Drenaje de derrames pleurales loculados y/o tabicados mediante catéter de pequeño calibre y urocinasa (pleurofibrinólisis)
Drainage of loculated and/or multiloculate pleural effusion using a small caliber catheter and urokinase (pleural-fíbrinolysis)
Sección de Radiología Intervencionista. Hospital Universitario Lozano Blesa. Zaragoza
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"apellidos" => "Flores Cid" ] 1 => array:2 [ "nombre" => "J.M." "apellidos" => "Nogueira Coito" ] 2 => array:2 [ "nombre" => "C." "apellidos" => "Iñigo Zaera" ] ] ] ] ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289615306852?idApp=UINPBA00003Z" "url" => "/03002896/0000003200000010/v1_201506230103/S0300289615306852/v1_201506230103/es/main.assets" ] "es" => array:14 [ "idiomaDefecto" => true "titulo" => "Drenaje de derrames pleurales loculados y/o tabicados mediante catéter de pequeño calibre y urocinasa (pleurofibrinólisis)" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "510" "paginaFinal" => "515" ] ] "autores" => array:2 [ 0 => array:4 [ "autoresLista" => "M.A. de Gregorio, E.R. Alfonso, J.A. Fernández, I. Ariño" "autores" => array:4 [ 0 => array:3 [ "nombre" => "M.A." "apellidos" => "de Gregorio" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">1</span>" "identificador" => "cor0005" ] ] ] 1 => array:2 [ "nombre" => "E.R." "apellidos" => "Alfonso" ] 2 => array:2 [ "nombre" => "J.A." "apellidos" => "Fernández" ] 3 => array:2 [ "nombre" => "I." "apellidos" => "Ariño" ] ] "afiliaciones" => array:1 [ 0 => array:2 [ "entidad" => "Sección de Radiología Intervencionista. Hospital Universitario Lozano Blesa. Zaragoza" "identificador" => "aff0005" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "1" "correspondencia" => "Correspondencia: Sección de Radiología Intervencionista. Hospital Universitario Lozano Blesa. Avda. de San Juan Bosco, 15. 50009 Zaragoza." ] ] ] 1 => array:3 [ "autoresLista" => "C. Ruiz, A. Pérez-Trullén, F. Rodríguez Panadero" "autores" => array:3 [ 0 => array:3 [ "nombre" => "C." "apellidos" => "Ruiz" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "aff0010" ] ] ] 1 => array:3 [ "nombre" => "A." "apellidos" => "Pérez-Trullén" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "aff0010" ] ] ] 2 => array:3 [ "nombre" => "F." "apellidos" => "Rodríguez Panadero" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">**</span>" "identificador" => "aff0015" ] ] ] ] "afiliaciones" => array:2 [ 0 => array:3 [ "entidad" => "Servicio de Neumología. Hospital Universitario Lozano Blesa. Zaragoza" "etiqueta" => "*" "identificador" => "aff0010" ] 1 => array:3 [ "entidad" => "Servicio de Neumología. Hospital Universitario Virgen del Rocío. Sevilla" "etiqueta" => "**" "identificador" => "aff0015" ] ] ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Drainage of loculated and/or multiloculate pleural effusion using a small caliber catheter and urokinase (pleural-fíbrinolysis)" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "1996-01-02" "fechaAceptado" => "1996-05-07" "PalabrasClave" => array:2 [ "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec546176" "palabras" => array:7 [ 0 => "Urocinasa" 1 => "Fibrinólisis intrapleural" 2 => "Pleurofibrinólisis" 3 => "Derrame pleural loculado" 4 => "Drenaje percutáneo" 5 => "Ultrasonografía" 6 => "Empiema pleural" ] ] ] "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key words" "identificador" => "xpalclavsec546177" "palabras" => array:7 [ 0 => "Urokinase" 1 => "Intrapleural fibrinolysis" 2 => "Pleural fibrinolysis" 3 => "Multiloculated pleural effusion" 4 => "Percutaneous drainage" 5 => "Ultrasonography" 6 => "Pleural empyema" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "es" => array:1 [ "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Es sabido que la septación, el aumento de la viscosidad del líquido pleural y una inadecuada colocación de los tubos de drenaje torácico constituyen la principal causa de fracasos en el drenaje de las colecciones pleurales. También está recogido en la bibliografía cómo se puede solventar este tipo de problemas guiando la colocación de los tubos con medios de imagen como la ultrasonografía (US) y utilizando agentes fíbrinolíticos intrapleurales que impidan la septación y licuen la viscosidad del líquido pleural.</p><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Evaluamos nuestra experiencia, el papel y efectividad de la administración de la urocinasa (UC) intracavitaria a través de un catéter de pequeño calibre (CPC), implantado bajo control ecográfico, en el conjunto del tratamiento que requieren los derrames pleurales (DP) loculados y/o tabicados.</p><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Se drenaron 50 DP loculados y/o tabicados mediante un CPC tipo <span class="elsevierStyleItalic">pig-tail</span> de entre 8,2 y 10 F de calibre, insertado bajo control ecográfico. Los criterios para iniciar el procedimiento fueron los siguientes: DP de cualquier etiología en el que por ecografía se comprobó la presencia de tabiques o septos de fibrina y/o loculación sin que existieran contraindicaciones para el uso de UC. La dosis de UC administrada fue de 100.000 U cada 2 h hasta la resolución del derrame. Antes y después del tratamiento se midieron los niveles de dímero D con el fin de verificar la actividad fibrinolítica pleural.</p><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">En el 100% de los pacientes se ubicó el CPC en el lugar más adecuado. La cantidad media de UC administrada fue de 366.000 U y el tiempo de permanencia del CPC fue de 4,7 días. Inicialmente el drenaje fue completo en todos los DP. Evaluamos nuevamente a los pacientes a los 30 días encontrando en dos (4%) una recidiva del DP, en ocho (16%) la resolución completa sin secuelas, en 32 (64%) casi completa, quedando un pequeño engrosamiento pleural, y en ocho (16%) una resolución parcial, quedando un engrosamiento pleural mayor de 2<span class="elsevierStyleHsp" style=""></span>mm.</p><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">La utilización de CPC combinado con el uso de UC (pleurofibrinólisis) constituye un procedimiento poco invasivo, eficaz, bien tolerado por los pacientes, que acorta el tiempo de drenaje, evita secuelas posteriores y económicamente no es muy caro para el tratamiento de los DP que presentan septos de fibrina y/o están ya loculados.</p></span>" ] "en" => array:1 [ "resumen" => "<span id="abst0010" class="elsevierStyleSection elsevierViewall"><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">The main causes of pleural fluid drainage failure are known to be the formation of fibrin septa, increased viscosity in pleural fluid and inappropriate placement of chest tubes. Reports also tell us that such problems can be solved by using ultrasound as a guide for tube placement and by infusing intrapleural fibrinolitic agents to prevent the formation of septa and reduce the viscosity of pleural fluid.</p><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">To assess our experience, the role and efficacy of administering intercavitary urokinase (UK) through a small caliber catheter (SCC) implanted with ultrasound guidance as part of the treatment for pleural effusions (PE) that are multiloculated and/or loculated.</p><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">Fifty multiloculated and/or loculated PE were drained through a pig-tail type SCC between 8.2 and 10 F caliber inserted with ultrasound guidance. The criteria for prescribing the procedure were as follows: PE of any etiology with ultrasound confirmation of fibrin septa and/or multiloculation and absence of contraindication for UK administration. UK was given at a dose of 100,000 <span class="elsevierStyleSmallCaps">I</span>.U. every two hours until disappearance of PE. Before and after treatment the levels of D-dimer were measured in order to monitor pleural fibrinolitic activity.</p><p id="spar9045" class="elsevierStyleSimplePara elsevierViewall">The SCC was properly placed in all patients. UK administration was 366,000 <span class="elsevierStyleSmallCaps">I</span>.U. and time the SCC were in place was 4.7 days. All PEs were initially drained completly. We examined the patients 30 days later, finding that PE had recurred in 2 (4%), resolution was complete and without sequelae in 8 (16%), nearly complete but with slight pleural thickening in 32 (64%) and partial with pleural opacities larger than 2<span class="elsevierStyleHsp" style=""></span>mm in 8 (16%).</p><p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">Use of SCC and UK (pleural fibrinolysis) is a moderately invasive procedure that is effective and well tolerated and that shortens drainage time, prevenís sequelae and is relatively inexpensive for the treatment of PE with fibrin septation and/or multiloculation.</p></span>" ] ] "bibliografia" => array:2 [ "titulo" => "Bibliografía" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:21 [ 0 => array:3 [ "identificador" => "bib0005" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Empyema thoracis: a ten-year experience" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "C.J. Wehr" 1 => "R.B. Adkins" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "South Med J" "fecha" => "1986" "volumen" => "79" "paginaInicial" => "171" "paginaFinal" => "176" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3945848" "web" => "Medline" ] ] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib0010" "etiqueta" => "2." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Modem management of adult thoracic empyema" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "J.H. Lemmer" 1 => "M.J. Botham" 2 => "M.B. Omnger" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Thorac Cardiovasc Surg" "fecha" => "1989" "volumen" => "90" "paginaInicial" => "849" "paginaFinal" => "855" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/4068734" "web" => "Medline" ] ] ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib0015" "etiqueta" => "3." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Treatment of spontaneous bacterial empyema thoracis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "A.K. Mandal" 1 => "H. Thadepall" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Thorac Cardiovasc Surg" "fecha" => "1987" "volumen" => "94" "paginaInicial" => "414" "paginaFinal" => "418" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3626603" "web" => "Medline" ] ] ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib0020" "etiqueta" => "4." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Utilidad de la urocinasa en derrames pleurales multiloculados" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "J. Casanova" 1 => "J.M. Izquierdo" 2 => "J. Pac" 3 => "M. Mariñan" 4 => "R. Rojo" 5 => "J.C. Rumbero" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Arch Bronconeumol" "fecha" => "1995" "volumen" => "31" "paginaInicial" => "51" "paginaFinal" => "55" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7704389" "web" => "Medline" ] ] ] ] ] ] ] ] 4 => array:3 [ "identificador" => "bib0025" "etiqueta" => "5." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "CT-and ultrasound-guided catheter drainage of empyemas after chest-tube failure" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "E. Van Sonnenberg" 1 => "S.K. Nakamoto" 2 => "P.R. Mueller" 3 => "G. Casola" 4 => "C.C. Neff" 5 => "P.J. Friedman" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1148/radiology.151.2.6709904" "Revista" => array:6 [ "tituloSerie" => "Radiology" "fecha" => "1984" "volumen" => "151" "paginaInicial" => "349" "paginaFinal" => "353" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/6709904" "web" => "Medline" ] ] ] ] ] ] ] ] 5 => array:3 [ "identificador" => "bib0030" "etiqueta" => "6." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Thoracic empyema: management with image-guided catheter drainage" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "S.G. Silverman" 1 => "P.R. Mueller" 2 => "S. Saini" 3 => "P.F. Hahn" 4 => "J.F. Simeone" 5 => "B.H. Forman" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1148/radiology.169.1.3047789" "Revista" => array:6 [ "tituloSerie" => "Radiology" "fecha" => "1988" "volumen" => "169" "paginaInicial" => "5" "paginaFinal" => "9" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3047789" "web" => "Medline" ] ] ] ] ] ] ] ] 6 => array:3 [ "identificador" => "bib0035" "etiqueta" => "7." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Treatment of loculated pleural effusions with transcatheter intracavitary urokinase" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "J.S. Moulton" 1 => "P.T. Moor" 2 => "R.A. Mencini" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.2214/ajr.153.5.941" "Revista" => array:6 [ "tituloSerie" => "AJR" "fecha" => "1989" "volumen" => "153" "paginaInicial" => "941" "paginaFinal" => "945" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2801441" "web" => "Medline" ] ] ] ] ] ] ] ] 7 => array:3 [ "identificador" => "bib0040" "etiqueta" => "8." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The effect in patients of streptococcal fibrinolysin (streptokinase) and streptococcal desoxyribonuclease on fibrinous, purulent and sanguinous pleural exudations" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "W.S. Tillett" 1 => "S. Sherry" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "J Clin Invest" "fecha" => "1949" "volumen" => "23" "paginaInicial" => "173" "paginaFinal" => "179" ] ] ] ] ] ] 8 => array:3 [ "identificador" => "bib0045" "etiqueta" => "9." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The use of streptokinase-streptodornase in the treatment of hemothorax" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "S. Sherry" 1 => "W.S. Tillett" 2 => "C.T. Read" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Thorac Surg" "fecha" => "1950" "volumen" => "20" "paginaInicial" => "393" "paginaFinal" => "419" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/14774891" "web" => "Medline" ] ] ] ] ] ] ] ] 9 => array:3 [ "identificador" => "bib0050" "etiqueta" => "10." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Intrapleural streptokinase in the treatment of hemothorax and empyema" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "N.P. Bergh" 1 => "R. Ekroth" 2 => "S. Larsson" 3 => "P. Nagy" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Scand J Thorac Cardiovasc Surg" "fecha" => "1977" "volumen" => "11" "paginaInicial" => "265" "paginaFinal" => "268" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/594722" "web" => "Medline" ] ] ] ] ] ] ] ] 10 => array:3 [ "identificador" => "bib0055" "etiqueta" => "11." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Intrapleurally administered streptokinase in the treatment of acute loculated nonpurulent parapneumonic effusions" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "C. Henke" 1 => "J. Leahterman" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1164/ajrccm/145.3.680" "Revista" => array:6 [ "tituloSerie" => "Am Rev Respir Dis" "fecha" => "1992" "volumen" => "145" "paginaInicial" => "680" "paginaFinal" => "684" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1546851" "web" => "Medline" ] ] ] ] ] ] ] ] 11 => array:3 [ "identificador" => "bib0060" "etiqueta" => "12." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Uso de la estreptoquinasa intrapleural en el tratamiento de empiemas y derrames pleurales paraneumónicos complicados" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "I. Alfageme" 1 => "L. Moreno" 2 => "E. Muñoz" 3 => "S. Umbría" 4 => "N. Peña" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Arch Bronconeumol" "fecha" => "1993" "volumen" => "29" "paginaInicial" => "12" "paginaFinal" => "15" ] ] ] ] ] ] 12 => array:3 [ "identificador" => "bib0065" "etiqueta" => "13." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Décaillotage pleural par l’urokinase" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "R. Dubois" 1 => "C. Drieu" 2 => "C. Dubois" 3 => "F. Toulemonde" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Extralt des Annales de l’anesthesiologie francaise" "fecha" => "1973" "volumen" => "14" "paginaInicial" => "293" "paginaFinal" => "296" ] ] ] ] ] ] 13 => array:3 [ "identificador" => "bib0070" "etiqueta" => "14." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Transcatheter intracavitary fibrinolysis of infected extravascular hematomas" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "R.L. Vogelzang" 1 => "R.S. Tobin" 2 => "S. Burstein" 3 => "S.L. Amscheutz" 4 => "M. Marzano" 5 => "J.M. Kozlowski" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.2214/ajr.148.2.378" "Revista" => array:6 [ "tituloSerie" => "AJR" "fecha" => "1987" "volumen" => "148" "paginaInicial" => "378" "paginaFinal" => "380" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3492117" "web" => "Medline" ] ] ] ] ] ] ] ] 14 => array:3 [ "identificador" => "bib0075" "etiqueta" => "15." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Treatment of thoracic multiloculated empyemas with intracavitary urokinase: a prospective study" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "K.S. Lee" 1 => "J.-G. Im" 2 => "S.H. Hwang" 3 => "W.K. Bae" 4 => "B.H. Lee" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1148/radiology.179.3.2027990" "Revista" => array:6 [ "tituloSerie" => "Radiology" "fecha" => "1991" "volumen" => "179" "paginaInicial" => "771" "paginaFinal" => "775" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2027990" "web" => "Medline" ] ] ] ] ] ] ] ] 15 => array:3 [ "identificador" => "bib0080" "etiqueta" => "16." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Tratamiento de los derrames pleurales loculados con uroquinasa intrapleural transcatéter" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "M.A. De Gregorio" 1 => "E.R. Alfonso" 2 => "J.A. Fernández" 3 => "J.L. Villavieja" 4 => "I. Ariño" 5 => "F. Duce" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Estudio preliminar. Arch Bronconeumol" "fecha" => "1993" "volumen" => "29" "paginaInicial" => "229" "paginaFinal" => "231" ] ] ] ] ] ] 16 => array:3 [ "identificador" => "bib0085" "etiqueta" => "17." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Sonographic guidance in diagnostic and therapeutic interventions in the pleural space" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "P.V. O’Moore" 1 => "P.R. Mueller" 2 => "J.F. Simeone" 3 => "S. Saini" 4 => "R.J. Butch" 5 => "P. Hahn" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.2214/ajr.149.1.1" "Revista" => array:6 [ "tituloSerie" => "AJR" "fecha" => "1987" "volumen" => "149" "paginaInicial" => "1" "paginaFinal" => "5" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3296705" "web" => "Medline" ] ] ] ] ] ] ] ] 17 => array:3 [ "identificador" => "bib0090" "etiqueta" => "18." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Imaging of the pleura" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "N.L. Müller" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1148/radiology.186.2.8421723" "Revista" => array:6 [ "tituloSerie" => "Radiology" "fecha" => "1993" "volumen" => "186" "paginaInicial" => "297" "paginaFinal" => "309" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8421723" "web" => "Medline" ] ] ] ] ] ] ] ] 18 => array:3 [ "identificador" => "bib0095" "etiqueta" => "19." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Realtime sonography of the pleural opacities" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "J.H. Hirsch" 1 => "J.V. Rogers" 2 => "L.A. Mack" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.2214/ajr.136.2.297" "Revista" => array:6 [ "tituloSerie" => "AJR" "fecha" => "1981" "volumen" => "136" "paginaInicial" => "297" "paginaFinal" => "301" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/6781250" "web" => "Medline" ] ] ] ] ] ] ] ] 19 => array:3 [ "identificador" => "bib0100" "etiqueta" => "20." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Quatification of pleural effusions: sonography versus radiography" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "K.L. Eibenberger" 1 => "W.L. Dock" 2 => "M.E. Ammann" 3 => "R. Dorffner" 4 => "M. Hörmann" 5 => "F. Grabenwöger" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1148/radiology.191.3.8184046" "Revista" => array:6 [ "tituloSerie" => "Radiology" "fecha" => "1994" "volumen" => "191" "paginaInicial" => "681" "paginaFinal" => "684" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8184046" "web" => "Medline" ] ] ] ] ] ] ] ] 20 => array:3 [ "identificador" => "bib0105" "etiqueta" => "21." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Value of sonography in determining the nature of pleural effusion: analysis of 320 cases" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "P.C. Yang" 1 => "K.T. Luh" 2 => "D.B. Chang" 3 => "H.D. Wu" 4 => "C.J. Yu" 5 => "S.H. Kuo" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.2214/ajr.159.1.1609716" "Revista" => array:6 [ "tituloSerie" => "AJR" "fecha" => "1992" "volumen" => "159" "paginaInicial" => "29" "paginaFinal" => "33" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1609716" "web" => "Medline" ] ] ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "es" "url" => "/03002896/0000003200000010/v1_201506230103/S0300289615306864/v1_201506230103/es/main.assets" "Apartado" => array:4 [ "identificador" => "9277" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Originales" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/03002896/0000003200000010/v1_201506230103/S0300289615306864/v1_201506230103/es/main.pdf?idApp=UINPBA00003Z&text.app=https://archbronconeumol.org/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289615306864?idApp=UINPBA00003Z" ]
| Year/Month | Html | Total | |
|---|---|---|---|
| 2024 November | 66 | 6 | 72 |
| 2024 October | 600 | 34 | 634 |
| 2024 September | 439 | 56 | 495 |
| 2024 August | 420 | 50 | 470 |
| 2024 July | 201 | 38 | 239 |
| 2024 June | 269 | 32 | 301 |
| 2024 May | 227 | 50 | 277 |
| 2024 April | 193 | 80 | 273 |
| 2024 March | 201 | 96 | 297 |
| 2024 February | 136 | 74 | 210 |
| 2024 January | 1 | 28 | 29 |
| 2023 December | 0 | 11 | 11 |
| 2023 November | 0 | 8 | 8 |
| 2023 October | 0 | 5 | 5 |
| 2023 September | 0 | 5 | 5 |
| 2023 August | 0 | 3 | 3 |
| 2023 July | 0 | 8 | 8 |
| 2023 June | 0 | 4 | 4 |
| 2023 April | 0 | 5 | 5 |
| 2023 March | 3 | 15 | 18 |
| 2023 February | 28 | 39 | 67 |
| 2023 January | 27 | 47 | 74 |
| 2022 December | 42 | 34 | 76 |
| 2022 November | 40 | 35 | 75 |
| 2022 October | 28 | 60 | 88 |
| 2022 September | 25 | 34 | 59 |
| 2022 August | 32 | 61 | 93 |
| 2022 July | 21 | 60 | 81 |
| 2022 June | 25 | 38 | 63 |
| 2022 May | 29 | 46 | 75 |
| 2022 April | 30 | 64 | 94 |
| 2022 March | 28 | 89 | 117 |
| 2022 February | 27 | 80 | 107 |
| 2022 January | 23 | 124 | 147 |
| 2021 December | 17 | 89 | 106 |
| 2021 November | 15 | 73 | 88 |
| 2021 October | 22 | 79 | 101 |
| 2021 September | 12 | 83 | 95 |
| 2021 August | 9 | 69 | 78 |
| 2021 July | 11 | 56 | 67 |
| 2021 June | 16 | 50 | 66 |
| 2021 May | 18 | 58 | 76 |
| 2021 April | 101 | 59 | 160 |
| 2021 March | 31 | 62 | 93 |
| 2021 February | 28 | 31 | 59 |
| 2021 January | 22 | 46 | 68 |
| 2020 December | 25 | 41 | 66 |
| 2020 November | 12 | 76 | 88 |
| 2020 October | 10 | 76 | 86 |
| 2020 September | 19 | 45 | 64 |
| 2020 August | 13 | 80 | 93 |
| 2020 July | 17 | 59 | 76 |
| 2020 June | 18 | 95 | 113 |
| 2020 May | 16 | 110 | 126 |
| 2020 April | 25 | 77 | 102 |
| 2020 March | 32 | 112 | 144 |
| 2020 February | 27 | 164 | 191 |
| 2020 January | 48 | 184 | 232 |
| 2019 December | 33 | 129 | 162 |
| 2019 November | 23 | 116 | 139 |
| 2019 October | 18 | 224 | 242 |
| 2019 September | 20 | 218 | 238 |
| 2019 August | 18 | 224 | 242 |
| 2019 July | 19 | 241 | 260 |
| 2019 June | 20 | 220 | 240 |
| 2019 May | 27 | 298 | 325 |
| 2019 April | 20 | 358 | 378 |
| 2019 March | 12 | 249 | 261 |
| 2019 February | 8 | 227 | 235 |
| 2019 January | 10 | 185 | 195 |
| 2018 December | 16 | 202 | 218 |
| 2018 November | 27 | 277 | 304 |
| 2018 October | 37 | 204 | 241 |
| 2018 September | 16 | 201 | 217 |
| 2018 May | 8 | 2 | 10 |
| 2018 April | 7 | 7 | 14 |
| 2018 March | 7 | 10 | 17 |
| 2018 February | 8 | 13 | 21 |
| 2018 January | 12 | 27 | 39 |
| 2017 December | 7 | 46 | 53 |
| 2017 November | 9 | 114 | 123 |
| 2017 October | 9 | 134 | 143 |
| 2017 September | 9 | 102 | 111 |
| 2017 August | 21 | 129 | 150 |
| 2017 July | 2 | 86 | 88 |
| 2017 June | 13 | 95 | 108 |
| 2017 May | 12 | 73 | 85 |
| 2017 April | 6 | 65 | 71 |
| 2017 March | 19 | 64 | 83 |
| 2017 February | 6 | 53 | 59 |
| 2017 January | 4 | 24 | 28 |
| 2016 December | 9 | 21 | 30 |
| 2016 November | 22 | 30 | 52 |
| 2016 October | 29 | 46 | 75 |
| 2016 September | 36 | 49 | 85 |
| 2016 August | 43 | 18 | 61 |
| 2016 July | 37 | 12 | 49 |
| 2016 June | 44 | 25 | 69 |
| 2016 May | 49 | 25 | 74 |
| 2016 April | 22 | 0 | 22 |
| 2016 March | 13 | 3 | 16 |
| 2016 February | 15 | 3 | 18 |
| 2016 January | 39 | 27 | 66 |
| 2015 December | 19 | 15 | 34 |
| 2015 November | 37 | 5 | 42 |
| 2015 October | 6 | 1 | 7 |
| 2015 September | 2 | 0 | 2 |
| 2015 June | 1 | 0 | 1 |
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