Los agonistas adrenérgicos β2 y su influencia en el rendimiento físico
β2 adrenergic agonists and their influence on physical performance
F. Drobnic*
Departamento de Fisiología y Valoración Funcional. Centre d’Alt Rendiment. Sant Cugat del Vallés. Barcelona
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Villate, J. Barrón, R. Zalacaín, M.I. Urcelay, J.M. Hernández, M. Argumedo" "autores" => array:6 [ 0 => array:2 [ "nombre" => "J.I." "apellidos" => "Villate" ] 1 => array:2 [ "nombre" => "J." "apellidos" => "Barrón" ] 2 => array:2 [ "nombre" => "R." "apellidos" => "Zalacaín" ] 3 => array:2 [ "nombre" => "M.I." "apellidos" => "Urcelay" ] 4 => array:2 [ "nombre" => "J.M." "apellidos" => "Hernández" ] 5 => array:2 [ "nombre" => "M." "apellidos" => "Argumedo" ] ] ] ] ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289615306426?idApp=UINPBA00003Z" "url" => "/03002896/0000003300000003/v1_201506200427/S0300289615306426/v1_201506200427/es/main.assets" ] "es" => array:14 [ "idiomaDefecto" => true "titulo" => "Los agonistas adrenérgicos β<span class="elsevierStyleInf">2</span> y su influencia en el rendimiento físico" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "136" "paginaFinal" => "142" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "F. Drobnic" "autores" => array:1 [ 0 => array:3 [ "nombre" => "F." "apellidos" => "Drobnic" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor0005" ] ] ] ] "afiliaciones" => array:1 [ 0 => array:2 [ "entidad" => "Departamento de Fisiología y Valoración Funcional. Centre d’Alt Rendiment. Sant Cugat del Vallés. Barcelona" "identificador" => "aff0005" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "*" "correspondencia" => "Correspondencia: Departamento de Fisiología y Valoración Funcional. Centre d’Alt Rendiment. Aptdo. de Correos 129. 08190 Sant Cugat del Vallés. Barcelona." ] ] ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "β<span class="elsevierStyleInf">2</span> adrenergic agonists and their influence on physical performance" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "1996-05-28" "fechaAceptado" => "1996-09-03" "PalabrasClave" => array:2 [ "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec545608" "palabras" => array:3 [ 0 => "Beta-2-adrenérgicos" 1 => "asma de esfuerzo" 2 => "dopaje" ] ] ] "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key words" "identificador" => "xpalclavsec545609" "palabras" => array:3 [ 0 => "Betha-2-adrenergics" 1 => "Exercise-related asthma" 2 => "Doping" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "es" => array:1 [ "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Cada día es más evidente que un individuo con asma no sólo puede beneficiarse por la práctica de una actividad física, sino también puede llegar a unos niveles de rendimiento deportivo como los no asmáticos. Para ello, además de utilizar unas medidas terapéuticas adecuadas, precisa la utilización de ciertos fármacos para prevenir la crisis de asma de esfuerzo. Los agonistas β<span class="elsevierStyleInf">2</span> son fármacos con un cierto potencial “anabólico” proteico, dependiente de la dosis y permanencia en los tejidos, tanto en animales de laboratorio, como de granja o en humanos. Debe considerarse que la dosis administrada para obtener este efecto es muy superior a la utilizada como terapéutica para el asma o las enfermedades respiratorias. Si se tiene en cuenta que los tratamientos orales son bastante menos efectivos en el asma de esfuerzo que los inhalados, que las dosis son inferiores y que los efectos ergogénicos de las sustancias estudiadas son nulos o no valorables, parece lógico permitir que el individuo con asma los utilice para realizar una actividad física. Por otra parte, el asmático cuya asma es tan severa que precisa el uso de agonistas β<span class="elsevierStyleInf">2</span> por vía oral, cabe considerar que estará lo bastante enfermo como para no poder participar en una actividad deportiva mientras dure su estado.</p></span>" ] "en" => array:1 [ "resumen" => "<span id="abst0010" class="elsevierStyleSection elsevierViewall"><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">That asthmatics benefit not only from physical exercise but that they can even reach performance levels comparable to that of non asthmatics is becoming increasingly clear. To reach such a level, asthmatics need to use drugs to prevent effort-related asthma attacks in addition to taking appropriate therapeutic measures. β<span class="elsevierStyleInf">2</span> agonists are drugs that potentially produce a certain amount of “anabolic” effect, depending on the dose and permanence in tissues, in laboratory and farm animals as well as in humans. We must conclude that the dose needed to obtain this effect is higher than that used for therapeutic purposes in asthma or respiratory diseases. Bearing in mind that oral treatments are considerably less effective than inhaled drugs in exercise-related asthma attacks, that the doses of the latter are lower and that the ergogenic effects of the substances studied are nil or below detection levels, it seems logical to allow individuals with asthma who use such substances to engage in physical exercise. Moreover, the asthmatic whose disease is so severe as to require the use of orally administered β<span class="elsevierStyleInf">2</span> agonists will in all likelihood be too ill to participate in a sport while that status persists.</p></span>" ] ] "bibliografia" => array:2 [ "titulo" => "Bibliografía" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:56 [ 0 => array:3 [ "identificador" => "bib0005" "etiqueta" => "1." 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| Year/Month | Html | Total | |
|---|---|---|---|
| 2024 November | 12 | 5 | 17 |
| 2024 October | 116 | 22 | 138 |
| 2024 September | 74 | 39 | 113 |
| 2024 August | 122 | 39 | 161 |
| 2024 July | 92 | 29 | 121 |
| 2024 June | 105 | 30 | 135 |
| 2024 May | 96 | 52 | 148 |
| 2024 April | 90 | 60 | 150 |
| 2024 March | 78 | 86 | 164 |
| 2024 February | 80 | 106 | 186 |
| 2024 January | 0 | 51 | 51 |
| 2023 December | 0 | 45 | 45 |
| 2023 November | 0 | 58 | 58 |
| 2023 October | 3 | 111 | 114 |
| 2023 September | 4 | 50 | 54 |
| 2023 August | 7 | 26 | 33 |
| 2023 July | 2 | 12 | 14 |
| 2023 June | 0 | 1 | 1 |
| 2023 May | 0 | 3 | 3 |
| 2023 April | 0 | 3 | 3 |
| 2023 March | 3 | 8 | 11 |
| 2023 February | 31 | 43 | 74 |
| 2023 January | 40 | 42 | 82 |
| 2022 December | 35 | 30 | 65 |
| 2022 November | 39 | 39 | 78 |
| 2022 October | 65 | 51 | 116 |
| 2022 September | 49 | 36 | 85 |
| 2022 August | 56 | 56 | 112 |
| 2022 July | 36 | 56 | 92 |
| 2022 June | 33 | 54 | 87 |
| 2022 May | 48 | 61 | 109 |
| 2022 April | 67 | 67 | 134 |
| 2022 March | 46 | 57 | 103 |
| 2022 February | 36 | 65 | 101 |
| 2022 January | 59 | 68 | 127 |
| 2021 December | 64 | 58 | 122 |
| 2021 November | 77 | 104 | 181 |
| 2021 October | 125 | 91 | 216 |
| 2021 September | 62 | 58 | 120 |
| 2021 August | 72 | 38 | 110 |
| 2021 July | 51 | 55 | 106 |
| 2021 June | 48 | 59 | 107 |
| 2021 May | 51 | 56 | 107 |
| 2021 April | 70 | 153 | 223 |
| 2021 March | 62 | 62 | 124 |
| 2021 February | 82 | 48 | 130 |
| 2021 January | 58 | 35 | 93 |
| 2020 December | 62 | 23 | 85 |
| 2020 November | 53 | 53 | 106 |
| 2020 October | 71 | 61 | 132 |
| 2020 September | 38 | 16 | 54 |
| 2020 August | 66 | 40 | 106 |
| 2020 July | 57 | 41 | 98 |
| 2020 June | 31 | 26 | 57 |
| 2020 May | 36 | 35 | 71 |
| 2020 April | 45 | 56 | 101 |
| 2020 March | 41 | 36 | 77 |
| 2020 February | 49 | 60 | 109 |
| 2020 January | 59 | 50 | 109 |
| 2019 December | 54 | 54 | 108 |
| 2019 November | 37 | 32 | 69 |
| 2019 October | 33 | 31 | 64 |
| 2019 September | 19 | 54 | 73 |
| 2019 August | 18 | 16 | 34 |
| 2019 July | 19 | 47 | 66 |
| 2019 June | 24 | 42 | 66 |
| 2019 May | 21 | 60 | 81 |
| 2019 April | 12 | 53 | 65 |
| 2019 March | 29 | 39 | 68 |
| 2019 February | 11 | 18 | 29 |
| 2019 January | 15 | 15 | 30 |
| 2018 December | 13 | 21 | 34 |
| 2018 November | 28 | 45 | 73 |
| 2018 October | 29 | 26 | 55 |
| 2018 September | 18 | 13 | 31 |
| 2018 May | 8 | 1 | 9 |
| 2018 April | 6 | 4 | 10 |
| 2018 March | 6 | 6 | 12 |
| 2018 February | 8 | 7 | 15 |
| 2018 January | 4 | 6 | 10 |
| 2017 December | 10 | 12 | 22 |
| 2017 November | 8 | 19 | 27 |
| 2017 October | 11 | 17 | 28 |
| 2017 September | 7 | 15 | 22 |
| 2017 August | 11 | 15 | 26 |
| 2017 July | 4 | 16 | 20 |
| 2017 June | 13 | 26 | 39 |
| 2017 May | 10 | 12 | 22 |
| 2017 April | 10 | 10 | 20 |
| 2017 March | 7 | 15 | 22 |
| 2017 February | 5 | 9 | 14 |
| 2017 January | 4 | 4 | 8 |
| 2016 December | 15 | 12 | 27 |
| 2016 November | 34 | 27 | 61 |
| 2016 October | 25 | 29 | 54 |
| 2016 September | 33 | 17 | 50 |
| 2016 August | 25 | 6 | 31 |
| 2016 July | 39 | 9 | 48 |
| 2016 June | 29 | 13 | 42 |
| 2016 May | 10 | 1 | 11 |
| 2016 April | 12 | 0 | 12 |
| 2016 March | 13 | 0 | 13 |
| 2016 February | 19 | 0 | 19 |
| 2016 January | 14 | 6 | 20 |
| 2015 December | 23 | 11 | 34 |
| 2015 November | 31 | 7 | 38 |
| 2015 October | 6 | 1 | 7 |
| 2015 September | 1 | 0 | 1 |
| 2015 June | 1 | 0 | 1 |
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