Evolución de la esclerosis lateral amiotrófica a través de la función pulmonar
Lung function in the course of amyotrophic lateral sclerosis
N. Salord, R.M. Miralda, P. Casan
Corresponding author
pcasan@hsp.santpau.es
Correspondencia: Unidad de Función Pulmonar. Departamento de Neumología.Hospital de la Santa Creu i Sant Pau. Facultad de Medicina. UAB.Avda. Sant Antoni Maria Claret, 167. 08025 Barcelona
Correspondencia: Unidad de Función Pulmonar. Departamento de Neumología.Hospital de la Santa Creu i Sant Pau. Facultad de Medicina. UAB.Avda. Sant Antoni Maria Claret, 167. 08025 Barcelona
Unidad de Función Pulmonar. Departamento de Neumología. Hospital de la Santa Creu i Sant Pau. Facultad de Medicina. UAB. Barcelona
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Salord, R.M. Miralda, P. Casan" "autores" => array:3 [ 0 => array:2 [ "nombre" => "N." "apellidos" => "Salord" ] 1 => array:2 [ "nombre" => "R.M." "apellidos" => "Miralda" ] 2 => array:4 [ "nombre" => "P." "apellidos" => "Casan" "email" => array:1 [ 0 => "pcasan@hsp.santpau.es" ] "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">¿</span>" "identificador" => "cor0005" ] ] ] ] "afiliaciones" => array:1 [ 0 => array:1 [ "entidad" => "Unidad de Función Pulmonar. Departamento de Neumología. Hospital de la Santa Creu i Sant Pau. Facultad de Medicina. UAB. Barcelona" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Correspondencia: Unidad de Función Pulmonar. Departamento de Neumología.Hospital de la Santa Creu i Sant Pau. Facultad de Medicina. UAB.Avda. Sant Antoni Maria Claret, 167. 08025 Barcelona" ] ] ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Lung function in the course of amyotrophic lateral sclerosis" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2001-05-07" "fechaAceptado" => "2001-05-19" "PalabrasClave" => array:2 [ "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec190454" "palabras" => array:3 [ 0 => "Esclerosis lateral amiotrófica" 1 => "Función pulmonar" 2 => "Curva flujo/volumen" ] ] ] "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Keywords" "identificador" => "xpalclavsec190453" "palabras" => array:3 [ 0 => "Amyiotrophic lateral sclerosis" 1 => "Pulmonary function" 2 => "Flow/volume loop" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "es" => array:1 [ "resumen" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Presentamos el caso de un paciente de 26 años de edad diagnosticado de esclerosis lateral amiotrófica (ELA), periódicamente evaluado en su función pulmonar durante los 5,5 años que duró su enfermedad. Se destacan la evolución de la fuerza muscular respiratoria a través de la determinación de las presiones respiratorias máximas y la resistencia muscular vista a partir de la ventilación voluntaria máxima. Asimismo, la forma de la curva flujo/volumen permitió analizar la inestabilidad de la vía aérea superior, que coincidió con la aparición de síntomas bulbares. El estudio de la función pulmonar debe formar parte de la monitorización de las enfermedades neuromusculares</p>" ] "en" => array:1 [ "resumen" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">We report a case of a 26 year old man who was diagnosticated of ALS. This case is a graphic example of the pulmonary function evolution through the flowvolume loop. In the first study the espirometric values were in the normal range. The Static pulmonary pressures were weackledecreased. This was the only sign of respiratory muscle impairement. Its important to study close enough the pulmonary function through the flow/volume loop, maximal respiratory pressures and maximal voluntary Ventilation in order to know the empairment rate, and also to detect intercurrent procedures as bulbar envolvement, that can affect the prognosis of the dissease</p>" ] ] "bibliografia" => array:2 [ "titulo" => "Bibliografía" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:5 [ 0 => array:3 [ "identificador" => "bib0005" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The natural history of amyotrophic lateral sclerosis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "S.P. Ringel" 1 => "J.R. Murphy" 2 => "M.K. 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"referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Forcet vital capacity deterioration in amyotrophic lateral esclerosis has an infleccion point" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "J. Martí-Fàbregas" 1 => "J. Sanchis" 2 => "P. Casan" 3 => "R.M. Miralda" 4 => "E. García-pachón" 5 => "I. Illa" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Eur J Neurol" "fecha" => "1996" "volumen" => "3" "paginaInicial" => "40" "paginaFinal" => "43" ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib0020" "etiqueta" => "4." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Maximal respiratory pressures in generalized neuromuscular disease" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "L.F. Black" 1 => "R.E. Hyatt" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1164/arrd.1971.103.5.641" "Revista" => array:6 [ "tituloSerie" => "Am Rev Respir Dis" "fecha" => "1971" "volumen" => "103" "paginaInicial" => "641" "paginaFinal" => "650" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/5579907" "web" => "Medline" ] ] ] ] ] ] ] ] 4 => array:3 [ "identificador" => "bib0025" "etiqueta" => "5." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Clinical significance of upper airway dysfunction in motor neurone disease" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "E. García-pachón" 1 => "J. Martí" 2 => "M. Mayos" 3 => "P. Casan" 4 => "J. 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