Edema agudo de pulmón no cardiogénico secundario a hidroclorotiazida
Acute non-cardiogenic pulmonary edema secondary to hydrochlorothiazide therapy
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"apellidos" => "Jara Chinarro" "email" => array:1 [ 0 => "beat1089@separ.es" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor0005" ] ] ] 1 => array:3 [ "nombre" => "J." "apellidos" => "De Miguel Díez" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] ] 2 => array:3 [ "nombre" => "J.L." "apellidos" => "García Satue" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] ] ] 3 => array:3 [ "nombre" => "M.A." "apellidos" => "Juretschke Moragues" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] ] ] 4 => array:3 [ "nombre" => "J.A." "apellidos" => "Serrano Iglesias" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] ] ] ] "afiliaciones" => array:2 [ 0 => array:3 [ "entidad" => "Servicio de Neumología. Hospital Universitario de Getafe. Getafe. Madrid" "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "Servicio de Neumología. Hospital Universitario Gregorio Marañón. Madrid. España" "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "*" "correspondencia" => "Correspondencia: Servicio de Neumología. Hospital Universitario de Getafe.Ctra. de Toledo, Km 12,500. 28905 Getafe. Madrid. España" ] ] ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Acute non-cardiogenic pulmonary edema secondary to hydrochlorothiazide therapy" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2002-07-10" "fechaAceptado" => "2002-10-08" "PalabrasClave" => array:2 [ "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec190520" "palabras" => array:3 [ 0 => "Edema de pulmón no cardiogénico" 1 => "Hidroclorotiazida" 2 => "Reacción a fármacos" ] ] ] "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Keywords" "identificador" => "xpalclavsec190519" "palabras" => array:5 [ 0 => "Non-cardiogenic pulmonary edema" 1 => "Hydrochlorothiazide" 2 => "Pharmacology" 3 => "side effect" 4 => "adverse reaction" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "es" => array:1 [ "resumen" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Diversos fármacos utilizados con asiduidad pueden pro-ducir edema agudo de pulmón no cardiogénico. En la mayo-ría de los casos es difícil establecer la relación causal por la inespecificidad de los síntomas. Presentamos el caso clínico de un edema pulmonar inducido por un diurético de uso fre-cuente, la hidroclorotiazida. Esta complicación puede pre-sentarse tras la primera toma del fármaco, o aparecer en pacientes que lo habían tomado previamente sin problemas. Se debe a una reacción idiosincrásica, no inmunitaria. La evolución suele ser favorable en las primeras 14 h con trata-miento de soporte respiratorio y hemodinámico. En caso de recurrencia, aumenta la gravedad, por lo que señalamos la importancia del diagnóstico en el primer episodio</p>" ] "en" => array:1 [ "resumen" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Several commonly prescribed drugs can cause acute non-cardiogenic pulmonary edema. A cause-effect relationship is usually difficult to establish because symptoms are not specific. We report a case of pulmonary edema induced by a common diuretic, hydrochlorothiazide. This complication can occur after a first dose of the drug or in patients who have been taking it with no side effects. Edema is due to an idiosyncratic reaction rather than an immune response. The clinical course is usually favorable over the first 24 hours with treatment of blood pressure and respiratory support. Given that severity increases with recurrence, we underline the importance of diagnosis in the first episode</p>" ] ] "bibliografia" => array:2 [ "titulo" => "Bibliografía" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:14 [ 0 => array:3 [ "identificador" => "bib0005" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Diagnosis and management of acute lung injury" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "W.A. 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| 2019 January | 18 | 19 | 37 |
| 2018 December | 27 | 38 | 65 |
| 2018 November | 34 | 43 | 77 |
| 2018 October | 51 | 50 | 101 |
| 2018 September | 39 | 61 | 100 |
| 2018 May | 18 | 3 | 21 |
| 2018 April | 27 | 5 | 32 |
| 2018 March | 7 | 8 | 15 |
| 2018 February | 7 | 9 | 16 |
| 2018 January | 12 | 20 | 32 |
| 2017 December | 9 | 33 | 42 |
| 2017 November | 10 | 46 | 56 |
| 2017 October | 8 | 55 | 63 |
| 2017 September | 8 | 50 | 58 |
| 2017 August | 12 | 47 | 59 |
| 2017 July | 5 | 52 | 57 |
| 2017 June | 18 | 63 | 81 |
| 2017 May | 24 | 40 | 64 |
| 2017 April | 5 | 30 | 35 |
| 2017 March | 30 | 46 | 76 |
| 2017 February | 4 | 76 | 80 |
| 2017 January | 3 | 35 | 38 |
| 2016 December | 18 | 38 | 56 |
| 2016 November | 26 | 86 | 112 |
| 2016 October | 22 | 83 | 105 |
| 2016 September | 30 | 123 | 153 |
| 2016 August | 45 | 40 | 85 |
| 2016 July | 42 | 31 | 73 |
| 2016 June | 29 | 27 | 56 |
| 2016 May | 40 | 42 | 82 |
| 2016 April | 12 | 6 | 18 |
| 2016 March | 6 | 3 | 9 |
| 2016 February | 12 | 4 | 16 |
| 2016 January | 32 | 21 | 53 |
| 2015 December | 28 | 16 | 44 |
| 2015 November | 36 | 12 | 48 |
| 2015 October | 779 | 1 | 780 |
| 2015 September | 893 | 0 | 893 |
| 2015 August | 775 | 0 | 775 |
| 2015 July | 817 | 0 | 817 |
| 2015 June | 855 | 0 | 855 |
| 2015 May | 1107 | 0 | 1107 |
| 2015 April | 797 | 0 | 797 |
| 2015 March | 855 | 0 | 855 |
| 2015 February | 692 | 0 | 692 |
| 2015 January | 515 | 0 | 515 |
| 2014 December | 492 | 0 | 492 |
| 2014 November | 600 | 0 | 600 |
| 2014 October | 848 | 0 | 848 |
| 2014 September | 664 | 0 | 664 |
| 2014 August | 473 | 0 | 473 |
| 2014 July | 463 | 0 | 463 |
| 2014 June | 507 | 0 | 507 |
| 2014 May | 609 | 0 | 609 |
| 2014 April | 556 | 0 | 556 |
| 2014 March | 440 | 0 | 440 |
| 2014 February | 410 | 0 | 410 |
| 2014 January | 314 | 0 | 314 |
| 2013 December | 224 | 0 | 224 |
| 2013 November | 215 | 0 | 215 |
| 2013 October | 236 | 0 | 236 |
| 2013 September | 306 | 0 | 306 |
| 2013 August | 234 | 0 | 234 |
| 2013 July | 190 | 0 | 190 |
| 2013 June | 126 | 0 | 126 |
| 2013 May | 178 | 0 | 178 |
| 2013 April | 85 | 0 | 85 |
| 2013 March | 39 | 0 | 39 |
| 2000 January | 10077 | 0 | 10077 |
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