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Neumotórax secundario inducido por quimioterapia
Chemotherapy-Induced Secondary Pneumothorax
Fernando Bazan
, Ivan Vollmer, Angel Gayete
Corresponding author
Servicio de Radiodiagnóstico, Hospital del Mar, Parc de Salut Mar, Barcelona, España
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Dos días antes había recibido su tercera sesión de quimioterapia (temozolamida y bevacizumab).</p><p id="par0010" class="elsevierStylePara elsevierViewall">Se le realizó una radiografía (<a class="elsevierStyleCrossRef" href="#fig0005">fig. 1</a>A) y TC de tórax (<a class="elsevierStyleCrossRef" href="#fig0005">fig. 1</a>B,C), que mostraron: sarcoma a nivel húmero-axilar derecho, múltiples metástasis pulmonares, algunas de ellas cavitadas, y un leve neumotórax bilateral. Dados los hallazgos radiológicos y la correlación clínica, se realizó el diagnóstico de neumotórax secundario a cavitación de metástasis inducidas por la quimioterapia, ya que en el estudio previo no estaban cavitadas.</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><p id="par0015" class="elsevierStylePara elsevierViewall">El neumotórax bilateral se trató de manera conservadora, y 10<span class="elsevierStyleHsp" style=""></span>días después se resolvió totalmente. Lamentablemente, el paciente falleció varias semanas después debido a complicaciones de las metástasis pulmonares.</p><p id="par0020" class="elsevierStylePara elsevierViewall">Las neoplasias pulmonares primarias y metastásicas pueden cavitarse de manera natural o después de quimioterapia; si una lesión cavitada está ubicada periféricamente, puede abrirse al espacio pleural y producir un neumotórax espontáneo<a class="elsevierStyleCrossRefs" href="#bib0005"><span class="elsevierStyleSup">1,2</span></a>. Las neoplasias más frecuentes con esta característica son los sarcomas periféricos: osteosarcoma, sarcoma sinovial y angiosarcoma<a class="elsevierStyleCrossRefs" href="#bib0005"><span class="elsevierStyleSup">1,2</span></a>.</p></span>" "pdfFichero" => "main.pdf" "tienePdf" => true "multimedia" => array:1 [ 0 => array:7 [ "identificador" => "fig0005" "etiqueta" => "Figura 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 808 "Ancho" => 2400 "Tamanyo" => 297290 ] ] "descripcion" => array:1 [ "es" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Radiografía (A) y tomografía computarizada (B,C) de tórax en las que se visualizan el sarcoma a nivel húmero-axilar derecho (estrella naranja), masa en pulmón izquierdo (flecha blanca), varios nódulos sólidos (flechas naranjas) y cavitados (flechas azules), así como leve neumotórax bilateral (estrellas azules).</p>" ] ] ] "bibliografia" => array:2 [ "titulo" => "Bibliografía" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:2 [ 0 => array:3 [ "identificador" => "bib0005" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Spontaneous pneumothorax after chemotherapy for sarcoma with lung metastases: Case report and consideration of pathogenesis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "A. Fiorelli" 1 => "G. Vicidomini" 2 => "F. Napolitano" 3 => "M. Santini" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.3978/j.issn.2072-1439.2010.12.01" "Revista" => array:6 [ "tituloSerie" => "J Thorac Dis" "fecha" => "2011" "volumen" => "3" "paginaInicial" => "138" "paginaFinal" => "140" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/22263077" "web" => "Medline" ] ] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib0010" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "A comprehensive review of spontaneous pneumothorax complicating sarcoma" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "J.B. Hoag" 1 => "M. Sherman" 2 => "Q. Fasihuddin" 3 => "M.E. Lund" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1378/chest.09-2292" "Revista" => array:6 [ "tituloSerie" => "Chest" "fecha" => "2010" "volumen" => "138" "paginaInicial" => "510" "paginaFinal" => "518" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/20382720" "web" => "Medline" ] ] ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "es" "url" => "/03002896/0000005000000001/v1_201401160024/S0300289613002652/v1_201401160024/es/main.assets" "Apartado" => array:4 [ "identificador" => "21422" "tipo" => "SECCION" "es" => array:2 [ "titulo" => "Clinical Images / Imágenes clínicas" "idiomaDefecto" => true ] "idiomaDefecto" => "es" ] "PDF" => "https://static.elsevier.es/multimedia/03002896/0000005000000001/v1_201401160024/S0300289613002652/v1_201401160024/es/main.pdf?idApp=UINPBA00003Z&text.app=https://archbronconeumol.org/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289613002652?idApp=UINPBA00003Z" ]
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