Correspondencia: Service de Pneumologie et Réanimation Respiratoire. Centre Hospitalier et Universitaire de Dijon. 2 Bd Marechal de Lattre de Tassigny. 21034 Dijon. France
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"apellidos" => "Cañada" ] ] ] ] ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289603753800?idApp=UINPBA00003Z" "url" => "/03002896/0000003900000006/v1_201307081444/S0300289603753800/v1_201307081444/es/main.assets" ] "es" => array:14 [ "idiomaDefecto" => true "titulo" => "Hemorragia alveolar asociada a enfermedad inflamatoria intestinal y tiroiditis de Hashimoto" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "283" "paginaFinal" => "285" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "C. Rabec, J. Barcat, D. Rey" "autores" => array:3 [ 0 => array:4 [ "nombre" => "C." "apellidos" => "Rabec" "email" => array:1 [ 0 => "claudio.rabec@chu-dijon.fr" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">¿</span>" "identificador" => "cor0005" ] ] ] 1 => array:3 [ "nombre" => "J." "apellidos" => "Barcat" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] ] 2 => array:3 [ "nombre" => "D." "apellidos" => "Rey" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] ] ] ] "afiliaciones" => array:2 [ 0 => array:3 [ "entidad" => "División de Neumología (Dra. M.C. de Salvo). Centro de Insuficiencia Respiratoria y Patología Respiratoria del Sueño. Hospital Tornu. Buenos Aires. Argentina" "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "Sección de Anatomía Patológica. Centro de Insuficiencia Respiratoria y Patología Respiratoria del Sueño. Hospital Tornu. Buenos Aires. Argentina" "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Correspondencia: Service de Pneumologie et Réanimation Respiratoire. Centre Hospitalier et Universitaire de Dijon. 2 Bd Marechal de Lattre de Tassigny. 21034 Dijon. France" ] ] ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Alveolar hemorrhage associated with intestinal inflammatory disease and Hashimoto thyroiditis" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2002-10-17" "fechaAceptado" => "2003-01-07" "PalabrasClave" => array:2 [ "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec190293" "palabras" => array:3 [ 0 => "Hemorragia alveolar" 1 => "Enfermedad inflamatoria intestinal" 2 => "Tiroiditis autoinmune" ] ] ] "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key words" "identificador" => "xpalclavsec190294" "palabras" => array:3 [ 0 => "Alveolar hemorrhage" 1 => "Inflammatory bowel disease" 2 => "Autoimmune thyroiditis" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "es" => array:1 [ "resumen" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">La hemorragia alveolar difusa (HAD) se caracteriza por la presencia de hemorragia difusa dentro de los espacios alveolares. Histopatológicamente puede clasificarse en tres grupos: por agresión inmunológica de membrana (”capilaritis“), por daño alveolar difuso (en el marco de un síndrome de distrés respiratorio agudo) o sin lesión alveolar o capilar. En los 2 primeros grupos, el compromiso pulmonar ocurre habitualmente en el marco de una enfermedad sistémica. En el último, el compromiso es por lo general exclusivamente pulmonar y se define como hemosiderosis pulmonar</p><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Se presenta un caso de hemorragia pulmonar no vinculada a capilaritis ni a daño alveolar, asociado a enfermedad inflamatoria intestinal y tiroiditis de Hashimoto. El caso presenta un doble interés dado que, por un lado, esta asociación de entidades no está descrita en la bibliografía y, por otro, la presencia de hemorragia alveolar sin daño tisular evidente, en un contexto de enfermedades reconocidas como autoinmunes, puede ampliar el espectro a un nuevo mecanismo fisiopatológico de hemorragia alveolar</p>" ] "en" => array:1 [ "resumen" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Diffuse alveolar hemorrhage (DAH) is characterized by diffuse bleeding into alveolar spaces. Three histopathological patterns may be seen: 1) pulmonary capillaritis due to immunological aggression to the membrane, 2) diffuse alveolar damage within the context of acute respiratory distress syndrome, and 3) and ”bland“ DAH without alveolar or capillary damage. In the first two groups, pulmonary damage usually occurs within the context of a systemic disease. In the last, injury is usually found only in the lung, an entity called pulmonary hemosiderosis</p><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">We present a case of DAH with neither capillaritis nor diffuse alveolar damage in association with inflammatory bowel disease and Hashimoto thyroiditis. The case is interesting both because the association has not yet been described in the literature and because the presence of alveolar bleeding without evident tissue damage within the context of known autoimmune diseases may extend the field to include a new pathophysiological mechanism of pulmonary hemorrhage</p>" ] ] "bibliografia" => array:2 [ "titulo" => "Bibliografía" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:15 [ 0 => array:3 [ "identificador" => "bib0005" "etiqueta" => "1." 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2021 February | 49 | 12 | 61 |
2021 January | 39 | 22 | 61 |
2020 December | 27 | 12 | 39 |
2020 November | 25 | 8 | 33 |
2020 October | 17 | 6 | 23 |
2020 September | 25 | 5 | 30 |
2020 August | 35 | 7 | 42 |
2020 July | 16 | 20 | 36 |
2020 June | 26 | 9 | 35 |
2020 May | 23 | 13 | 36 |
2020 April | 21 | 12 | 33 |
2020 March | 20 | 21 | 41 |
2020 February | 19 | 21 | 40 |
2020 January | 33 | 28 | 61 |
2019 December | 32 | 29 | 61 |
2019 November | 18 | 6 | 24 |
2019 October | 11 | 19 | 30 |
2019 September | 20 | 16 | 36 |
2019 August | 23 | 16 | 39 |
2019 July | 20 | 20 | 40 |
2019 June | 24 | 12 | 36 |
2019 May | 26 | 45 | 71 |
2019 April | 57 | 46 | 103 |
2019 March | 17 | 22 | 39 |
2019 February | 5 | 8 | 13 |
2019 January | 2 | 10 | 12 |
2018 December | 11 | 17 | 28 |
2018 November | 15 | 14 | 29 |
2018 October | 22 | 16 | 38 |
2018 September | 14 | 13 | 27 |
2018 May | 3 | 1 | 4 |
2018 April | 14 | 7 | 21 |
2018 March | 4 | 7 | 11 |
2018 February | 8 | 7 | 15 |
2018 January | 6 | 10 | 16 |
2017 December | 6 | 16 | 22 |
2017 November | 5 | 11 | 16 |
2017 October | 7 | 12 | 19 |
2017 September | 4 | 4 | 8 |
2017 August | 10 | 16 | 26 |
2017 July | 7 | 12 | 19 |
2017 June | 13 | 23 | 36 |
2017 May | 13 | 16 | 29 |
2017 April | 3 | 8 | 11 |
2017 March | 4 | 9 | 13 |
2017 February | 3 | 9 | 12 |
2017 January | 3 | 7 | 10 |
2016 December | 8 | 7 | 15 |
2016 November | 25 | 22 | 47 |
2016 October | 16 | 22 | 38 |
2016 September | 20 | 18 | 38 |
2016 August | 20 | 10 | 30 |
2016 July | 29 | 16 | 45 |
2016 June | 30 | 16 | 46 |
2016 May | 13 | 4 | 17 |
2016 April | 5 | 3 | 8 |
2016 March | 10 | 2 | 12 |
2016 February | 10 | 3 | 13 |
2016 January | 20 | 17 | 37 |
2015 December | 26 | 15 | 41 |
2015 November | 24 | 6 | 30 |
2015 October | 77 | 1 | 78 |
2015 September | 61 | 0 | 61 |
2015 August | 66 | 0 | 66 |
2015 July | 68 | 0 | 68 |
2015 June | 66 | 0 | 66 |
2015 May | 104 | 0 | 104 |
2015 April | 54 | 0 | 54 |
2015 March | 74 | 0 | 74 |
2015 February | 51 | 0 | 51 |
2015 January | 60 | 0 | 60 |
2014 December | 58 | 0 | 58 |
2014 November | 72 | 0 | 72 |
2014 October | 88 | 0 | 88 |
2014 September | 46 | 0 | 46 |
2014 August | 63 | 0 | 63 |
2014 July | 62 | 0 | 62 |
2014 June | 67 | 0 | 67 |
2014 May | 106 | 0 | 106 |
2014 April | 77 | 0 | 77 |
2014 March | 84 | 0 | 84 |
2014 February | 77 | 0 | 77 |
2014 January | 66 | 0 | 66 |
2013 December | 74 | 0 | 74 |
2013 November | 87 | 0 | 87 |
2013 October | 86 | 0 | 86 |
2013 September | 94 | 0 | 94 |
2013 August | 80 | 0 | 80 |
2013 July | 80 | 0 | 80 |
2013 June | 73 | 0 | 73 |
2013 May | 83 | 0 | 83 |
2013 April | 69 | 0 | 69 |
2013 March | 21 | 0 | 21 |
2000 January | 5722 | 0 | 5722 |