Calcificación pulmonar metastásica: una rara causa de enfermedad pulmonar intersticial
Metastatic pulmonary calcification: a rare cause of interstitial lung disease
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López García-Gallo, P. Ussetti, B. Díaz, A. de Pablo, R. Laporta" "autores" => array:5 [ 0 => array:2 [ "nombre" => "C." "apellidos" => "López García-Gallo" ] 1 => array:2 [ "nombre" => "P." "apellidos" => "Ussetti" ] 2 => array:2 [ "nombre" => "B." "apellidos" => "Díaz" ] 3 => array:2 [ "nombre" => "A." "apellidos" => "de Pablo" ] 4 => array:2 [ "nombre" => "R." 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Masdeu, A. Ferrer" "autores" => array:2 [ 0 => array:2 [ "nombre" => "M.J." "apellidos" => "Masdeu" ] 1 => array:2 [ "nombre" => "A." "apellidos" => "Ferrer" ] ] ] ] ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S030028960375354X?idApp=UINPBA00003Z" "url" => "/03002896/0000003900000004/v1_201307081453/S030028960375354X/v1_201307081453/es/main.assets" ] "es" => array:14 [ "idiomaDefecto" => true "titulo" => "Calcificación pulmonar metastásica: una rara causa de enfermedad pulmonar intersticial" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "184" "paginaFinal" => "186" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "R. Santiago Villalobos, E. Rodríguez Becerra, F. Borderas Naranjo, J. Martín Juan" "autores" => array:4 [ 0 => array:4 [ "nombre" => "R." "apellidos" => "Santiago Villalobos" "email" => array:1 [ 0 => "rsantiago_villalobos@hotmail.com" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">¿</span>" "identificador" => "cor0005" ] ] ] 1 => array:3 [ "nombre" => "E." "apellidos" => "Rodríguez Becerra" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] ] ] 2 => array:3 [ "nombre" => "F." "apellidos" => "Borderas Naranjo" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] ] 3 => array:3 [ "nombre" => "J." "apellidos" => "Martín Juan" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] ] ] ] "afiliaciones" => array:2 [ 0 => array:3 [ "entidad" => "Unidad Médico-Quirúrgica de Enfermedades Respiratorias. Hospital Universitario Virgen del Rocío. Sevilla" "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "Departamento de Anatomía Patológica. Hospital Universitario Virgen del Rocío. Sevilla. España" "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Correspondencia: Bami, 27, 4.° D. 41013 Sevilla. España" ] ] ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Metastatic pulmonary calcification: a rare cause of interstitial lung disease" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2002-09-25" "fechaAceptado" => "2002-10-23" "PalabrasClave" => array:2 [ "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec190383" "palabras" => array:3 [ 0 => "Enfermedad pulmonar intersticial" 1 => "Calcificación pulmonar metastásica" 2 => "Calcinosis pulmonar metastásica" ] ] ] "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Keywords" "identificador" => "xpalclavsec190384" "palabras" => array:3 [ 0 => "Interstitial pulmonary disease" 1 => "Metastatic pulmo-nary calcification" 2 => "Metastatic pulmonary calcinosis" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "es" => array:1 [ "resumen" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Presentamos el caso de una paciente de 58 años diagnosti-cada de calcinosis pulmonar metastásica. Clínicamente refe-ría síntomas de hiperreactividad bronquial. Tras tiroidecto-mía total bilateral con paratiroidectomía, estaba en tratamiento sustitutivo con calcio y vitamina D, y presentó 4 episodios de hipercalcemia sintomática secundaria a admi-nistración exógena. Las pruebas de función pulmonar evi-denciaban un patrón obstructivo leve con reversibilidad tras broncodilatadores. Las pruebas de imagen ponían de mani-fiesto un patrón micronodular bilateral de predominio en campos superiores (radiografía y tomografía computarizada de alta resolución de tórax), y depósito patológico de calcio en el pulmón (gammagrafía ósea). El diagnóstico se estable-ció mediante biopsia transbronquial. La evolución de la pa-ciente fue favorable</p><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">La calcinosis pulmonar metastásica es una afección rara, generalmente asintomática y de buena evolución, que habría que tener presente en el diagnóstico diferencial de las neu-mopatías intersticiales de morfología micronodular en pa-cientes con factores de riesgo para su desarrollo</p>" ] "en" => array:1 [ "resumen" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">We report the case of a 58-year-old woman with metasta-tic pulmonary calcinosis who presented with bronchial hy-perreactivity. She was receiving calcium and vitamin D sup-plementation following total bilateral thyroidectomy with parathyroidectomy and had a history of episodes of sympto-matic hypercalcemia secondary to exogenous administra-tion. Lung function testing showed slight obstruction that was reversed by bronchodilators. Images showed a bilateral micronodular pattern mainly in the upper fields (x-ray and high resolution computed tomography of the thorax) and abnormal calcium deposition in the lungs (bone scinti-graphy). The diagnosis was established by transbronchial biopsy. The clinical course was favorable. Metastatic pulmo-nary calcinosis is rare and usually asymptomatic and evolu-tion is good. This entity should be taken into account in the differential diagnosis of interstitial lung diseases involving micronodular infiltrates in patients at risk</p>" ] ] "bibliografia" => array:2 [ "titulo" => "Bibliografía" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:4 [ 0 => array:3 [ "identificador" => "bib0005" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Diffuse pulmonary nodular infiltrates in a renal transplant recipient" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:3 [ 0 => "E. Ulmer" 1 => "H. Borer" 2 => "P. Sandoz" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Chest" "fecha" => "2000" "volumen" => "120" "paginaInicial" => "1394" "paginaFinal" => "1398" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11591586" "web" => "Medline" ] ] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib0010" "etiqueta" => "2." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Case report. Metastatic pulmonary calcification in renal failure: a new HRCT pattern" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "R.K. Lingam" 1 => "J. The" 2 => "A. Sharma" 3 => "E. Friedman" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1259/bjr.75.889.750074" "Revista" => array:6 [ "tituloSerie" => "Br J Radiol" "fecha" => "2002" "volumen" => "75" "paginaInicial" => "74" "paginaFinal" => "77" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11806963" "web" => "Medline" ] ] ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib0015" "etiqueta" => "3." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Diffuse pulmonary calcinosis without calcium metabolism abnormalities in a renal transplant recipient" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "M. Romagnoli" 1 => "G. Mourad" 2 => "I. Serre" 3 => "J.P. Senac" 4 => "L. Paradis" 5 => "P. Godard" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Eur Respir J" "fecha" => "1997" "volumen" => "10" "paginaInicial" => "958" "paginaFinal" => "960" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9150342" "web" => "Medline" ] ] ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib0020" "etiqueta" => "4." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "State of the art: calcium deposition with or without bone formation in the lung" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "E.D. Chan" 1 => "D.V. Morales" 2 => "C.H. Welsh" 3 => "M.T. McDermott" 4 => "M.I. Schwarz" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1164/rccm.2108054" "Revista" => array:6 [ "tituloSerie" => "Am J Respir Crit Care Med" "fecha" => "2002" "volumen" => "165" "paginaInicial" => "1654" "paginaFinal" => "1669" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12070068" "web" => "Medline" ] ] ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "es" "url" => "/03002896/0000003900000004/v1_201307081453/S0300289603753551/v1_201307081453/es/main.assets" "Apartado" => array:4 [ "identificador" => "9217" "tipo" => "SECCION" "es" => array:2 [ "titulo" => "Notas clínicas" "idiomaDefecto" => true ] "idiomaDefecto" => "es" ] "PDF" => "https://static.elsevier.es/multimedia/03002896/0000003900000004/v1_201307081453/S0300289603753551/v1_201307081453/es/main.pdf?idApp=UINPBA00003Z&text.app=https://archbronconeumol.org/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289603753551?idApp=UINPBA00003Z" ]
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