Calidad de los ensayos clínicos publicados en España sobre el asma: comparación con los ensayos clínicos publicados en revistas anglosajonas
Quality of clinical trials published in Spain on asthma in comparison to trials in English language journals
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España" ] ] ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Quality of clinical trials published in Spain on asthma in comparison to trials in English language journals" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2002-07-22" "fechaAceptado" => "2002-10-15" "PalabrasClave" => array:2 [ "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec190641" "palabras" => array:3 [ 0 => "Asma" 1 => "Ensayo clínico controlado" 2 => "Método epidemiológico" ] ] ] "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Keywords" "identificador" => "xpalclavsec190642" "palabras" => array:3 [ 0 => "Asthma" 1 => "Controlled clinical trial" 2 => "Epidemiological methodology" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "es" => array:1 [ "resumen" => "<span class="elsevierStyleSectionTitle">Objetivos</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Evaluar la calidad de los ensayos clínicos sobre asma publicados en revistas españolas y compararla con los publicados en revistas anglosajonas.</p> <span class="elsevierStyleSectionTitle">Método</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Los ensayos clínicos se obtuvieron por búsqueda en Medline e Índice Médico Español, completando con búsqueda manual a partir de los artículos previamente seleccionados. La calidad se evaluó mediante la escala propuesta por Detsky et al (J Clin Epidemiol 1992;45:255-65).</p> <span class="elsevierStyleSectionTitle">Resultados</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Los artículos publicados en revistas españolas tuvieron menor calidad media que los aparecidos en otras revistas europeas o norteamericanas. Los ensayos publicados en España detallaban con menos frecuencia algunos aspectos metodológicos, incluyendo la aprobación del estudio por un comité de ética, la descripción del método de aleatorización o del flujo de pacientes y el enmascaramiento. Dentro de los ensayos publicados en España, los que tenían autor extranjero tuvieron menor calidad media.</p> <span class="elsevierStyleSectionTitle">Conclusión</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">Los ensayos clínicos publicados en España sobre el tratamiento del asma son de menor calidad que los publicados en revistas anglosajonas. Los editores deberían considerar el uso de listas de marcas en el proceso de revisión por pares de los ensayos clínicos para aumentar los estándares de calidad de los trabajos publicados.</p>" ] "en" => array:1 [ "resumen" => "<span class="elsevierStyleSectionTitle">Objectives</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">To evaluate the quality of clinical trials on asthma published in Spanish journals in comparison with those published in European or North American English-language journals.</p> <span class="elsevierStyleSectionTitle">Method</span><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">Clinical trials were identified by searching MEDLINE and the Spanish Medical Index (Índice Médico Español), and by manual searches for trials mentioned in the bibliographies of the previously identified trials. Quality was assessed by the method proposed by Detsky and colleagues in their 1992 article in Journal of Clinical Epidemiology.</p> <span class="elsevierStyleSectionTitle">Results</span><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">The articles published in Spanish journals had lower mean quality scores than those in European or North American English-language journals. Trials published in Spain were less likely to give certain details of methodology, including ethics committee approval, details of randomization or patient enrollment and blinding. Among trials published in Spain, those with non-Spanish authors had lower mean quality scores.</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">Clinical trials published in Spain on asthma treatments are of poorer quality than those published in English-language journals. 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| Year/Month | Html | Total | |
|---|---|---|---|
| 2024 November | 5 | 1 | 6 |
| 2024 October | 33 | 21 | 54 |
| 2024 September | 37 | 16 | 53 |
| 2024 August | 64 | 34 | 98 |
| 2024 July | 32 | 22 | 54 |
| 2024 June | 59 | 29 | 88 |
| 2024 May | 50 | 31 | 81 |
| 2024 April | 33 | 22 | 55 |
| 2024 March | 37 | 32 | 69 |
| 2024 February | 32 | 35 | 67 |
| 2024 January | 0 | 1 | 1 |
| 2023 December | 0 | 5 | 5 |
| 2023 November | 0 | 1 | 1 |
| 2023 October | 0 | 4 | 4 |
| 2023 August | 0 | 4 | 4 |
| 2023 July | 0 | 17 | 17 |
| 2023 June | 0 | 9 | 9 |
| 2023 March | 8 | 4 | 12 |
| 2023 February | 24 | 16 | 40 |
| 2023 January | 26 | 21 | 47 |
| 2022 December | 40 | 26 | 66 |
| 2022 November | 35 | 18 | 53 |
| 2022 October | 30 | 43 | 73 |
| 2022 September | 38 | 31 | 69 |
| 2022 August | 35 | 39 | 74 |
| 2022 July | 25 | 29 | 54 |
| 2022 June | 28 | 31 | 59 |
| 2022 May | 44 | 31 | 75 |
| 2022 April | 21 | 29 | 50 |
| 2022 March | 38 | 32 | 70 |
| 2022 February | 57 | 23 | 80 |
| 2022 January | 51 | 27 | 78 |
| 2021 December | 16 | 36 | 52 |
| 2021 November | 22 | 36 | 58 |
| 2021 October | 18 | 43 | 61 |
| 2021 September | 26 | 34 | 60 |
| 2021 August | 18 | 45 | 63 |
| 2021 July | 17 | 44 | 61 |
| 2021 June | 27 | 47 | 74 |
| 2021 May | 19 | 26 | 45 |
| 2021 April | 33 | 95 | 128 |
| 2021 March | 35 | 18 | 53 |
| 2021 February | 37 | 14 | 51 |
| 2021 January | 32 | 20 | 52 |
| 2020 December | 25 | 23 | 48 |
| 2020 November | 15 | 23 | 38 |
| 2020 October | 11 | 13 | 24 |
| 2020 September | 10 | 12 | 22 |
| 2020 August | 28 | 10 | 38 |
| 2020 July | 29 | 22 | 51 |
| 2020 June | 22 | 19 | 41 |
| 2020 May | 22 | 14 | 36 |
| 2020 April | 29 | 13 | 42 |
| 2020 March | 17 | 20 | 37 |
| 2020 February | 34 | 26 | 60 |
| 2020 January | 44 | 21 | 65 |
| 2019 December | 28 | 25 | 53 |
| 2019 November | 21 | 11 | 32 |
| 2019 October | 22 | 9 | 31 |
| 2019 September | 20 | 12 | 32 |
| 2019 August | 10 | 4 | 14 |
| 2019 July | 21 | 18 | 39 |
| 2019 June | 19 | 16 | 35 |
| 2019 May | 42 | 21 | 63 |
| 2019 April | 23 | 25 | 48 |
| 2019 March | 11 | 8 | 19 |
| 2019 February | 5 | 9 | 14 |
| 2019 January | 10 | 6 | 16 |
| 2018 December | 13 | 20 | 33 |
| 2018 November | 20 | 11 | 31 |
| 2018 October | 39 | 8 | 47 |
| 2018 September | 18 | 7 | 25 |
| 2018 May | 4 | 1 | 5 |
| 2018 April | 9 | 6 | 15 |
| 2018 March | 8 | 6 | 14 |
| 2018 February | 7 | 9 | 16 |
| 2018 January | 4 | 10 | 14 |
| 2017 December | 11 | 14 | 25 |
| 2017 November | 8 | 7 | 15 |
| 2017 October | 11 | 15 | 26 |
| 2017 September | 3 | 2 | 5 |
| 2017 August | 10 | 16 | 26 |
| 2017 July | 6 | 6 | 12 |
| 2017 June | 7 | 10 | 17 |
| 2017 May | 10 | 10 | 20 |
| 2017 April | 7 | 4 | 11 |
| 2017 March | 4 | 5 | 9 |
| 2017 February | 3 | 5 | 8 |
| 2017 January | 2 | 5 | 7 |
| 2016 December | 10 | 7 | 17 |
| 2016 November | 24 | 15 | 39 |
| 2016 October | 27 | 22 | 49 |
| 2016 September | 23 | 13 | 36 |
| 2016 August | 18 | 7 | 25 |
| 2016 July | 16 | 8 | 24 |
| 2016 June | 19 | 6 | 25 |
| 2016 May | 20 | 8 | 28 |
| 2016 April | 16 | 2 | 18 |
| 2016 March | 16 | 4 | 20 |
| 2016 February | 10 | 3 | 13 |
| 2016 January | 33 | 18 | 51 |
| 2015 December | 36 | 14 | 50 |
| 2015 November | 30 | 7 | 37 |
| 2015 October | 108 | 1 | 109 |
| 2015 September | 94 | 0 | 94 |
| 2015 August | 81 | 0 | 81 |
| 2015 July | 80 | 0 | 80 |
| 2015 June | 55 | 0 | 55 |
| 2015 May | 89 | 0 | 89 |
| 2015 April | 51 | 0 | 51 |
| 2015 March | 53 | 0 | 53 |
| 2015 February | 59 | 0 | 59 |
| 2015 January | 61 | 0 | 61 |
| 2014 December | 51 | 0 | 51 |
| 2014 November | 76 | 0 | 76 |
| 2014 October | 94 | 0 | 94 |
| 2014 September | 69 | 0 | 69 |
| 2014 August | 65 | 0 | 65 |
| 2014 July | 57 | 0 | 57 |
| 2014 June | 79 | 0 | 79 |
| 2014 May | 85 | 0 | 85 |
| 2014 April | 79 | 0 | 79 |
| 2014 March | 92 | 0 | 92 |
| 2014 February | 106 | 0 | 106 |
| 2014 January | 66 | 0 | 66 |
| 2013 December | 55 | 0 | 55 |
| 2013 November | 67 | 0 | 67 |
| 2013 October | 87 | 0 | 87 |
| 2013 September | 71 | 0 | 71 |
| 2013 August | 73 | 0 | 73 |
| 2013 July | 85 | 0 | 85 |
| 2013 June | 53 | 0 | 53 |
| 2013 May | 61 | 0 | 61 |
| 2013 April | 44 | 0 | 44 |
| 2013 March | 7 | 0 | 7 |
| 2000 January | 2667 | 0 | 2667 |
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