15 => array:3 [
              "identificador" => "bib0080"
              "etiqueta" => "16&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Venous thromboembolism&#46; Risk factors and prophylaxis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "F&#46;A&#46; Anderson"
                            1 => "H&#46;B&#46; Wheeler"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Clin Chest Med"
                        "fecha" => "1995"
                        "volumen" => "16"
                        "paginaInicial" => "235"
                        "paginaFinal" => "251"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7656537"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            16 => array:3 [
              "identificador" => "bib0085"
              "etiqueta" => "17&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Acquired risk factors for deep vein thrombosis in symptomatic outpatients"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "A&#46; Cogo"
                            1 => "E&#46; Bernardi"
                            2 => "P&#46; Prandoni"
                            3 => "B&#46; Girolami"
                            4 => "F&#46; Noventa"
                            5 => "P&#46; Simioni"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Arch Intern Med"
                        "fecha" => "1994"
                        "volumen" => "154"
                        "paginaInicial" => "164"
                        "paginaFinal" => "168"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8285811"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            17 => array:3 [
              "identificador" => "bib0090"
              "etiqueta" => "18&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Pulmonary embolism in patients with upper extremity DVT associated to venous central lines&#58; a prospective study"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "M&#46; Monreal"
                            1 => "A&#46; Ravent&#243;s"
                            2 => "R&#46; Lerma"
                            3 => "J&#46; Ruiz"
                            4 => "E&#46; Lafoz"
                            5 => "A&#46; Alatru&#233;"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Thromb Haemost"
                        "fecha" => "1994"
                        "volumen" => "72"
                        "paginaInicial" => "548"
                        "paginaFinal" => "550"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7878630"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            18 => array:3 [
              "identificador" => "bib0095"
              "etiqueta" => "19&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Hypercoagulable state"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "R&#46;L&#46; Nachman"
                            1 => "R&#46; Silverstein"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Ann Intern Med"
                        "fecha" => "1993"
                        "volumen" => "199"
                        "paginaInicial" => "819"
                        "paginaFinal" => "823"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            19 => array:3 [
              "identificador" => "bib0100"
              "etiqueta" => "20&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Graduated compression stockings in the prevention of postoperative venous thromboembolism&#46; A metaanalysis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "P&#46;S&#46; Wells"
                            1 => "A&#46;W&#46;A&#46; Lensing"
                            2 => "J&#46; Hirsch"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Arch Intern Med"
                        "fecha" => "1994"
                        "volumen" => "154"
                        "paginaInicial" => "67"
                        "paginaFinal" => "72"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8267491"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            20 => array:3 [
              "identificador" => "bib0105"
              "etiqueta" => "21&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Heparin"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "J&#46; Hirsh"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1056/NEJM199106273242602"
                      "Revista" => array:6 [
                        "tituloSerie" => "N Engl J Med"
                        "fecha" => "1991"
                        "volumen" => "324"
                        "paginaInicial" => "1&#46;565"
                        "paginaFinal" => "1&#46;574"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2041550"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            21 => array:3 [
              "identificador" => "bib0110"
              "etiqueta" => "22&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Heparine&#58; mechanism of action&#44; pharmacokinetics&#44; dosing considerations&#44; monitoring&#44; efficacy an safety"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "J&#46; Hirsh"
                            1 => "J&#46;E&#46; Dalen"
                            2 => "D&#46; Deykin"
                            3 => "L&#46; Poller"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Chest"
                        "fecha" => "1992"
                        "volumen" => "102"
                        "numero" => "Supl"
                        "paginaInicial" => "337"
                        "paginaFinal" => "351"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            22 => array:3 [
              "identificador" => "bib0115"
              "etiqueta" => "23&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Heparin-induced thrombocytopenia in patients treated with low-molecular-weight-heparin or unfractioned heparin"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "T&#46;E&#46; Warkentin"
                            1 => "M&#46;N&#46; Levine"
                            2 => "J&#46; Hirsh"
                            3 => "P&#46; Horsewood"
                            4 => "R&#46;S&#46; Roberts"
                            5 => "M&#46; Tech"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1056/NEJM199506293322611"
                      "Revista" => array:6 [
                        "tituloSerie" => "N Engl J Med"
                        "fecha" => "1995"
                        "volumen" => "332"
                        "paginaInicial" => "1&#46;330"
                        "paginaFinal" => "1&#46;335"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7760898"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            23 => array:3 [
              "identificador" => "bib0120"
              "etiqueta" => "24&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Randomized study of adjusted versus fixed low dose heparing prophylaxis of deep vein thrombosis in hip surgery"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "D&#46;A&#46; Taberner"
                            1 => "L&#46; Poller"
                            2 => "J&#46;M&#46; Thompson"
                            3 => "G&#46; Lemon"
                            4 => "F&#46;J&#46; Weighill"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "Br J Surg"
                        "fecha" => "1989"
                        "volumen" => "76"
                        "paginaInicial" => "933"
                        "paginaFinal" => "935"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2804589"
                            "web" => "Medline"
                          ]
                        ]
                        "itemHostRev" => array:3 [
                          "pii" => "S0213911112000052"
                          "estado" => "S300"
                          "issn" => "02139111"
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            24 => array:3 [
              "identificador" => "bib0125"
              "etiqueta" => "25&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Low molecular weight heparin"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "J&#46; Hirsh"
                            1 => "M&#46;N&#46; Levine"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Blood"
                        "fecha" => "1992"
                        "volumen" => "79"
                        "paginaInicial" => "1"
                        "paginaFinal" => "17"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1309422"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            25 => array:3 [
              "identificador" => "bib0130"
              "etiqueta" => "26&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Chemical and biological heterogeneity in low molecular weight heparins&#58; implications for clinical use and standardization"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "J&#46; Fareed"
                            1 => "J&#46; Walenga"
                            2 => "D&#46; Hoppensteadt"
                            3 => "A&#46; Racanelli"
                            4 => "E&#46; Coyne"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Sem Thromb Haemost"
                        "fecha" => "1989"
                        "volumen" => "15"
                        "paginaInicial" => "440"
                        "paginaFinal" => "463"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            26 => array:3 [
              "identificador" => "bib0135"
              "etiqueta" => "27&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Clinical potential of low molecular weight heparins"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "M&#46;N&#46; Levine"
                            1 => "J&#46; Hirsh"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Bailli&#232;re&#39;s Clinical Haematology"
                        "fecha" => "1990"
                        "volumen" => "3"
                        "paginaInicial" => "545"
                        "paginaFinal" => "553"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2176904"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            27 => array:3 [
              "identificador" => "bib0140"
              "etiqueta" => "28&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Low molecular weight heparins&#58; an introduction"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "S&#46; Coccheri"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "Haemostasis"
                        "fecha" => "1990"
                        "volumen" => "20"
                        "numero" => "Supl 1"
                        "paginaInicial" => "74"
                        "paginaFinal" => "80"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1964666"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            28 => array:3 [
              "identificador" => "bib0145"
              "etiqueta" => "29&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Starting prophylaxis for venous thromboembolism postoperadvely"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "C&#46; Kearon"
                            1 => "J&#46; Hirsh"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Arch Intern Med"
                        "fecha" => "1995"
                        "volumen" => "155"
                        "paginaInicial" => "366"
                        "paginaFinal" => "372"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7848019"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            29 => array:3 [
              "identificador" => "bib0150"
              "etiqueta" => "30&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Low molecular weight heparin once daily compared with conventional low-dose heparin twice daily&#46; A prospective double-blind multicentre trial on prevention of postoperative thrombosis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "D&#46; Bergqvist"
                            1 => "U&#46;S&#46; Burmark"
                            2 => "J&#46; Frisell"
                            3 => "T&#46; Hallb&#246;&#246;k"
                            4 => "B&#46; Lindblad"
                            5 => "B&#46; Risberg"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Br J Surg"
                        "fecha" => "1986"
                        "volumen" => "73"
                        "paginaInicial" => "204"
                        "paginaFinal" => "208"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3512031"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            30 => array:3 [
              "identificador" => "bib0155"
              "etiqueta" => "31&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Low molecular weight heparin given the evening before surgery compared with conventional low-dose heparin in prevention of thrombosis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "D&#46; Bergqvist"
                            1 => "T&#46; M&#228;tzsch"
                            2 => "U&#46;S&#46; Burmark"
                            3 => "J&#46; Frisell"
                            4 => "O&#46; Guilbaud"
                            5 => "T&#46; Hallb&#246;&#246;k"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Br J Surg"
                        "fecha" => "1988"
                        "volumen" => "75"
                        "paginaInicial" => "888"
                        "paginaFinal" => "891"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2846113"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            31 => array:3 [
              "identificador" => "bib0160"
              "etiqueta" => "32&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "A randomized controlled trial of a low-molecular-weight heparin &#40;enoxiparin&#41; to prevent deep-vein thrombosis in patients undergoing elective hip surgery"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "A&#46;G&#46;G&#46; Turpie"
                            1 => "M&#46;N&#46; Levine"
                            2 => "J&#46; Hirsh"
                            3 => "C&#46;J&#46; Carter"
                            4 => "R&#46;M&#46; Jay"
                            5 => "P&#46;J&#46; Powers"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1056/NEJM198610093151503"
                      "Revista" => array:6 [
                        "tituloSerie" => "N Engl J Med"
                        "fecha" => "1986"
                        "volumen" => "315"
                        "paginaInicial" => "925"
                        "paginaFinal" => "929"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3531851"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            32 => array:3 [
              "identificador" => "bib0165"
              "etiqueta" => "33&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Prophylaxis of thromboembolism with various low-molecular-weight heparins"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "S&#46; Haas"
                            1 => "G&#46; Bl&#252;mel"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "Haemostasis"
                        "fecha" => "1988"
                        "volumen" => "18"
                        "numero" => "Supl 3"
                        "paginaInicial" => "82"
                        "paginaFinal" => "87"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2840379"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            33 => array:3 [
              "identificador" => "bib0170"
              "etiqueta" => "34&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Effectiveness and safety of the low-molecular-weigth heparin CY 216 in the prevention of fatal pulmonary embolism and thromboembolic death in general surgery"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "G&#46; Pezzuoli"
                            1 => "G&#46;G&#46; Neri"
                            2 => "P&#46;G&#46; Settembrini"
                            3 => "G&#46; Coggi"
                            4 => "N&#46; Olivari"
                            5 => "G&#46; Buzetti"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "Haemostasis"
                        "fecha" => "1990"
                        "volumen" => "20"
                        "numero" => "Supl 1"
                        "paginaInicial" => "193"
                        "paginaFinal" => "204"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2173672"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            34 => array:3 [
              "identificador" => "bib0175"
              "etiqueta" => "35&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Low-molecularweight heparin and prevention of postoperative deep vein thrombosis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "V&#46;V&#46; Kakkar"
                            1 => "B&#46; Djazaeri"
                            2 => "J&#46; Fok"
                            3 => "M&#46; Fletcher"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "BMJ"
                        "fecha" => "1982"
                        "volumen" => "284"
                        "paginaInicial" => "375"
                        "paginaFinal" => "379"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/6800465"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            35 => array:3 [
              "identificador" => "bib0180"
              "etiqueta" => "36&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Boissel J-P&#46; Low molecular weight heparin in prevention of perioperative thrombosis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "A&#46; Leizorovicz"
                            1 => "M&#46;C&#46; Haugh"
                            2 => "F&#46;-R&#46; Chapuis"
                            3 => "M&#46;M&#46; Samama"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "BMJ"
                        "fecha" => "1992"
                        "volumen" => "305"
                        "paginaInicial" => "913"
                        "paginaFinal" => "920"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1281030"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            36 => array:3 [
              "identificador" => "bib0185"
              "etiqueta" => "37&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Low-molecular-weight heparin versus standard heparin in general and orthopaedic surgery&#58; a metaanalysis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "M&#46;T&#46; Nurmohamed"
                            1 => "F&#46;R&#46; Rosendaal"
                            2 => "H&#46;R&#46; Briller"
                            3 => "E&#46; Dekker"
                            4 => "D&#46;W&#46; Hommes"
                            5 => "J&#46;P&#46; Vanderbroucke"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Lancet"
                        "fecha" => "1992"
                        "volumen" => "340"
                        "paginaInicial" => "152"
                        "paginaFinal" => "156"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1352573"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            37 => array:3 [
              "identificador" => "bib0190"
              "etiqueta" => "38&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Efficacy of low molecular weight heparins&#58; an overview"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "S&#46; Haas"
                            1 => "P&#46; Haas"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Semin Thromb Haemost"
                        "fecha" => "1993"
                        "volumen" => "19"
                        "numero" => "Supl 1"
                        "paginaInicial" => "101"
                        "paginaFinal" => "106"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            38 => array:3 [
              "identificador" => "bib0195"
              "etiqueta" => "39&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Perioperative hemorrhagic complications in patients on low molecular weight heparins"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "D&#46; Bergqvist"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "Semin Thromb Hemost"
                        "fecha" => "1993"
                        "volumen" => "19"
                        "numero" => "Supl 1"
                        "paginaInicial" => "128"
                        "paginaFinal" => "130"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8395715"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            39 => array:3 [
              "identificador" => "bib0200"
              "etiqueta" => "40&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Low molecular weight heparin started before surgery as prophylaxis against deep vein thrombosis&#58; 2&#46;500 versus 5&#46;000 Xal units in 2&#46;070 patients"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "D&#46; Bergqvist"
                            1 => "U&#46;S&#46; Burmark"
                            2 => "P&#46;A&#46; Flordal"
                            3 => "J&#46; Frisell"
                            4 => "T&#46; Hallbook"
                            5 => "M&#46; Hedberg"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Br J Surg"
                        "fecha" => "1995"
                        "volumen" => "82"
                        "paginaInicial" => "496"
                        "paginaFinal" => "501"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7613894"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            40 => array:3 [
              "identificador" => "bib0205"
              "etiqueta" => "41&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Prevention of postoperative thromboembolism with enoxaparin in general surgery&#58; a german multicenter trial"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "S&#46; Haas"
                            1 => "C&#46;W&#46; Flosbach"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "Semin Thromb Hemost"
                        "fecha" => "1993"
                        "volumen" => "19"
                        "numero" => "Supl 1"
                        "paginaInicial" => "164"
                        "paginaFinal" => "173"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8395721"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            41 => array:3 [
              "identificador" => "bib0210"
              "etiqueta" => "42&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Low molecular weight versus standard heparin for prevention of venous thromboembolism after major abdominal surgery"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "V&#46;V&#46; Kakkar"
                            1 => "A&#46;T&#46; Cohen"
                            2 => "R&#46;A&#46; Edmonson"
                            3 => "M&#46;J&#46; Phillips"
                            4 => "D&#46;J&#46; Cooper"
                            5 => "S&#46;K&#46; Das"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "Lancet"
                        "fecha" => "1993"
                        "volumen" => "341"
                        "paginaInicial" => "259"
                        "paginaFinal" => "265"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8093915"
                            "web" => "Medline"
                          ]
                        ]
                        "itemHostRev" => array:3 [
                          "pii" => "S0140673602094667"
                          "estado" => "S300"
                          "issn" => "01406736"
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            42 => array:3 [
              "identificador" => "bib0215"
              "etiqueta" => "43&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "A comparison of subcutaneous low-molecular-weight heparing with warfarin sodium for thromboembolism against deepvein thrombosis after hip or knee implantation"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "R&#46; Hull"
                            1 => "G&#46; Raskob"
                            2 => "G&#46; Pineo"
                            3 => "D&#46; Rosenbloom"
                            4 => "W&#46; Evans"
                            5 => "T&#46; Mallory"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "N Engl J Med"
                        "fecha" => "1993"
                        "volumen" => "329"
                        "paginaInicial" => "1&#46;370"
                        "paginaFinal" => "1&#46;376"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8247085"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            43 => array:3 [
              "identificador" => "bib0220"
              "etiqueta" => "44&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Very low doses of warfarin can prevent thrombosis in central venous catheters&#46; A randomized prospective trial"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "M&#46;M&#46; Bern"
                            1 => "J&#46;J&#46; Lokich"
                            2 => "S&#46;R&#46; Wallach"
                            3 => "A&#46; Bothe"
                            4 => "P&#46;N&#46; Benotti"
                            5 => "C&#46;F&#46; Arkin"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Ann Intern Med"
                        "fecha" => "1990"
                        "volumen" => "112"
                        "paginaInicial" => "423"
                        "paginaFinal" => "428"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2178534"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            44 => array:3 [
              "identificador" => "bib0225"
              "etiqueta" => "45&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Collaborative overview of randomised trials of antiplatelet therapy-III&#58; reduction in venous thrombosis and pulmonary embolism by antiplatelet prophylaxis among surgial and medical patients"
                      "autores" => array:1 [
                        0 => array:2 [
                          "colaboracion" => "Antiplatelet Trialists Collaboration"
                          "etal" => false
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "BMJ"
                        "fecha" => "1994"
                        "volumen" => "308"
                        "paginaInicial" => "235"
                        "paginaFinal" => "246"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8054013"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            45 => array:3 [
              "identificador" => "bib0230"
              "etiqueta" => "46&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Aspirin and other platelet-active drugs&#46; The relationship between dose&#44; effectiveness and side effects"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "J&#46; Hirsh"
                            1 => "J&#46;E&#46; Dalen"
                            2 => "V&#46; Fuster"
                            3 => "L&#46;B&#46; Harker"
                            4 => "E&#46;W&#46; Salzman"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "Chest"
                        "fecha" => "1992"
                        "volumen" => "102"
                        "numero" => "Supl"
                        "paginaInicial" => "327"
                        "paginaFinal" => "336"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1623790"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            46 => array:3 [
              "identificador" => "bib0235"
              "etiqueta" => "47&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Effective prevention of thromboembolic complications after total hip replacement with three different doses of recombinant hirudin&#44; CGP 39393 &#40;Revasc&#41;&#46; Ciba&#44; compared to unfractioned heparin"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "B&#46;I&#46; Eriksson"
                            1 => "P&#46; K&#228;lebo"
                            2 => "S&#46; Ekman"
                            3 => "R&#46; Kerry"
                            4 => "M&#46; Baur"
                            5 => "D&#46; Bach"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Circulation"
                        "fecha" => "1994"
                        "volumen" => "90"
                        "paginaInicial" => "3&#46;066"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7994859"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            47 => array:3 [
              "identificador" => "bib0240"
              "etiqueta" => "48&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Prophylaxis of postoperative thromboembolism with low molecular weight heparins"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "L&#46;N&#46; Jorgensen"
                            1 => "P&#46; Wille-Jorgensen"
                            2 => "O&#46; Hauch"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "Br J Surg"
                        "fecha" => "1993"
                        "volumen" => "80"
                        "paginaInicial" => "689"
                        "paginaFinal" => "704"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7687188"
                            "web" => "Medline"
                          ]
                        ]
                        "itemHostRev" => array:3 [
                          "pii" => "S0212656708000097"
                          "estado" => "S300"
                          "issn" => "02126567"
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            48 => array:3 [
              "identificador" => "bib0245"
              "etiqueta" => "49&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Throembolism in patients undergoing thoracotomy"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "S&#46; Ziomek"
                            1 => "R&#46;C&#46; Read"
                            2 => "G&#46; Tobler"
                            3 => "J&#46;E&#46; Harrell"
                            4 => "J&#46;C&#46; Gocio"
                            5 => "L&#46;M&#46; Fink"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Ann Thorac Surg"
                        "fecha" => "1993"
                        "volumen" => "56"
                        "paginaInicial" => "223"
                        "paginaFinal" => "227"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8347002"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            49 => array:3 [
              "identificador" => "bib0250"
              "etiqueta" => "50&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Prophylactic agents using venographic assessment"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "D&#46;N&#46; Mohr"
                            1 => "M&#46;D&#46; Silverstein"
                            2 => "P&#46;A&#46; Murtaugh"
                            3 => "J&#46;M&#46; Harrisob"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Arch Intern Med"
                        "fecha" => "1993"
                        "volumen" => "153"
                        "paginaInicial" => "2&#46;221"
                        "paginaFinal" => "2&#46;228"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8257254"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            50 => array:3 [
              "identificador" => "bib0255"
              "etiqueta" => "51&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Economic evaluation of standard heparing and enoxaparin for prophylaxis against deep vein thrombosis in elective hip surgery"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "M&#46; Drummond"
                            1 => "M&#46; Aristides"
                            2 => "L&#46; Davies"
                            3 => "C&#46; Forbes"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "Br J Surg"
                        "fecha" => "1994"
                        "volumen" => "81"
                        "paginaInicial" => "1&#46;742"
                        "paginaFinal" => "1&#46;746"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7827945"
                            "web" => "Medline"
                          ]
                        ]
                        "itemHostRev" => array:3 [
                          "pii" => "S0016510709026996"
                          "estado" => "S300"
                          "issn" => "00165107"
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            51 => array:3 [
              "identificador" => "bib0260"
              "etiqueta" => "52&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Prevention of deep vein thrombosis after major knee surgery&#58; a randomized&#44; double-blind trial comparing a low-molecular-weight heparin &#40;enoxaparin&#41; to placebo"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "J&#46;R&#46; Leclerc"
                            1 => "W&#46; Geerts"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Thromb Haemost"
                        "fecha" => "1992"
                        "volumen" => "67"
                        "paginaInicial" => "417"
                        "paginaFinal" => "423"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1321509"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            52 => array:3 [
              "identificador" => "bib0265"
              "etiqueta" => "53&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Deep-vein thrombosis after renal transplantation&#58; a prospective analysis of frequency and risk factors"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "D&#46; Bergqvist"
                            1 => "S&#46;E&#46; Bergentz"
                            2 => "S&#46; Bornmyr"
                            3 => "B&#46; Husberg"
                            4 => "P&#46; Konrad"
                            5 => "H&#46; Lungner"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Eur Surg Res"
                        "fecha" => "1985"
                        "volumen" => "17"
                        "paginaInicial" => "69"
                        "paginaFinal" => "74"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3884341"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            53 => array:3 [
              "identificador" => "bib0270"
              "etiqueta" => "54&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Use of antithrombotic agents during pregnancy"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "J&#46;S&#46; Ginsberg"
                            1 => "C&#46;J&#46; Hirsh"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Chest"
                        "fecha" => "1992"
                        "volumen" => "102"
                        "numero" => "Supl"
                        "paginaInicial" => "385"
                        "paginaFinal" => "390"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            54 => array:3 [
              "identificador" => "bib0275"
              "etiqueta" => "55&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Use of low molecular weight heparin in pregnancy"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "E&#46; Melissari"
                            1 => "C&#46;J&#46; Parker"
                            2 => "N&#46;V&#46; Wilson"
                            3 => "G&#46; Monte"
                            4 => "C&#46; Kanthou"
                            5 => "K&#46;D&#46; Pemberton"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "Thromb Haemost"
                        "fecha" => "1992"
                        "volumen" => "68"
                        "paginaInicial" => "652"
                        "paginaFinal" => "656"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1337628"
                            "web" => "Medline"
                          ]
                        ]
                        "itemHostRev" => array:3 [
                          "pii" => "S0886335009003654"
                          "estado" => "S300"
                          "issn" => "08863350"
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            55 => array:3 [
              "identificador" => "bib0280"
              "etiqueta" => "56&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "A prospective study of venous thromboembolism after major trauma"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "W&#46;H&#46; Geerts"
                            1 => "K&#46;I&#46; Code"
                            2 => "R&#46;M&#46; Jay"
                            3 => "E&#46; Chen"
                            4 => "J&#46;P&#46; Szalai"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1056/NEJM199412293312604"
                      "Revista" => array:6 [
                        "tituloSerie" => "N Engl J Med"
                        "fecha" => "1994"
                        "volumen" => "331"
                        "paginaInicial" => "1&#46;601"
                        "paginaFinal" => "1&#46;606"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7984195"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            56 => array:3 [
              "identificador" => "bib0285"
              "etiqueta" => "57&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Low molecular weight heparin for the prevention of thromboembolism in out patients inmobilized by plaster cast"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "U&#46; Spannagel"
                            1 => "P&#46; Kujath"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Semin Thromb Haemost"
                        "fecha" => "1993"
                        "volumen" => "19"
                        "numero" => "Supl 1"
                        "paginaInicial" => "131"
                        "paginaFinal" => "141"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            57 => array:3 [
              "identificador" => "bib0290"
              "etiqueta" => "58&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "A low-molecular-weight heparinoid compared with unfractionated heparin in the prevention of deep venous thrombosis in patients with acute ischemic stroke&#46; A randomized&#44; doubleblind study"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "A&#46;G&#46;G&#46; Turpie"
                            1 => "M&#46; Gent"
                            2 => "R&#46; C&#244;te"
                            3 => "M&#46;N&#46; Levine"
                            4 => "J&#46;S&#46; Ginsberg"
                            5 => "P&#46;J&#46; Powers"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Ann Intern Med"
                        "fecha" => "1992"
                        "volumen" => "117"
                        "paginaInicial" => "353"
                        "paginaFinal" => "357"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1503326"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            58 => array:3 [
              "identificador" => "bib0295"
              "etiqueta" => "59&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Prevention of thromboembolism after spinal word injury using low-molecular-weight heparin"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "D&#46; Green"
                            1 => "M&#46;Y&#46; Lee"
                            2 => "A&#46;C&#46; Lim"
                            3 => "J&#46;S&#46; Chmiel"
                            4 => "M&#46; Vetter"
                            5 => "T&#46; Pang"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Ann Intern Med"
                        "fecha" => "1990"
                        "volumen" => "113"
                        "paginaInicial" => "571"
                        "paginaFinal" => "574"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2169216"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            59 => array:3 [
              "identificador" => "bib0300"
              "etiqueta" => "60&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Thromboprophylaxis in malignant disease"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "A&#46;K&#46; Kakkar"
                            1 => "R&#46;C&#46;N&#46; Williamson"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Br J Surg"
                        "fecha" => "1995"
                        "volumen" => "82"
                        "paginaInicial" => "742"
                        "paginaFinal" => "745"
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "es"
  "url" => "/03002896/0000003200000007/v1_201506230057/S0300289615307407/v1_201506230057/es/main.assets"
  "Apartado" => array:4 [
    "identificador" => "9266"
    "tipo" => "SECCION"
    "es" => array:2 [
      "titulo" => "Normativa de consenso actualizado"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "es"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/03002896/0000003200000007/v1_201506230057/S0300289615307407/v1_201506230057/es/main.pdf?idApp=UINPBA00003Z&text.app=https://archbronconeumol.org/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289615307407?idApp=UINPBA00003Z"
]
Share
Journal Information

Statistics

Follow this link to access the full text of the article

Normativa de profilaxis de la enfermedad tromboembólica venosa
J. Ruiz Manzano*, R. Alberich, J. Blanquer, A. Capelastegui, M.A. Cabezudo, M.A. de Gregorio, F. Rodríguez, Grupo TEP de SEPAR
Read
5559
Times
was read the article
3451
Total PDF
2108
Total HTML
Share statistics
 array:23 [
  "pii" => "S0300289615307407"
  "issn" => "03002896"
  "doi" => "10.1016/S0300-2896(15)30740-7"
  "estado" => "S300"
  "fechaPublicacion" => "1996-08-01"
  "aid" => "70810"
  "copyright" => "Sociedad Espa&#241;ola de Neumolog&#237;a y Cirug&#237;a Tor&#225;cica"
  "copyrightAnyo" => "1996"
  "documento" => "article"
  "crossmark" => 0
  "subdocumento" => "fla"
  "cita" => "Arch Bronconeumol. 1996;32:348-55"
  "abierto" => array:3 [
    "ES" => true
    "ES2" => true
    "LATM" => true
  ]
  "gratuito" => true
  "lecturas" => array:2 [
    "total" => 2992
    "formatos" => array:3 [
      "EPUB" => 78
      "HTML" => 909
      "PDF" => 2005
    ]
  ]
  "itemSiguiente" => array:18 [
    "pii" => "S0300289615307419"
    "issn" => "03002896"
    "doi" => "10.1016/S0300-2896(15)30741-9"
    "estado" => "S300"
    "fechaPublicacion" => "1996-08-01"
    "aid" => "70811"
    "copyright" => "Sociedad Espa&#241;ola de Neumolog&#237;a y Cirug&#237;a Tor&#225;cica"
    "documento" => "article"
    "crossmark" => 0
    "subdocumento" => "fla"
    "cita" => "Arch Bronconeumol. 1996;32:357-65"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 2470
      "formatos" => array:3 [
        "EPUB" => 62
        "HTML" => 783
        "PDF" => 1625
      ]
    ]
    "es" => array:7 [
      "idiomaDefecto" => true
      "titulo" => "Nuevos f&#225;rmacos en el tratamiento del asma"
      "tienePdf" => "es"
      "tieneTextoCompleto" => 0
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "357"
          "paginaFinal" => "365"
        ]
      ]
      "contienePdf" => array:1 [
        "es" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "A&#46; de Diego Dami&#225;"
          "autores" => array:1 [
            0 => array:2 [
              "nombre" => "A&#46;"
              "apellidos" => "de Diego Dami&#225;"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "es"
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289615307419?idApp=UINPBA00003Z"
    "url" => "/03002896/0000003200000007/v1_201506230057/S0300289615307419/v1_201506230057/es/main.assets"
  ]
  "itemAnterior" => array:18 [
    "pii" => "S0300289615307390"
    "issn" => "03002896"
    "doi" => "10.1016/S0300-2896(15)30739-0"
    "estado" => "S300"
    "fechaPublicacion" => "1996-08-01"
    "aid" => "70809"
    "copyright" => "Sociedad Espa&#241;ola de Neumolog&#237;a y Cirug&#237;a Tor&#225;cica"
    "documento" => "article"
    "crossmark" => 0
    "subdocumento" => "fla"
    "cita" => "Arch Bronconeumol. 1996;32:341-7"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 1467
      "formatos" => array:3 [
        "EPUB" => 60
        "HTML" => 844
        "PDF" => 563
      ]
    ]
    "es" => array:10 [
      "idiomaDefecto" => true
      "titulo" => "Estimulaci&#243;n hiperc&#225;pnica y respuesta ventilatoria en el s&#237;ndrome de apnea obstructiva del sue&#241;o&#46; Comparaci&#243;n de reinhalaci&#243;n y estado-estable"
      "tienePdf" => "es"
      "tieneTextoCompleto" => 0
      "tieneResumen" => array:2 [
        0 => "es"
        1 => "en"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "341"
          "paginaFinal" => "347"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "en" => array:1 [
          "titulo" => "Hypercapnic stimulation and ventilatory response in obstructive sleep apnea syndrome&#46; Comparison of rebreathing and stable techniques"
        ]
      ]
      "contieneResumen" => array:2 [
        "es" => true
        "en" => true
      ]
      "contienePdf" => array:1 [
        "es" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "J&#46;G&#46; Soto Campos, S&#46; Cano G&#243;mez, J&#46; Fern&#225;ndez Guerra, M&#46;A&#46; S&#225;nchez Armengol, F&#46; Capote Gil, J&#46; Castillo G&#243;mez"
          "autores" => array:6 [
            0 => array:2 [
              "nombre" => "J&#46;G&#46;"
              "apellidos" => "Soto Campos"
            ]
            1 => array:2 [
              "nombre" => "S&#46;"
              "apellidos" => "Cano G&#243;mez"
            ]
            2 => array:2 [
              "nombre" => "J&#46;"
              "apellidos" => "Fern&#225;ndez Guerra"
            ]
            3 => array:2 [
              "nombre" => "M&#46;A&#46;"
              "apellidos" => "S&#225;nchez Armengol"
            ]
            4 => array:2 [
              "nombre" => "F&#46;"
              "apellidos" => "Capote Gil"
            ]
            5 => array:2 [
              "nombre" => "J&#46;"
              "apellidos" => "Castillo G&#243;mez"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "es"
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289615307390?idApp=UINPBA00003Z"
    "url" => "/03002896/0000003200000007/v1_201506230057/S0300289615307390/v1_201506230057/es/main.assets"
  ]
  "es" => array:10 [
    "idiomaDefecto" => true
    "titulo" => "Normativa de profilaxis de la enfermedad tromboemb&#243;lica venosa"
    "tieneTextoCompleto" => 0
    "paginas" => array:1 [
      0 => array:2 [
        "paginaInicial" => "348"
        "paginaFinal" => "355"
      ]
    ]
    "autores" => array:1 [
      0 => array:3 [
        "autoresLista" => "J&#46; Ruiz Manzano, R&#46; Alberich, J&#46; Blanquer, A&#46; Capelastegui, M&#46;A&#46; Cabezudo, M&#46;A&#46; de Gregorio, F&#46; Rodr&#237;guez"
        "autores" => array:8 [
          0 => array:3 [
            "nombre" => "J&#46;"
            "apellidos" => "Ruiz Manzano"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">&#42;</span>"
                "identificador" => "cor0005"
              ]
            ]
          ]
          1 => array:2 [
            "nombre" => "R&#46;"
            "apellidos" => "Alberich"
          ]
          2 => array:2 [
            "nombre" => "J&#46;"
            "apellidos" => "Blanquer"
          ]
          3 => array:2 [
            "nombre" => "A&#46;"
            "apellidos" => "Capelastegui"
          ]
          4 => array:2 [
            "nombre" => "M&#46;A&#46;"
            "apellidos" => "Cabezudo"
          ]
          5 => array:2 [
            "nombre" => "M&#46;A&#46;"
            "apellidos" => "de Gregorio"
          ]
          6 => array:2 [
            "nombre" => "F&#46;"
            "apellidos" => "Rodr&#237;guez"
          ]
          7 => array:1 [
            "colaborador" => "Grupo TEP de SEPAR"
          ]
        ]
        "correspondencia" => array:1 [
          0 => array:3 [
            "identificador" => "cor0005"
            "etiqueta" => "&#42;"
            "correspondencia" => "Correspondencia&#58; Servicio de Neumolog&#237;a&#46; Hospital Germans Trias i Pujol&#46; Ctra&#46; del Canyet&#46; Badalona&#46;"
          ]
        ]
      ]
    ]
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "fechaRecibido" => "1996-01-09"
    "fechaAceptado" => "1996-01-19"
    "bibliografia" => array:2 [
      "titulo" => "Bibliograf&#237;a"
      "seccion" => array:1 [
        0 => array:2 [
          "identificador" => "bibs0005"
          "bibliografiaReferencia" => array:60 [
            0 => array:3 [
              "identificador" => "bib0005"
              "etiqueta" => "1&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Prophylaxis of venous thromboembolism"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "A&#46;G&#46; Turpie"
                            1 => "J&#46;R&#46; Leclerc"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "LibroEditado" => array:4 [
                        "titulo" => "Venous thromboembolic disorders&#46;"
                        "paginaInicial" => "303"
                        "paginaFinal" => "345"
                        "serieFecha" => "1991"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib0010"
              "etiqueta" => "2&#46;"
              "referencia" => array:1 [
                0 => array:1 [
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:8 [
                        "titulo" => "Consensus Conference Prevention of venous thrombosis&#44; pulmonary embolism"
                        "tituloSerie" => "JAMA"
                        "fecha" => "1986"
                        "volumen" => "256"
                        "paginaInicial" => "744"
                        "paginaFinal" => "749"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3723773"
                            "web" => "Medline"
                          ]
                        ]
                        "itemHostRev" => array:3 [
                          "pii" => "S0002939404008189"
                          "estado" => "S300"
                          "issn" => "00029394"
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib0015"
              "etiqueta" => "3&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Antithrombotic therapy for venous thromboembolic disease"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "T&#46;M&#46; Hyers"
                            1 => "R&#46;D&#46; Hull"
                            2 => "J&#46;G&#46; Weg"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Chest"
                        "fecha" => "1989"
                        "volumen" => "95"
                        "numero" => "Supl"
                        "paginaInicial" => "37"
                        "paginaFinal" => "55"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib0020"
              "etiqueta" => "4&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Pr&#233;vention de la maladie thrombo-embolique"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "J&#46; Hirsh"
                            1 => "M&#46; Levine"
                            2 => "A&#46;G&#46; Turpie"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "LibroEditado" => array:4 [
                        "titulo" => "Embolie pulmonaire et thrombose veineuse profonde&#46;"
                        "paginaInicial" => "167"
                        "paginaFinal" => "183"
                        "serieFecha" => "1990"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bib0025"
              "etiqueta" => "5&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Practical approach for preventing venous thromboembolism"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "G&#46;E&#46; Roskob"
                            1 => "R&#46;D&#46; Hull"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "LibroEditado" => array:4 [
                        "titulo" => "Clinical thrombosis&#46;"
                        "paginaInicial" => "91"
                        "paginaFinal" => "106"
                        "serieFecha" => "1989"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            5 => array:3 [
              "identificador" => "bib0030"
              "etiqueta" => "6&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Anticoagulants in the prevention of venous thromboembolism"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "A&#46;S&#46; Gallus"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "En&#58; Hirsch J&#44; editores&#46; Antithrombotic therapy&#46; Bailli&#232;re&#39;s Clinical Haematology"
                        "fecha" => "1990"
                        "volumen" => "3"
                        "paginaInicial" => "651"
                        "paginaFinal" => "684"
                        "itemHostRev" => array:3 [
                          "pii" => "S0016510711022206"
                          "estado" => "S300"
                          "issn" => "00165107"
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            6 => array:3 [
              "identificador" => "bib0035"
              "etiqueta" => "7&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "A practical approach to the profilaxis of venous thromboembolism&#46; En&#58; Venous thromboembolism&#58; natural history"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "J&#46; Hirsh"
                            1 => "R&#46;D&#46; Hull"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Libro" => array:6 [
                        "titulo" => "diagnosis and management"
                        "fecha" => "1987"
                        "paginaInicial" => "117"
                        "paginaFinal" => "129"
                        "editorial" => "CRC Pres"
                        "editorialLocalizacion" => "Boca Rat&#243;n&#44; Florida"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            7 => array:3 [
              "identificador" => "bib0040"
              "etiqueta" => "8&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Prevention of venous thromboembolism in general surgical patients&#58; results of meta-analysis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "G&#46;P&#46; Clagett"
                            1 => "J&#46;S&#46; Resich"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Ann Surg"
                        "fecha" => "1988"
                        "volumen" => "208"
                        "paginaInicial" => "227"
                        "paginaFinal" => "240"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2456748"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            8 => array:3 [
              "identificador" => "bib0045"
              "etiqueta" => "9&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Prevention of venous thromboembolism"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "G&#46;P&#46; Clagett"
                            1 => "F&#46;A&#46; Anderson"
                            2 => "M&#46;K&#46; Levine"
                            3 => "E&#46;W&#46; Salzaman"
                            4 => "H&#46;B&#46; Wheeler"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "Chest"
                        "fecha" => "1992"
                        "volumen" => "102"
                        "numero" => "Supl"
                        "paginaInicial" => "391"
                        "paginaFinal" => "407"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1643920"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            9 => array:3 [
              "identificador" => "bib0050"
              "etiqueta" => "10&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Reduction in fatal pulmonary embolism and venous thrombosis by perioperative administration of subcutaneous heparin&#58; overview of results of randomized trials in general&#44; orthopaedic&#44; and urologic surgery"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "R&#46; Collins"
                            1 => "A&#46; Scrimgeour"
                            2 => "S&#46; Yusuf"
                            3 => "R&#46; Peto"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1056/NEJM198806303182602"
                      "Revista" => array:6 [
                        "tituloSerie" => "N Engl J Med"
                        "fecha" => "1988"
                        "volumen" => "318"
                        "paginaInicial" => "1&#46;162"
                        "paginaFinal" => "1&#46;173"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3287167"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            10 => array:3 [
              "identificador" => "bib0055"
              "etiqueta" => "11&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Risk of and profilaxis for venous thromboembolism in hospital patients"
                      "autores" => array:1 [
                        0 => array:2 [
                          "colaboracion" => "Thromboembolic Risk Factors Consensus Group"
                          "etal" => false
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "BMJ"
                        "fecha" => "1992"
                        "volumen" => "305"
                        "paginaInicial" => "567"
                        "paginaFinal" => "574"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1298229"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            11 => array:3 [
              "identificador" => "bib0060"
              "etiqueta" => "12&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Clinical characteristics of fatal pulmonary embolism in a referral hospital"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "T&#46;I&#46; Morgenthaler"
                            1 => "J&#46;H&#46; Ryu"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/S0025-6196(11)63876-7"
                      "Revista" => array:6 [
                        "tituloSerie" => "Mayo Clin Proc"
                        "fecha" => "1995"
                        "volumen" => "70"
                        "paginaInicial" => "417"
                        "paginaFinal" => "424"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7731250"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            12 => array:3 [
              "identificador" => "bib0065"
              "etiqueta" => "13&#46;"
              "referencia" => array:1 [
                0 => array:1 [
                  "referenciaCompleta" => "Rasmussen MS&#44; Wille-Jorgensen P&#44; Jorgensen LN&#46; Postoperative fatal pulmonary embolism in a general surgical department&#46; in press&#46;"
                ]
              ]
            ]
            13 => array:3 [
              "identificador" => "bib0070"
              "etiqueta" => "14&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The prevalence of risk factors for venous thromboembolism among hospital patients"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "F&#46;A&#46; Anderson"
                            1 => "H&#46;B&#46; Wheeler"
                            2 => "R&#46;J&#46; Goldberg"
                            3 => "D&#46;W&#46; Hosmer"
                            4 => "A&#46; Forcier"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Arch Intern Med"
                        "fecha" => "1992"
                        "volumen" => "152"
                        "paginaInicial" => "1&#46;660"
                        "paginaFinal" => "1&#46;664"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1456861"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            14 => array:3 [
              "identificador" => "bib0075"
              "etiqueta" => "15&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Deep venous thrombosis and the risk of pulmonary embolism&#46; A systematic study"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "M&#46; Monreal"
                            1 => "J&#46; Ruiz"
                            2 => "A&#46; Olaz&#225;bal"
                            3 => "A&#46; Arias"
                            4 => "J&#46; Roca"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Chest"
                        "fecha" => "1992"
                        "volumen" => "102"
                        "paginaInicial" => "677"
                        "paginaFinal" => "681"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1516386"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            15 => array:3 [
              "identificador" => "bib0080"
              "etiqueta" => "16&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Venous thromboembolism&#46; Risk factors and prophylaxis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "F&#46;A&#46; Anderson"
                            1 => "H&#46;B&#46; Wheeler"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Clin Chest Med"
                        "fecha" => "1995"
                        "volumen" => "16"
                        "paginaInicial" => "235"
                        "paginaFinal" => "251"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7656537"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            16 => array:3 [
              "identificador" => "bib0085"
              "etiqueta" => "17&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Acquired risk factors for deep vein thrombosis in symptomatic outpatients"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "A&#46; Cogo"
                            1 => "E&#46; Bernardi"
                            2 => "P&#46; Prandoni"
                            3 => "B&#46; Girolami"
                            4 => "F&#46; Noventa"
                            5 => "P&#46; Simioni"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Arch Intern Med"
                        "fecha" => "1994"
                        "volumen" => "154"
                        "paginaInicial" => "164"
                        "paginaFinal" => "168"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8285811"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            17 => array:3 [
              "identificador" => "bib0090"
              "etiqueta" => "18&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Pulmonary embolism in patients with upper extremity DVT associated to venous central lines&#58; a prospective study"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "M&#46; Monreal"
                            1 => "A&#46; Ravent&#243;s"
                            2 => "R&#46; Lerma"
                            3 => "J&#46; Ruiz"
                            4 => "E&#46; Lafoz"
                            5 => "A&#46; Alatru&#233;"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Thromb Haemost"
                        "fecha" => "1994"
                        "volumen" => "72"
                        "paginaInicial" => "548"
                        "paginaFinal" => "550"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7878630"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            18 => array:3 [
              "identificador" => "bib0095"
              "etiqueta" => "19&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Hypercoagulable state"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "R&#46;L&#46; Nachman"
                            1 => "R&#46; Silverstein"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Ann Intern Med"
                        "fecha" => "1993"
                        "volumen" => "199"
                        "paginaInicial" => "819"
                        "paginaFinal" => "823"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            19 => array:3 [
              "identificador" => "bib0100"
              "etiqueta" => "20&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Graduated compression stockings in the prevention of postoperative venous thromboembolism&#46; A metaanalysis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "P&#46;S&#46; Wells"
                            1 => "A&#46;W&#46;A&#46; Lensing"
                            2 => "J&#46; Hirsch"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Arch Intern Med"
                        "fecha" => "1994"
                        "volumen" => "154"
                        "paginaInicial" => "67"
                        "paginaFinal" => "72"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8267491"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            20 => array:3 [
              "identificador" => "bib0105"
              "etiqueta" => "21&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Heparin"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "J&#46; Hirsh"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1056/NEJM199106273242602"
                      "Revista" => array:6 [
                        "tituloSerie" => "N Engl J Med"
                        "fecha" => "1991"
                        "volumen" => "324"
                        "paginaInicial" => "1&#46;565"
                        "paginaFinal" => "1&#46;574"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2041550"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            21 => array:3 [
              "identificador" => "bib0110"
              "etiqueta" => "22&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Heparine&#58; mechanism of action&#44; pharmacokinetics&#44; dosing considerations&#44; monitoring&#44; efficacy an safety"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "J&#46; Hirsh"
                            1 => "J&#46;E&#46; Dalen"
                            2 => "D&#46; Deykin"
                            3 => "L&#46; Poller"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Chest"
                        "fecha" => "1992"
                        "volumen" => "102"
                        "numero" => "Supl"
                        "paginaInicial" => "337"
                        "paginaFinal" => "351"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            22 => array:3 [
              "identificador" => "bib0115"
              "etiqueta" => "23&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Heparin-induced thrombocytopenia in patients treated with low-molecular-weight-heparin or unfractioned heparin"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "T&#46;E&#46; Warkentin"
                            1 => "M&#46;N&#46; Levine"
                            2 => "J&#46; Hirsh"
                            3 => "P&#46; Horsewood"
                            4 => "R&#46;S&#46; Roberts"
                            5 => "M&#46; Tech"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1056/NEJM199506293322611"
                      "Revista" => array:6 [
                        "tituloSerie" => "N Engl J Med"
                        "fecha" => "1995"
                        "volumen" => "332"
                        "paginaInicial" => "1&#46;330"
                        "paginaFinal" => "1&#46;335"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7760898"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            23 => array:3 [
              "identificador" => "bib0120"
              "etiqueta" => "24&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Randomized study of adjusted versus fixed low dose heparing prophylaxis of deep vein thrombosis in hip surgery"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "D&#46;A&#46; Taberner"
                            1 => "L&#46; Poller"
                            2 => "J&#46;M&#46; Thompson"
                            3 => "G&#46; Lemon"
                            4 => "F&#46;J&#46; Weighill"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "Br J Surg"
                        "fecha" => "1989"
                        "volumen" => "76"
                        "paginaInicial" => "933"
                        "paginaFinal" => "935"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2804589"
                            "web" => "Medline"
                          ]
                        ]
                        "itemHostRev" => array:3 [
                          "pii" => "S0213911112000052"
                          "estado" => "S300"
                          "issn" => "02139111"
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            24 => array:3 [
              "identificador" => "bib0125"
              "etiqueta" => "25&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Low molecular weight heparin"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "J&#46; Hirsh"
                            1 => "M&#46;N&#46; Levine"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Blood"
                        "fecha" => "1992"
                        "volumen" => "79"
                        "paginaInicial" => "1"
                        "paginaFinal" => "17"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1309422"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            25 => array:3 [
              "identificador" => "bib0130"
              "etiqueta" => "26&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Chemical and biological heterogeneity in low molecular weight heparins&#58; implications for clinical use and standardization"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "J&#46; Fareed"
                            1 => "J&#46; Walenga"
                            2 => "D&#46; Hoppensteadt"
                            3 => "A&#46; Racanelli"
                            4 => "E&#46; Coyne"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Sem Thromb Haemost"
                        "fecha" => "1989"
                        "volumen" => "15"
                        "paginaInicial" => "440"
                        "paginaFinal" => "463"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            26 => array:3 [
              "identificador" => "bib0135"
              "etiqueta" => "27&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Clinical potential of low molecular weight heparins"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "M&#46;N&#46; Levine"
                            1 => "J&#46; Hirsh"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Bailli&#232;re&#39;s Clinical Haematology"
                        "fecha" => "1990"
                        "volumen" => "3"
                        "paginaInicial" => "545"
                        "paginaFinal" => "553"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2176904"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            27 => array:3 [
              "identificador" => "bib0140"
              "etiqueta" => "28&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Low molecular weight heparins&#58; an introduction"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "S&#46; Coccheri"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "Haemostasis"
                        "fecha" => "1990"
                        "volumen" => "20"
                        "numero" => "Supl 1"
                        "paginaInicial" => "74"
                        "paginaFinal" => "80"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1964666"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            28 => array:3 [
              "identificador" => "bib0145"
              "etiqueta" => "29&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Starting prophylaxis for venous thromboembolism postoperadvely"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "C&#46; Kearon"
                            1 => "J&#46; Hirsh"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Arch Intern Med"
                        "fecha" => "1995"
                        "volumen" => "155"
                        "paginaInicial" => "366"
                        "paginaFinal" => "372"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7848019"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            29 => array:3 [
              "identificador" => "bib0150"
              "etiqueta" => "30&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Low molecular weight heparin once daily compared with conventional low-dose heparin twice daily&#46; A prospective double-blind multicentre trial on prevention of postoperative thrombosis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "D&#46; Bergqvist"
                            1 => "U&#46;S&#46; Burmark"
                            2 => "J&#46; Frisell"
                            3 => "T&#46; Hallb&#246;&#246;k"
                            4 => "B&#46; Lindblad"
                            5 => "B&#46; Risberg"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Br J Surg"
                        "fecha" => "1986"
                        "volumen" => "73"
                        "paginaInicial" => "204"
                        "paginaFinal" => "208"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3512031"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            30 => array:3 [
              "identificador" => "bib0155"
              "etiqueta" => "31&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Low molecular weight heparin given the evening before surgery compared with conventional low-dose heparin in prevention of thrombosis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "D&#46; Bergqvist"
                            1 => "T&#46; M&#228;tzsch"
                            2 => "U&#46;S&#46; Burmark"
                            3 => "J&#46; Frisell"
                            4 => "O&#46; Guilbaud"
                            5 => "T&#46; Hallb&#246;&#246;k"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Br J Surg"
                        "fecha" => "1988"
                        "volumen" => "75"
                        "paginaInicial" => "888"
                        "paginaFinal" => "891"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2846113"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            31 => array:3 [
              "identificador" => "bib0160"
              "etiqueta" => "32&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "A randomized controlled trial of a low-molecular-weight heparin &#40;enoxiparin&#41; to prevent deep-vein thrombosis in patients undergoing elective hip surgery"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "A&#46;G&#46;G&#46; Turpie"
                            1 => "M&#46;N&#46; Levine"
                            2 => "J&#46; Hirsh"
                            3 => "C&#46;J&#46; Carter"
                            4 => "R&#46;M&#46; Jay"
                            5 => "P&#46;J&#46; Powers"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1056/NEJM198610093151503"
                      "Revista" => array:6 [
                        "tituloSerie" => "N Engl J Med"
                        "fecha" => "1986"
                        "volumen" => "315"
                        "paginaInicial" => "925"
                        "paginaFinal" => "929"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3531851"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            32 => array:3 [
              "identificador" => "bib0165"
              "etiqueta" => "33&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Prophylaxis of thromboembolism with various low-molecular-weight heparins"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "S&#46; Haas"
                            1 => "G&#46; Bl&#252;mel"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "Haemostasis"
                        "fecha" => "1988"
                        "volumen" => "18"
                        "numero" => "Supl 3"
                        "paginaInicial" => "82"
                        "paginaFinal" => "87"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2840379"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            33 => array:3 [
              "identificador" => "bib0170"
              "etiqueta" => "34&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Effectiveness and safety of the low-molecular-weigth heparin CY 216 in the prevention of fatal pulmonary embolism and thromboembolic death in general surgery"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "G&#46; Pezzuoli"
                            1 => "G&#46;G&#46; Neri"
                            2 => "P&#46;G&#46; Settembrini"
                            3 => "G&#46; Coggi"
                            4 => "N&#46; Olivari"
                            5 => "G&#46; Buzetti"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "Haemostasis"
                        "fecha" => "1990"
                        "volumen" => "20"
                        "numero" => "Supl 1"
                        "paginaInicial" => "193"
                        "paginaFinal" => "204"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2173672"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            34 => array:3 [
              "identificador" => "bib0175"
              "etiqueta" => "35&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Low-molecularweight heparin and prevention of postoperative deep vein thrombosis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "V&#46;V&#46; Kakkar"
                            1 => "B&#46; Djazaeri"
                            2 => "J&#46; Fok"
                            3 => "M&#46; Fletcher"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "BMJ"
                        "fecha" => "1982"
                        "volumen" => "284"
                        "paginaInicial" => "375"
                        "paginaFinal" => "379"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/6800465"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            35 => array:3 [
              "identificador" => "bib0180"
              "etiqueta" => "36&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Boissel J-P&#46; Low molecular weight heparin in prevention of perioperative thrombosis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "A&#46; Leizorovicz"
                            1 => "M&#46;C&#46; Haugh"
                            2 => "F&#46;-R&#46; Chapuis"
                            3 => "M&#46;M&#46; Samama"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "BMJ"
                        "fecha" => "1992"
                        "volumen" => "305"
                        "paginaInicial" => "913"
                        "paginaFinal" => "920"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1281030"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            36 => array:3 [
              "identificador" => "bib0185"
              "etiqueta" => "37&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Low-molecular-weight heparin versus standard heparin in general and orthopaedic surgery&#58; a metaanalysis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "M&#46;T&#46; Nurmohamed"
                            1 => "F&#46;R&#46; Rosendaal"
                            2 => "H&#46;R&#46; Briller"
                            3 => "E&#46; Dekker"
                            4 => "D&#46;W&#46; Hommes"
                            5 => "J&#46;P&#46; Vanderbroucke"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Lancet"
                        "fecha" => "1992"
                        "volumen" => "340"
                        "paginaInicial" => "152"
                        "paginaFinal" => "156"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1352573"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            37 => array:3 [
              "identificador" => "bib0190"
              "etiqueta" => "38&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Efficacy of low molecular weight heparins&#58; an overview"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "S&#46; Haas"
                            1 => "P&#46; Haas"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Semin Thromb Haemost"
                        "fecha" => "1993"
                        "volumen" => "19"
                        "numero" => "Supl 1"
                        "paginaInicial" => "101"
                        "paginaFinal" => "106"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            38 => array:3 [
              "identificador" => "bib0195"
              "etiqueta" => "39&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Perioperative hemorrhagic complications in patients on low molecular weight heparins"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "D&#46; Bergqvist"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "Semin Thromb Hemost"
                        "fecha" => "1993"
                        "volumen" => "19"
                        "numero" => "Supl 1"
                        "paginaInicial" => "128"
                        "paginaFinal" => "130"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8395715"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            39 => array:3 [
              "identificador" => "bib0200"
              "etiqueta" => "40&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Low molecular weight heparin started before surgery as prophylaxis against deep vein thrombosis&#58; 2&#46;500 versus 5&#46;000 Xal units in 2&#46;070 patients"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "D&#46; Bergqvist"
                            1 => "U&#46;S&#46; Burmark"
                            2 => "P&#46;A&#46; Flordal"
                            3 => "J&#46; Frisell"
                            4 => "T&#46; Hallbook"
                            5 => "M&#46; Hedberg"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Br J Surg"
                        "fecha" => "1995"
                        "volumen" => "82"
                        "paginaInicial" => "496"
                        "paginaFinal" => "501"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7613894"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            40 => array:3 [
              "identificador" => "bib0205"
              "etiqueta" => "41&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Prevention of postoperative thromboembolism with enoxaparin in general surgery&#58; a german multicenter trial"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "S&#46; Haas"
                            1 => "C&#46;W&#46; Flosbach"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "Semin Thromb Hemost"
                        "fecha" => "1993"
                        "volumen" => "19"
                        "numero" => "Supl 1"
                        "paginaInicial" => "164"
                        "paginaFinal" => "173"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8395721"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            41 => array:3 [
              "identificador" => "bib0210"
              "etiqueta" => "42&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Low molecular weight versus standard heparin for prevention of venous thromboembolism after major abdominal surgery"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "V&#46;V&#46; Kakkar"
                            1 => "A&#46;T&#46; Cohen"
                            2 => "R&#46;A&#46; Edmonson"
                            3 => "M&#46;J&#46; Phillips"
                            4 => "D&#46;J&#46; Cooper"
                            5 => "S&#46;K&#46; Das"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "Lancet"
                        "fecha" => "1993"
                        "volumen" => "341"
                        "paginaInicial" => "259"
                        "paginaFinal" => "265"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8093915"
                            "web" => "Medline"
                          ]
                        ]
                        "itemHostRev" => array:3 [
                          "pii" => "S0140673602094667"
                          "estado" => "S300"
                          "issn" => "01406736"
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            42 => array:3 [
              "identificador" => "bib0215"
              "etiqueta" => "43&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "A comparison of subcutaneous low-molecular-weight heparing with warfarin sodium for thromboembolism against deepvein thrombosis after hip or knee implantation"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "R&#46; Hull"
                            1 => "G&#46; Raskob"
                            2 => "G&#46; Pineo"
                            3 => "D&#46; Rosenbloom"
                            4 => "W&#46; Evans"
                            5 => "T&#46; Mallory"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "N Engl J Med"
                        "fecha" => "1993"
                        "volumen" => "329"
                        "paginaInicial" => "1&#46;370"
                        "paginaFinal" => "1&#46;376"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8247085"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            43 => array:3 [
              "identificador" => "bib0220"
              "etiqueta" => "44&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Very low doses of warfarin can prevent thrombosis in central venous catheters&#46; A randomized prospective trial"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "M&#46;M&#46; Bern"
                            1 => "J&#46;J&#46; Lokich"
                            2 => "S&#46;R&#46; Wallach"
                            3 => "A&#46; Bothe"
                            4 => "P&#46;N&#46; Benotti"
                            5 => "C&#46;F&#46; Arkin"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Ann Intern Med"
                        "fecha" => "1990"
                        "volumen" => "112"
                        "paginaInicial" => "423"
                        "paginaFinal" => "428"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2178534"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            44 => array:3 [
              "identificador" => "bib0225"
              "etiqueta" => "45&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Collaborative overview of randomised trials of antiplatelet therapy-III&#58; reduction in venous thrombosis and pulmonary embolism by antiplatelet prophylaxis among surgial and medical patients"
                      "autores" => array:1 [
                        0 => array:2 [
                          "colaboracion" => "Antiplatelet Trialists Collaboration"
                          "etal" => false
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "BMJ"
                        "fecha" => "1994"
                        "volumen" => "308"
                        "paginaInicial" => "235"
                        "paginaFinal" => "246"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8054013"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            45 => array:3 [
              "identificador" => "bib0230"
              "etiqueta" => "46&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Aspirin and other platelet-active drugs&#46; The relationship between dose&#44; effectiveness and side effects"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "J&#46; Hirsh"
                            1 => "J&#46;E&#46; Dalen"
                            2 => "V&#46; Fuster"
                            3 => "L&#46;B&#46; Harker"
                            4 => "E&#46;W&#46; Salzman"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "Chest"
                        "fecha" => "1992"
                        "volumen" => "102"
                        "numero" => "Supl"
                        "paginaInicial" => "327"
                        "paginaFinal" => "336"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1623790"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            46 => array:3 [
              "identificador" => "bib0235"
              "etiqueta" => "47&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Effective prevention of thromboembolic complications after total hip replacement with three different doses of recombinant hirudin&#44; CGP 39393 &#40;Revasc&#41;&#46; Ciba&#44; compared to unfractioned heparin"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "B&#46;I&#46; Eriksson"
                            1 => "P&#46; K&#228;lebo"
                            2 => "S&#46; Ekman"
                            3 => "R&#46; Kerry"
                            4 => "M&#46; Baur"
                            5 => "D&#46; Bach"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Circulation"
                        "fecha" => "1994"
                        "volumen" => "90"
                        "paginaInicial" => "3&#46;066"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7994859"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            47 => array:3 [
              "identificador" => "bib0240"
              "etiqueta" => "48&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Prophylaxis of postoperative thromboembolism with low molecular weight heparins"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "L&#46;N&#46; Jorgensen"
                            1 => "P&#46; Wille-Jorgensen"
                            2 => "O&#46; Hauch"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "Br J Surg"
                        "fecha" => "1993"
                        "volumen" => "80"
                        "paginaInicial" => "689"
                        "paginaFinal" => "704"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7687188"
                            "web" => "Medline"
                          ]
                        ]
                        "itemHostRev" => array:3 [
                          "pii" => "S0212656708000097"
                          "estado" => "S300"
                          "issn" => "02126567"
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            48 => array:3 [
              "identificador" => "bib0245"
              "etiqueta" => "49&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Throembolism in patients undergoing thoracotomy"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "S&#46; Ziomek"
                            1 => "R&#46;C&#46; Read"
                            2 => "G&#46; Tobler"
                            3 => "J&#46;E&#46; Harrell"
                            4 => "J&#46;C&#46; Gocio"
                            5 => "L&#46;M&#46; Fink"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Ann Thorac Surg"
                        "fecha" => "1993"
                        "volumen" => "56"
                        "paginaInicial" => "223"
                        "paginaFinal" => "227"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8347002"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            49 => array:3 [
              "identificador" => "bib0250"
              "etiqueta" => "50&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Prophylactic agents using venographic assessment"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "D&#46;N&#46; Mohr"
                            1 => "M&#46;D&#46; Silverstein"
                            2 => "P&#46;A&#46; Murtaugh"
                            3 => "J&#46;M&#46; Harrisob"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Arch Intern Med"
                        "fecha" => "1993"
                        "volumen" => "153"
                        "paginaInicial" => "2&#46;221"
                        "paginaFinal" => "2&#46;228"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8257254"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            50 => array:3 [
              "identificador" => "bib0255"
              "etiqueta" => "51&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Economic evaluation of standard heparing and enoxaparin for prophylaxis against deep vein thrombosis in elective hip surgery"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "M&#46; Drummond"
                            1 => "M&#46; Aristides"
                            2 => "L&#46; Davies"
                            3 => "C&#46; Forbes"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "Br J Surg"
                        "fecha" => "1994"
                        "volumen" => "81"
                        "paginaInicial" => "1&#46;742"
                        "paginaFinal" => "1&#46;746"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7827945"
                            "web" => "Medline"
                          ]
                        ]
                        "itemHostRev" => array:3 [
                          "pii" => "S0016510709026996"
                          "estado" => "S300"
                          "issn" => "00165107"
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            51 => array:3 [
              "identificador" => "bib0260"
              "etiqueta" => "52&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Prevention of deep vein thrombosis after major knee surgery&#58; a randomized&#44; double-blind trial comparing a low-molecular-weight heparin &#40;enoxaparin&#41; to placebo"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "J&#46;R&#46; Leclerc"
                            1 => "W&#46; Geerts"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Thromb Haemost"
                        "fecha" => "1992"
                        "volumen" => "67"
                        "paginaInicial" => "417"
                        "paginaFinal" => "423"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1321509"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            52 => array:3 [
              "identificador" => "bib0265"
              "etiqueta" => "53&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Deep-vein thrombosis after renal transplantation&#58; a prospective analysis of frequency and risk factors"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "D&#46; Bergqvist"
                            1 => "S&#46;E&#46; Bergentz"
                            2 => "S&#46; Bornmyr"
                            3 => "B&#46; Husberg"
                            4 => "P&#46; Konrad"
                            5 => "H&#46; Lungner"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Eur Surg Res"
                        "fecha" => "1985"
                        "volumen" => "17"
                        "paginaInicial" => "69"
                        "paginaFinal" => "74"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3884341"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            53 => array:3 [
              "identificador" => "bib0270"
              "etiqueta" => "54&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Use of antithrombotic agents during pregnancy"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "J&#46;S&#46; Ginsberg"
                            1 => "C&#46;J&#46; Hirsh"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Chest"
                        "fecha" => "1992"
                        "volumen" => "102"
                        "numero" => "Supl"
                        "paginaInicial" => "385"
                        "paginaFinal" => "390"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            54 => array:3 [
              "identificador" => "bib0275"
              "etiqueta" => "55&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Use of low molecular weight heparin in pregnancy"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "E&#46; Melissari"
                            1 => "C&#46;J&#46; Parker"
                            2 => "N&#46;V&#46; Wilson"
                            3 => "G&#46; Monte"
                            4 => "C&#46; Kanthou"
                            5 => "K&#46;D&#46; Pemberton"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "Thromb Haemost"
                        "fecha" => "1992"
                        "volumen" => "68"
                        "paginaInicial" => "652"
                        "paginaFinal" => "656"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1337628"
                            "web" => "Medline"
                          ]
                        ]
                        "itemHostRev" => array:3 [
                          "pii" => "S0886335009003654"
                          "estado" => "S300"
                          "issn" => "08863350"
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            55 => array:3 [
              "identificador" => "bib0280"
              "etiqueta" => "56&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "A prospective study of venous thromboembolism after major trauma"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "W&#46;H&#46; Geerts"
                            1 => "K&#46;I&#46; Code"
                            2 => "R&#46;M&#46; Jay"
                            3 => "E&#46; Chen"
                            4 => "J&#46;P&#46; Szalai"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1056/NEJM199412293312604"
                      "Revista" => array:6 [
                        "tituloSerie" => "N Engl J Med"
                        "fecha" => "1994"
                        "volumen" => "331"
                        "paginaInicial" => "1&#46;601"
                        "paginaFinal" => "1&#46;606"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7984195"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            56 => array:3 [
              "identificador" => "bib0285"
              "etiqueta" => "57&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Low molecular weight heparin for the prevention of thromboembolism in out patients inmobilized by plaster cast"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "U&#46; Spannagel"
                            1 => "P&#46; Kujath"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Semin Thromb Haemost"
                        "fecha" => "1993"
                        "volumen" => "19"
                        "numero" => "Supl 1"
                        "paginaInicial" => "131"
                        "paginaFinal" => "141"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            57 => array:3 [
              "identificador" => "bib0290"
              "etiqueta" => "58&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "A low-molecular-weight heparinoid compared with unfractionated heparin in the prevention of deep venous thrombosis in patients with acute ischemic stroke&#46; A randomized&#44; doubleblind study"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "A&#46;G&#46;G&#46; Turpie"
                            1 => "M&#46; Gent"
                            2 => "R&#46; C&#244;te"
                            3 => "M&#46;N&#46; Levine"
                            4 => "J&#46;S&#46; Ginsberg"
                            5 => "P&#46;J&#46; Powers"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Ann Intern Med"
                        "fecha" => "1992"
                        "volumen" => "117"
                        "paginaInicial" => "353"
                        "paginaFinal" => "357"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1503326"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            58 => array:3 [
              "identificador" => "bib0295"
              "etiqueta" => "59&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Prevention of thromboembolism after spinal word injury using low-molecular-weight heparin"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "D&#46; Green"
                            1 => "M&#46;Y&#46; Lee"
                            2 => "A&#46;C&#46; Lim"
                            3 => "J&#46;S&#46; Chmiel"
                            4 => "M&#46; Vetter"
                            5 => "T&#46; Pang"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Ann Intern Med"
                        "fecha" => "1990"
                        "volumen" => "113"
                        "paginaInicial" => "571"
                        "paginaFinal" => "574"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2169216"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            59 => array:3 [
              "identificador" => "bib0300"
              "etiqueta" => "60&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Thromboprophylaxis in malignant disease"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "A&#46;K&#46; Kakkar"
                            1 => "R&#46;C&#46;N&#46; Williamson"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Br J Surg"
                        "fecha" => "1995"
                        "volumen" => "82"
                        "paginaInicial" => "742"
                        "paginaFinal" => "745"
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "es"
  "url" => "/03002896/0000003200000007/v1_201506230057/S0300289615307407/v1_201506230057/es/main.assets"
  "Apartado" => array:4 [
    "identificador" => "9266"
    "tipo" => "SECCION"
    "es" => array:2 [
      "titulo" => "Normativa de consenso actualizado"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "es"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/03002896/0000003200000007/v1_201506230057/S0300289615307407/v1_201506230057/es/main.pdf?idApp=UINPBA00003Z&text.app=https://archbronconeumol.org/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289615307407?idApp=UINPBA00003Z"
]
Article information
ISSN: 03002896
Original language: Spanish
The statistics are updated each day
Year/Month Html Pdf Total
2024 November 3 2 5
2024 October 35 21 56
2024 September 39 40 79
2024 August 51 30 81
2024 July 32 28 60
2024 June 53 22 75
2024 May 37 29 66
2024 April 38 24 62
2024 March 44 39 83
2024 February 38 26 64
2024 January 0 1 1
2023 December 0 1 1
2023 November 0 13 13
2023 October 0 12 12
2023 September 0 2 2
2023 August 0 2 2
2023 July 0 3 3
2023 May 0 2 2
2023 March 3 7 10
2023 February 16 20 36
2023 January 25 28 53
2022 December 29 22 51
2022 November 20 22 42
2022 October 27 28 55
2022 September 26 25 51
2022 August 30 44 74
2022 July 22 31 53
2022 June 25 34 59
2022 May 29 27 56
2022 April 22 32 54
2022 March 25 30 55
2022 February 23 36 59
2022 January 34 39 73
2021 December 27 40 67
2021 November 18 41 59
2021 October 29 42 71
2021 September 21 39 60
2021 August 15 44 59
2021 July 24 35 59
2021 June 15 33 48
2021 May 16 37 53
2021 April 32 83 115
2021 March 35 31 66
2021 February 29 42 71
2021 January 15 43 58
2020 December 11 59 70
2020 November 17 19 36
2020 October 9 20 29
2020 September 18 13 31
2020 August 25 13 38
2020 July 14 16 30
2020 June 27 11 38
2020 May 21 19 40
2020 April 23 14 37
2020 March 30 15 45
2020 February 24 28 52
2020 January 40 29 69
2019 December 36 49 85
2019 November 18 10 28
2019 October 34 19 53
2019 September 36 32 68
2019 August 24 22 46
2019 July 34 37 71
2019 June 31 33 64
2019 May 31 35 66
2019 April 54 44 98
2019 March 15 30 45
2019 February 7 25 32
2019 January 10 17 27
2018 December 8 27 35
2018 November 18 52 70
2018 October 18 20 38
2018 September 12 28 40
2018 May 5 2 7
2018 April 11 13 24
2018 March 5 9 14
2018 February 10 11 21
2018 January 8 7 15
2017 December 10 55 65
2017 November 8 76 84
2017 October 14 75 89
2017 September 3 74 77
2017 August 17 76 93
2017 July 4 60 64
2017 June 13 93 106
2017 May 17 95 112
2017 April 9 118 127
2017 March 7 120 127
2017 February 6 131 137
2017 January 8 31 39
2016 December 6 42 48
2016 November 17 66 83
2016 October 19 69 88
2016 September 21 71 92
2016 August 33 35 68
2016 July 33 31 64
2016 June 37 37 74
2016 May 28 23 51
2016 April 4 0 4
2016 March 3 0 3
2016 February 7 3 10
2016 January 28 17 45
2015 December 31 28 59
2015 November 30 14 44
2015 October 6 1 7
2015 September 2 0 2
2015 June 1 0 1
Show all

Follow this link to access the full text of the article

Archivos de Bronconeumología

Are you a health professional able to prescribe or dispense drugs?