Síndrome de bajo peso asociado a la EPOC en nuestro medio
Low-weight syndrome associated with COPD in our setting
C. Coronell, M. Orozco-Levi, A. Ramírez-Sarmiento, J. Martínez-Llorens, J. Broquetas, J. Gea
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jgea@imim.es
Correspondencia: Servei de Pneumologia. Hospital del Mar-Imim. P.° Marítim, 27. 08003 Barcelona. España
Correspondencia: Servei de Pneumologia. Hospital del Mar-Imim. P.° Marítim, 27. 08003 Barcelona. España
Servicio de Neumología. Hospital del Mar-Imim. Universidades Pompeu Fabra (UPF) y Autónoma (UAB). Barcelona. España
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Gea" "autores" => array:6 [ 0 => array:2 [ "nombre" => "C." "apellidos" => "Coronell" ] 1 => array:2 [ "nombre" => "M." "apellidos" => "Orozco-Levi" ] 2 => array:2 [ "nombre" => "A." "apellidos" => "Ramírez-Sarmiento" ] 3 => array:2 [ "nombre" => "J." "apellidos" => "Martínez-Llorens" ] 4 => array:2 [ "nombre" => "J." "apellidos" => "Broquetas" ] 5 => array:4 [ "nombre" => "J." "apellidos" => "Gea" "email" => array:1 [ 0 => "jgea@imim.es" ] "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor0005" ] ] ] ] "afiliaciones" => array:1 [ 0 => array:1 [ "entidad" => "Servicio de Neumología. Hospital del Mar-Imim. Universidades Pompeu Fabra (UPF) y Autónoma (UAB). Barcelona. España" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "*" "correspondencia" => "Correspondencia: Servei de Pneumologia. Hospital del Mar-Imim. P.° Marítim, 27. 08003 Barcelona. España" ] ] ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Low-weight syndrome associated with COPD in our setting" ] ] "miscelanea" => "El Dr. Coronel es beneficiario de una Beca para Movilización de Científicos Extranjeros del Ministerio de Educación y Cultura de España" "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2002-05-02" "fechaAceptado" => "2002-06-25" "PalabrasClave" => array:2 [ "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec190636" "palabras" => array:3 [ 0 => "EPOC" 1 => "Nutrición" 2 => "Fenotipo" ] ] ] "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Keywords" "identificador" => "xpalclavsec190635" "palabras" => array:3 [ 0 => "COPD" 1 => "Nutrition" 2 => "Patient characteristics" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "es" => array:1 [ "resumen" => "<span class="elsevierStyleSectionTitle">Introducción</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">La enfermedad pulmonar obstructiva crónica (EPOC) es una entidad de elevada prevalencia, con importantes consecuencias económicas y sanitarias, que derivan en gran parte de la limitación que la enfermedad comporta en la actividad y expectativas vitales del paciente. Uno de los factores recientemente implicados en las citadas limitaciones es la presencia de bajo peso asociada con la enfermedad. Aunque la causa no está clara, esta alteración parece afectar a un número importante de pacientes (entre el 25 y el 35% según las series), al menos en el norte de Europa y los EE.UU. Sin embargo, existe la percepción de que la situación podría ser diferente en el área mediterránea.</p> <span class="elsevierStyleSectionTitle">Objetivo</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Aproximar la prevalencia del síndrome de bajo peso en pacientes con EPOC de nuestro entorno.</p> <span class="elsevierStyleSectionTitle">Método</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Se revisaron las características antropométricas básicas de los pacientes con EPOC filiados funcionalmente en nuestro laboratorio a lo largo de los dos últimos años (2000–2001).</p> <span class="elsevierStyleSectionTitle">Resultados</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">De los 3.126 sujetos analizados, la prevalencia de un índice de masa corporal (IMC) por debajo de 20 kg/m<span class="elsevierStyleSup">2</span>fue de tan sólo el 6,6%, cifra que se reducía al 3,1% si el dintel escogido era el de 18 kg/m<span class="elsevierStyleSup">2</span>. Este dato es aún más llamativo si se tiene en cuenta que casi la mitad de los pacientes evidenciaban enfermedad grave (volumen espiratorio forzado en el primer segundo [FEV<span class="elsevierStyleInf">1</span>] inferior al 50% ref). El IMC se correlacionó directamente con FEV<span class="elsevierStyleInf">1</span>/FVC y transferencia del CO.</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">Estos resultados sugieren que los pacientes con EPOC de nuestra área geográfica presentan características fenotípicas diferenciadas de las previamente descritas en otras latitudes. En concreto, una menor prevalencia del síndrome de bajo peso. Sin embargo, esta observación debe ser confirmada en estudios más amplios.</p>" ] "en" => array:1 [ "resumen" => "<p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">The high prevalence of chronic obstructive pulmonary disease (COPD) has considerable economic and health-related impact. The consequences arise largely from limitations on a patient's activity and shortened life expectancy. Low body weight has recently been implicated as a factor affecting limitations. Although the reason is not clear, weight loss appears to affect many patients (from 25 to 35% in different series), at least in Europe and North America. However, the situation is thought to be different in the Mediterranean area.</p> <span class="elsevierStyleSectionTitle">Objective</span><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">To estimate the prevalence of the low weight syndrome in patients with COPD in our area.</p> <span class="elsevierStyleSectionTitle">Method</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">COPD patient characteristics monitored by our laboratory over the last two years (2000 and 2001) were reviewed.</p> <span class="elsevierStyleSectionTitle">Results</span><p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">The prevalence of a body mass index (BMI) less than 20 kg/m<span class="elsevierStyleSup">2</span>was only 6.6% among the 3,126 patients studied. That percentage fell to 3.1% with a cutoff of 18 kg/m<span class="elsevierStyleSup">2</span>. The figure was even more striking if we consider that half the patients had severe disease (FEV 1<50% of reference). BMI was directly related to FEV<span class="elsevierStyleInf">1</span>/FC and CO transfer.</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p id="spar0050" class="elsevierStyleSimplePara elsevierViewall">These results suggest that COPD patients in our geographic area have characteristics that distinguish them from those previously described in other countries. Specifically, the prevalence of low weight syndrome in our area appears to be lower. However, larger studies should be performed to confirm this finding.</p>" ] ] "NotaPie" => array:1 [ 0 => array:1 [ "nota" => "<p class="elsevierStyleNotepara">Subvencionado por Biomed Bmh4-CT98-3406 (Unión Europea), FIS 01/1324 y SEPAR 2001</p>" ] ] "bibliografia" => array:2 [ "titulo" => "Bibliografía" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:26 [ 0 => array:3 [ "identificador" => "bib0005" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Geographic variations in prevalence and underdiagnosis of COPD: results of the IBERPOC multicentre epidemiological study" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "V.S. Pena" 1 => "M. Miravitlles" 2 => "R. Gabriel" 3 => "C.A. Jimenez-ruiz" 4 => "C. Villasante" 5 => "J.F. 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| Year/Month | Html | Total | |
|---|---|---|---|
| 2024 November | 3 | 3 | 6 |
| 2024 October | 40 | 24 | 64 |
| 2024 September | 38 | 20 | 58 |
| 2024 August | 50 | 33 | 83 |
| 2024 July | 43 | 27 | 70 |
| 2024 June | 53 | 26 | 79 |
| 2024 May | 44 | 33 | 77 |
| 2024 April | 29 | 17 | 46 |
| 2024 March | 53 | 32 | 85 |
| 2024 February | 35 | 34 | 69 |
| 2023 December | 0 | 1 | 1 |
| 2023 November | 0 | 2 | 2 |
| 2023 October | 0 | 2 | 2 |
| 2023 July | 0 | 8 | 8 |
| 2023 June | 0 | 14 | 14 |
| 2023 March | 5 | 4 | 9 |
| 2023 February | 27 | 12 | 39 |
| 2023 January | 32 | 22 | 54 |
| 2022 December | 35 | 24 | 59 |
| 2022 November | 38 | 20 | 58 |
| 2022 October | 30 | 27 | 57 |
| 2022 September | 23 | 42 | 65 |
| 2022 August | 48 | 40 | 88 |
| 2022 July | 23 | 27 | 50 |
| 2022 June | 21 | 43 | 64 |
| 2022 May | 37 | 31 | 68 |
| 2022 April | 44 | 29 | 73 |
| 2022 March | 45 | 30 | 75 |
| 2022 February | 37 | 34 | 71 |
| 2022 January | 23 | 39 | 62 |
| 2021 December | 21 | 44 | 65 |
| 2021 November | 28 | 45 | 73 |
| 2021 October | 20 | 43 | 63 |
| 2021 September | 28 | 47 | 75 |
| 2021 August | 21 | 45 | 66 |
| 2021 July | 33 | 38 | 71 |
| 2021 June | 31 | 38 | 69 |
| 2021 May | 22 | 36 | 58 |
| 2021 April | 58 | 66 | 124 |
| 2021 March | 40 | 25 | 65 |
| 2021 February | 71 | 17 | 88 |
| 2021 January | 35 | 25 | 60 |
| 2020 December | 29 | 23 | 52 |
| 2020 November | 26 | 14 | 40 |
| 2020 October | 33 | 17 | 50 |
| 2020 September | 33 | 9 | 42 |
| 2020 August | 54 | 8 | 62 |
| 2020 July | 47 | 24 | 71 |
| 2020 June | 31 | 15 | 46 |
| 2020 May | 28 | 16 | 44 |
| 2020 April | 35 | 16 | 51 |
| 2020 March | 30 | 18 | 48 |
| 2020 February | 36 | 14 | 50 |
| 2020 January | 60 | 26 | 86 |
| 2019 December | 24 | 24 | 48 |
| 2019 November | 19 | 14 | 33 |
| 2019 October | 25 | 13 | 38 |
| 2019 September | 23 | 23 | 46 |
| 2019 August | 25 | 7 | 32 |
| 2019 July | 43 | 29 | 72 |
| 2019 June | 34 | 30 | 64 |
| 2019 May | 56 | 47 | 103 |
| 2019 April | 26 | 36 | 62 |
| 2019 March | 17 | 15 | 32 |
| 2019 February | 18 | 11 | 29 |
| 2019 January | 10 | 11 | 21 |
| 2018 December | 18 | 29 | 47 |
| 2018 November | 23 | 16 | 39 |
| 2018 October | 48 | 13 | 61 |
| 2018 September | 23 | 6 | 29 |
| 2018 May | 12 | 1 | 13 |
| 2018 April | 5 | 12 | 17 |
| 2018 March | 16 | 11 | 27 |
| 2018 February | 17 | 10 | 27 |
| 2018 January | 12 | 10 | 22 |
| 2017 December | 12 | 11 | 23 |
| 2017 November | 14 | 12 | 26 |
| 2017 October | 12 | 14 | 26 |
| 2017 September | 11 | 7 | 18 |
| 2017 August | 10 | 9 | 19 |
| 2017 July | 11 | 6 | 17 |
| 2017 June | 27 | 19 | 46 |
| 2017 May | 11 | 17 | 28 |
| 2017 April | 9 | 7 | 16 |
| 2017 March | 12 | 13 | 25 |
| 2017 February | 4 | 10 | 14 |
| 2017 January | 15 | 14 | 29 |
| 2016 December | 37 | 12 | 49 |
| 2016 November | 50 | 19 | 69 |
| 2016 October | 58 | 32 | 90 |
| 2016 September | 47 | 15 | 62 |
| 2016 August | 34 | 9 | 43 |
| 2016 July | 30 | 4 | 34 |
| 2016 June | 42 | 13 | 55 |
| 2016 May | 34 | 11 | 45 |
| 2016 April | 31 | 2 | 33 |
| 2016 March | 19 | 3 | 22 |
| 2016 February | 26 | 4 | 30 |
| 2016 January | 44 | 15 | 59 |
| 2015 December | 54 | 16 | 70 |
| 2015 November | 51 | 9 | 60 |
| 2015 October | 80 | 1 | 81 |
| 2015 September | 73 | 0 | 73 |
| 2015 August | 84 | 0 | 84 |
| 2015 July | 81 | 0 | 81 |
| 2015 June | 67 | 0 | 67 |
| 2015 May | 115 | 0 | 115 |
| 2015 April | 62 | 0 | 62 |
| 2015 March | 65 | 0 | 65 |
| 2015 February | 39 | 0 | 39 |
| 2015 January | 51 | 0 | 51 |
| 2014 December | 48 | 0 | 48 |
| 2014 November | 71 | 0 | 71 |
| 2014 October | 78 | 0 | 78 |
| 2014 September | 40 | 0 | 40 |
| 2014 August | 72 | 0 | 72 |
| 2014 July | 56 | 0 | 56 |
| 2014 June | 70 | 0 | 70 |
| 2014 May | 71 | 0 | 71 |
| 2014 April | 60 | 0 | 60 |
| 2014 March | 62 | 0 | 62 |
| 2014 February | 66 | 0 | 66 |
| 2014 January | 67 | 0 | 67 |
| 2013 December | 50 | 0 | 50 |
| 2013 November | 48 | 0 | 48 |
| 2013 October | 47 | 0 | 47 |
| 2013 September | 41 | 0 | 41 |
| 2013 August | 69 | 0 | 69 |
| 2013 July | 69 | 0 | 69 |
| 2013 June | 34 | 0 | 34 |
| 2013 May | 39 | 0 | 39 |
| 2013 April | 27 | 0 | 27 |
| 2013 March | 12 | 0 | 12 |
| 2000 January | 3019 | 0 | 3019 |
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