Lobectomía frente a resección limitada en el tratamiento del cáncer pulmonar no microcítico en estadio I. Estudio de 78 casos
Lobectomy versus limited resection to treat non-small cell lung cancer in stage I: a study of 78 cases
J.J. Fibla Alfara
, G. Gómez Sebastián, C. Farina Ríos, A. Carvajal Carrasco, G. Estrada Saló, C. León González
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juanjofibla@hotmail.com
Correspondencia: Servicio de Cirugía Torácica. Hospital de la Santa Creu i Sant Pau. Sant Antoni M. Claret, 167. 08025 Barcelona. España
Correspondencia: Servicio de Cirugía Torácica. Hospital de la Santa Creu i Sant Pau. Sant Antoni M. Claret, 167. 08025 Barcelona. España
Servicio de Cirugía Torácica. Hospital de la Santa Creu i Sant Pau. Barcelona. España
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Estudio de 78 casos" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "217" "paginaFinal" => "220" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "J.J. Fibla Alfara, G. Gómez Sebastián, C. Farina Ríos, A. Carvajal Carrasco, G. Estrada Saló, C. León González" "autores" => array:6 [ 0 => array:4 [ "nombre" => "J.J." "apellidos" => "Fibla Alfara" "email" => array:1 [ 0 => "juanjofibla@hotmail.com" ] "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">¿</span>" "identificador" => "cor0005" ] ] ] 1 => array:2 [ "nombre" => "G." "apellidos" => "Gómez Sebastián" ] 2 => array:2 [ "nombre" => "C." "apellidos" => "Farina Ríos" ] 3 => array:2 [ "nombre" => "A." "apellidos" => "Carvajal Carrasco" ] 4 => array:2 [ "nombre" => "G." "apellidos" => "Estrada Saló" ] 5 => array:2 [ "nombre" => "C." "apellidos" => "León González" ] ] "afiliaciones" => array:1 [ 0 => array:1 [ "entidad" => "Servicio de Cirugía Torácica. Hospital de la Santa Creu i Sant Pau. Barcelona. España" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Correspondencia: Servicio de Cirugía Torácica. Hospital de la Santa Creu i Sant Pau. Sant Antoni M. Claret, 167. 08025 Barcelona. España" ] ] ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Lobectomy versus limited resection to treat non-small cell lung cancer in stage I: a study of 78 cases" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2002-05-29" "fechaAceptado" => "2002-11-26" "PalabrasClave" => array:2 [ "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec190343" "palabras" => array:3 [ 0 => "Resección sublobar" 1 => "Resección en cuña" 2 => "Segmentectomía" ] ] ] "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Keywords" "identificador" => "xpalclavsec190344" "palabras" => array:3 [ 0 => "Sublobar resection" 1 => "Wedge resection" 2 => "Segmentectomy" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "es" => array:1 [ "resumen" => "<span class="elsevierStyleSectionTitle">Objetivo</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Comparar la tasa de mortalidad y recidiva locorregional de nuestra serie de pacientes intervenidos por un cáncer pulmonar no microcítico en estadio I durante el período 1994–1998, divididos en dos grupos: a) intervenidos de lobectomía, y b) intervenidos de resección pulmonar sublobar (cuña pulmonar)</p> <span class="elsevierStyleSectionTitle">Pacientes Y Métodos</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Se han revisado retrospectivamente 78 casos de resección pulmonar por cáncer pulmonar no microcítico en estadio I realizada entre enero de 1994 y diciembre de 1998: 50 sometidos a lobectomía y 28 a resección sublobar (cuña pulmonar). Se recogieron antecedentes oncológicos, histología de los tumores, recidiva locorregional y mortalidad relacionada con el tumor durante el período de seguimiento</p> <span class="elsevierStyleSectionTitle">Resultados</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">El estudio histológico de las lobectomías evidenció 36 carcinomas escamosos (72%), 12 adenocarcinomas (24%) y dos carcinomas de células grandes (4%). En el caso de las cuñas puso de manifiesto 12 carcinomas escamosos (42,8%) y 16 adenocarcinomas (57,2%). En cuanto a los estadios, en las lobectomías, en 15 (30%) era Ia y en 35 (70%) Ib, y en las cuñas, en 16 (57,2%) era Ia y en 12 (42,8%), Ib. Hubo recidiva locorregional en 9 lobectomías (18%) y en 4 cuñas (14,3%), más un caso de metástasis a distancia (3,6%). En cuanto a la mortalidad durante el seguimiento, fallecieron 8 pacientes (16%) sometidos a lobectomías y 4 (14,3%) sometidos a cuñas. La tasa de supervivencia acumulada (en meses) fue de 62,38 y 63,92 en lobectomías y cuñas, respectivamente. Los datos obtenidos no presentaron diferencias estadísticamente significativas en lo que se refiere a recidiva locorregional y supervivencia acumulada entre ambos grupos</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">En este trabajo las tasas de recidiva locorregional y supervivencia acumulada son concordantes con las de otros estudios retrospectivos. En nuestra serie no hallamos diferencias estadísticamente significativas entre los pacientes sometidos a lobectomía y los sometidos a resección sublobar. La resección en cuña resulta una técnica adecuada para aquellos pacientes con un carcinoma pulmonar no microcítico en estadio I que no pueden tolerar una lobectomía</p>" ] "en" => array:1 [ "resumen" => "<span class="elsevierStyleSectionTitle">Objective</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">To compare mortality and loco-regional recurrence rates in patients treated surgically for stage I non-small cell lung cancer by either lobectomy or sublobar lung resection (pulmonary wedge) from 1994 to 1998</p> <span class="elsevierStyleSectionTitle">Patients And Methods</span><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">Seventy-eight patients who underwent lung resection for stage I non-small cell lung cancer from January 1994 to December 1998 were reviewed retrospectively. Fifty patients underwent lobectomy and 28 limited resection (pulmonary wedge). We reviewed oncologic history, tumor histology, loco-regional recurrence and tumor-related mortality during the follow-up period</p> <span class="elsevierStyleSectionTitle">Results</span><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">Histology, lobectomies: 36 (72%) squamous cell carcinomas, 12 (24%) adenocarcinomas and 2 (4%) large cell carcinomas. Histology, wedge resection: 12 (42.8%) squamous cell carcinomas and 16 (57.2%) adenocarcinomas. Staging, lobectomies: 15 Ia (30%) and 35 Ib (70%). Staging, wedge resections: 16 Ia (57.2%) and 12 Ib (42.8%). Loco-regional recurrence: lobectomies 9 (18%) and wedge resections 4 (14.3%) plus 1 remote metastasis (3.6%). Mortality during follow-up: lobectomies 8 (16%) and wedge resections 4 (14.3%). Accumulated survival rate (in months): lobectomies 62.38 and wedge resections 63.92. The rates of loco-regional recurrence and accumulated survival in the two groups were not significantly different</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">The rates of loco-regional recurrence and accumulated survival in this study agree with those from other retrospective studies. We found no statistically significant differences between patients undergoing lobectomy and those undergoing sublobar resection. Wedge resection is an appropriate technique for patients with stage I non-small cell lung cancer who can not tolerate lobectomy</p>" ] ] "bibliografia" => array:2 [ "titulo" => "Bibliografía" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:22 [ 0 => array:3 [ "identificador" => "bib0005" "etiqueta" => "1." 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| Year/Month | Html | Total | |
|---|---|---|---|
| 2024 November | 10 | 12 | 22 |
| 2024 October | 39 | 36 | 75 |
| 2024 September | 39 | 47 | 86 |
| 2024 August | 54 | 55 | 109 |
| 2024 July | 35 | 43 | 78 |
| 2024 June | 49 | 41 | 90 |
| 2024 May | 44 | 60 | 104 |
| 2024 April | 30 | 33 | 63 |
| 2024 March | 45 | 48 | 93 |
| 2024 February | 36 | 51 | 87 |
| 2024 January | 0 | 4 | 4 |
| 2023 December | 0 | 6 | 6 |
| 2023 November | 0 | 10 | 10 |
| 2023 October | 0 | 8 | 8 |
| 2023 September | 0 | 2 | 2 |
| 2023 August | 0 | 3 | 3 |
| 2023 July | 0 | 2 | 2 |
| 2023 June | 0 | 1 | 1 |
| 2023 May | 0 | 4 | 4 |
| 2023 April | 0 | 2 | 2 |
| 2023 March | 10 | 4 | 14 |
| 2023 February | 31 | 36 | 67 |
| 2023 January | 20 | 43 | 63 |
| 2022 December | 26 | 54 | 80 |
| 2022 November | 29 | 31 | 60 |
| 2022 October | 27 | 52 | 79 |
| 2022 September | 22 | 41 | 63 |
| 2022 August | 38 | 58 | 96 |
| 2022 July | 26 | 62 | 88 |
| 2022 June | 27 | 63 | 90 |
| 2022 May | 37 | 46 | 83 |
| 2022 April | 32 | 49 | 81 |
| 2022 March | 30 | 66 | 96 |
| 2022 February | 34 | 41 | 75 |
| 2022 January | 32 | 40 | 72 |
| 2021 December | 15 | 46 | 61 |
| 2021 November | 25 | 66 | 91 |
| 2021 October | 33 | 38 | 71 |
| 2021 September | 23 | 74 | 97 |
| 2021 August | 16 | 45 | 61 |
| 2021 July | 26 | 45 | 71 |
| 2021 June | 13 | 39 | 52 |
| 2021 May | 20 | 48 | 68 |
| 2021 April | 25 | 77 | 102 |
| 2021 March | 36 | 34 | 70 |
| 2021 February | 49 | 31 | 80 |
| 2021 January | 37 | 42 | 79 |
| 2020 December | 28 | 30 | 58 |
| 2020 November | 14 | 25 | 39 |
| 2020 October | 12 | 36 | 48 |
| 2020 September | 20 | 20 | 40 |
| 2020 August | 22 | 7 | 29 |
| 2020 July | 27 | 26 | 53 |
| 2020 June | 19 | 19 | 38 |
| 2020 May | 19 | 19 | 38 |
| 2020 April | 30 | 32 | 62 |
| 2020 March | 32 | 43 | 75 |
| 2020 February | 25 | 33 | 58 |
| 2020 January | 34 | 37 | 71 |
| 2019 December | 31 | 36 | 67 |
| 2019 November | 10 | 23 | 33 |
| 2019 October | 13 | 18 | 31 |
| 2019 September | 10 | 25 | 35 |
| 2019 August | 23 | 17 | 40 |
| 2019 July | 20 | 39 | 59 |
| 2019 June | 16 | 32 | 48 |
| 2019 May | 38 | 27 | 65 |
| 2019 April | 37 | 28 | 65 |
| 2019 March | 10 | 18 | 28 |
| 2019 February | 9 | 11 | 20 |
| 2019 January | 11 | 10 | 21 |
| 2018 December | 14 | 13 | 27 |
| 2018 November | 24 | 9 | 33 |
| 2018 October | 28 | 13 | 41 |
| 2018 September | 23 | 10 | 33 |
| 2018 May | 6 | 1 | 7 |
| 2018 April | 11 | 5 | 16 |
| 2018 March | 8 | 9 | 17 |
| 2018 February | 7 | 9 | 16 |
| 2018 January | 9 | 8 | 17 |
| 2017 December | 9 | 13 | 22 |
| 2017 November | 1 | 10 | 11 |
| 2017 October | 11 | 21 | 32 |
| 2017 September | 13 | 15 | 28 |
| 2017 August | 11 | 13 | 24 |
| 2017 July | 20 | 20 | 40 |
| 2017 June | 17 | 23 | 40 |
| 2017 May | 13 | 29 | 42 |
| 2017 April | 7 | 12 | 19 |
| 2017 March | 5 | 32 | 37 |
| 2017 February | 4 | 12 | 16 |
| 2017 January | 7 | 11 | 18 |
| 2016 December | 16 | 8 | 24 |
| 2016 November | 25 | 23 | 48 |
| 2016 October | 29 | 20 | 49 |
| 2016 September | 31 | 21 | 52 |
| 2016 August | 16 | 6 | 22 |
| 2016 July | 27 | 12 | 39 |
| 2016 June | 27 | 14 | 41 |
| 2016 May | 26 | 11 | 37 |
| 2016 April | 18 | 2 | 20 |
| 2016 March | 12 | 3 | 15 |
| 2016 February | 9 | 3 | 12 |
| 2016 January | 32 | 24 | 56 |
| 2015 December | 38 | 23 | 61 |
| 2015 November | 32 | 7 | 39 |
| 2015 October | 126 | 1 | 127 |
| 2015 September | 94 | 0 | 94 |
| 2015 August | 94 | 0 | 94 |
| 2015 July | 99 | 0 | 99 |
| 2015 June | 107 | 0 | 107 |
| 2015 May | 125 | 0 | 125 |
| 2015 April | 107 | 0 | 107 |
| 2015 March | 110 | 0 | 110 |
| 2015 February | 89 | 0 | 89 |
| 2015 January | 79 | 0 | 79 |
| 2014 December | 84 | 0 | 84 |
| 2014 November | 103 | 0 | 103 |
| 2014 October | 119 | 0 | 119 |
| 2014 September | 105 | 0 | 105 |
| 2014 August | 127 | 0 | 127 |
| 2014 July | 114 | 0 | 114 |
| 2014 June | 169 | 0 | 169 |
| 2014 May | 168 | 0 | 168 |
| 2014 April | 162 | 0 | 162 |
| 2014 March | 147 | 0 | 147 |
| 2014 February | 114 | 0 | 114 |
| 2014 January | 92 | 0 | 92 |
| 2013 December | 90 | 0 | 90 |
| 2013 November | 96 | 0 | 96 |
| 2013 October | 106 | 0 | 106 |
| 2013 September | 100 | 0 | 100 |
| 2013 August | 78 | 0 | 78 |
| 2013 July | 99 | 0 | 99 |
| 2013 June | 74 | 0 | 74 |
| 2013 May | 65 | 0 | 65 |
| 2013 April | 58 | 0 | 58 |
| 2013 March | 12 | 0 | 12 |
| 2000 January | 2195 | 0 | 2195 |
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