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        "resumen" => "<span class="elsevierStyleSectionTitle">Objetivos</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Estudiar los criterios diagn&#243;sticos de la fibro-sis pulmonar idiop&#225;tica seg&#250;n el &#250;ltimo Consenso Interna-cional</p> <span class="elsevierStyleSectionTitle">Pacientes Y M&#233;todo</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Se incluy&#243; a todos los pacientes diagnosticados de cualquier enfermedad intersticial por me-dio de biopsia pulmonar abierta desde 1980&#46; Se revisaron sus historias cl&#237;nicas para averiguar si cumpl&#237;an los criterios diagn&#243;sticos&#44; as&#237; como sus biopsias pulmonares en busca del patr&#243;n de neumon&#237;a intersticial usual&#46; Se calcularon la sen-sibilidad&#44; la especificidad&#44; los valores predictivos positivo y negativo y los cocientes de probabilidad&#46; Posteriormente&#44; se realiz&#243; el mismo an&#225;lisis requiriendo s&#243;lo una de las dos condiciones funcionales para cumplir el criterio funcional</p> <span class="elsevierStyleSectionTitle">Resultados</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Se incluy&#243; a 39 pacientes&#44; 17 de los cuales presentaban una fibrosis pulmonar idiop&#225;tica&#46; La especifici-dad y el valor predictivo positivo fue del 100&#37;&#44; mientras que la sensibilidad y el valor predictivo negativo fueron del 41&#44;2 y del 68&#44;7&#37;&#44; respectivamente&#46; El cociente de probabili-dad para un resultado negativo fue de 0&#44;59&#46; En el segundo an&#225;lisis&#44; la sensibilidad y el valor predictivo negativo fueron del 64&#44;7 y del 78&#44;5&#37;&#44; respectivamente&#44; con id&#233;ntica especifi-cidad y valor predictivo positivo&#46; El cociente de probabili-dad para un resultado negativo fue de 0&#44;35</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">Los criterios diagn&#243;sticos son lo suficien-temente espec&#237;ficos como para estar seguros del diagn&#243;stico cuando se cumplen&#46; Deber&#237;a considerarse un peque&#241;o cam-bio en el criterio funcional para aumentar la rentabilidad del diagn&#243;stico</p>"
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        "resumen" => "<span class="elsevierStyleSectionTitle">Objectives</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">To analyze the international consensus state-ment on diagnostic criteria for idiopathic pulmonary fibro-sis</p> <span class="elsevierStyleSectionTitle">Methods</span><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">All patients diagnosed of any interstitial lung disease by means of open lung biopsy since 1980 were inclu-ded&#46; The patients&#39; clinical records were examined to deter-mine whether they fulfilled the diagnostic criteria&#44; and their biopsies were reviewed to find those with the usual intersti-tial pneumonia pattern&#46; We calculated sensitivity&#44; specifi-city&#44; positive and negative predictive values and likelihood ratios for the diagnostic criteria in the consensus statement&#46; Afterwards&#44; we performed the analyses again using only one of the two conditions for fulfilling the function criterion</p> <span class="elsevierStyleSectionTitle">Results</span><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">Of 39 patients enrolled in the study&#44; 17 had idio-pathic pulmonary fibrosis&#46; Specificity and positive predicti-ve value were both 100&#37;&#44; but sensitivity was 41&#46;2&#37; and ne-gative predictive value was 68&#46;7&#37;&#46; The likelihood ratio for a negative result was 0&#46;59&#46; In the second analysis&#44; sensitivity was 64&#46;7&#37; and negative predictive value was 78&#46;5&#37;&#44; while specificity and positive predictive value remained unchan-ged&#46; The likelihood ratio for a negative result was 0&#46;35</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">The criteria are sufficiently specific to allow us to diagnose confidently when the criteria are fulfi-lled&#46; However&#44; a slight change in the function criterion should be considered in order to increase diagnostic yield</p>"
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Evaluación de los criterios diagnósticos clínicos de fibrosis pulmonar idiopática
Evaluation of clinical diagnostic guidelines for idiopathic pulmonary fibrosis
J.L. López-Campos Bodineaua,
Corresponding author
lcampos@hcs.es

Correspondencia: Avda. Reina Mercedes, 35, 6.° D. 41012 Sevilla. España
, L. Gómez Izquierdob, E. Rodríguez Becerraa, J. Martín Juana, M. Fajardo Cascosc, F. Borderas Naranjob, J. Castillo Gómeza
a Unidad Médico-Quirúrgica de Enfermedades Respiratorias. Hospital Universitario Virgen del Rocio. Sevilla. España
b Servicio de Anatomía Patológica. Hospital Universitario Virgen del Rocío. Sevilla. España
c Servicio de Radiodiagnóstico. Hospital Universitario Virgen del Rocío. Sevilla. España
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        "resumen" => "<span class="elsevierStyleSectionTitle">Objetivos</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Estudiar los criterios diagn&#243;sticos de la fibro-sis pulmonar idiop&#225;tica seg&#250;n el &#250;ltimo Consenso Interna-cional</p> <span class="elsevierStyleSectionTitle">Pacientes Y M&#233;todo</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Se incluy&#243; a todos los pacientes diagnosticados de cualquier enfermedad intersticial por me-dio de biopsia pulmonar abierta desde 1980&#46; Se revisaron sus historias cl&#237;nicas para averiguar si cumpl&#237;an los criterios diagn&#243;sticos&#44; as&#237; como sus biopsias pulmonares en busca del patr&#243;n de neumon&#237;a intersticial usual&#46; Se calcularon la sen-sibilidad&#44; la especificidad&#44; los valores predictivos positivo y negativo y los cocientes de probabilidad&#46; Posteriormente&#44; se realiz&#243; el mismo an&#225;lisis requiriendo s&#243;lo una de las dos condiciones funcionales para cumplir el criterio funcional</p> <span class="elsevierStyleSectionTitle">Resultados</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Se incluy&#243; a 39 pacientes&#44; 17 de los cuales presentaban una fibrosis pulmonar idiop&#225;tica&#46; La especifici-dad y el valor predictivo positivo fue del 100&#37;&#44; mientras que la sensibilidad y el valor predictivo negativo fueron del 41&#44;2 y del 68&#44;7&#37;&#44; respectivamente&#46; El cociente de probabili-dad para un resultado negativo fue de 0&#44;59&#46; En el segundo an&#225;lisis&#44; la sensibilidad y el valor predictivo negativo fueron del 64&#44;7 y del 78&#44;5&#37;&#44; respectivamente&#44; con id&#233;ntica especifi-cidad y valor predictivo positivo&#46; El cociente de probabili-dad para un resultado negativo fue de 0&#44;35</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">Los criterios diagn&#243;sticos son lo suficien-temente espec&#237;ficos como para estar seguros del diagn&#243;stico cuando se cumplen&#46; Deber&#237;a considerarse un peque&#241;o cam-bio en el criterio funcional para aumentar la rentabilidad del diagn&#243;stico</p>"
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        "resumen" => "<span class="elsevierStyleSectionTitle">Objectives</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">To analyze the international consensus state-ment on diagnostic criteria for idiopathic pulmonary fibro-sis</p> <span class="elsevierStyleSectionTitle">Methods</span><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">All patients diagnosed of any interstitial lung disease by means of open lung biopsy since 1980 were inclu-ded&#46; The patients&#39; clinical records were examined to deter-mine whether they fulfilled the diagnostic criteria&#44; and their biopsies were reviewed to find those with the usual intersti-tial pneumonia pattern&#46; We calculated sensitivity&#44; specifi-city&#44; positive and negative predictive values and likelihood ratios for the diagnostic criteria in the consensus statement&#46; Afterwards&#44; we performed the analyses again using only one of the two conditions for fulfilling the function criterion</p> <span class="elsevierStyleSectionTitle">Results</span><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">Of 39 patients enrolled in the study&#44; 17 had idio-pathic pulmonary fibrosis&#46; Specificity and positive predicti-ve value were both 100&#37;&#44; but sensitivity was 41&#46;2&#37; and ne-gative predictive value was 68&#46;7&#37;&#46; The likelihood ratio for a negative result was 0&#46;59&#46; In the second analysis&#44; sensitivity was 64&#46;7&#37; and negative predictive value was 78&#46;5&#37;&#44; while specificity and positive predictive value remained unchan-ged&#46; The likelihood ratio for a negative result was 0&#46;35</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">The criteria are sufficiently specific to allow us to diagnose confidently when the criteria are fulfi-lled&#46; However&#44; a slight change in the function criterion should be considered in order to increase diagnostic yield</p>"
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ISSN: 03002896
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