array:23 [
  "pii" => "S0300289615321931"
  "issn" => "03002896"
  "doi" => "10.1016/S0300-2896(15)32193-1"
  "estado" => "S300"
  "fechaPublicacion" => "1985-03-01"
  "aid" => "72263"
  "copyright" => "Sociedad Española de Neumología y Cirugía Torácica"
  "copyrightAnyo" => "1985"
  "documento" => "article"
  "crossmark" => 0
  "subdocumento" => "fla"
  "cita" => "Arch Bronconeumol. 1985;21:55-7"
  "abierto" => array:3 [
    "ES" => true
    "ES2" => true
    "LATM" => true
  ]
  "gratuito" => true
  "lecturas" => array:2 [
    "total" => 1394
    "formatos" => array:3 [
      "EPUB" => 48
      "HTML" => 804
      "PDF" => 542
    ]
  ]
  "itemSiguiente" => array:18 [
    "pii" => "S0300289615321943"
    "issn" => "03002896"
    "doi" => "10.1016/S0300-2896(15)32194-3"
    "estado" => "S300"
    "fechaPublicacion" => "1985-03-01"
    "aid" => "72264"
    "copyright" => "Sociedad Española de Neumología y Cirugía Torácica"
    "documento" => "article"
    "crossmark" => 0
    "subdocumento" => "fla"
    "cita" => "Arch Bronconeumol. 1985;21:58-62"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 1110
      "formatos" => array:3 [
        "EPUB" => 52
        "HTML" => 614
        "PDF" => 444
      ]
    ]
    "es" => array:10 [
      "idiomaDefecto" => true
      "titulo" => "Alteraciones radiograficas en niños con asma agudizado"
      "tienePdf" => "es"
      "tieneTextoCompleto" => 0
      "tieneResumen" => array:2 [
        0 => "es"
        1 => "en"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "58"
          "paginaFinal" => "62"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "en" => array:1 [
          "titulo" => "Radiographic alterations in children with acute asthma"
        ]
      ]
      "contieneResumen" => array:2 [
        "es" => true
        "en" => true
      ]
      "contienePdf" => array:1 [
        "es" => true
      ]
      "autores" => array:2 [
        0 => array:2 [
          "autoresLista" => "A. Roman, P. Romero, E. Fernandez, R.M. Bandres, J.L. Del Campo, G.F. Rego"
          "autores" => array:6 [
            0 => array:2 [
              "nombre" => "A."
              "apellidos" => "Roman"
            ]
            1 => array:2 [
              "nombre" => "P."
              "apellidos" => "Romero"
            ]
            2 => array:2 [
              "nombre" => "E."
              "apellidos" => "Fernandez"
            ]
            3 => array:2 [
              "nombre" => "R.M."
              "apellidos" => "Bandres"
            ]
            4 => array:2 [
              "nombre" => "J.L."
              "apellidos" => "Del Campo"
            ]
            5 => array:2 [
              "nombre" => "G.F."
              "apellidos" => "Rego"
            ]
          ]
        ]
        1 => array:2 [
          "autoresLista" => "A. Diaz"
          "autores" => array:1 [
            0 => array:2 [
              "nombre" => "A."
              "apellidos" => "Diaz"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "es"
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289615321943?idApp=UINPBA00003Z"
    "url" => "/03002896/0000002100000002/v1_201509151142/S0300289615321943/v1_201509151142/es/main.assets"
  ]
  "itemAnterior" => array:18 [
    "pii" => "S030028961532192X"
    "issn" => "03002896"
    "doi" => "10.1016/S0300-2896(15)32192-X"
    "estado" => "S300"
    "fechaPublicacion" => "1985-03-01"
    "aid" => "72262"
    "copyright" => "Sociedad Española de Neumología y Cirugía Torácica"
    "documento" => "article"
    "crossmark" => 0
    "subdocumento" => "fla"
    "cita" => "Arch Bronconeumol. 1985;21:51-4"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 1177
      "formatos" => array:3 [
        "EPUB" => 57
        "HTML" => 603
        "PDF" => 517
      ]
    ]
    "es" => array:10 [
      "idiomaDefecto" => true
      "titulo" => "Proteinosis alveolar: a proposito de tres observaciones"
      "tienePdf" => "es"
      "tieneTextoCompleto" => 0
      "tieneResumen" => array:2 [
        0 => "es"
        1 => "en"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "51"
          "paginaFinal" => "54"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "en" => array:1 [
          "titulo" => "Pulmonary alveolar proteinosis: three cases report"
        ]
      ]
      "contieneResumen" => array:2 [
        "es" => true
        "en" => true
      ]
      "contienePdf" => array:1 [
        "es" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "J. Fernandez-Bujarrabal Villoslada, A. Garcia De Cabo, J.A. Hermida Gutierrez, A. Nevado Caballero, L. Sanchez Agudo, F.J. Guerra Sanz"
          "autores" => array:6 [
            0 => array:2 [
              "nombre" => "J."
              "apellidos" => "Fernandez-Bujarrabal Villoslada"
            ]
            1 => array:2 [
              "nombre" => "A."
              "apellidos" => "Garcia De Cabo"
            ]
            2 => array:2 [
              "nombre" => "J.A."
              "apellidos" => "Hermida Gutierrez"
            ]
            3 => array:2 [
              "nombre" => "A."
              "apellidos" => "Nevado Caballero"
            ]
            4 => array:2 [
              "nombre" => "L."
              "apellidos" => "Sanchez Agudo"
            ]
            5 => array:2 [
              "nombre" => "F.J."
              "apellidos" => "Guerra Sanz"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "es"
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S030028961532192X?idApp=UINPBA00003Z"
    "url" => "/03002896/0000002100000002/v1_201509151142/S030028961532192X/v1_201509151142/es/main.assets"
  ]
  "es" => array:13 [
    "idiomaDefecto" => true
    "titulo" => "Escrofulas: tratamiento controlado con un esquema de nueve meses"
    "tieneTextoCompleto" => 0
    "paginas" => array:1 [
      0 => array:2 [
        "paginaInicial" => "55"
        "paginaFinal" => "57"
      ]
    ]
    "autores" => array:1 [
      0 => array:3 [
        "autoresLista" => "E. Fite, R. Vidal, J. Ruiz-Manzano, L. Juanmiquel, J. Morera"
        "autores" => array:5 [
          0 => array:2 [
            "nombre" => "E."
            "apellidos" => "Fite"
          ]
          1 => array:2 [
            "nombre" => "R."
            "apellidos" => "Vidal"
          ]
          2 => array:2 [
            "nombre" => "J."
            "apellidos" => "Ruiz-Manzano"
          ]
          3 => array:2 [
            "nombre" => "L."
            "apellidos" => "Juanmiquel"
          ]
          4 => array:2 [
            "nombre" => "J."
            "apellidos" => "Morera"
          ]
        ]
        "afiliaciones" => array:1 [
          0 => array:2 [
            "entidad" => "Secció de Pneumologia. Ciutat Sanitària de la Vall d’Hebron. Barcelona"
            "identificador" => "aff0005"
          ]
        ]
      ]
    ]
    "titulosAlternativos" => array:1 [
      "en" => array:1 [
        "titulo" => "Scrofula: a nine-month controlled therapeutic trial"
      ]
    ]
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "fechaRecibido" => "1984-06-04"
    "fechaAceptado" => "1984-10-26"
    "tieneResumen" => true
    "resumen" => array:2 [
      "es" => array:1 [
        "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Aportamos los resultados preliminares del tratamiento en 33 pacientes con adenitis tuberculosa perif&#233;rica&#44; con un esquema de nueve meses que inclu&#237;a&#58; rifampicina 600<span class="elsevierStyleHsp" style=""></span>mg&#47;d&#237;a e isoniacida 300<span class="elsevierStyleHsp" style=""></span>mg&#47;d&#237;a&#44; m&#225;s etambutol 25<span class="elsevierStyleHsp" style=""></span>mg&#47;kg&#47;dia los dos primeros meses&#46;</p><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Durante el tratamiento&#44; a partir del tercer mes&#44; dos casos precisaron drenaje quir&#250;rgico&#44; uno desbridamiento de un absceso y otro ex&#233;resis quir&#250;rgica&#46; Al final del tratamiento los otros 27 casos hab&#237;an evolucionado satisfactoriamente y no precisaron cirug&#237;a&#46; No se presentaron complicaciones cl&#237;nicas secundarias a la quimioterapia&#46;</p><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">De los 33 pacientes&#44; en 24 ha transcurrido m&#225;s de un a&#241;o desde que finalizaron el tratamiento&#46; Uno de ellos no ha acudido a control&#44; los 23 restantes se presentaron al a&#241;o de terminar la terap&#233;utica y en ninguno de ellos ha habido recidivas&#46;</p><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">Con estos resultados pensamos que&#44; al igual que en la tuberculosis pulmonar&#44; la adenitis tuberculosa perif&#233;rica puede ser tratada con pr&#225;cticamente el 100&#37; de curaciones con esquemas de nueve meses que incluyan rifampicina e isoniacida&#46;</p></span>"
      ]
      "en" => array:1 [
        "resumen" => "<span id="abst0010" class="elsevierStyleSection elsevierViewall"><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">The authors present the preliminary results of a ninemonth treatment for peripheral tuberculous adenitis&#46;</p><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">The trial included 33 patients who were given rifampicin at doses of 600<span class="elsevierStyleHsp" style=""></span>mg&#47;day and isoniazid at doses of 300<span class="elsevierStyleHsp" style=""></span>mg&#47;day plus 25<span class="elsevierStyleHsp" style=""></span>mg&#47;Kg&#47;day ethambutol for the first two months&#46;</p><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">After the third month of treatment two patients required surgical drainage and debridement of an abscess and further exeresis&#46; The other 27 patients had a satisfactory response to the therapy and did not require surgical treatment&#46; No side effects to the chemotherapy were seen in any of the patients&#46;</p><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">Of the 24 patients out of the total 33 in the group&#44; for whom more than one year has elapsed since finishing therapy&#44; 23 were seen exactly one year later while one was lost to followup&#59; there were no relapses&#46;</p><p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">These results strongly suggest that peripherical tuberculous adenitis may be treated succesfully &#8212;as in pulmonary tuberculosis&#8212; with a nine month schedule including rifampicin and isoniazids which elicit a cure rate of approximately 100&#37;&#46;</p></span>"
      ]
    ]
    "bibliografia" => array:2 [
      "titulo" => "Bibliografia"
      "seccion" => array:1 [
        0 => array:2 [
          "identificador" => "bibs0005"
          "bibliografiaReferencia" => array:24 [
            0 => array:3 [
              "identificador" => "bib0005"
              "etiqueta" => "1&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Superficial glandular tuberculosis&#46; Treatment with chemotherapy"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "G&#46;S&#46; Kilpatrick"
                            1 => "A&#46;C&#46; Douglas"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Brit Med J"
                        "fecha" => "1957"
                        "volumen" => "2"
                        "paginaInicial" => "612"
                        "paginaFinal" => "614"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/497740"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib0010"
              "etiqueta" => "2&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The current status and treatment of lymphatic tuberculosis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "J&#46;M&#46; Schless"
                            1 => "J&#46;A&#46; Wier"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Am Rev Tuberculosis"
                        "fecha" => "1957"
                        "volumen" => "76"
                        "paginaInicial" => "811"
                        "paginaFinal" => "831"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib0015"
              "etiqueta" => "3&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The treatment of tuberculous lymphadenitis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "P&#46;M&#46;S&#46; Gillam"
                            1 => "J&#46;P&#46; Knowles"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Tubercle"
                        "fecha" => "1963"
                        "volumen" => "44"
                        "paginaInicial" => "112"
                        "paginaFinal" => "118"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/13947883"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib0020"
              "etiqueta" => "4&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Peripheral tuberculous lymphadenitis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "H&#46;S&#46; Fraser"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Brit J Dis Chest"
                        "fecha" => "1965"
                        "volumen" => "59"
                        "paginaInicial" => "164"
                        "paginaFinal" => "172"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/14339014"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bib0025"
              "etiqueta" => "5&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Tuberculous Lymphadenitis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "P&#46;B&#46; Iles"
                            1 => "P&#46;A&#46; Emerson"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Brit Med J"
                        "fecha" => "1974"
                        "volumen" => "1"
                        "paginaInicial" => "143"
                        "paginaFinal" => "145"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1247747"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            5 => array:3 [
              "identificador" => "bib0030"
              "etiqueta" => "6&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Tuberculous cervical lymphadenopathy"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "J&#46;F&#46; Newcombe"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Posgraduate Md J"
                        "fecha" => "1971"
                        "volumen" => "47"
                        "paginaInicial" => "713"
                        "paginaFinal" => "717"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            6 => array:3 [
              "identificador" => "bib0035"
              "etiqueta" => "7&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Lymph node tuberculosis&#58; a comparison of various methods of treatment"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "I&#46;A&#46; Campbell"
                            1 => "A&#46;J&#46; Dyson"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Tubercle"
                        "fecha" => "1977"
                        "volumen" => "58"
                        "paginaInicial" => "171"
                        "paginaFinal" => "179"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/601870"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            7 => array:3 [
              "identificador" => "bib0040"
              "etiqueta" => "8&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Lymph node tuberculosis&#58; a comparison of treatments 18 months after completion of chemotherapy"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "I&#46;A&#46; Campbell"
                            1 => "A&#46;J&#46; Dyson"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Tubercle"
                        "fecha" => "1979"
                        "volumen" => "60"
                        "paginaInicial" => "95"
                        "paginaFinal" => "98"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/473381"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            8 => array:3 [
              "identificador" => "bib0045"
              "etiqueta" => "9&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Modalites et bilan des traitements courts&#46; XVII Congres National Tuberculosis et Maladies Respiratoires"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "G&#46; Brouet"
                            1 => "G&#46; Rousell"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:3 [
                        "tituloSerie" => "Clermont Ferrand"
                        "fecha" => "1974"
                        "paginaInicial" => "27"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            9 => array:3 [
              "identificador" => "bib0050"
              "etiqueta" => "10&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Essan 6&#44; 9&#44; 12 M&#233;thodologie globale et synth&#232;se des r&#233;sultats"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "G&#46; Brouet"
                            1 => "G&#46; Roussell"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Rev Fran&#231; des Mal Resp"
                        "fecha" => "1977"
                        "volumen" => "1"
                        "paginaInicial" => "5"
                        "paginaFinal" => "13"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            10 => array:3 [
              "identificador" => "bib0055"
              "etiqueta" => "11&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Short duration chemotherapy of pulmonary tuberculosis&#46; A pilot trial"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "P&#46; Poppe de Figueiredo"
                            1 => "A&#46; Alvesbrito"
                            2 => "J&#46; Laborne Valle"
                            3 => "P&#46; Martius Tavares"
                            4 => "P&#46; Linbares Tranning"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:4 [
                        "tituloSerie" => "Bull UIAT"
                        "fecha" => "1974"
                        "volumen" => "49"
                        "paginaInicial" => "382"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            11 => array:3 [
              "identificador" => "bib0060"
              "etiqueta" => "12&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The modern management and therapy of pulmonary tuberculosis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "W&#46; Fox"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Proc Roy Soc of Med"
                        "fecha" => "1977"
                        "volumen" => "70"
                        "paginaInicial" => "4"
                        "paginaFinal" => "15"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            12 => array:3 [
              "identificador" => "bib0065"
              "etiqueta" => "13&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Short-course chemotherapy for pulmonary tuberculosis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "W&#46; Fox"
                            1 => "D&#46;A&#46; Mitchison"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "State of the Art&#46; Am Rev Respir Dis"
                        "fecha" => "1975"
                        "volumen" => "111"
                        "paginaInicial" => "325"
                        "paginaFinal" => "353"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            13 => array:3 [
              "identificador" => "bib0070"
              "etiqueta" => "14&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The current status of short-course chemotherapy"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "W&#46; Fox"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Tubercle"
                        "fecha" => "1979"
                        "volumen" => "60"
                        "paginaInicial" => "177"
                        "paginaFinal" => "190"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            14 => array:3 [
              "identificador" => "bib0075"
              "etiqueta" => "15&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Mecanismos bactericidas en la quimioterapia de corta duraci&#243;n"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "D&#46;A&#46; Mitchison"
                            1 => "F&#46;M&#46; Dickinson"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:3 [
                        "tituloSerie" => "Bull UIAT"
                        "fecha" => "1978"
                        "paginaInicial" => "53"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            15 => array:3 [
              "identificador" => "bib0080"
              "etiqueta" => "16&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Results of short course chemotherapy in extrapulmonary tuberculosis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "A&#46;K&#46; Dutt"
                            1 => "D&#46; Moers"
                            2 => "W&#46;W&#46; Stead"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Am Rev Respir Dis"
                        "fecha" => "1981"
                        "volumen" => "123"
                        "paginaInicial" => "255"
                        "paginaFinal" => "256"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            16 => array:3 [
              "identificador" => "bib0085"
              "etiqueta" => "17&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Tratamiento abreviado de la tuberculosis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "L&#46;J&#46; Gonz&#225;lez Muntaner"
                            1 => "O&#46; Palma Beltr&#225;n"
                            2 => "E&#46; Abbate"
                            3 => "A&#46; Dambrosi"
                            4 => "C&#46; Mosca"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Libro" => array:3 [
                        "fecha" => "1981"
                        "editorial" => "Ediciones H&#233;ctor Macchi"
                        "editorialLocalizacion" => "Buenos Aires"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            17 => array:3 [
              "identificador" => "bib0090"
              "etiqueta" => "18&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Tuberculosis of superficial lymph nodes"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "G&#46;D&#46; Summers"
                            1 => "M&#46;W&#46; McNicol"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Brit J Dis Chest"
                        "fecha" => "1980"
                        "volumen" => "74"
                        "paginaInicial" => "369"
                        "paginaFinal" => "373"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7213539"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            18 => array:3 [
              "identificador" => "bib0095"
              "etiqueta" => "19&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Tuberculosis ganglionar&#58; revisi&#243;n de 50 casos"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "F&#46; Cardellach"
                            1 => "A&#46; Pujol"
                            2 => "M&#46; Ingelmo"
                            3 => "C&#46; Picado"
                            4 => "A&#46; Balcells-Gorina"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Med Clin &#40;Barc&#41;"
                        "fecha" => "1983"
                        "volumen" => "81"
                        "paginaInicial" => "109"
                        "paginaFinal" => "111"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            19 => array:3 [
              "identificador" => "bib0100"
              "etiqueta" => "20&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Short course chemotherapy in pulmonary tuberculosis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "colaboracion" => "British Thoracic&#44; Tuberculosis&#44; Association"
                          "etal" => false
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Lancet"
                        "fecha" => "1976"
                        "volumen" => "2"
                        "paginaInicial" => "1102"
                        "paginaFinal" => "1104"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2572827"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            20 => array:3 [
              "identificador" => "bib0105"
              "etiqueta" => "21&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Isoniazid liver injury&#58; Clinical spectrum pathology and probable pathogenesis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "J&#46; Mitchell"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Ann Intern Med"
                        "fecha" => "1976"
                        "volumen" => "84"
                        "paginaInicial" => "181"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/766682"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            21 => array:3 [
              "identificador" => "bib0110"
              "etiqueta" => "22&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Tuberculosis&#46; Tuberculous glands in the neck"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "J&#46; Newcombe"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "British Journal of Hospital Medicine"
                        "fecha" => "1979"
                        "volumen" => "22"
                        "paginaInicial" => "553"
                        "paginaFinal" => "555"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/526691"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            22 => array:3 [
              "identificador" => "bib0115"
              "etiqueta" => "23&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Tuberculosis ganglionar cervical"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "C&#46; Gay Escoda"
                            1 => "J&#46;R&#46; Dom&#237;nguez Rodr&#237;guez"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Anales ORL Iber-Americanos"
                        "fecha" => "1979"
                        "volumen" => "3"
                        "paginaInicial" => "203"
                        "paginaFinal" => "215"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            23 => array:3 [
              "identificador" => "bib0120"
              "etiqueta" => "24&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "La evoluci&#243;n de la tuberculosis en Barcelona&#46; 60 a&#241;os de observaci&#243;n&#44; 1921-1981"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "P&#46; De March Ayuela"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Rev Enf T&#243;rax"
                        "fecha" => "1982"
                        "volumen" => "121"
                        "paginaInicial" => "53"
                        "paginaFinal" => "87"
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "es"
  "url" => "/03002896/0000002100000002/v1_201509151142/S0300289615321931/v1_201509151142/es/main.assets"
  "Apartado" => array:4 [
    "identificador" => "9277"
    "tipo" => "SECCION"
    "en" => array:2 [
      "titulo" => "Originales"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "en"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/03002896/0000002100000002/v1_201509151142/S0300289615321931/v1_201509151142/es/main.pdf?idApp=UINPBA00003Z&text.app=https://archbronconeumol.org/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289615321931?idApp=UINPBA00003Z"
]
Share
Journal Information
Vol. 21. Issue 2.
Pages 55-57 (March - April 1985)
Share
Share
Download PDF
More article options
Vol. 21. Issue 2.
Pages 55-57 (March - April 1985)
Full text access
Escrofulas: tratamiento controlado con un esquema de nueve meses
Scrofula: a nine-month controlled therapeutic trial
Visits
4713
E. Fite, R. Vidal, J. Ruiz-Manzano, L. Juanmiquel, J. Morera
Secció de Pneumologia. Ciutat Sanitària de la Vall d’Hebron. Barcelona
This item has received
Article information

Aportamos los resultados preliminares del tratamiento en 33 pacientes con adenitis tuberculosa periférica, con un esquema de nueve meses que incluía: rifampicina 600mg/día e isoniacida 300mg/día, más etambutol 25mg/kg/dia los dos primeros meses.

Durante el tratamiento, a partir del tercer mes, dos casos precisaron drenaje quirúrgico, uno desbridamiento de un absceso y otro exéresis quirúrgica. Al final del tratamiento los otros 27 casos habían evolucionado satisfactoriamente y no precisaron cirugía. No se presentaron complicaciones clínicas secundarias a la quimioterapia.

De los 33 pacientes, en 24 ha transcurrido más de un año desde que finalizaron el tratamiento. Uno de ellos no ha acudido a control, los 23 restantes se presentaron al año de terminar la terapéutica y en ninguno de ellos ha habido recidivas.

Con estos resultados pensamos que, al igual que en la tuberculosis pulmonar, la adenitis tuberculosa periférica puede ser tratada con prácticamente el 100% de curaciones con esquemas de nueve meses que incluyan rifampicina e isoniacida.

The authors present the preliminary results of a ninemonth treatment for peripheral tuberculous adenitis.

The trial included 33 patients who were given rifampicin at doses of 600mg/day and isoniazid at doses of 300mg/day plus 25mg/Kg/day ethambutol for the first two months.

After the third month of treatment two patients required surgical drainage and debridement of an abscess and further exeresis. The other 27 patients had a satisfactory response to the therapy and did not require surgical treatment. No side effects to the chemotherapy were seen in any of the patients.

Of the 24 patients out of the total 33 in the group, for whom more than one year has elapsed since finishing therapy, 23 were seen exactly one year later while one was lost to followup; there were no relapses.

These results strongly suggest that peripherical tuberculous adenitis may be treated succesfully —as in pulmonary tuberculosis— with a nine month schedule including rifampicin and isoniazids which elicit a cure rate of approximately 100%.

Full text is only aviable in PDF
Bibliografia
[1.]
G.S. Kilpatrick, A.C. Douglas.
Superficial glandular tuberculosis. Treatment with chemotherapy.
Brit Med J, 2 (1957), pp. 612-614
[2.]
J.M. Schless, J.A. Wier.
The current status and treatment of lymphatic tuberculosis.
Am Rev Tuberculosis, 76 (1957), pp. 811-831
[3.]
P.M.S. Gillam, J.P. Knowles.
The treatment of tuberculous lymphadenitis.
Tubercle, 44 (1963), pp. 112-118
[4.]
H.S. Fraser.
Peripheral tuberculous lymphadenitis.
Brit J Dis Chest, 59 (1965), pp. 164-172
[5.]
P.B. Iles, P.A. Emerson.
Tuberculous Lymphadenitis.
Brit Med J, 1 (1974), pp. 143-145
[6.]
J.F. Newcombe.
Tuberculous cervical lymphadenopathy.
Posgraduate Md J, 47 (1971), pp. 713-717
[7.]
I.A. Campbell, A.J. Dyson.
Lymph node tuberculosis: a comparison of various methods of treatment.
Tubercle, 58 (1977), pp. 171-179
[8.]
I.A. Campbell, A.J. Dyson.
Lymph node tuberculosis: a comparison of treatments 18 months after completion of chemotherapy.
Tubercle, 60 (1979), pp. 95-98
[9.]
G. Brouet, G. Rousell.
Modalites et bilan des traitements courts. XVII Congres National Tuberculosis et Maladies Respiratoires.
Clermont Ferrand, (1974), pp. 27
[10.]
G. Brouet, G. Roussell.
Essan 6, 9, 12 Méthodologie globale et synthèse des résultats.
Rev Franç des Mal Resp, 1 (1977), pp. 5-13
[11.]
P. Poppe de Figueiredo, A. Alvesbrito, J. Laborne Valle, P. Martius Tavares, P. Linbares Tranning.
Short duration chemotherapy of pulmonary tuberculosis. A pilot trial.
Bull UIAT, 49 (1974), pp. 382
[12.]
W. Fox.
The modern management and therapy of pulmonary tuberculosis.
Proc Roy Soc of Med, 70 (1977), pp. 4-15
[13.]
W. Fox, D.A. Mitchison.
Short-course chemotherapy for pulmonary tuberculosis.
State of the Art. Am Rev Respir Dis, 111 (1975), pp. 325-353
[14.]
W. Fox.
The current status of short-course chemotherapy.
Tubercle, 60 (1979), pp. 177-190
[15.]
D.A. Mitchison, F.M. Dickinson.
Mecanismos bactericidas en la quimioterapia de corta duración.
Bull UIAT, (1978), pp. 53
[16.]
A.K. Dutt, D. Moers, W.W. Stead.
Results of short course chemotherapy in extrapulmonary tuberculosis.
Am Rev Respir Dis, 123 (1981), pp. 255-256
[17.]
L.J. González Muntaner, O. Palma Beltrán, E. Abbate, A. Dambrosi, C. Mosca.
Tratamiento abreviado de la tuberculosis.
Ediciones Héctor Macchi, (1981),
[18.]
G.D. Summers, M.W. McNicol.
Tuberculosis of superficial lymph nodes.
Brit J Dis Chest, 74 (1980), pp. 369-373
[19.]
F. Cardellach, A. Pujol, M. Ingelmo, C. Picado, A. Balcells-Gorina.
Tuberculosis ganglionar: revisión de 50 casos.
Med Clin (Barc), 81 (1983), pp. 109-111
[20.]
British Thoracic, Tuberculosis, Association.
Short course chemotherapy in pulmonary tuberculosis.
Lancet, 2 (1976), pp. 1102-1104
[21.]
J. Mitchell.
Isoniazid liver injury: Clinical spectrum pathology and probable pathogenesis.
Ann Intern Med, 84 (1976), pp. 181
[22.]
J. Newcombe.
Tuberculosis. Tuberculous glands in the neck.
British Journal of Hospital Medicine, 22 (1979), pp. 553-555
[23.]
C. Gay Escoda, J.R. Domínguez Rodríguez.
Tuberculosis ganglionar cervical.
Anales ORL Iber-Americanos, 3 (1979), pp. 203-215
[24.]
P. De March Ayuela.
La evolución de la tuberculosis en Barcelona. 60 años de observación, 1921-1981.
Rev Enf Tórax, 121 (1982), pp. 53-87
Copyright © 1985. Sociedad Española de Neumología y Cirugía Torácica
Archivos de Bronconeumología
Article options
Tools

Are you a health professional able to prescribe or dispense drugs?