Utilización de Internet en un estudio multicéntrico sobre EPOC en atención primaria. Fase piloto del estudio EFEMAP
Use of the Internet in a multicenter study of chronic obstructive pulmonary disease in primary care.Pilot phase of the EFEMAP study
M. Miravitllesa,
, C. Llorb, K. Naberanc, J.M. Cotsb, en representación del estudio Efemap *
Corresponding author
marcm@separ.es
Correspondencia: Servicio de Neumología. Institut Clínic de Pneumologia i Cirurgia Toràcica.Hospital Clínic i Provincial.Villarroel, 170, UVIR, esc. 2, planta 3. 08036 Barcelona
Correspondencia: Servicio de Neumología. Institut Clínic de Pneumologia i Cirurgia Toràcica.Hospital Clínic i Provincial.Villarroel, 170, UVIR, esc. 2, planta 3. 08036 Barcelona
a Servicio de Neumología. Institut Clínic de Pneumologia i Cirurgia Toràcica (Idibaps). Hospital Clínic i Provincial. Barcelona
b Médicos de familia. Grupo de Enfermedades Infecciosas de la Sociedad Catalana de Medicina Familiar
c Médico de familia. Grupo de Neumología de la Sociedad Catalana de Medicina Familiar
Read
8293
Timeswas read the article
1830
Total PDF
6463
Total HTML
Share statistics
array:23 [ "pii" => "S0300289602752563" "issn" => "03002896" "doi" => "10.1016/S0300-2896(02)75256-3" "estado" => "S300" "fechaPublicacion" => "2002-09-01" "aid" => "75256" "copyright" => "Sociedad Española de Neumología y Cirugía Torácica" "copyrightAnyo" => "2002" "documento" => "article" "crossmark" => 0 "subdocumento" => "fla" "cita" => "Arch Bronconeumol. 2002;38:427-30" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 5933 "formatos" => array:3 [ "EPUB" => 56 "HTML" => 5266 "PDF" => 611 ] ] "itemSiguiente" => array:18 [ "pii" => "S0300289602752575" "issn" => "03002896" "doi" => "10.1016/S0300-2896(02)75257-5" "estado" => "S300" "fechaPublicacion" => "2002-09-01" "aid" => "75257" "copyright" => "Sociedad Española de Neumología y Cirugía Torácica" "documento" => "article" "crossmark" => 0 "subdocumento" => "fla" "cita" => "Arch Bronconeumol. 2002;38:431-5" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 8026 "formatos" => array:3 [ "EPUB" => 67 "HTML" => 6921 "PDF" => 1038 ] ] "es" => array:7 [ "idiomaDefecto" => true "titulo" => "La necesidad de objetivar en medicina y sus tribulaciones" "tienePdf" => "es" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "431" "paginaFinal" => "435" ] ] "contienePdf" => array:1 [ "es" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "J. Sanchis Aldás" "autores" => array:1 [ 0 => array:2 [ "nombre" => "J." "apellidos" => "Sanchis Aldás" ] ] ] ] ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289602752575?idApp=UINPBA00003Z" "url" => "/03002896/0000003800000009/v1_201307081507/S0300289602752575/v1_201307081507/es/main.assets" ] "itemAnterior" => array:18 [ "pii" => "S0300289602752551" "issn" => "03002896" "doi" => "10.1016/S0300-2896(02)75255-1" "estado" => "S300" "fechaPublicacion" => "2002-09-01" "aid" => "75255" "copyright" => "Sociedad Española de Neumología y Cirugía Torácica" "documento" => "article" "crossmark" => 0 "subdocumento" => "fla" "cita" => "Arch Bronconeumol. 2002;38:421-6" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 10051 "formatos" => array:3 [ "EPUB" => 64 "HTML" => 9349 "PDF" => 638 ] ] "es" => array:10 [ "idiomaDefecto" => true "titulo" => "Nuestra experiencia en el tratamiento de las hiperhidrosis de los miembros superiores mediante videotoracoscopia: análisis tras las primeras 100 intervenciones" "tienePdf" => "es" "tieneTextoCompleto" => 0 "tieneResumen" => array:2 [ 0 => "es" 1 => "en" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "421" "paginaFinal" => "426" ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Our experience in the treatment of hyperhidrosis of the upper limbs by video-assisted thoracoscopy:an analysis of our first 100 procedures" ] ] "contieneResumen" => array:2 [ "es" => true "en" => true ] "contienePdf" => array:1 [ "es" => true ] "autores" => array:2 [ 0 => array:2 [ "autoresLista" => "R. Guijarro Jorge, A. Arnau Obrer, A. Fernández Centeno, F. Regueiro Mira, A. Pérez Alonso, M. Cañizares Carretero, A. Cantó Armengod" "autores" => array:7 [ 0 => array:2 [ "nombre" => "R." "apellidos" => "Guijarro Jorge" ] 1 => array:2 [ "nombre" => "A." "apellidos" => "Arnau Obrer" ] 2 => array:2 [ "nombre" => "A." "apellidos" => "Fernández Centeno" ] 3 => array:2 [ "nombre" => "F." "apellidos" => "Regueiro Mira" ] 4 => array:2 [ "nombre" => "A." "apellidos" => "Pérez Alonso" ] 5 => array:2 [ "nombre" => "M." "apellidos" => "Cañizares Carretero" ] 6 => array:2 [ "nombre" => "A." "apellidos" => "Cantó Armengod" ] ] ] 1 => array:2 [ "autoresLista" => "M. Granell Gil" "autores" => array:1 [ 0 => array:2 [ "nombre" => "M." "apellidos" => "Granell Gil" ] ] ] ] ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289602752551?idApp=UINPBA00003Z" "url" => "/03002896/0000003800000009/v1_201307081507/S0300289602752551/v1_201307081507/es/main.assets" ] "es" => array:15 [ "idiomaDefecto" => true "titulo" => "Utilización de Internet en un estudio multicéntrico sobre EPOC en atención primaria. Fase piloto del estudio EFEMAP" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "427" "paginaFinal" => "430" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "M. Miravitlles, C. Llor, K. Naberan, J.M. Cots" "autores" => array:5 [ 0 => array:4 [ "nombre" => "M." "apellidos" => "Miravitlles" "email" => array:1 [ 0 => "marcm@separ.es" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">¿</span>" "identificador" => "cor0005" ] ] ] 1 => array:3 [ "nombre" => "C." "apellidos" => "Llor" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] ] 2 => array:3 [ "nombre" => "K." "apellidos" => "Naberan" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">c</span>" "identificador" => "aff0015" ] ] ] 3 => array:3 [ "nombre" => "J.M." "apellidos" => "Cots" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] ] 4 => array:2 [ "colaborador" => "en representación del estudio Efemap" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "fn0005" ] ] ] ] "afiliaciones" => array:3 [ 0 => array:3 [ "entidad" => "Servicio de Neumología. Institut Clínic de Pneumologia i Cirurgia Toràcica (Idibaps). Hospital Clínic i Provincial. Barcelona" "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "Médicos de familia. Grupo de Enfermedades Infecciosas de la Sociedad Catalana de Medicina Familiar" "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] 2 => array:3 [ "entidad" => "Médico de familia. Grupo de Neumología de la Sociedad Catalana de Medicina Familiar" "etiqueta" => "<span class="elsevierStyleSup">c</span>" "identificador" => "aff0015" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Correspondencia: Servicio de Neumología. Institut Clínic de Pneumologia i Cirurgia Toràcica.Hospital Clínic i Provincial.Villarroel, 170, UVIR, esc. 2, planta 3. 08036 Barcelona" ] ] ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Use of the Internet in a multicenter study of chronic obstructive pulmonary disease in primary care.Pilot phase of the EFEMAP study" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2002-01-24" "fechaAceptado" => "2002-05-14" "PalabrasClave" => array:2 [ "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec190457" "palabras" => array:5 [ 0 => "Internet" 1 => "EPOC" 2 => "Atención primaria" 3 => "Agudizacio-nes" 4 => "Tratamiento" ] ] ] "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Keywords" "identificador" => "xpalclavsec190458" "palabras" => array:5 [ 0 => "Internet" 1 => "COPD" 2 => "Primary care" 3 => "Exacerbations" 4 => "Tre-atment" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "es" => array:1 [ "resumen" => "<span class="elsevierStyleSectionTitle">Objetivos</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Conocer la viabilidad de la recogida y transmisión de datos clínicos por Internet en un estudio multicén-trico en atención primaria</p> <span class="elsevierStyleSectionTitle">Pacientes Y Métodos</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Estudio observacional, multicéntrico sobre una población de pacientes con enfermedad pul-monar obstructiva crónica agudizada. Todos los datos se recogieron en un formulario electrónico diseñado específicamente, que se encontraba incorporado en un ordenador portátil de bolsillo. La transmisión de los datos se efectuó on line a una base de datos unificada mediante conexión telefónica por módem</p> <span class="elsevierStyleSectionTitle">Resultados</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Participaron en esta fase piloto 39 investigadores, que incluyeron a 324 pacientes durante 3 meses. Se generaron 37 consultas telefónicas, la mayoría (54%) referida al funcionamiento del cuestionario electrónico, que se solucionó en un promedio de 5,44 min. La metodología utilizada no presentó ningún problema técnico de importancia ni se detectó ninguna pérdida de información</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">La utilización de Internet en estudios multicéntricos en atención primaria es posible. Este sistema debe extenderse en un futuro, pues permite una rapidez superior en la entrada de datos y elimina la necesidad de gra-bación de los mismos tras finalizar el estudio</p>" ] "en" => array:1 [ "resumen" => "<span class="elsevierStyleSectionTitle">Objective</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">To determine the reliability of clinical data collection and transmission by Internet in a multicenter pri-mary care study</p> <span class="elsevierStyleSectionTitle">Patients And Methods</span><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">Multicenter, observational study of a population of patients with exacerbated chronic obstructive pulmonary disease (COPD). All data were gathered in a specifically designed digital program on a palmheld pocket computer. Information was transmitted on-line by modem to a central database</p> <span class="elsevierStyleSectionTitle">Results</span><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">Thirty-nine researchers participated in this pilot phase. Over three months 324 patients were treated. Thirty-seven telephone consultations were generated, most (54%) in reference to how the digitized questionnaire worked. Questions were solved in a mean 5.44 minutes. No important technical problems occurred and no information was lost</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">The use of the Internet to transfer data for multicentric studies in primary care is possible. This system should be more widely used in the future, as it allows faster data collection and eliminates the need to input data at the end of the study</p>" ] ] "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "*" "nota" => "<p class="elsevierStyleNotepara">El estudio EFEMAP ha sido financiado por Química Farmacéutica Bayer, S.A. La lista de investigadores participantes se presenta en el anexo</p>" ] ] "bibliografia" => array:2 [ "titulo" => "Bibliografía" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:13 [ 0 => array:3 [ "identificador" => "bib0005" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Geographical variations in prevalence and underdiagnosis of COPD. Results of the IBERPOC multicentre epidemiological study" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "V. Sobradillo" 1 => "M. Miravitlles" 2 => "R. Gabriel" 3 => "C.A. Jiménez-ruiz" 4 => "C. Villasante" 5 => "J.F. Masa" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Chest" "fecha" => "2000" "volumen" => "118" "paginaInicial" => "981" "paginaFinal" => "989" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11035667" "web" => "Medline" ] ] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib0010" "etiqueta" => "2." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Treatment of chronic obstructive pulmonary disease and its exacerbations in general practice" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:7 [ 0 => "M. Miravitlles" 1 => "C. Mayordomo" 2 => "M. Artés" 3 => "L. Sánchez-Agudo" 4 => "F. Nicolau" 5 => "J.L. Segú" 6 => "Group on behalf of the EOLO" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Respir Med" "fecha" => "1999" "volumen" => "93" "paginaInicial" => "173" "paginaFinal" => "179" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10464874" "web" => "Medline" ] ] ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib0015" "etiqueta" => "3." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Murio C (Grupo DAFNE). Estudio farmacoeconómico del tratamiento antibiótico de las agudizaciones de la bronquitis crónica en atención primaria" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "M. Miravitlles" 1 => "J.l. Segú" 2 => "T. Guerrero" 3 => "R. Gisbert" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Aten Primaria" "fecha" => "2000" "volumen" => "25" "paginaInicial" => "153" "paginaFinal" => "159" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10730438" "web" => "Medline" ] ] ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib0020" "etiqueta" => "4." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Pharmacoeconomic evaluation of acute exacerbations of chronic bronchitis and COPD" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "M. Miravitlles" 1 => "C. Murio" 2 => "T. Guerrero" 3 => "R. Gisbert" 4 => "group on behalf of the DAFNE study" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Chest" "fecha" => "2002" "volumen" => "121" "paginaInicial" => "1449" "paginaFinal" => "1455" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12006427" "web" => "Medline" ] ] ] ] ] ] ] ] 4 => array:3 [ "identificador" => "bib0025" "etiqueta" => "5." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Guía clínica para el diagnóstico y el tratamiento de la enfermedad pulmonar obstructiva crónica" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "J.A. Barberà" 1 => "G. Peces-Barba" 2 => "A.G.N. Agustí" 3 => "J.L. Izquierdo" 4 => "E. Monsó" 5 => "T. Montemayor" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Arch Bronconeumol" "fecha" => "2001" "volumen" => "37" "paginaInicial" => "297" "paginaFinal" => "316" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11412529" "web" => "Medline" ] ] ] ] ] ] ] ] 5 => array:3 [ "identificador" => "bib0030" "etiqueta" => "6." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Antibiotic therapy in exacerbations of chronic obstructive pulmonary disease" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "N.R. Anthonisen" 1 => "J. Manfreda" 2 => "P.W. Warren" 3 => "E.S. Hershfield" 4 => "G.K. Harding" 5 => "N.A. Nelson" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Ann Intern Med" "fecha" => "1987" "volumen" => "106" "paginaInicial" => "196" "paginaFinal" => "204" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3492164" "web" => "Medline" ] ] ] ] ] ] ] ] 6 => array:3 [ "identificador" => "bib0035" "etiqueta" => "7." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Recomendaciones para la atención al paciente con enfermedad pulmonar obstructiva crónica" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "J.L. Álvarez-Sala" 1 => "E. Cimas" 2 => "J.F. Masa" 3 => "M. Miravitlles" 4 => "J. Molina" 5 => "K. Naberan" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Arch Bronconeumol" "fecha" => "2001" "volumen" => "37" "paginaInicial" => "269" "paginaFinal" => "278" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11481057" "web" => "Medline" ] ] ] ] ] ] ] ] 7 => array:3 [ "identificador" => "bib0040" "etiqueta" => "8." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Uso de antimicrobianos en la exacerbación de la enfermedad pulmonar obstructiva crónica" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "F. Álvarez" 1 => "E. Bouza" 2 => "J.A. García-rodríguez" 3 => "M.A. Mayer" 4 => "J. Mensa" 5 => "E. Monsó" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Rev Esp Quimioterap" "fecha" => "2001" "volumen" => "14" "paginaInicial" => "87" "paginaFinal" => "96" ] ] ] ] ] ] 8 => array:3 [ "identificador" => "bib0045" "etiqueta" => "9." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Tratamiento de la bronquitis crónica y la EPOC en atención primaria" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "M. Miravitlles" 1 => "C. Murio" 2 => "T. Guerrero" 3 => "J.L. Segú" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Arch Bronconeumol" "fecha" => "1999" "volumen" => "35" "paginaInicial" => "173" "paginaFinal" => "178" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10330538" "web" => "Medline" ] ] ] ] ] ] ] ] 9 => array:3 [ "identificador" => "bib0050" "etiqueta" => "10." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The efficacy of moxifloxacin in acute exacerbations of chronic bronchitis; a Spanish physician and patient experience" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "M. Miravitlles" 1 => "F. Ros" 2 => "A. Cobos" 3 => "R. Kubin" 4 => "G. Tillotson" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Int J Clin Pract" "fecha" => "2001" "volumen" => "55" "paginaInicial" => "437" "paginaFinal" => "441" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11594251" "web" => "Medline" ] ] ] ] ] ] ] ] 10 => array:3 [ "identificador" => "bib0055" "etiqueta" => "11." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Factors associated with relapse after ambulatory treatment of acute exacerbations of chronic bronchitis. A prospective multicenter study in the community" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "M. Miravitlles" 1 => "C. Murio" 2 => "T. Guerrero" 3 => "Group on behalf of the DAFNE Study" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Eur Respir J" "fecha" => "2001" "volumen" => "17" "paginaInicial" => "928" "paginaFinal" => "933" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11488328" "web" => "Medline" ] ] ] ] ] ] ] ] 11 => array:3 [ "identificador" => "bib0060" "etiqueta" => "12." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Prospective study of aetiology and outcome of adult lower respiratory tract infections in the community" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "J.T. MacFarlane" 1 => "A. Colville" 2 => "A. Guion" 3 => "R.M. MacFarlane" 4 => "D.H. Rose" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Lancet" "fecha" => "1993" "volumen" => "341" "paginaInicial" => "511" "paginaFinal" => "514" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8094769" "web" => "Medline" ] ] ] ] ] ] ] ] 12 => array:3 [ "identificador" => "bib0065" "etiqueta" => "13." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Antibiotics are associated with lower relapse rates in outpatients with acute exacerbations of COPD" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "S.G. Adams" 1 => "J. Melo" 2 => "M. Luther" 3 => "A. Anzueto" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Chest" "fecha" => "2000" "volumen" => "117" "paginaInicial" => "1345" "paginaFinal" => "1352" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10807821" "web" => "Medline" ] ] ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "es" "url" => "/03002896/0000003800000009/v1_201307081507/S0300289602752563/v1_201307081507/es/main.assets" "Apartado" => array:4 [ "identificador" => "9277" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Originales" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/03002896/0000003800000009/v1_201307081507/S0300289602752563/v1_201307081507/es/main.pdf?idApp=UINPBA00003Z&text.app=https://archbronconeumol.org/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289602752563?idApp=UINPBA00003Z" ]
| Year/Month | Html | Total | |
|---|---|---|---|
| 2024 November | 8 | 2 | 10 |
| 2024 October | 29 | 15 | 44 |
| 2024 September | 39 | 18 | 57 |
| 2024 August | 50 | 27 | 77 |
| 2024 July | 33 | 21 | 54 |
| 2024 June | 42 | 18 | 60 |
| 2024 May | 45 | 27 | 72 |
| 2024 April | 27 | 21 | 48 |
| 2024 March | 26 | 28 | 54 |
| 2024 February | 25 | 36 | 61 |
| 2023 December | 0 | 3 | 3 |
| 2023 November | 0 | 2 | 2 |
| 2023 October | 0 | 2 | 2 |
| 2023 September | 0 | 3 | 3 |
| 2023 August | 0 | 6 | 6 |
| 2023 July | 0 | 6 | 6 |
| 2023 June | 0 | 18 | 18 |
| 2023 May | 0 | 1 | 1 |
| 2023 March | 3 | 3 | 6 |
| 2023 February | 28 | 19 | 47 |
| 2023 January | 19 | 30 | 49 |
| 2022 December | 34 | 30 | 64 |
| 2022 November | 29 | 16 | 45 |
| 2022 October | 19 | 33 | 52 |
| 2022 September | 28 | 23 | 51 |
| 2022 August | 28 | 40 | 68 |
| 2022 July | 17 | 38 | 55 |
| 2022 June | 31 | 31 | 62 |
| 2022 May | 22 | 23 | 45 |
| 2022 April | 34 | 26 | 60 |
| 2022 March | 36 | 33 | 69 |
| 2022 February | 23 | 24 | 47 |
| 2022 January | 23 | 23 | 46 |
| 2021 December | 20 | 40 | 60 |
| 2021 November | 16 | 45 | 61 |
| 2021 October | 28 | 38 | 66 |
| 2021 September | 19 | 40 | 59 |
| 2021 August | 10 | 27 | 37 |
| 2021 July | 19 | 13 | 32 |
| 2021 June | 30 | 38 | 68 |
| 2021 May | 11 | 26 | 37 |
| 2021 April | 25 | 69 | 94 |
| 2021 March | 44 | 39 | 83 |
| 2021 February | 44 | 14 | 58 |
| 2021 January | 27 | 22 | 49 |
| 2020 December | 27 | 13 | 40 |
| 2020 November | 18 | 25 | 43 |
| 2020 October | 18 | 14 | 32 |
| 2020 September | 18 | 11 | 29 |
| 2020 August | 22 | 11 | 33 |
| 2020 July | 25 | 20 | 45 |
| 2020 June | 13 | 6 | 19 |
| 2020 May | 11 | 10 | 21 |
| 2020 April | 37 | 26 | 63 |
| 2020 March | 14 | 19 | 33 |
| 2020 February | 18 | 17 | 35 |
| 2020 January | 34 | 22 | 56 |
| 2019 December | 19 | 20 | 39 |
| 2019 November | 8 | 14 | 22 |
| 2019 October | 6 | 6 | 12 |
| 2019 September | 11 | 17 | 28 |
| 2019 August | 7 | 4 | 11 |
| 2019 July | 11 | 31 | 42 |
| 2019 June | 14 | 23 | 37 |
| 2019 May | 15 | 40 | 55 |
| 2019 April | 24 | 49 | 73 |
| 2019 March | 10 | 21 | 31 |
| 2019 February | 8 | 11 | 19 |
| 2019 January | 6 | 12 | 18 |
| 2018 December | 8 | 12 | 20 |
| 2018 November | 18 | 12 | 30 |
| 2018 October | 18 | 16 | 34 |
| 2018 September | 14 | 8 | 22 |
| 2018 May | 6 | 1 | 7 |
| 2018 April | 5 | 5 | 10 |
| 2018 March | 5 | 9 | 14 |
| 2018 February | 7 | 8 | 15 |
| 2018 January | 5 | 6 | 11 |
| 2017 December | 8 | 15 | 23 |
| 2017 November | 7 | 8 | 15 |
| 2017 October | 11 | 10 | 21 |
| 2017 September | 6 | 2 | 8 |
| 2017 August | 7 | 20 | 27 |
| 2017 July | 12 | 18 | 30 |
| 2017 June | 12 | 9 | 21 |
| 2017 May | 8 | 14 | 22 |
| 2017 April | 10 | 6 | 16 |
| 2017 March | 8 | 10 | 18 |
| 2017 February | 4 | 3 | 7 |
| 2017 January | 5 | 7 | 12 |
| 2016 December | 15 | 13 | 28 |
| 2016 November | 23 | 13 | 36 |
| 2016 October | 20 | 15 | 35 |
| 2016 September | 23 | 14 | 37 |
| 2016 August | 28 | 15 | 43 |
| 2016 July | 19 | 11 | 30 |
| 2016 June | 19 | 11 | 30 |
| 2016 May | 15 | 6 | 21 |
| 2016 April | 10 | 0 | 10 |
| 2016 March | 7 | 2 | 9 |
| 2016 February | 14 | 1 | 15 |
| 2016 January | 30 | 15 | 45 |
| 2015 December | 19 | 9 | 28 |
| 2015 November | 23 | 5 | 28 |
| 2015 October | 79 | 2 | 81 |
| 2015 September | 76 | 0 | 76 |
| 2015 August | 74 | 0 | 74 |
| 2015 July | 58 | 0 | 58 |
| 2015 June | 75 | 0 | 75 |
| 2015 May | 67 | 0 | 67 |
| 2015 April | 53 | 0 | 53 |
| 2015 March | 57 | 0 | 57 |
| 2015 February | 47 | 0 | 47 |
| 2015 January | 49 | 0 | 49 |
| 2014 December | 56 | 0 | 56 |
| 2014 November | 60 | 0 | 60 |
| 2014 October | 73 | 0 | 73 |
| 2014 September | 71 | 0 | 71 |
| 2014 August | 63 | 0 | 63 |
| 2014 July | 44 | 0 | 44 |
| 2014 June | 46 | 0 | 46 |
| 2014 May | 61 | 0 | 61 |
| 2014 April | 49 | 0 | 49 |
| 2014 March | 48 | 0 | 48 |
| 2014 February | 45 | 0 | 45 |
| 2014 January | 39 | 0 | 39 |
| 2013 December | 40 | 0 | 40 |
| 2013 November | 50 | 0 | 50 |
| 2013 October | 43 | 0 | 43 |
| 2013 September | 45 | 0 | 45 |
| 2013 August | 64 | 0 | 64 |
| 2013 July | 71 | 0 | 71 |
| 2013 June | 44 | 0 | 44 |
| 2013 May | 32 | 0 | 32 |
| 2013 April | 28 | 0 | 28 |
| 2013 March | 8 | 0 | 8 |
| 2000 January | 2914 | 0 | 2914 |
Show all
